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Summary Expression Phenotypes Gene Literature (500) GO Terms (3) Nucleotides (62) Proteins (38) Interactants (1603) Wiki
XB-GENEPAGE-483208

Papers associated with nodal



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referenced by:

LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter., McKendry R, Hsu SC, Harland RM, Grosschedl R., Dev Biol. December 15, 1997; 192 (2): 420-31.            

Maintenance of asymmetric nodal expression in Xenopus laevis., Lohr JL, Danos MC, Groth TW, Yost HJ., Dev Genet. January 1, 1998; 23 (3): 194-202.      

Evolutionary conservation of mechanisms upstream of asymmetric Nodal expression: reconciling chick and Xenopus., Levin M, Mercola M., Dev Genet. January 1, 1998; 23 (3): 185-93.            

Pre-MBT patterning of early gene regulation in Xenopus: the role of the cortical rotation and mesoderm induction., Ding X, Hausen P, Steinbeisser H., Mech Dev. January 1, 1998; 70 (1-2): 15-24.            

The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities., Hsu DR, Economides AN, Wang X, Eimon PM, Harland RM., Mol Cell. April 1, 1998; 1 (5): 673-83.                  

Smad2 role in mesoderm formation, left-right patterning and craniofacial development., Nomura M, Li E., Nature. June 25, 1998; 393 (6687): 786-90.

Mutant Vg1 ligands disrupt endoderm and mesoderm formation in Xenopus embryos., Joseph EM, Melton DA., Development. July 1, 1998; 125 (14): 2677-85.            

Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry., Rebagliati MR, Toyama R, Fricke C, Haffter P, Dawid IB., Dev Biol. July 15, 1998; 199 (2): 261-72.

Pitx2 determines left-right asymmetry of internal organs in vertebrates., Ryan AK, Blumberg B, Rodriguez-Esteban C, Yonei-Tamura S, Tamura K, Tamura K, Tsukui T, de la Peña J, Sabbagh W, Greenwald J, Choe S, Norris DP, Robertson EJ, Evans RM, Rosenfeld MG, Izpisúa Belmonte JC., Nature. August 6, 1998; 394 (6693): 545-51.

Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling., Sampath K, Rubinstein AL, Cheng AM, Liang JO, Fekany K, Solnica-Krezel L, Korzh V, Halpern ME, Wright CV., Nature. September 10, 1998; 395 (6698): 185-9.

The functional surface charge density of a fast K channel in the myelinated axon of Xenopus laevis., Elinder F, Arhem P., J Membr Biol. September 15, 1998; 165 (2): 175-81.

Molecular mechanisms of vertebrate left-right development., Ramsdell AF, Yost HJ., Trends Genet. November 1, 1998; 14 (11): 459-65.

Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin., Roebroek AJ, Umans L, Pauli IG, Robertson EJ, van Leuven F, Van de Ven WJ, Constam DB., Development. December 1, 1998; 125 (24): 4863-76.

[The head inducer Cerberus in a multivalent extracellular inhibitor]., Agius PE, Piccolo S, De Robertis EM., J Soc Biol. January 1, 1999; 193 (4-5): 347-54.

The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals., Piccolo S, Agius E, Leyns L, Bhattacharyya S, Grunz H, Bouwmeester T, De Robertis EM., Nature. February 25, 1999; 397 (6721): 707-10.

A molecular basis for Smad specificity., Lagna G, Hemmati-Brivanlou A., Dev Dyn. March 1, 1999; 214 (3): 269-77.

derrière: a TGF-beta family member required for posterior development in Xenopus., Sun BI, Bush SM, Collins-Racie LA, LaVallie ER, DiBlasio-Smith EA, Wolfman NM, McCoy JM, Sive HL., Development. April 1, 1999; 126 (7): 1467-82.                    

The EGF-CFC protein one-eyed pinhead is essential for nodal signaling., Gritsman K, Zhang J, Cheng S, Heckscher E, Talbot WS, Schier AF., Cell. April 2, 1999; 97 (1): 121-32.

Xenopus nodal-related signaling is essential for mesendodermal patterning during early embryogenesis., Osada SI, Wright CV., Development. June 1, 1999; 126 (14): 3229-40.                

Retinoic acid is required in the mouse embryo for left-right asymmetry determination and heart morphogenesis., Chazaud C, Chambon P, Dollé P., Development. June 1, 1999; 126 (12): 2589-96.

The SIL gene is required for mouse embryonic axial development and left-right specification., Izraeli S, Lowe LA, Bertness VL, Good DJ, Dorward DW, Kirsch IR, Kuehn MR., Nature. June 17, 1999; 399 (6737): 691-4.

Keeping a close eye on Wnt-1/wg signaling in Xenopus., Gradl D, Kühl M, Wedlich D., Mech Dev. August 1, 1999; 86 (1-2): 3-15.    

Cerberus regulates left-right asymmetry of the embryonic head and heart., Zhu L, Marvin MJ, Gardiner A, Lassar AB, Mercola M, Stern CD, Levin M., Curr Biol. September 9, 1999; 9 (17): 931-8.

The novel Cer-like protein Caronte mediates the establishment of embryonic left-right asymmetry., Rodríguez Esteban C, Capdevila J, Economides AN, Pascual J, Ortiz A, Izpisúa Belmonte JC., Nature. September 16, 1999; 401 (6750): 243-51.

Mode of action of VegT in mesoderm and endoderm formation., Clements D, Friday RV, Woodland HR., Development. November 1, 1999; 126 (21): 4903-11.

Gap junction-mediated transfer of left-right patterning signals in the early chick blastoderm is upstream of Shh asymmetry in the node., Levin M, Mercola M., Development. November 1, 1999; 126 (21): 4703-14.  

