Papers associated with slc12a3

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	The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex., Yang CL, Zhu X, Ellison DH., J Clin Invest. November 1, 2007; 117 (11): 3403-11.
	Phorbol ester stimulation of RasGRP1 regulates the sodium-chloride cotransporter by a PKC-independent pathway., Ko B, Joshi LM, Cooke LL, Vazquez N, Musch MW, Hebert SC, Gamba G, Hoover RS., Proc Natl Acad Sci U S A. December 11, 2007; 104 (50): 20120-5.
	Organization of the pronephric kidney revealed by large-scale gene expression mapping., Raciti D, Reggiani L, Geffers L, Jiang Q, Bacchion F, Subrizi AE, Clements D, Tindal C, Davidson DR, Kaissling B, Brändli AW., Genome Biol. January 1, 2008; 9 (5): R84.
	Identification and gene expression of versican during early development of Xenopus., Casini P, Ori M, Avenoso A, D'Ascola A, Traina P, Mattina W, Perris R, Campo GM, Calatroni A, Nardi I, Campo S., Int J Dev Biol. January 1, 2008; 52 (7): 993-8.
	Cotransporters, WNKs and hypertension: an update., Flatman PW., Curr Opin Nephrol Hypertens. March 1, 2008; 17 (2): 186-92.
	Surface expression of epithelial Na channel protein in rat kidney., Frindt G, Ergonul Z, Palmer LG., J Gen Physiol. June 1, 2008; 131 (6): 617-27.
	Renal Na+-K+-Cl- cotransporter activity and vasopressin-induced trafficking are lipid raft-dependent., Welker P, Böhlick A, Mutig K, Salanova M, Kahl T, Schlüter H, Blottner D, Ponce-Coria J, Gamba G, Bachmann S., Am J Physiol Renal Physiol. September 1, 2008; 295 (3): F789-802.
	WNK3 and WNK4 amino-terminal domain defines their effect on the renal Na+-Cl- cotransporter., San-Cristobal P, Ponce-Coria J, Vázquez N, Bobadilla NA, Gamba G., Am J Physiol Renal Physiol. October 1, 2008; 295 (4): F1199-206.
	Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway., San-Cristobal P, Pacheco-Alvarez D, Richardson C, Ring AM, Vazquez N, Rafiqi FH, Chari D, Kahle KT, Leng Q, Bobadilla NA, Hebert SC, Alessi DR, Lifton RP, Gamba G., Proc Natl Acad Sci U S A. March 17, 2009; 106 (11): 4384-9.
	Renal and brain isoforms of WNK3 have opposite effects on NCCT expression., Glover M, Zuber AM, O'Shaughnessy KM., J Am Soc Nephrol. June 1, 2009; 20 (6): 1314-22.
	WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction., Subramanya AR, Liu J, Ellison DH, Wade JB, Welling PA., J Biol Chem. July 3, 2009; 284 (27): 18471-80.
	Coexistence of normotensive primary aldosteronism in two patients with Gitelman's syndrome and novel thiazide-sensitive Na-Cl cotransporter mutations., Miao Z, Gao Y, Bindels RJ, Yu W, Lang Y, Chen N, Ren H, Sun F, Li Y, Wang X, Shao L., Eur J Endocrinol. August 1, 2009; 161 (2): 275-83.
	Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway., Rozansky DJ, Cornwall T, Subramanya AR, Rogers S, Yang YF, David LL, Zhu X, Yang CL, Ellison DH., J Clin Invest. September 1, 2009; 119 (9): 2601-12.
	The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1., Agrawal R, Tran U, Wessely O., Development. December 1, 2009; 136 (23): 3927-36.
	Xenopus development from late gastrulation to feeding tadpole in simulated microgravity., Olson WM, Wiens DJ, Gaul TL, Rodriguez M, Hauptmeier CL., Int J Dev Biol. January 1, 2010; 54 (1): 167-74.
