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Summary Expression Phenotypes Gene Literature (454) GO Terms (15) Nucleotides (103) Proteins (33) Interactants (2052) Wiki
XB-GENEPAGE-488038

Papers associated with shh



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49 ???displayGene.morpholinoPapers???

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Mechanical Tensions Regulate Gene Expression in the Xenopus laevis Axial Tissues., Eroshkin FM, Fefelova EA, Bredov DV, Orlov EE, Kolyupanova NM, Mazur AM, Sokolov AS, Zhigalova NA, Prokhortchouk EB, Nesterenko AM, Zaraisky AG., Int J Mol Sci. January 10, 2024; 25 (2):         


An archetype and scaling of developmental tissue dynamics across species., Morishita Y, Lee SW, Suzuki T, Yokoyama H, Kamei Y, Tamura K, Kawasumi-Kita A., Nat Commun. December 11, 2023; 14 (1): 8199.                              


Using Xenopus to discover new candidate genes involved in BOR and other congenital hearing loss syndromes., Neal SJ, Rajasekaran A, Jusić N, Taylor L, Read M, Alfandari D, Alfandari D, Pignoni F, Moody SA., J Exp Zool B Mol Dev Evol. October 13, 2023;             


Regenerative Potential of Injured Spinal Cord in the Light of Epigenetic Regulation and Modulation., Gupta S, Dutta S, Hui SP., Cells. June 22, 2023; 12 (13):       


Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling-dependent neurogenesis in the embryonic neural tube., Shim S, Goyal R, Panoutsopoulos AA, Balashova OA, Lee D, Borodinsky LN., Proc Natl Acad Sci U S A. June 6, 2023; 120 (23): e2220037120.


The shh limb enhancer is activated in patterned limb regeneration but not in hypomorphic limb regeneration in Xenopus laevis., Tada R, Higashidate T, Amano T, Ishikawa S, Yokoyama C, Kobari S, Nara S, Ishida K, Kawaguchi A, Ochi H, Ogino H, Yakushiji-Kaminatsui N, Sakamoto J, Kamei Y, Tamura K, Yokoyama H., Dev Biol. May 27, 2023; 500 22-30.                        


Inhibition of TRPP3 by calmodulin through Ca2+/calmodulin-dependent protein kinase II., Liu X, Wang Y, Weng Z, Xu Q, Zhou C, Tang J, Chen XZ., Cell Insight. April 1, 2023; 2 (2): 100088.              


Normal Table of Xenopus development: a new graphical resource., Zahn N, James-Zorn C, Ponferrada VG, Adams DS, Grzymkowski J, Buchholz DR, Nascone-Yoder NM, Horb M, Moody SA, Vize PD, Zorn AM., Development. July 15, 2022; 149 (14):                         


Essential roles of YAP-TEAD complex in adult stem cell development during thyroid hormone-induced intestinal remodeling of Xenopus laevis., Hasebe T, Fujimoto K, Ishizuya-Oka A., Cell Tissue Res. May 1, 2022; 388 (2): 313-329.


Cilia-localized GID/CTLH ubiquitin ligase complex regulates protein homeostasis of sonic hedgehog signaling components., Hantel F, Liu H, Fechtner L, Neuhaus H, Ding J, Arlt D, Walentek P, Villavicencio-Lorini P, Gerhardt C, Hollemann T, Pfirrmann T., J Cell Sci. May 1, 2022; 135 (9):                                     


Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development., Sun J, Yoon J, Lee M, Lee HK, Hwang YS, Daar IO., Cell Rep. February 1, 2022; 38 (5): 110312.                                          


Acute multidrug delivery via a wearable bioreactor facilitates long-term limb regeneration and functional recovery in adult Xenopus laevis., Murugan NJ, Vigran HJ, Miller KA, Golding A, Pham QL, Sperry MM, Rasmussen-Ivey C, Kane AW, Kaplan DL, Levin M., Sci Adv. January 28, 2022; 8 (4): eabj2164.            


Targeted search for scaling genes reveals matrixmetalloproteinase 3 as a scaler of the dorsal-ventral pattern in Xenopus laevis embryos., Orlov EE, Nesterenko AM, Korotkova DD, Parshina EA, Martynova NY, Zaraisky AG., Dev Cell. January 10, 2022; 57 (1): 95-111.e12.                                


Nodal asymmetry and hedgehog signaling during vertebrate left-right symmetry breaking., Negretti MI, Böse N, Petri N, Kremnyov S, Tsikolia N., Front Cell Dev Biol. January 1, 2022; 10 957211.  


Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development., Rankin SA, Rankin SA, Steimle JD, Yang XH, Rydeen AB, Agarwal K, Chaturvedi P, Ikegami K, Herriges MJ, Moskowitz IP, Zorn AM., Elife. October 13, 2021; 10


Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease., Getwan M, Hoppmann A, Schlosser P, Grand K, Song W, Diehl R, Schroda S, Heeg F, Deutsch K, Hildebrandt F, Lausch E, Köttgen A, Lienkamp SS., Proc Natl Acad Sci U S A. September 28, 2021; 118 (39):                                                   


Foxm1 regulates neural progenitor fate during spinal cord regeneration., Pelzer D, Phipps LS, Thuret R, Gallardo-Dodd CJ, Baker SM, Dorey K., EMBO Rep. September 6, 2021; 22 (9): e50932.                        


TGF-β1 signaling is essential for tissue regeneration in the Xenopus tadpole tail., Nakamura M, Yoshida H, Moriyama Y, Kawakita I, Wlizla M, Takebayashi-Suzuki K, Horb ME, Suzuki A., Biochem Biophys Res Commun. August 6, 2021; 565 91-96.          


Rab7 is required for mesoderm patterning and gastrulation in Xenopus., Kreis J, Wielath FM, Vick P., Biol Open. July 15, 2021; 10 (7):                                           


DLG5 variants are associated with multiple congenital anomalies including ciliopathy phenotypes., Marquez J, Mann N, Arana K, Deniz E, Ji W, Konstantino M, Mis EK, Deshpande C, Jeffries L, McGlynn J, Hugo H, Widmeier E, Konrad M, Tasic V, Morotti R, Baptista J, Ellard S, Lakhani SA, Hildebrandt F, Khokha MK., J Med Genet. July 1, 2021; 58 (7): 453-464.                        


Protocadherin-1 is expressed in the notochord of mouse embryo but is dispensable for its formation., Fukunaga K, Tanji M, Hanzawa N, Kuroda H, Inui M., Biochem Biophys Rep. June 15, 2021; 27 101047.          


Pinhead antagonizes Admp to promote notochord formation., Itoh K, Ossipova O, Sokol SY., iScience. May 7, 2021; 24 (6): 102520.                            


Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration in Xenopus laevis larvae., Hamilton AM, Balashova OA, Borodinsky LN., Elife. May 6, 2021; 10                               


A temporally resolved transcriptome for developing "Keller" explants of the Xenopus laevis dorsal marginal zone., Kakebeen AD, Huebner RJ, Shindo A, Kwon K, Kwon T, Wills AE, Wallingford JB., Dev Dyn. May 1, 2021; 250 (5): 717-731.              


Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience., Willsey HR, Exner CRT, Xu Y, Xu Y, Everitt A, Sun N, Wang B, Dea J, Schmunk G, Zaltsman Y, Teerikorpi N, Kim A, Anderson AS, Shin D, Seyler M, Nowakowski TJ, Harland RM, Willsey AJ, State MW., Neuron. March 3, 2021; 109 (5): 788-804.e8.


Thyroid Hormone Receptor Is Essential for Larval Epithelial Apoptosis and Adult Epithelial Stem Cell Development but Not Adult Intestinal Morphogenesis during Xenopus tropicalis Metamorphosis., Shibata Y, Tanizaki Y, Zhang H, Lee H, Dasso M, Shi YB, Shi YB., Cells. March 3, 2021; 10 (3):                             


Xenopus leads the way: Frogs as a pioneering model to understand the human brain., Exner CRT, Willsey HR., Genesis. February 1, 2021; 59 (1-2): e23405.          


Evolution of Somite Compartmentalization: A View From Xenopus., Della Gaspera B, Weill L, Chanoine C., Front Cell Dev Biol. January 1, 2021; 9 790847.                  


Thyroid hormone-induced expression of Foxl1 in subepithelial fibroblasts correlates with adult stem cell development during Xenopus intestinal remodeling., Hasebe T, Fujimoto K, Ishizuya-Oka A., Sci Rep. November 26, 2020; 10 (1): 20715.                


Amphibian thalamic nuclear organization during larval development and in the adult frog Xenopus laevis: Genoarchitecture and hodological analysis., Morona R, Bandín S, López JM, Moreno N, González A., J Comp Neurol. October 1, 2020; 528 (14): 2361-2403.                                                                


TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. September 14, 2020; 9                                                                                           


The critical role of dysregulated Hh-FOXM1-TPX2 signaling in human hepatocellular carcinoma cell proliferation., Wang Y, Wang H, Yan Z, Li G, Hu G, Zhang H, Huang D, Wang Y, Zhang X, Yan Y, Lu Q, Cheng M, Luo S., Cell Commun Signal. July 28, 2020; 18 (1): 116.              


