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Summary Expression Phenotypes Gene Literature (68) GO Terms (17) Nucleotides (291) Proteins (88) Interactants (382) Wiki

Papers associated with pou2f1

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In vitro modeling of cranial placode differentiation: Recent advances, challenges, and perspectives., Griffin C, Saint-Jeannet JP., Dev Biol. February 1, 2024; 506 20-30.

Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1., Chen M, Neul C, Schaeffeler E, Frisch F, Winter S, Schwab M, Koepsell H, Hu S, Laufer S, Baker SD, Sparreboom A, Nies AT., Clin Pharmacol Ther. January 1, 2020; 107 (1): 227-237.

Imatinib Uptake into Cells is Not Mediated by Organic Cation Transporters OCT1, OCT2, or OCT3, But is Influenced by Extracellular pH., Blanc Mettral J, Faller N, Cruchon S, Sottas L, Buclin T, Schild L, Choong E, Nahimana A, Decosterd LA., Drug Metab Lett. January 1, 2019; 13 (2): 102-110.

Comprehensive Substrate Characterization of 22 Antituberculosis Drugs for Multiple Solute Carrier (SLC) Uptake Transporters In Vitro., Parvez MM, Kaisar N, Shin HJ, Lee YJ, Shin JG., Antimicrob Agents Chemother. August 27, 2018; 62 (9):

In vitro and physiologically-based pharmacokinetic based assessment of drug-drug interaction potential of canagliflozin., Mamidi RNVS, Dallas S, Sensenhauser C, Lim HK, Scheers E, Verboven P, Cuyckens F, Leclercq L, Evans DC, Kelley MF, Johnson MD, Snoeys J., Br J Clin Pharmacol. May 1, 2017; 83 (5): 1082-1096.

High-throughput analysis reveals novel maternal germline RNAs crucial for primordial germ cell preservation and proper migration., Owens DA, Butler AM, Aguero TH, Newman KM, Van Booven D, King ML., Development. January 15, 2017; 144 (2): 292-304.                                                                                        

Retention of duplicated ITAM-containing transmembrane signaling subunits in the tetraploid amphibian species Xenopus laevis., Guselnikov SV, Grayfer L, De Jesús Andino F, Rogozin IB, Robert J, Taranin AV., Dev Comp Immunol. November 1, 2015; 53 (1): 158-68.            

Expression, sorting and transport studies for the orphan carrier SLC10A4 in neuronal and non-neuronal cell lines and in Xenopus laevis oocytes., Schmidt S, Moncada M, Burger S, Geyer J., BMC Neurosci. June 19, 2015; 16 35.                        

Edoxaban transport via P-glycoprotein is a key factor for the drug's disposition., Mikkaichi T, Yoshigae Y, Masumoto H, Imaoka T, Rozehnal V, Fischer T, Okudaira N, Izumi T., Drug Metab Dispos. April 1, 2014; 42 (4): 520-8.

Cellular uptake of imatinib into leukemic cells is independent of human organic cation transporter 1 (OCT1)., Nies AT, Schaeffeler E, van der Kuip H, Cascorbi I, Bruhn O, Kneba M, Pott C, Hofmann U, Volk C, Hu S, Baker SD, Sparreboom A, Ruth P, Koepsell H, Schwab M., Clin Cancer Res. February 15, 2014; 20 (4): 985-94.

Expression of SLC22A1 variants may affect the response of hepatocellular carcinoma and cholangiocarcinoma to sorafenib., Herraez E, Lozano E, Macias RI, Vaquero J, Bujanda L, Banales JM, Marin JJ, Briz O., Hepatology. September 1, 2013; 58 (3): 1065-73.

Polyamine transport by the polyspecific organic cation transporters OCT1, OCT2, and OCT3., Sala-Rabanal M, Li DC, Dake GR, Kurata HT, Inyushin M, Skatchkov SN, Nichols CG., Mol Pharm. April 1, 2013; 10 (4): 1450-8.

Transcription factors involved in lens development from the preplacodal ectoderm., Ogino H, Ochi H, Reza HM, Yasuda K., Dev Biol. March 15, 2012; 363 (2): 333-47.      

The large extracellular loop of organic cation transporter 1 influences substrate affinity and is pivotal for oligomerization., Keller T, Egenberger B, Gorboulev V, Bernhard F, Uzelac Z, Gorbunov D, Wirth C, Koppatz S, Dötsch V, Hunte C, Sitte HH, Koepsell H., J Biol Chem. October 28, 2011; 286 (43): 37874-86.