	RHAMM mRNA expression in proliferating and migrating cells of the developing central nervous system., Casini P, Nardi I, Ori M., Gene Expr Patterns. January 1, 2010; 10 (2-3): 93-7.
	The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity., Tran U, Zakin L, Schweickert A, Agrawal R, Döger R, Blum M, De Robertis EM, Wessely O., Development. April 1, 2010; 137 (7): 1107-16.
	The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice., Leviel F, Hübner CA, Houillier P, Morla L, El Moghrabi S, Brideau G, Hassan H, Hatim H, Parker MD, Kurth I, Kougioumtzes A, Sinning A, Pech V, Riemondy KA, Miller RL, Hummler E, Shull GE, Aronson PS, Doucet A, Wall SM, Chambrey R, Eladari D., J Clin Invest. May 1, 2010; 120 (5): 1627-35.
	On the substrate recognition and negative regulation of SPAK, a kinase modulating Na+-K+-2Cl- cotransport activity., Gagnon KB, Delpire E., Am J Physiol Cell Physiol. September 1, 2010; 299 (3): C614-20.
	Serotonin 2B receptor signaling is required for craniofacial morphogenesis and jaw joint formation in Xenopus., Reisoli E, De Lucchini S, Nardi I, Ori M., Development. September 1, 2010; 137 (17): 2927-37.
	A Single Amino Acid Substitution Makes WNK4 Susceptible to SB 203580 and SB 202190., Glover M, Sweeny C, Davis B, O'Shaughnessy KM., Open Med Chem J. September 3, 2010; 4 57-61.
	The activity of the thiazide-sensitive Na(+)-Cl(-) cotransporter is regulated by protein phosphatase PP4., Glover M, Mercier Zuber A, Figg N, O'Shaughnessy KM., Can J Physiol Pharmacol. October 1, 2010; 88 (10): 986-95.
	Effects of dietary K on cell-surface expression of renal ion channels and transporters., Frindt G, Palmer LG., Am J Physiol Renal Physiol. October 1, 2010; 299 (4): F890-7.
	A single residue in transmembrane domain 11 defines the different affinity for thiazides between the mammalian and flounder NaCl transporters., Castañeda-Bueno M, Vázquez N, Bustos-Jaimes I, Hernández D, Rodríguez-Lobato E, Pacheco-Alvarez D, Cariño-Cortés R, Moreno E, Bobadilla NA, Gamba G., Am J Physiol Renal Physiol. November 1, 2010; 299 (5): F1111-9.
	Inversin relays Frizzled-8 signals to promote proximal pronephros development., Lienkamp S, Ganner A, Boehlke C, Schmidt T, Arnold SJ, Schäfer T, Romaker D, Schuler J, Hoff S, Powelske C, Eifler A, Krönig C, Bullerkotte A, Nitschke R, Kuehn EW, Kim E, Burkhardt H, Brox T, Ronneberger O, Gloy J, Walz G., Proc Natl Acad Sci U S A. November 23, 2010; 107 (47): 20388-93.
	WNK3 is a putative chloride-sensing kinase., Pacheco-Alvarez D, Gamba G., Cell Physiol Biochem. January 1, 2011; 28 (6): 1123-34.
	Cranial neural crest cells on the move: their roles in craniofacial development., Cordero DR, Brugmann S, Chu Y, Bajpai R, Jame M, Helms JA., Am J Med Genet A. February 1, 2011; 155A (2): 270-9.
	Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models., Liu Z, Xie J, Wu T, Truong T, Auchus RJ, Huang CL., Hum Mol Genet. March 1, 2011; 20 (5): 855-66.
	γ-Adducin stimulates the thiazide-sensitive NaCl cotransporter., Dimke H, San-Cristobal P, de Graaf M, Lenders JW, Deinum J, Hoenderop JG, Bindels RJ., J Am Soc Nephrol. March 1, 2011; 22 (3): 508-17.
