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Summary Expression Phenotypes Gene Literature (226) GO Terms (6) Nucleotides (305) Proteins (73) Interactants (445) Wiki
XB-GENEPAGE-921634

Papers associated with gnao1



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Protriptyline block of the human ether-à-go-go-related gene (HERG) K+ channel., Jo SH, Hong HK, Chong SH, Choe H., Life Sci. January 30, 2008; 82 (5-6): 331-40.

Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator., Perry M, Sachse FB, Sanguinetti MC., Proc Natl Acad Sci U S A. August 21, 2007; 104 (34): 13827-32.

Messages in the matrix: proteoglycans go the distance., Gallagher J., Dev Cell. August 1, 2007; 13 (2): 166-7.

Molecular interaction of droperidol with human ether-a-go-go-related gene channels: prolongation of action potential duration without inducing early afterdepolarization., Schwoerer AP, Blütner C, Brandt S, Binder S, Siebrands CC, Ehmke H, Friederich P., Anesthesiology. May 1, 2007; 106 (5): 967-76.

Maprotiline block of the human ether-a-go-go-related gene (HERG) K+ channel., Jo SH, Hong HK, Jung SJ, Chong SH, Yun JH, Koh YS, Choe H., Arch Pharm Res. April 1, 2007; 30 (4): 453-60.

Pairing morphology with gene expression in thyroid hormone-induced intestinal remodeling and identification of a core set of TH-induced genes across tadpole tissues., Buchholz DR, Heimeier RA, Das B, Washington T, Shi YB., Dev Biol. March 15, 2007; 303 (2): 576-90.

Structural requirements of human ether-a-go-go-related gene channels for block by bupivacaine., Siebrands CC, Friederich P., Anesthesiology. March 1, 2007; 106 (3): 523-31.

Differences between ion binding to eag and HERG voltage sensors contribute to differential regulation of activation and deactivation gating., Lin MC, Papazian DM., Channels (Austin). January 1, 2007; 1 (6): 429-37.

In vitro modulation of HERG channels by organochlorine solvent trichlormethane as potential explanation for proarrhythmic effects of chloroform., Scholz EP, Alter M, Zitron E, Kiesecker C, Kathöfer S, Thomas D, Kreye VA, Kreuzer J, Becker R, Katus HA, Greten J, Karle CA., Toxicol Lett. August 20, 2006; 165 (2): 156-66.

Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine., Lee SY, Kim YJ, Kim KT, Choe H, Jo SH., Br J Pharmacol. June 1, 2006; 148 (4): 499-509.

The D3-dopaminergic agonist 7-hydroxy-dipropylaminotetralin (7-OH-DPAT) increases cardiac action potential duration and blocks human ether-a-go-go-related gene K+ channel., Torres-Jácome J, Tejeda-Chávez HR, Rodríguez-Menchaca AA, Sánchez-Chapula JA, Navarro-Polanco RA., J Cardiovasc Pharmacol. May 1, 2006; 47 (5): 656-62.

Chemical modification of the human ether-a-go-go-related gene (HERG) K+ current by the amino-group reagent trinitrobenzene sulfonic acid., Jo SH, Choi SY, Yun JH, Koh YS, Ho WK, Lee CO, Lee CO., Arch Pharm Res. April 1, 2006; 29 (4): 310-7.

Mechanism of action of a novel human ether-a-go-go-related gene channel activator., Casis O, Olesen SP, Sanguinetti MC., Mol Pharmacol. February 1, 2006; 69 (2): 658-65.

The effects of sevoflurane and propofol on QT interval and heterologously expressed human ether-a-go-go related gene currents in Xenopus oocytes., Yamada M, Hatakeyama N, Malykhina AP, Yamazaki M, Momose Y, Akbarali HI., Anesth Analg. January 1, 2006; 102 (1): 98-103.

Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643)., Hansen RS, Diness TG, Christ T, Demnitz J, Ravens U, Olesen SP, Grunnet M., Mol Pharmacol. January 1, 2006; 69 (1): 266-77.

Expression and functional characterization of the human ether-à-go-go-related gene (HERG) K+ channel cardiac splice variant in Xenopus laevis oocytes., Aydar E, Palmer C., J Membr Biol. January 1, 2006; 211 (2): 115-26.

Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor., Bannister JP, Chanda B, Bezanilla F, Papazian DM., Proc Natl Acad Sci U S A. December 20, 2005; 102 (51): 18718-23.

Inhibitory effect of rhynchophylline on human ether-a-go-go related gene channel., Gui L, Li ZW, Du R, Yuan GH, Li W, Ren FX, Li J, Yang JG., Sheng Li Xue Bao. October 25, 2005; 57 (5): 648-52.

Molecular mapping of a site for Cd2+-induced modification of human ether-à-go-go-related gene (hERG) channel activation., Fernandez D, Ghanta A, Kinard KI, Sanguinetti MC., J Physiol. September 15, 2005; 567 (Pt 3): 737-55.

K channel subconductance levels result from heteromeric pore conformations., Chapman ML, VanDongen AM., J Gen Physiol. August 1, 2005; 126 (2): 87-103.                                

Go G-proteins mediate rapid heterologous desensitization of G-protein coupled receptors in Xenopus oocytes., Van-Ham II, Oron Y., J Cell Physiol. August 1, 2005; 204 (2): 455-62.

Camguk/CASK enhances Ether-á-go-go potassium current by a phosphorylation-dependent mechanism., Marble DD, Hegle AP, Snyder ED, Dimitratos S, Bryant PJ, Wilson GF., J Neurosci. May 18, 2005; 25 (20): 4898-907.

Inhibition of human ether-a-go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine., Choi SY, Koh YS, Jo SH., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.

Modulating effect of ginseng saponins on heterologously expressed HERG currents in Xenopus oocytes., Kim CS, Son SJ, Kim HS, Kim YD, Lee KS, Jeon BH, Kim KJ, Park JK, Park JB., Acta Pharmacol Sin. May 1, 2005; 26 (5): 551-8.

p90Rsk is not involved in cytostatic factor arrest in mouse oocytes., Dumont J, Umbhauer M, Rassinier P, Hanauer A, Verlhac MH., J Cell Biol. April 25, 2005; 169 (2): 227-31.        

XenDB: full length cDNA prediction and cross species mapping in Xenopus laevis., Sczyrba A, Beckstette M, Brivanlou AH, Giegerich R, Altmann CR., BMC Genomics. April 1, 2005; 6 123.          

An atlas of differential gene expression during early Xenopus embryogenesis., Pollet N, Muncke N, Verbeek B, Li Y, Fenger U, Delius H, Niehrs C., Mech Dev. March 1, 2005; 122 (3): 365-439.                                                                                                                                                        

Effect of beta-adrenoceptor blockers on human ether-a-go-go-related gene (HERG) potassium channels., Dupuis DS, Klaerke DA, Olesen SP., Basic Clin Pharmacol Toxicol. February 1, 2005; 96 (2): 123-30.

A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a-go-go-related gene (HERG) channels., Lin C, Cvetanovic I, Ke X, Ranade V, Somberg J., Am J Ther. January 1, 2005; 12 (4): 328-36.

Functional roles of nonconserved structural segments in CFTR's NH2-terminal nucleotide binding domain., Csanády L, Chan KW, Nairn AC, Gadsby DC., J Gen Physiol. January 1, 2005; 125 (1): 43-55.              

Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channels., Craven KB, Zagotta WN., J Gen Physiol. December 1, 2004; 124 (6): 663-77.                      

Block of wild-type and inactivation-deficient human ether-a-go-go-related gene K+ channels by halofantrine., Sánchez-Chapula JA, Navarro-Polanco RA, Sanguinetti MC., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 484-91.

Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by alpha(1A)-adrenoceptors., Thomas D, Wu K, Wimmer AB, Zitron E, Hammerling BC, Kathöfer S, Lueck S, Bloehs R, Kreye VA, Kiehn J, Katus HA, Schoels W, Karle CA., J Mol Med (Berl). December 1, 2004; 82 (12): 826-37.

Binding site in eag voltage sensor accommodates a variety of ions and is accessible in closed channel., Silverman WR, Bannister JP, Papazian DM., Biophys J. November 1, 2004; 87 (5): 3110-21.

