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Summary Expression Phenotypes Gene Literature (538) GO Terms (29) Nucleotides (79) Proteins (47) Interactants (1218) Wiki
XB-GENEPAGE-487168

Papers associated with nodal1



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A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction., Kim RH, Wang D, Tsang M, Martin J, Huff C, de Caestecker MP, Parks WT, Meng X, Lechleider RJ, Wang T, Roberts AB., Genes Dev. July 1, 2000; 14 (13): 1605-16.   


Phenotypic effects in Xenopus and zebrafish suggest that one-eyed pinhead functions as antagonist of BMP signalling., Kiecker C, Müller F, Wu W, Glinka A, Strähle U, Niehrs C., Mech Dev. June 1, 2000; 94 (1-2): 37-46.   


Activin/nodal responsiveness and asymmetric expression of a Xenopus nodal-related gene converge on a FAST-regulated module in intron 1., Osada SI, Saijoh Y, Frisch A, Yeo CY, Adachi H, Watanabe M, Whitman M, Hamada H, Wright CV., Development. June 1, 2000; 127 (11): 2503-14.

The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination., Murcia NS, Richards WG, Yoder BK, Mucenski ML, Dunlap JR, Woychik RP., Development. June 1, 2000; 127 (11): 2347-55.

More than 95% reversal of left-right axis induced by right-sided hypodermic microinjection of activin into Xenopus neurula embryos., Toyoizumi R, Mogi K, Takeuchi S., Dev Biol. May 15, 2000; 221 (2): 321-36.   


Primary structure requirements for Xenopus nodal-related 3 and a comparison with regions required by Xenopus nodal-related 2., Ezal CH, Marion CD, Smith WC., J Biol Chem. May 12, 2000; 275 (19): 14124-31.

Nodal-related signals establish mesendodermal fate and trunk neural identity in zebrafish., Feldman B, Dougan ST, Schier AF, Talbot WS., Curr Biol. May 4, 2000; 10 (9): 531-4.

Initiation of eukaryotic DNA replication: origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase alpha., Walter J, Newport J., Mol Cell. April 1, 2000; 5 (4): 617-27.

Cerberus-like is a secreted BMP and nodal antagonist not essential for mouse development., Belo JA, Bachiller D, Agius E, Kemp C, Borges AC, Marques S, Piccolo S, De Robertis EM., Genesis. April 1, 2000; 26 (4): 265-70.

Mechanisms of left-right determination in vertebrates., Capdevila J, Vogan KJ, Tabin CJ, Izpisúa Belmonte JC., Cell. March 31, 2000; 101 (1): 9-21.   


Regulation of the early expression of the Xenopus nodal-related 1 gene, Xnr1., Hyde CE, Old RW., Development. March 1, 2000; 127 (6): 1221-9.   


Endodermal Nodal-related signals and mesoderm induction in Xenopus., Agius E, Oelgeschläger M, Wessely O, Kemp C, De Robertis EM., Development. March 1, 2000; 127 (6): 1173-83.   


Mesendoderm and left-right brain, heart and gut development are differentially regulated by pitx2 isoforms., Essner JJ, Branford WW, Zhang J, Yost HJ., Development. March 1, 2000; 127 (5): 1081-93.   


The lefty-related factor Xatv acts as a feedback inhibitor of nodal signaling in mesoderm induction and L-R axis development in xenopus., Cheng AM, Thisse B, Thisse C, Wright CV., Development. March 1, 2000; 127 (5): 1049-61.   


Nodal signaling patterns the organizer., Gritsman K, Talbot WS, Schier AF., Development. March 1, 2000; 127 (5): 921-32.

Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2., Saijoh Y, Adachi H, Sakuma R, Yeo CY, Yashiro K, Watanabe M, Hashiguchi H, Mochida K, Ohishi S, Kawabata M, Miyazono K, Whitman M, Hamada H., Mol Cell. January 1, 2000; 5 (1): 35-47.   


Embryonic origins of spleen asymmetry., Patterson KD, Drysdale TA, Krieg PA., Development. January 1, 2000; 127 (1): 167-75.   


