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Conformationally sensitive proximity of extracellular loops 2 and 4 of the γ-aminobutyric acid (GABA) transporter GAT-1 inferred from paired cysteine mutagenesis. , Hilwi M, Dayan O, Kanner BI., J Biol Chem. December 5, 2014; 289 (49): 34258-66.
The aromatic and charge pairs of the thin extracellular gate of the γ-aminobutyric acid transporter GAT-1 are differently impacted by mutation. , Dayan O, Ben-Yona A, Kanner BI., J Biol Chem. October 10, 2014; 289 (41): 28172-8.
Functional defects in the external and internal thin gates of the γ-aminobutyric acid (GABA) transporter GAT-1 can compensate each other. , Ben-Yona A, Kanner BI., J Biol Chem. February 15, 2013; 288 (7): 4549-56.
An acidic amino acid transmembrane helix 10 residue conserved in the neurotransmitter:sodium:symporters is essential for the formation of the extracellular gate of the γ-aminobutyric acid (GABA) transporter GAT-1. , Ben-Yona A, Kanner BI., J Biol Chem. March 2, 2012; 287 (10): 7159-68.
A glutamine residue conserved in the neurotransmitter:sodium:symporters is essential for the interaction of chloride with the GABA transporter GAT-1. , Ben-Yona A, Bendahan A, Kanner BI., J Biol Chem. January 28, 2011; 286 (4): 2826-33.
Elucidating conformational changes in the gamma-aminobutyric acid transporter-1. , Meinild AK, Loo DDF, Skovstrup S, Gether U, MacAulay N., J Biol Chem. June 12, 2009; 284 (24): 16226-16235.
The role of early lineage in GABAergic and glutamatergic cell fate determination in Xenopus laevis. , Li M, Sipe CW, Hoke K, August LL, Wright MA, Saha MS ., J Comp Neurol. April 20, 2006; 495 (6): 645-57.
Transporter-associated currents in the gamma-aminobutyric acid transporter GAT-1 are conditionally impaired by mutations of a conserved glycine residue. , Zhou Y, Kanner BI., J Biol Chem. May 27, 2005; 280 (21): 20316-24.
A Na+/Cl- -coupled GABA transporter, GAT-1, from Caenorhabditis elegans: structural and functional features, specific expression in GABA-ergic neurons, and involvement in muscle function. , Jiang G, Zhuang L, Miyauchi S, Miyake K, Fei YJ, Ganapathy V., J Biol Chem. January 21, 2005; 280 (3): 2065-77.
Cloning, immunolocalization, and functional expression of a GABA transporter from the retina of the skate. , Birnbaum AD, Rohde SK, Qian H, Al-Ubaidi MR, Caldwell JH, Malchow RP., Vis Neurosci. January 1, 2005; 22 (2): 211-23.
The interaction of the gamma-aminobutyric acid transporter GAT-1 with the neurotransmitter is selectively impaired by sulfhydryl modification of a conformationally sensitive cysteine residue engineered into extracellular loop IV. , Zomot E, Kanner BI., J Biol Chem. October 31, 2003; 278 (44): 42950-8.
Residues in the extracellular loop 4 are critical for maintaining the conformational equilibrium of the gamma-aminobutyric acid transporter-1. , MacAulay N, Meinild AK, Zeuthen T, Gether U., J Biol Chem. August 1, 2003; 278 (31): 28771-7.
Transmembrane domain I of the gamma-aminobutyric acid transporter GAT-1 plays a crucial role in the transition between cation leak and transport modes. , Kanner BI., J Biol Chem. February 7, 2003; 278 (6): 3705-12.
Conformational basis for the Li(+)-induced leak current in the rat gamma-aminobutyric acid (GABA) transporter-1. , MacAulay N, Zeuthen T, Gether U., J Physiol. October 15, 2002; 544 (2): 447-58.
An intermediate state of the gamma-aminobutyric acid transporter GAT1 revealed by simultaneous voltage clamp and fluorescence. , Li M, Farley RA, Lester HA., J Gen Physiol. April 1, 2000; 115 (4): 491-508.
Analysis of the transmembrane topology and membrane assembly of the GAT-1 gamma-aminobutyric acid transporter. , Clark JA., J Biol Chem. June 6, 1997; 272 (23): 14695-704.
Efflux of gamma-aminobutyric acid caused by changes in ion concentrations and cell swelling simulating the effect of cerebral ischaemia. , Haugstad TS, Karlsen HE, Krajtci P, Due-Tønnessen B, Larsen M, Sandberg C, Sand O, Brandtzaeg P, Langmoen IA., Acta Neurochir (Wien). January 1, 1997; 139 (5): 453-63.
Cloning, expression, and localization of a mouse retinal gamma-aminobutyric acid transporter. , Ruiz M, Egal H, Sarthy V, Qian X, Sarkar HK., Invest Ophthalmol Vis Sci. November 1, 1994; 35 (12): 4039-48.
The neuronal and epithelial human high affinity glutamate transporter. Insights into structure and mechanism of transport. , Kanai Y, Stelzner M, Nussberger S, Khawaja S, Hebert SC, Smith CP, Hediger MA., J Biol Chem. August 12, 1994; 269 (32): 20599-606.
Glia of the cholinergic electromotor nucleus of Torpedo are the source of the cDNA encoding a GAT-1-like GABA transporter. , Swanson GT, Umbach JA , Gundersen CB ., J Neurochem. July 1, 1994; 63 (1): 1-12.
Electrogenic uptake of gamma-aminobutyric acid by a cloned transporter expressed in Xenopus oocytes. , Kavanaugh MP, Arriza JL, North RA, Amara SG., J Biol Chem. November 5, 1992; 267 (31): 22007-9.
Expression of a cloned gamma-aminobutyric acid transporter in mammalian cells. , Keynan S, Suh YJ, Kanner BI, Rudnick G., Biochemistry. February 25, 1992; 31 (7): 1974-9.
Cloning and expression of a rat brain GABA transporter. , Guastella J, Nelson N, Nelson H, Czyzyk L, Keynan S, Miedel MC, Davidson N, Lester HA, Kanner BI., Science. September 14, 1990; 249 (4974): 1303-6.