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Summary Expression Phenotypes Gene Literature (168) GO Terms (13) Nucleotides (51) Proteins (32) Interactants (654) Wiki
XB-GENEPAGE-866804

Papers associated with slc12a3



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The structure and development of Xenopus laevis cornea., Hu W, Haamedi N, Lee J, Kinoshita T, Ohnuma S., Exp Eye Res. November 1, 2013; 116 109-28.                            


Protein tyrosine phosphatase 4A3 (PTP4A3) is required for Xenopus laevis cranial neural crest migration in vivo., Maacha S, Planque N, Laurent C, Pegoraro C, Anezo O, Maczkowiak F, Monsoro-Burq AH, Saule S., PLoS One. December 9, 2013; 8 (12): e84717.              


Regulation of NKCC2 activity by inhibitory SPAK isoforms: KS-SPAK is a more potent inhibitor than SPAK2., Park HJ, Curry JN, McCormick JA., Am J Physiol Renal Physiol. December 15, 2013; 305 (12): F1687-96.


SPAK and OSR1 dependent down-regulation of murine renal outer medullary K channel ROMK1., Elvira B, Munoz C, Borras J, Chen H, Warsi J, Ajay SS, Shumilina E, Lang F., Kidney Blood Press Res. January 1, 2014; 39 (4): 353-60.


A novel N-terminal motif is responsible for the evolution of neural crest-specific gene-regulatory activity in vertebrate FoxD3., Ono H, Kozmik Z, Yu JK, Wada H., Dev Biol. January 15, 2014; 385 (2): 396-404.    


Protein phosphatase 1 inhibitor-1 deficiency reduces phosphorylation of renal NaCl cotransporter and causes arterial hypotension., Picard N, Trompf K, Yang CL, Miller RL, Carrel M, Loffing-Cueni D, Fenton RA, Ellison DH, Loffing J., J Am Soc Nephrol. March 1, 2014; 25 (3): 511-22.


MicroRNAs are critical regulators of tuberous sclerosis complex and mTORC1 activity in the size control of the Xenopus kidney., Romaker D, Kumar V, Cerqueira DM, Cox RM, Wessely O., Proc Natl Acad Sci U S A. April 29, 2014; 111 (17): 6335-40.                                                          


Six1 is a key regulator of the developmental and evolutionary architecture of sensory neurons in craniates., Yajima H, Suzuki M, Ochi H, Ikeda K, Sato S, Yamamura K, Ogino H, Ueno N, Kawakami K., BMC Biol. May 29, 2014; 12 40.                        


WNK3 abrogates the NEDD4-2-mediated inhibition of the renal Na+-Cl- cotransporter., Lagnaz D, Arroyo JP, Chávez-Canales M, Vázquez N, Rizzo F, Spirlí A, Debonneville A, Staub O, Gamba G., Am J Physiol Renal Physiol. August 1, 2014; 307 (3): F275-86.


Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts., Cerqueira DM, Tran U, Romaker D, Abreu JG, Wessely O., Dev Biol. October 1, 2014; 394 (1): 54-64.                                          


WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4., Chávez-Canales M, Zhang C, Soukaseum C, Moreno E, Pacheco-Alvarez D, Vidal-Petiot E, Castañeda-Bueno M, Vázquez N, Rojas-Vega L, Meermeier NP, Rogers S, Jeunemaitre X, Yang CL, Ellison DH, Gamba G, Hadchouel J., Hypertension. November 1, 2014; 64 (5): 1047-53.


Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3., McCormick JA, Yang CL, Zhang C, Davidge B, Blankenstein KI, Terker AS, Yarbrough B, Meermeier NP, Park HJ, McCully B, West M, Borschewski A, Himmerkus N, Bleich M, Bachmann S, Mutig K, Argaiz ER, Gamba G, Singer JD, Ellison DH., J Clin Invest. November 1, 2014; 124 (11): 4723-36.