In vitro and in vivo characterization of conantokin-R, a selective NMDA receptor antagonist isolated from the venom of the fish-hunting snail Conus radiatus., White HS, McCabe RT, Armstrong H, Donevan SD, Cruz LJ, Abogadie FC, Torres J, Rivier JE, Paarmann I, Hollmann M, Olivera BM., J Pharmacol Exp Ther. January 1, 2000; 292 (1): 425-32.

The Yin-Yang of TCF/beta-catenin signaling., Barker N, Morin PJ, Clevers H., Adv Cancer Res. January 1, 2000; 77 1-24.

In Xenopus embryos, BMP heterodimers are not required for mesoderm induction, but BMP activity is necessary for dorsal/ventral patterning., Eimon PM, Harland RM., Dev Biol. December 1, 1999; 216 (1): 29-40.   


Mesoderm induction in Xenopus is a zygotic event regulated by maternal VegT via TGFbeta growth factors., Kofron M, Demel T, Xanthos J, Lohr J, Sun B, Sive H, Osada S, Wright C, Wylie C, Heasman J., Development. December 1, 1999; 126 (24): 5759-70.

Cardiac looping and the vertebrate left-right axis: antagonism of left-sided Vg1 activity by a right-sided ALK2-dependent BMP pathway., Ramsdell AF, Yost HJ., Development. December 1, 1999; 126 (23): 5195-205.   


A mutation in the glycine binding pocket of the N-methyl-D-aspartate receptor NR1 subunit alters agonist efficacy., Wood MW, VanDongen HM, VanDongen AM., Brain Res Mol Brain Res. November 10, 1999; 73 (1-2): 189-92.

Mode of action of VegT in mesoderm and endoderm formation., Clements D, Friday RV, Woodland HR., Development. November 1, 1999; 126 (21): 4903-11.

Gap junction-mediated transfer of left-right patterning signals in the early chick blastoderm is upstream of Shh asymmetry in the node., Levin M, Mercola M., Development. November 1, 1999; 126 (21): 4703-14.   

A two-step model for the fate determination of presumptive endodermal blastomeres in Xenopus embryos., Yasuo H, Lemaire P., Curr Biol. August 26, 1999; 9 (16): 869-79.   


4-Hydroxy-1-[2-(4-hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)piperidine: a novel, potent, and selective NR1/2B NMDA receptor antagonist., Zhou ZL, Cai SX, Whittemore ER, Konkoy CS, Espitia SA, Tran M, Rock DM, Coughenour LL, Hawkinson JE, Boxer PA, Bigge CF, Wise LD, Weber E, Woodward RM, Keana JF., J Med Chem. July 29, 1999; 42 (15): 2993-3000.

The SIL gene is required for mouse embryonic axial development and left-right specification., Izraeli S, Lowe LA, Bertness VL, Good DJ, Dorward DW, Kirsch IR, Kuehn MR., Nature. June 17, 1999; 399 (6737): 691-4.

Xenopus nodal-related signaling is essential for mesendodermal patterning during early embryogenesis., Osada SI, Wright CV., Development. June 1, 1999; 126 (14): 3229-40.   


A regulatory domain (R1-R2) in the amino terminus of the N-methyl-D-aspartate receptor: effects of spermine, protons, and ifenprodil, and structural similarity to bacterial leucine/isoleucine/valine binding protein., Masuko T, Kashiwagi K, Kuno T, Nguyen ND, Pahk AJ, Fukuchi J, Igarashi K, Williams K., Mol Pharmacol. June 1, 1999; 55 (6): 957-69.

Retinoic acid is required in the mouse embryo for left-right asymmetry determination and heart morphogenesis., Chazaud C, Chambon P, Dollé P., Development. June 1, 1999; 126 (12): 2589-96.

Anterior endomesoderm specification in Xenopus by Wnt/beta-catenin and TGF-beta signalling pathways., Zorn AM, Butler K, Gurdon JB., Dev Biol. May 15, 1999; 209 (2): 282-97.   


Subtype-selective antagonism of N-methyl-D-aspartate receptors by felbamate: insights into the mechanism of action., Kleckner NW, Glazewski JC, Chen CC, Moscrip TD., J Pharmacol Exp Ther. May 1, 1999; 289 (2): 886-94.