Dynamic regulation of Oct1 during mitosis by phosphorylation and ubiquitination., Kang J, Goodman B, Zheng Y, Tantin D., PLoS One. January 1, 2011; 6 (8): e23872.              

FoxA1 binding directs chromatin structure and the functional response of a glucocorticoid receptor-regulated promoter., Belikov S, Astrand C, Wrange O., Mol Cell Biol. October 1, 2009; 29 (20): 5413-25.

Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters., Hu S, Chen Z, Franke R, Orwick S, Zhao M, Rudek MA, Sparreboom A, Baker SD., Clin Cancer Res. October 1, 2009; 15 (19): 6062-9.

Histone acetylation characterizes chromatin presetting by NF1 and Oct1 and enhances glucocorticoid receptor binding to the MMTV promoter., Astrand C, Belikov S, Wrange O., Exp Cell Res. September 10, 2009; 315 (15): 2604-15.

A microarray screen for direct targets of Zic1 identifies an aquaporin gene, aqp-3b, expressed in the neural folds., Cornish EJ, Hassan SM, Martin JD, Li S, Merzdorf CS., Dev Dyn. May 1, 2009; 238 (5): 1179-94.                

Histone 2B (H2B) expression is confined to a proper NAD+/NADH redox status., Dai RP, Yu FX, Goh SR, Chng HW, Tan YL, Fu JL, Zheng L, Luo Y., J Biol Chem. October 3, 2008; 283 (40): 26894-901.

Genetic variants of organic cation transporter 2 (OCT2) significantly reduce metformin uptake in oocytes., Song IS, Shin HJ, Shin JG., Xenobiotica. September 1, 2008; 38 (9): 1252-62.

Interaction of imatinib with human organic ion carriers., Hu S, Franke RM, Filipski KK, Hu C, Orwick SJ, de Bruijn EA, Burger H, Baker SD, Sparreboom A., Clin Cancer Res. May 15, 2008; 14 (10): 3141-8.

The POU homeobox protein Oct-1 regulates radial glia formation downstream of Notch signaling., Kiyota T, Kato A, Altmann CR, Kato Y., Dev Biol. March 15, 2008; 315 (2): 579-92.      

Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity., Sturm A, Gorboulev V, Gorbunov D, Keller T, Volk C, Schmitt BM, Schlachtbauer P, Ciarimboli G, Koepsell H., Am J Physiol Renal Physiol. September 1, 2007; 293 (3): F767-79.

Variants in the SLCO1B3 gene: interethnic distribution and association with paclitaxel pharmacokinetics., Smith NF, Marsh S, Scott-Horton TJ, Hamada A, Mielke S, Mross K, Figg WD, Verweij J, McLeod HL, Sparreboom A., Clin Pharmacol Ther. January 1, 2007; 81 (1): 76-82.

Expression of transporters potentially involved in the targeting of cytostatic bile acid derivatives to colon cancer and polyps., Ballestero MR, Monte MJ, Briz O, Jimenez F, Gonzalez-San Martin F, Marin JJ., Biochem Pharmacol. September 14, 2006; 72 (6): 729-38.

Comparative genomics on SOX2 orthologs., Katoh Y, Katoh M., Oncol Rep. September 1, 2005; 14 (3): 797-800.

An Oct-1 binding site mediates activation of the gata2 promoter by BMP signaling., Oren T, Torregroza I, Evans T., Nucleic Acids Res. August 1, 2005; 33 (13): 4357-67.              

Comparative genomics on Dkk1 orthologs., Katoh Y, Katoh M., Int J Oncol. July 1, 2005; 27 (1): 275-9.

Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium., Lips KS, Volk C, Schmitt BM, Pfeil U, Arndt P, Miska D, Ermert L, Kummer W, Koepsell H., Am J Respir Cell Mol Biol. July 1, 2005; 33 (1): 79-88.

A consensus Oct1 binding site is required for the activity of the Xenopus Cdx4 promoter., Reece-Hoyes JS, Keenan ID, Pownall ME, Isaacs HV., Dev Biol. June 15, 2005; 282 (2): 509-23.              

Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney., Ishiguro N, Saito A, Yokoyama K, Morikawa M, Igarashi T, Tamai I., Drug Metab Dispos. April 1, 2005; 33 (4): 495-9.