TACC3 is a microtubule plus end-tracking protein that promotes axon elongation and also regulates microtubule plus end dynamics in multiple embryonic cell types., Nwagbara BU, Faris AE, Bearce EA, Erdogan B, Ebbert PT, Evans MF, Rutherford EL, Enzenbacher TB, Lowery LA., Mol Biol Cell. November 1, 2014; 25 (21): 3350-62.                              


Regulation of HbPIP2;3, a Latex-Abundant Water Transporter, Is Associated with Latex Dilution and Yield in the Rubber Tree (Hevea brasiliensis Muell. Arg.)., An F, Zou Z, Cai X, Wang J, Rookes J, Lin W, Cahill D, Kong L., PLoS One. January 1, 2015; 10 (4): e0125595.                    


The emergence of Pax7-expressing muscle stem cells during vertebrate head muscle development., Nogueira JM, Hawrot K, Sharpe C, Noble A, Wood WM, Jorge EC, Goldhamer DJ, Kardon G, Dietrich S., Front Aging Neurosci. May 19, 2015; 7 62.                                            


Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells., Aoto K, Sandell LL, Butler Tjaden NE, Yuen KC, Watt KE, Black BL, Durnin M, Trainor PA., Dev Biol. June 1, 2015; 402 (1): 3-16.


The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride., Bazúa-Valenti S, Chávez-Canales M, Rojas-Vega L, González-Rodríguez X, Vázquez N, Rodríguez-Gama A, Argaiz ER, Melo Z, Plata C, Ellison DH, García-Valdés J, Hadchouel J, Gamba G., J Am Soc Nephrol. August 1, 2015; 26 (8): 1781-6.


WNK3 Kinase Enhances the Sodium Chloride Cotransporter Expression via an ERK 1/2 Signaling Pathway., Wang D, Zhang Y, Han J, Pan S, Xu N, Feng X, Zhuang Z, Caroti C, Zhuang J, Hoover RS, Gu D, Zeng Q, Cai H., Nephron. January 1, 2016; 133 (4): 287-95.


Platelet derived growth factor B gene expression in the Xenopus laevis developing central nervous system., Giannetti K, Corsinovi D, Rossino C, Appolloni I, Malatesta P, Ori M., Int J Dev Biol. January 1, 2016; 60 (4-6): 175-9.      


Alternative splice variant of the thiazide-sensitive NaCl cotransporter: a novel player in renal salt handling., Tutakhel OA, Jeleń S, Valdez-Flores M, Dimke H, Piersma SR, Jimenez CR, Deinum J, Lenders JW, Hoenderop JG, Bindels RJ., Am J Physiol Renal Physiol. February 1, 2016; 310 (3): F204-16.


Hmga2 is required for neural crest cell specification in Xenopus laevis., Macrì S, Simula L, Pellarin I, Pegoraro S, Onorati M, Sgarra R, Manfioletti G, Vignali R., Dev Biol. March 1, 2016; 411 (1): 25-37.                                        


Cadherin-11 localizes to focal adhesions and promotes cell-substrate adhesion., Langhe RP, Gudzenko T, Bachmann M, Becker SF, Gonnermann C, Winter C, Abbruzzese G, Alfandari D, Alfandari D, Kratzer MC, Franz CM, Kashef J., Nat Commun. March 8, 2016; 7 10909.        


In vivo confinement promotes collective migration of neural crest cells., Szabó A, Melchionda M, Nastasi G, Woods ML, Campo S, Perris R, Mayor R., J Cell Biol. June 6, 2016; 213 (5): 543-55.                


With no lysine L-WNK1 isoforms are negative regulators of the K+-Cl- cotransporters., Mercado A, de Los Heros P, Melo Z, Chávez-Canales M, Murillo-de-Ozores AR, Moreno E, Bazúa-Valenti S, Vázquez N, Hadchouel J, Gamba G., Am J Physiol Cell Physiol. July 1, 2016; 311 (1): C54-66.