The EGF-CFC protein one-eyed pinhead is essential for nodal signaling., Gritsman K, Zhang J, Cheng S, Heckscher E, Talbot WS, Schier AF., Cell. April 2, 1999; 97 (1): 121-32.

derrière: a TGF-beta family member required for posterior development in Xenopus., Sun BI, Bush SM, Collins-Racie LA, LaVallie ER, DiBlasio-Smith EA, Wolfman NM, McCoy JM, Sive HL., Development. April 1, 1999; 126 (7): 1467-82.   


A molecular basis for Smad specificity., Lagna G, Hemmati-Brivanlou A., Dev Dyn. March 1, 1999; 214 (3): 269-77.

The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping., Campione M, Steinbeisser H, Schweickert A, Deissler K, van Bebber F, Lowe LA, Nowotschin S, Viebahn C, Haffter P, Kuehn MR, Blum M., Development. March 1, 1999; 126 (6): 1225-34.   


The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals., Piccolo S, Agius E, Leyns L, Bhattacharyya S, Grunz H, Bouwmeester T, De Robertis EM., Nature. February 25, 1999; 397 (6721): 707-10.

Protein kinase C modulation of recombinant NMDA receptor currents: roles for the C-terminal C1 exon and calcium ions., Logan SM, Rivera FE, Leonard JP., J Neurosci. February 1, 1999; 19 (3): 974-86.

[The head inducer Cerberus in a multivalent extracellular inhibitor]., Agius PE, Piccolo S, De Robertis EM., J Soc Biol. January 1, 1999; 193 (4-5): 347-54.

Mutation of structural determinants lining the N-methyl-D-aspartate receptor channel differentially affects phencyclidine block and spermine potentiation and block., Zheng X, Zhang L, Wang AP, Araneda RC, Lin Y, Zukin RS, Bennett MV., Neuroscience. January 1, 1999; 93 (1): 125-34.

Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin., Roebroek AJ, Umans L, Pauli IG, Robertson EJ, van Leuven F, Van de Ven WJ, Constam DB., Development. December 1, 1998; 125 (24): 4863-76.

Gap junctions are involved in the early generation of left-right asymmetry., Levin M, Mercola M., Dev Biol. November 1, 1998; 203 (1): 90-105.   


Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling., Sampath K, Rubinstein AL, Cheng AM, Liang JO, Fekany K, Solnica-Krezel L, Korzh V, Halpern ME, Wright CV., Nature. September 10, 1998; 395 (6698): 185-9.

Intracellular calcium enhances the ethanol sensitivity of NMDA receptors through an interaction with the C0 domain of the NR1 subunit., Mirshahi T, Anders DL, Ronald KM, Woodward JJ., J Neurochem. September 1, 1998; 71 (3): 1095-107.

Neurosteroid modulation of recombinant ionotropic glutamate receptors., Yaghoubi N, Malayev A, Russek SJ, Gibbs TT, Farb DH., Dev Biol. August 24, 1998; 803 (1-2): 153-60.

Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit., Traynelis SF, Burgess MF, Zheng F, Lyuboslavsky P, Powers JL., J Neurosci. August 15, 1998; 18 (16): 6163-75.

Pitx2 determines left-right asymmetry of internal organs in vertebrates., Ryan AK, Blumberg B, Rodriguez-Esteban C, Yonei-Tamura S, Tamura K, Tamura K, Tsukui T, de la Peña J, Sabbagh W, Greenwald J, Choe S, Norris DP, Robertson EJ, Evans RM, Rosenfeld MG, Izpisúa Belmonte JC., Nature. August 6, 1998; 394 (6693): 545-51.

Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry., Rebagliati MR, Toyama R, Fricke C, Haffter P, Dawid IB., Dev Biol. July 15, 1998; 199 (2): 261-72.

Mutant Vg1 ligands disrupt endoderm and mesoderm formation in Xenopus embryos., Joseph EM, Melton DA., Development. July 1, 1998; 125 (14): 2677-85.   

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