In Xenopus embryos, BMP heterodimers are not required for mesoderm induction, but BMP activity is necessary for dorsal/ventral patterning., Eimon PM, Harland RM., Dev Biol. December 1, 1999; 216 (1): 29-40.          

Mesoderm induction in Xenopus is a zygotic event regulated by maternal VegT via TGFbeta growth factors., Kofron M, Demel T, Xanthos J, Lohr J, Sun B, Sive H, Osada S, Wright C, Wylie C, Heasman J., Development. December 1, 1999; 126 (24): 5759-70.

Cardiac looping and the vertebrate left-right axis: antagonism of left-sided Vg1 activity by a right-sided ALK2-dependent BMP pathway., Ramsdell AF, Yost HJ., Development. December 1, 1999; 126 (23): 5195-205.        

Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2., Saijoh Y, Adachi H, Sakuma R, Yeo CY, Yashiro K, Watanabe M, Hashiguchi H, Mochida K, Ohishi S, Kawabata M, Miyazono K, Whitman M, Hamada H., Mol Cell. January 1, 2000; 5 (1): 35-47.    

Embryonic origins of spleen asymmetry., Patterson KD, Drysdale TA, Krieg PA., Development. January 1, 2000; 127 (1): 167-75.            

Pitx2 isoforms: involvement of Pitx2c but not Pitx2a or Pitx2b in vertebrate left-right asymmetry., Schweickert A, Campione1 M, Steinbeisser H, Blum M., Mech Dev. January 1, 2000; 90 (1): 41-51.  

The Yin-Yang of TCF/beta-catenin signaling., Barker N, Morin PJ, Clevers H., Adv Cancer Res. January 1, 2000; 77 1-24.

Regulation of the early expression of the Xenopus nodal-related 1 gene, Xnr1., Hyde CE, Old RW., Development. March 1, 2000; 127 (6): 1221-9.            

Endodermal Nodal-related signals and mesoderm induction in Xenopus., Agius E, Oelgeschläger M, Wessely O, Kemp C, De Robertis EM., Development. March 1, 2000; 127 (6): 1173-83.          

Mesendoderm and left-right brain, heart and gut development are differentially regulated by pitx2 isoforms., Essner JJ, Branford WW, Zhang J, Yost HJ., Development. March 1, 2000; 127 (5): 1081-93.      

The lefty-related factor Xatv acts as a feedback inhibitor of nodal signaling in mesoderm induction and L-R axis development in xenopus., Cheng AM, Thisse B, Thisse C, Wright CV., Development. March 1, 2000; 127 (5): 1049-61.                

Nodal signaling patterns the organizer., Gritsman K, Talbot WS, Schier AF., Development. March 1, 2000; 127 (5): 921-32.

Mechanisms of left-right determination in vertebrates., Capdevila J, Vogan KJ, Tabin CJ, Izpisúa Belmonte JC., Cell. March 31, 2000; 101 (1): 9-21.          

Initiation of eukaryotic DNA replication: origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase alpha., Walter J, Newport J., Mol Cell. April 1, 2000; 5 (4): 617-27.

Cerberus-like is a secreted BMP and nodal antagonist not essential for mouse development., Belo JA, Bachiller D, Agius E, Kemp C, Borges AC, Marques S, Piccolo S, De Robertis EM., Genesis. April 1, 2000; 26 (4): 265-70.

Cloning and characterization of zebrafish smad2, smad3 and smad4., Dick A, Mayr T, Bauer H, Meier A, Hammerschmidt M., Gene. April 4, 2000; 246 (1-2): 69-80.

The HMG-box transcription factor XTcf-4 demarcates the forebrain-midbrain boundary., König A, Gradl D, Kühl M, Wedlich D., Mech Dev. May 1, 2000; 93 (1-2): 211-4.    

Neuroectodermal specification and regionalization of the Spemann organizer in Xenopus., Fetka I, Doederlein G, Bouwmeester T., Mech Dev. May 1, 2000; 93 (1-2): 49-58.          

Nodal-related signals establish mesendodermal fate and trunk neural identity in zebrafish., Feldman B, Dougan ST, Schier AF, Talbot WS., Curr Biol. May 4, 2000; 10 (9): 531-4.

Xenopus kielin: A dorsalizing factor containing multiple chordin-type repeats secreted from the embryonic midline., Matsui M, Mizuseki K, Nakatani J, Nakanishi S, Sasai Y., Proc Natl Acad Sci U S A. May 9, 2000; 97 (10): 5291-6.            

Primary structure requirements for Xenopus nodal-related 3 and a comparison with regions required by Xenopus nodal-related 2., Ezal CH, Marion CD, Smith WC., J Biol Chem. May 12, 2000; 275 (19): 14124-31.

Phenotypic effects in Xenopus and zebrafish suggest that one-eyed pinhead functions as antagonist of BMP signalling., Kiecker C, Müller F, Wu W, Glinka A, Strähle U, Niehrs C., Mech Dev. June 1, 2000; 94 (1-2): 37-46.          

Activin/nodal responsiveness and asymmetric expression of a Xenopus nodal-related gene converge on a FAST-regulated module in intron 1., Osada SI, Saijoh Y, Frisch A, Yeo CY, Adachi H, Watanabe M, Whitman M, Hamada H, Wright CV., Development. June 1, 2000; 127 (11): 2503-14.

The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination., Murcia NS, Richards WG, Yoder BK, Mucenski ML, Dunlap JR, Woychik RP., Development. June 1, 2000; 127 (11): 2347-55.

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