ROMK expression remains unaltered in a mouse model of familial hyperkalemic hypertension caused by the CUL3Δ403-459 mutation., Murthy M, Kurz T, O'Shaughnessy KM., Physiol Rep. July 1, 2016; 4 (13):             


Embryonic expression of endothelins and their receptors in lamprey and frog reveals stem vertebrate origins of complex Endothelin signaling., Square T, Jandzik D, Cattell M, Hansen A, Medeiros DM., Sci Rep. September 28, 2016; 6 34282.                          


Chlorpyrifos exposure affects fgf8, sox9, and bmp4 expression required for cranial neural crest morphogenesis and chondrogenesis in Xenopus laevis embryos., Tussellino M, Ronca R, Carotenuto R, Pallotta MM, Furia M, Capriglione T., Environ Mol Mutagen. October 1, 2016; 57 (8): 630-640.


The European Eel NCCβ Gene Encodes a Thiazide-resistant Na-Cl Cotransporter., Moreno E, Plata C, Rodríguez-Gama A, Argaiz ER, Vázquez N, Leyva-Ríos K, Islas L, Cutler C, Pacheco-Alvarez D, Mercado A, Cariño-Cortés R, Castañeda-Bueno M, Gamba G., J Biol Chem. October 21, 2016; 291 (43): 22472-22481.


Functional aspects of early brain development are preserved in tuberous sclerosis complex (TSC) epileptogenic lesions., Ruffolo G, Iyer A, Cifelli P, Roseti C, Mühlebner A, van Scheppingen J, Scholl T, Hainfellner JA, Feucht M, Krsek P, Zamecnik J, Jansen FE, Spliet WG, Limatola C, Aronica E, Palma E., Neurobiol Dis. November 1, 2016; 95 93-101.


Functionomics of NCC mutations in Gitelman syndrome using a novel mammalian cell-based activity assay., Valdez-Flores MA, Vargas-Poussou R, Verkaart S, Tutakhel OA, Valdez-Ortiz A, Blanchard A, Treard C, Hoenderop JG, Bindels RJ, Jeleń S., Am J Physiol Renal Physiol. December 1, 2016; 311 (6): F1159-F1167.


Implication of thyroid hormone signaling in neural crest cells migration: Evidence from thyroid hormone receptor beta knockdown and NH3 antagonist studies., Bronchain OJ, Chesneau A, Monsoro-Burq AH, Jolivet P, Paillard E, Scanlan TS, Demeneix BA, Sachs LM, Pollet N., Mol Cell Endocrinol. January 5, 2017; 439 233-246.


Renal localization and regulation by dietary phosphate of the MCT14 orphan transporter., Knöpfel T, Atanassoff A, Hernando N, Biber J, Wagner CA., PLoS One. June 29, 2017; 12 (6): e0177942.          


Functional assessment of sodium chloride cotransporter NCC mutants in polarized mammalian epithelial cells., Rosenbaek LL, Rizzo F, MacAulay N, Staub O, Fenton RA., Am J Physiol Renal Physiol. August 1, 2017; 313 (2): F495-F504.


PFKFB4 control of AKT signaling is essential for premigratory and migratory neural crest formation., Figueiredo AL, Maczkowiak F, Borday C, Pla P, Sittewelle M, Pegoraro C, Monsoro-Burq AH., Development. November 15, 2017; 144 (22): 4183-4194.                                


Cadherin-11 promotes neural crest cell spreading by reducing intracellular tension-Mapping adhesion and mechanics in neural crest explants by atomic force microscopy., Blaue C, Kashef J, Franz CM., Semin Cell Dev Biol. January 1, 2018; 73 95-106.                    


Geraniin is a diuretic by inhibiting the Na+-K+-2Cl- cotransporter NKCC2., Moreno E, Gayosso JA, Montejano JR, Almaguer G, Vázquez N, Cruz C, Mercado A, Bobadilla NA, Gamba G, Sierra A, Ramírez V., Am J Physiol Renal Physiol. February 1, 2018; 314 (2): F240-F250.


