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Summary Expression Phenotypes Gene Literature (65) GO Terms (0) Nucleotides (60) Proteins (37) Interactants (75) Wiki
XB-GENEPAGE-950264

Papers associated with hcn1



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Pore-to-gate coupling of HCN channels revealed by a pore variant that contributes to gating but not permeation., Azene EM, Sang D, Tsang SY, Li RA., Biochem Biophys Res Commun. February 25, 2005; 327 (4): 1131-42.

Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channels., Craven KB, Zagotta WN., J Gen Physiol. December 1, 2004; 124 (6): 663-77.                      

Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction., Santoro B, Wainger BJ, Siegelbaum SA., J Neurosci. November 24, 2004; 24 (47): 10750-62.

Critical intra-linker interactions of HCN1-encoded pacemaker channels revealed by interchange of S3-S4 determinants., Tsang SY, Lesso H, Li RA., Biochem Biophys Res Commun. September 17, 2004; 322 (2): 652-8.

Changes in local S4 environment provide a voltage-sensing mechanism for mammalian hyperpolarization-activated HCN channels., Bell DC, Yao H, Saenger RC, Riley JH, Siegelbaum SA., J Gen Physiol. January 1, 2004; 123 (1): 5-19.            

S4 movement in a mammalian HCN channel., Vemana S, Pandey S, Larsson HP., J Gen Physiol. January 1, 2004; 123 (1): 21-32.                

Tyrosine kinase inhibition differentially regulates heterologously expressed HCN channels., Yu HG, Lu Z, Pan Z, Cohen IS., Pflugers Arch. January 1, 2004; 447 (4): 392-400.

KCNE2 modulates current amplitudes and activation kinetics of HCN4: influence of KCNE family members on HCN4 currents., Decher N, Bundis F, Vajna R, Steinmeyer K., Pflugers Arch. September 1, 2003; 446 (6): 633-40.

Identification of a surface charged residue in the S3-S4 linker of the pacemaker (HCN) channel that influences activation gating., Henrikson CA, Xue T, Dong P, Sang D, Marban E, Li RA., J Biol Chem. April 18, 2003; 278 (16): 13647-54.

Molecular basis of the effect of potassium on heterologously expressed pacemaker (HCN) channels., Azene EM, Xue T, Li RA., J Physiol. March 1, 2003; 547 (Pt 2): 349-56.

Dominant-negative suppression of HCN1- and HCN2-encoded pacemaker currents by an engineered HCN1 construct: insights into structure-function relationships and multimerization., Xue T, Marbán E, Li RA., Circ Res. June 28, 2002; 90 (12): 1267-73.

Gi- and Gs-coupled receptors up-regulate the cAMP cascade to modulate HCN2, but not HCN1 pacemaker channels., Ulens C, Tytgat J., Pflugers Arch. September 1, 2001; 442 (6): 928-42.

Regulation of hyperpolarization-activated HCN channel gating and cAMP modulation due to interactions of COOH terminus and core transmembrane regions., Wang J, Chen S, Siegelbaum SA., J Gen Physiol. September 1, 2001; 118 (3): 237-50.              

Properties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotide., Chen S, Wang J, Siegelbaum SA., J Gen Physiol. May 1, 2001; 117 (5): 491-504.                  

Functional heteromerization of HCN1 and HCN2 pacemaker channels., Ulens C, Tytgat J., J Biol Chem. March 2, 2001; 276 (9): 6069-72.

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