A simple and practical workflow for genotyping of CRISPR-Cas9-based knockout phenotypes using multiplexed amplicon sequencing., Iida M, Suzuki M, Suzuki M, Sakane Y, Nishide H, Uchiyama I, Yamamoto T, Suzuki KT, Fujii S., Genes Cells. July 1, 2020; 25 (7): 498-509.                    


Model systems for regeneration: Xenopus., Phipps LS, Marshall L, Dorey K, Amaya E., Development. March 19, 2020; 147 (6):           


The AP-1 transcription factor JunB functions in Xenopus tail regeneration by positively regulating cell proliferation., Nakamura M, Yoshida H, Takahashi E, Wlizla M, Takebayashi-Suzuki K, Horb ME, Suzuki A., Biochem Biophys Res Commun. February 19, 2020; 522 (4): 990-995.              


Regeneration enhancers: Starting a journey to unravel regulatory events in tissue regeneration., Rodriguez AM, Kang J., Semin Cell Dev Biol. January 1, 2020;           


RA Signaling in Limb Development and Regeneration in Different Species., Maden M., Subcell Biochem. January 1, 2020; 95 87-117.


Isl1 Regulation of Nkx2.1 in the Early Foregut Epithelium Is Required for Trachea-Esophageal Separation and Lung Lobation., Kim E, Jiang M, Huang H, Zhang Y, Tjota N, Gao X, Robert J, Gilmore N, Gan L, Que J., Dev Cell. December 16, 2019; 51 (6): 675-683.e4.          


Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog-Gli Is Required for Tracheoesophageal Separation., Nasr T, Mancini P, Rankin SA, Rankin SA, Edwards NA, Agricola ZN, Kenny AP, Kinney JL, Daniels K, Vardanyan J, Han L, Trisno SL, Cha SW, Wells JM, Kofron MJ, Zorn AM., Dev Cell. December 16, 2019; 51 (6): 665-674.e6.                  


Cell type-specific transcriptome analysis unveils secreted signaling molecule genes expressed in apical epithelial cap during appendage regeneration., Okumura A, Hayashi T, Ebisawa M, Yoshimura M, Sasagawa Y, Nikaido I, Umesono Y, Mochii M., Dev Growth Differ. December 1, 2019; 61 (9): 447-456.                


Smoothened stimulation by membrane sterols drives Hedgehog pathway activity., Deshpande I, Liang J, Hedeen D, Roberts KJ, Zhang Y, Ha B, Latorraca NR, Faust B, Dror RO, Beachy PA, Myers BR, Manglik A., Nature. July 1, 2019; 571 (7764): 284-288.


Barhl2 maintains T cell factors as repressors and thereby switches off the Wnt/β-Catenin response driving Spemann organizer formation., Sena E, Rocques N, Borday C, Muhamad Amin HS, Parain K, Sitbon D, Chesneau A, Durand BC., Development. May 22, 2019; 146 (10):                                             


A dual function of FGF signaling in Xenopus left-right axis formation., Schneider I, Kreis J, Schweickert A, Blum M, Vick P., Development. May 10, 2019; 146 (9):                               


Transcriptome profiling reveals male- and female-specific gene expression pattern and novel gene candidates for the control of sex determination and gonad development in Xenopus laevis., Piprek RP, Damulewicz M, Tassan JP, Kloc M, Kubiak JZ., Dev Genes Evol. May 1, 2019; 229 (2-3): 53-72.        


Stereoselective fatty acylation is essential for the release of lipidated WNT proteins from the acyltransferase Porcupine (PORCN)., Tuladhar R, Yarravarapu N, Ma Y, Zhang C, Herbert J, Kim J, Chen C, Lum L., J Biol Chem. April 19, 2019; 294 (16): 6273-6282.              


Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway., Neitzel LR, Spencer ZT, Nayak A, Cselenyi CS, Benchabane H, Youngblood CQ, Zouaoui A, Ng V, Stephens L, Hann T, Patton JG, Robbins D, Ahmed Y, Lee E., Mech Dev. April 1, 2019; 156 20-31.                              


Xenopus slc7a5 is essential for notochord function and eye development., Katada T, Sakurai H., Mech Dev. February 1, 2019; 155 48-59.                


More Than Just a Bandage: Closing the Gap Between Injury and Appendage Regeneration., Kakebeen AD, Wills AE., Front Physiol. January 1, 2019; 10 81.      


Gli2 is required for the induction and migration of Xenopus laevis neural crest., Cerrizuela S, Vega-López GA, Palacio MB, Tríbulo C, Aybar MJ, Aybar MJ., Mech Dev. December 1, 2018; 154 219-239.                      


WDR5 regulates left-right patterning via chromatin-dependent and -independent functions., Kulkarni SS, Khokha MK., Development. November 28, 2018; 145 (23):                 

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