Regulation of c-MYC transcriptional activity by transforming growth factor-beta 1-stimulated clone 22., Zheng L, Suzuki H, Nakajo Y, Nakano A, Kato M., Cancer Sci. February 1, 2018; 109 (2): 395-402.


Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney., Zhang B, Tran U, Wessely O., Development. March 22, 2018; 145 (6):                         


Expression of the adhesion G protein-coupled receptor A2 (adgra2) during Xenopus laevis development., Seigfried FA, Dietmann P, Kühl M, Kühl SJ., Gene Expr Patterns. June 1, 2018; 28 54-61.                                      


The Calcium-Sensing Receptor Increases Activity of the Renal NCC through the WNK4-SPAK Pathway., Bazúa-Valenti S, Rojas-Vega L, Castañeda-Bueno M, Barrera-Chimal J, Bautista R, Cervantes-Pérez LG, Vázquez N, Plata C, Murillo-de-Ozores AR, González-Mariscal L, Ellison DH, Riccardi D, Bobadilla NA, Gamba G., J Am Soc Nephrol. July 1, 2018; 29 (7): 1838-1848.


Gitelman's Syndrome: characterization of a novel c.1181G>A point mutation and functional classification of the known mutations., Ravarotto V, Loffing J, Loffing-Cueni D, Heidemeyer M, Pagnin E, Calò LA, Rossi GP., Hypertens Res. August 1, 2018; 41 (8): 578-588.


The age-regulated zinc finger factor ZNF367 is a new modulator of neuroblast proliferation during embryonic neurogenesis., Naef V, Monticelli S, Corsinovi D, Mazzetto MT, Cellerino A, Ori M., Sci Rep. August 7, 2018; 8 (1): 11836.                      


Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC., Argaiz ER, Chavez-Canales M, Ostrosky-Frid M, Rodríguez-Gama A, Vázquez N, Gonzalez-Rodriguez X, Garcia-Valdes J, Hadchouel J, Ellison D, Gamba G., Am J Physiol Renal Physiol. September 1, 2018; 315 (3): F734-F745.


Gli2 is required for the induction and migration of Xenopus laevis neural crest., Cerrizuela S, Vega-López GA, Palacio MB, Tríbulo C, Aybar MJ, Aybar MJ., Mech Dev. December 1, 2018; 154 219-239.                      


Structure-function relationships in the renal NaCl cotransporter (NCC)., Moreno E, de Los Heros P, Plata C, Cutler C, Vega-Mateos A, Vázquez N, Gamba G., Curr Top Membr. January 1, 2019; 83 177-204.


The Many Faces of Xenopus: Xenopus laevis as a Model System to Study Wolf-Hirschhorn Syndrome., Lasser M, Pratt B, Monahan C, Kim SW, Lowery LA., Front Physiol. January 1, 2019; 10 817.                    


Human Pluripotent Stem Cell-Derived Neural Crest Cells for Tissue Regeneration and Disease Modeling., Srinivasan A, Toh YC., Front Mol Neurosci. February 22, 2019; 12 39.  


FoxN3 is necessary for the development of the interatrial septum, the ventricular trabeculae and the muscles at the head/trunk interface in the African clawed frog, Xenopus laevis (Lissamphibia: Anura: Pipidae)., Naumann B, Schmidt J, Olsson L., Dev Dyn. May 1, 2019; 248 (5): 323-336.          


PDGF-B: The missing piece in the mosaic of PDGF family role in craniofacial development., Corsinovi D, Giannetti K, Cericola A, Naef V, Ori M., Dev Dyn. July 1, 2019; 248 (7): 603-612.            


Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome., Greenberg RS, Long HK, Swigut T, Wysocka J., Cell. September 5, 2019; 178 (6): 1421-1436.e24.                                

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