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The role of the hydrophilic Asn230 residue of the mu-opioid receptor in the potency of various opioid agonists. , Pil J, Tytgat J., Br J Pharmacol. October 1, 2001; 134 (3): 496-506.
G protein-gated inwardly rectifying potassium channels are targets for volatile anesthetics. , Weigl LG, Schreibmayer W., Mol Pharmacol. August 1, 2001; 60 (2): 282-9.
Differential effects of general anesthetics on G protein-coupled inwardly rectifying and other potassium channels. , Yamakura T, Lewohl JM, Harris RA., Anesthesiology. July 1, 2001; 95 (1): 144-53.
Mechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying K+ channels. , Zhou W, Arrabit C, Choe S, Slesinger PA., Proc Natl Acad Sci U S A. May 22, 2001; 98 (11): 6482-7.
Functional properties of a truncated recombinant GIRK5 potassium channel. , Salvador C, Martinez M, Mora SI, Egido W, Farias JM, Gamba G, Escobar LI., Biochim Biophys Acta. May 2, 2001; 1512 (1): 135-47.
Yeast screen for constitutively active mutant G protein-activated potassium channels. , Yi BA, Lin YF, Jan YN, Jan LY., Neuron. March 1, 2001; 29 (3): 657-67.
Ion selectivity filter regulates local anesthetic inhibition of G-protein-gated inwardly rectifying K+ channels. , Slesinger PA., Biophys J. February 1, 2001; 80 (2): 707-18.
G-protein mediated gating of inward-rectifier K+ channels. , Mark MD, Herlitze S., Eur J Biochem. October 1, 2000; 267 (19): 5830-6.
Changes in GIRK1/ GIRK2 deactivation kinetics and basal activity in the presence and absence of RGS4. , Ulens C, Daenens P, Tytgat J., Life Sci. September 29, 2000; 67 (19): 2305-17.
Interaction of p-fluorofentanyl on cloned human opioid receptors and exploration of the role of Trp-318 and His-319 in mu-opioid receptor selectivity. , Ulens C, Van Boven M, Daenens P, Tytgat J., J Pharmacol Exp Ther. September 1, 2000; 294 (3): 1024-33.
TrkB activation by brain-derived neurotrophic factor inhibits the G protein-gated inward rectifier Kir3 by tyrosine phosphorylation of the channel. , Rogalski SL, Appleyard SM, Pattillo A, Terman GW, Chavkin C., J Biol Chem. August 18, 2000; 275 (33): 25082-8.
Impermeability of the GIRK2 weaver channel to divalent cations. , Hou P, Di A, Huang P, Hansen CB , Nelson DJ., Am J Physiol Cell Physiol. May 1, 2000; 278 (5): C1038-46.
Heterologous facilitation of G protein-activated K(+) channels by beta-adrenergic stimulation via cAMP-dependent protein kinase. , Müllner C, Vorobiov D, Bera AK, Uezono Y, Yakubovich D, Frohnwieser-Steinecker B, Dascal N , Schreibmayer W., J Gen Physiol. May 1, 2000; 115 (5): 547-58.
Inhibition by various antipsychotic drugs of the G-protein-activated inwardly rectifying K(+) ( GIRK) channels expressed in xenopus oocytes. , Kobayashi T, Ikeda K, Kumanishi T., Br J Pharmacol. April 1, 2000; 129 (8): 1716-22.
The dual modulation of GIRK1/ GIRK2 channels by opioid receptor ligands. , Ulens C, Daenens P, Tytgat J., Eur J Pharmacol. December 3, 1999; 385 (2-3): 239-45.
Ethanol opens G-protein-activated inwardly rectifying K+ channels. , Kobayashi T, Ikeda K, Kojima H, Niki H, Yano R, Yoshioka T, Kumanishi T., Nat Neurosci. December 1, 1999; 2 (12): 1091-7.
G-protein-coupled inwardly rectifying potassium channels are targets of alcohol action. , Lewohl JM, Wilson WR , Mayfield RD, Brozowski SJ, Morrisett RA, Harris RA., Nat Neurosci. December 1, 1999; 2 (12): 1084-90.