Nuclear factor 1 and octamer transcription factor 1 binding preset the chromatin structure of the mouse mammary tumor virus promoter for hormone induction., Belikov S, Holmqvist PH, Astrand C, Wrange O., J Biol Chem. November 26, 2004; 279 (48): 49857-67.

Characterization of snRNA and snRNA-type genes in the pufferfish Fugu rubripes., Myslinski E, Krol A, Carbon P., Gene. April 14, 2004; 330 149-58.

Chromatin-mediated restriction of nuclear factor 1/CTF binding in a repressed and hormone-activated promoter in vivo., Belikov S, Astrand C, Holmqvist PH, Wrange O., Mol Cell Biol. April 1, 2004; 24 (7): 3036-47.

Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions., Sakata T, Anzai N, Shin HJ, Noshiro R, Hirata T, Yokoyama H, Kanai Y, Endou H., Biochem Biophys Res Commun. January 16, 2004; 313 (3): 789-93.

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1., Shu Y, Leabman MK, Feng B, Mangravite LM, Huang CC, Stryke D, Kawamoto M, Johns SJ, DeYoung J, Carlson E, Ferrin TE, Herskowitz I, Giacomini KM, Pharmacogenetics Of Membrane Transporters Investigators., Proc Natl Acad Sci U S A. May 13, 2003; 100 (10): 5902-7.        

Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences., Kerb R, Brinkmann U, Chatskaia N, Gorbunov D, Gorboulev V, Mornhinweg E, Keil A, Eichelbaum M, Koepsell H., Pharmacogenetics. November 1, 2002; 12 (8): 591-5.

The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP., Schlatter E, Mönnich V, Cetinkaya I, Mehrens T, Ciarimboli G, Hirsch JR, Popp C, Koepsell H., J Membr Biol. October 1, 2002; 189 (3): 237-44.

Functional characterization of mouse cation transporter mOCT2 compared with mOCT1., Kakehi M, Koyabu N, Nakamura T, Uchiumi T, Kuwano M, Ohtani H, Sawada Y., Biochem Biophys Res Commun. August 23, 2002; 296 (3): 644-50.        

Renal organic cation and nucleoside transport., Chen R, Jonker JW, Nelson JA., Biochem Pharmacol. July 15, 2002; 64 (2): 185-90.

Carriers involved in targeting the cytostatic bile acid-cisplatin derivatives cis-diammine-chloro-cholylglycinate-platinum(II) and cis-diammine-bisursodeoxycholate-platinum(II) toward liver cells., Briz O, Serrano MA, Rebollo N, Hagenbuch B, Meier PJ, Koepsell H, Marin JJ., Mol Pharmacol. April 1, 2002; 61 (4): 853-60.

Ventricular choline transport: a role for organic cation transporter 2 expressed in choroid plexus., Sweet DH, Miller DS, Pritchard JB., J Biol Chem. November 9, 2001; 276 (45): 41611-9.

Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct., Pavlova A, Sakurai H, Leclercq B, Beier DR, Yu AS, Nigam SK., Am J Physiol Renal Physiol. April 1, 2000; 278 (4): F635-43.

Kinetic and selectivity differences between rodent, rabbit, and human organic cation transporters (OCT1)., Dresser MJ, Gray AT, Giacomini KM., J Pharmacol Exp Ther. March 1, 2000; 292 (3): 1146-52.

Maximization of selenocysteine tRNA and U6 small nuclear RNA transcriptional activation achieved by flexible utilization of a Staf zinc finger., Schaub M, Myslinski E, Krol A, Carbon P., J Biol Chem. August 27, 1999; 274 (35): 25042-50.

Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain., Kusuhara H, Sekine T, Utsunomiya-Tate N, Tsuda M, Kojima R, Cha SH, Sugiyama Y, Kanai Y, Endou H., J Biol Chem. May 7, 1999; 274 (19): 13675-80.

Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes., Okuda M, Urakami Y, Saito H, Inui K., Biochim Biophys Acta. March 4, 1999; 1417 (2): 224-31.

The Oct-1 POU domain directs developmentally regulated nuclear translocation in Xenopus embryos., Veenstra GJ, Mathu MT, Destrée OH., Biol Chem. February 1, 1999; 380 (2): 253-7.

Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain., Wu X, Kekuda R, Huang W, Fei YJ, Leibach FH, Chen J, Conway SJ, Ganapathy V., J Biol Chem. December 4, 1998; 273 (49): 32776-86.

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