Intracellular actin-based transport: how far you go depends on how often you switch., Snider J, Lin F, Zahedi N, Rodionov V, Yu CC, Gross SP., Proc Natl Acad Sci U S A. September 7, 2004; 101 (36): 13204-9.

Molecular basis of slow activation of the human ether-a-go-go related gene potassium channel., Subbiah RN, Clarke CE, Smith DJ, Zhao J, Campbell TJ, Vandenberg JI., J Physiol. July 15, 2004; 558 (Pt 2): 417-31.

Response to lysophosphatidic acid in Xenopus oocytes and its rapid desensitization: the role of Gq and Go G-protein families., Van-Ham II, Lupu-Meiri M, Tayer M, Shapira H, Oron Y., J Cell Physiol. July 1, 2004; 200 (1): 125-33.

Comparison of kinetic properties of quinidine and dofetilide block of HERG channels., Tsujimae K, Suzuki S, Yamada M, Kurachi Y., Eur J Pharmacol. June 16, 2004; 493 (1-3): 29-40.

Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels., Dong DL, Li Z, Wang HZ, Du ZM, Song WH, Yang BF., Basic Clin Pharmacol Toxicol. May 1, 2004; 94 (5): 209-12.

Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin., Thomas D, Wimmer AB, Wu K, Hammerling BC, Ficker EK, Kuryshev YA, Kiehn J, Katus HA, Schoels W, Karle CA., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2004; 369 (5): 462-72.

G protein-activated K+ channels: a reporter for rapid activation of G proteins by lysophosphatidic acid in Xenopus oocytes., Itzhaki Van-Ham I, Peleg S, Dascal N, Shapira H, Oron Y., FEBS Lett. April 23, 2004; 564 (1-2): 157-60.

GoSurfer: a graphical interactive tool for comparative analysis of large gene sets in Gene Ontology space., Zhong S, Storch KF, Lipan O, Kao MC, Weitz CJ, Wong WH., Appl Bioinformatics. January 1, 2004; 3 (4): 261-4.

Gating currents associated with intramembrane charge displacement in HERG potassium channels., Piper DR, Varghese A, Sanguinetti MC, Tristani-Firouzi M., Proc Natl Acad Sci U S A. September 2, 2003; 100 (18): 10534-9.

Voltage-dependent profile of human ether-a-go-go-related gene channel block is influenced by a single residue in the S6 transmembrane domain., Sănchez-Chapula JA, Ferrer T, Navarro-Polanco RA, Sanguinetti MC., Mol Pharmacol. May 1, 2003; 63 (5): 1051-8.

BeKm-1 is a HERG-specific toxin that shares the structure with ChTx but the mechanism of action with ErgTx1., Zhang M, Korolkova YV, Liu J, Jiang M, Grishin EV, Tseng GN., Biophys J. May 1, 2003; 84 (5): 3022-36.

Molecular characterization, functional expression, and developmental profile of an ether à-go-go K+ channel in the tobacco hornworm Manduca sexta., Keyser MR, Anson BD, Titus SA, Ganetzky B, Witten JL., J Neurobiol. April 1, 2003; 55 (1): 73-85.

Structural basis of two-stage voltage-dependent activation in K+ channels., Silverman WR, Roux B, Papazian DM., Proc Natl Acad Sci U S A. March 4, 2003; 100 (5): 2935-40.

Cloning and functional characterization of the smooth muscle ether-a-go-go-related gene K+ channel. Potential role of a conserved amino acid substitution in the S4 region., Shoeb F, Malykhina AP, Akbarali HI., J Biol Chem. January 24, 2003; 278 (4): 2503-14.

Interaction with GM130 during HERG ion channel trafficking. Disruption by type 2 congenital long QT syndrome mutations. Human Ether-à-go-go-Related Gene., Roti EC, Myers CD, Ayers RA, Boatman DE, Delfosse SA, Chan EK, Ackerman MJ, January CT, Robertson GA., J Biol Chem. December 6, 2002; 277 (49): 47779-85.

KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current., Angelo K, Jespersen T, Grunnet M, Nielsen MS, Klaerke DA, Olesen SP., Biophys J. October 1, 2002; 83 (4): 1997-2006.

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