Molecular cloning and characterization of a novel splicing variant of the Kir3.2 subunit predominantly expressed in mouse testis. , Inanobe A, Horio Y, Fujita A, Tanemoto M, Hibino H, Inageda K, Kurachi Y., J Physiol. November 15, 1999; 521 Pt 1 19-30.
Molecular mechanism for sodium-dependent activation of G protein-gated K+ channels. , Ho IH, Murrell-Lagnado RD., J Physiol. November 1, 1999; 520 Pt 3 645-51.
The inwardly rectifying K(+) channel subunit GIRK1 rescues the GIRK2 weaver phenotype. , Hou P, Yan S , Tang W, Nelson DJ., J Neurosci. October 1, 1999; 19 (19): 8327-36.
Bombesin receptors inhibit G protein-coupled inwardly rectifying K+ channels expressed in Xenopus oocytes through a protein kinase C-dependent pathway. , Stevens EB, Shah BS, Pinnock RD, Lee K., Mol Pharmacol. June 1, 1999; 55 (6): 1020-7.
Functional expression and characterization of G-protein-gated inwardly rectifying K+ channels containing GIRK3. , Jelacic TM, Sims SM, Clapham DE., J Membr Biol. May 15, 1999; 169 (2): 123-9.
Molecular determinants for sodium-dependent activation of G protein-gated K+ channels. , Ho IH, Murrell-Lagnado RD., J Biol Chem. March 26, 1999; 274 (13): 8639-48.
Characterization of G-protein-gated K+ channels composed of Kir3.2 subunits in dopaminergic neurons of the substantia nigra. , Inanobe A, Yoshimoto Y, Horio Y, Morishige KI, Hibino H, Matsumoto S, Tokunaga Y, Maeda T, Hata Y, Takai Y, Kurachi Y., J Neurosci. February 1, 1999; 19 (3): 1006-17.
Activation of inwardly rectifying K+ channels by GABA-B receptors expressed in Xenopus oocytes. , Uezono Y, Akihara M, Kaibara M, Kawano C, Shibuya I, Ueda Y, Yanagihara N, Toyohira Y, Yamashita H, Taniyama K, Izumi F., Neuroreport. March 9, 1998; 9 (4): 583-7.
Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma. , Huang CL, Feng S, Hilgemann DW., Nature. February 19, 1998; 391 (6669): 803-6.
Defective gamma-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice. , Slesinger PA, Stoffel M, Jan YN, Jan LY., Proc Natl Acad Sci U S A. October 28, 1997; 94 (22): 12210-7.
Identification of regions that regulate the expression and activity of G protein-gated inward rectifier K+ channels in Xenopus oocytes. , Stevens EB, Woodward R, Ho IH, Murrell-Lagnado R., J Physiol. September 15, 1997; 503 ( Pt 3) 547-62.
Activation of heteromeric G protein-gated inward rectifier K+ channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons. , Ehrengruber MU, Doupnik CA, Xu Y , Xu Y , Garvey J, Jasek MC, Lester HA, Davidson N., Proc Natl Acad Sci U S A. June 24, 1997; 94 (13): 7070-5.
Molecular determinants for assembly of G-protein-activated inwardly rectifying K+ channels. , Woodward R, Stevens EB, Murrell-Lagnado RD., J Biol Chem. April 18, 1997; 272 (16): 10823-30.
Positive and negative coupling of the metabotropic glutamate receptors to a G protein-activated K+ channel, GIRK, in Xenopus oocytes. , Sharon D, Vorobiov D, Dascal N ., J Gen Physiol. April 1, 1997; 109 (4): 477-90.
Specific regions of heteromeric subunits involved in enhancement of G protein-gated K+ channel activity. , Chan KW, Sui JL, Vivaudou M, Logothetis DE., J Biol Chem. March 7, 1997; 272 (10): 6548-55.
Subunit interactions in the assembly of neuronal Kir3.0 inwardly rectifying K+ channels. , Döring F, Wischmeyer E, Spauschus A, Thomzig A, Veh R, Karschin A., Mol Cell Neurosci. January 1, 1997; 9 (3): 194-206.
A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation. , Silverman SK, Kofuji P, Dougherty DA, Davidson N, Lester HA., Proc Natl Acad Sci U S A. December 24, 1996; 93 (26): 15429-34.
Control of channel activity through a unique amino acid residue of a G protein-gated inwardly rectifying K+ channel subunit. , Chan KW, Sui JL, Vivaudou M, Logothetis DE., Proc Natl Acad Sci U S A. November 26, 1996; 93 (24): 14193-8.
The weaver mutation changes the ion selectivity of the affected inwardly rectifying potassium channel GIRK2. , Tong Y, Wei J, Zhang S, Strong JA, Dlouhy SR, Hodes ME, Ghetti B, Yu L., FEBS Lett. July 15, 1996; 390 (1): 63-8.
Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells. , Kofuji P, Hofer M, Millen KJ, Millonig JH, Davidson N, Lester HA, Hatten ME., Neuron. May 1, 1996; 16 (5): 941-52.
Functional effects of the mouse weaver mutation on G protein-gated inwardly rectifying K+ channels. , Slesinger PA, Patil N, Liao YJ, Jan YN, Jan LY, Cox DR., Neuron. February 1, 1996; 16 (2): 321-31.
The K+ channel inward rectifier subunits form a channel similar to neuronal G protein-gated K+ channel. , Velimirovic BM, Gordon EA, Lim NF, Navarro B, Clapham DE., FEBS Lett. January 22, 1996; 379 (1): 31-7.
A novel ubiquitously distributed isoform of GIRK2 (GIRK2B) enhances GIRK1 expression of the G-protein-gated K+ current in Xenopus oocytes. , Isomoto S, Kondo C, Takahashi N, Matsumoto S, Yamada M, Takumi T, Horio Y, Kurachi Y., Biochem Biophys Res Commun. January 5, 1996; 218 (1): 286-91.
Dominant negative chimeras provide evidence for homo and heteromultimeric assembly of inward rectifier K+ channel proteins via their N-terminal end. , Fink M, Duprat F, Heurteaux C, Lesage F , Romey G, Barhanin J , Lazdunski M., FEBS Lett. January 2, 1996; 378 (1): 64-8.
Molecular properties of neuronal G-protein-activated inwardly rectifying K+ channels. , Lesage F , Guillemare E, Fink M, Duprat F, Heurteaux C, Fosset M, Romey G, Barhanin J , Lazdunski M., J Biol Chem. December 1, 1995; 270 (48): 28660-7.
Pancreatic islet cells express a family of inwardly rectifying K+ channel subunits which interact to form G-protein-activated channels. , Ferrer J, Nichols CG, Makhina EN, Salkoff L, Bernstein J, Gerhard D, Wasson J, Ramanadham S, Permutt A., J Biol Chem. November 3, 1995; 270 (44): 26086-91.
Heterologous multimeric assembly is essential for K+ channel activity of neuronal and cardiac G-protein-activated inward rectifiers. , Duprat F, Lesage F , Guillemare E, Fink M, Hugnot JP, Bigay J, Lazdunski M, Romey G, Barhanin J ., Biochem Biophys Res Commun. July 17, 1995; 212 (2): 657-63.
Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by G beta gamma subunits and function as heteromultimers. , Kofuji P, Davidson N, Lester HA., Proc Natl Acad Sci U S A. July 3, 1995; 92 (14): 6542-6.
Cloning and functional expression of the cDNA encoding an inwardly-rectifying potassium channel expressed in pancreatic beta-cells and in the brain. , Bond CT, Ammälä C, Ashfield R, Blair TA, Gribble F, Khan RN, Lee K, Proks P, Rowe IC, Sakura H., FEBS Lett. June 19, 1995; 367 (1): 61-6.