	Rare mutations in SLC12A1 and SLC12A3 protect against hypertension by reducing the activity of renal salt cotransporters., Acuña R, Martínez-de-la-Maza L, Ponce-Coria J, Vázquez N, Ortal-Vite P, Pacheco-Alvarez D, Bobadilla NA, Gamba G., J Hypertens. March 1, 2011; 29 (3): 475-83.
	WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters., Rinehart J, Vázquez N, Kahle KT, Hodson CA, Ring AM, Gulcicek EE, Louvi A, Bobadilla NA, Gamba G, Lifton RP., J Biol Chem. August 26, 2011; 286 (34): 30171-80.
	Similar effects of all WNK3 variants on SLC12 cotransporters., Cruz-Rangel S, Melo Z, Vázquez N, Meade P, Bobadilla NA, Pasantes-Morales H, Gamba G, Mercado A., Am J Physiol Cell Physiol. September 1, 2011; 301 (3): C601-8.
	Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway., Arroyo JP, Lagnaz D, Ronzaud C, Vázquez N, Ko BS, Moddes L, Ruffieux-Daidié D, Hausel P, Koesters R, Yang B, Stokes JB, Hoover RS, Gamba G, Staub O., J Am Soc Nephrol. September 1, 2011; 22 (9): 1707-19.
	WNK3-SPAK interaction is required for the modulation of NCC and other members of the SLC12 family., Pacheco-Alvarez D, Vázquez N, Castañeda-Bueno M, de-Los-Heros P, Cortes-González C, Moreno E, Meade P, Bobadilla NA, Gamba G., Cell Physiol Biochem. January 1, 2012; 29 (1-2): 291-302.
	Hyaluronan is required for cranial neural crest cells migration and craniofacial development., Casini P, Nardi I, Ori M., Dev Dyn. February 1, 2012; 241 (2): 294-302.
	A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo., Oi K, Sohara E, Rai T, Misawa M, Chiga M, Alessi DR, Sasaki S, Uchida S., Biol Open. February 15, 2012; 1 (2): 120-7.
	Novel NCC mutants and functional analysis in a new cohort of patients with Gitelman syndrome., Glaudemans B, Yntema HG, San-Cristobal P, Schoots J, Pfundt R, Kamsteeg EJ, Bindels RJ, Knoers NV, Hoenderop JG, Hoefsloot LH., Eur J Hum Genet. March 1, 2012; 20 (3): 263-70.
	Mutations in IRX5 impair craniofacial development and germ cell migration via SDF1., Bonnard C, Strobl AC, Shboul M, Lee H, Merriman B, Nelson SF, Ababneh OH, Uz E, Güran T, Kayserili H, Hamamy H, Reversade B., Nat Genet. May 13, 2012; 44 (6): 709-13.
	Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent process., Castañeda-Bueno M, Cervantes-Pérez LG, Vázquez N, Uribe N, Kantesaria S, Morla L, Bobadilla NA, Doucet A, Alessi DR, Gamba G., Proc Natl Acad Sci U S A. May 15, 2012; 109 (20): 7929-34.
	Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest., Rada-Iglesias A, Bajpai R, Prescott S, Brugmann SA, Swigut T, Wysocka J., Cell Stem Cell. November 2, 2012; 11 (5): 633-48.
	Characterization of a novel phosphorylation site in the sodium-chloride cotransporter, NCC., Rosenbaek LL, Assentoft M, Pedersen NB, MacAulay N, Fenton RA., J Physiol. December 1, 2012; 590 (23): 6121-39.
	Cell differentiation of pluripotent tissue sheets immobilized on supported membranes displaying cadherin-11., Körner A, Deichmann C, Rossetti FF, Köhler A, Konovalov OV, Wedlich D, Tanaka M., PLoS One. January 1, 2013; 8 (2): e54749.
	Insulin increases the functional activity of the renal NaCl cotransporter., Chávez-Canales M, Arroyo JP, Ko B, Vázquez N, Bautista R, Castañeda-Bueno M, Bobadilla NA, Hoover RS, Gamba G., J Hypertens. February 1, 2013; 31 (2): 303-11.
	Calponin 2 acts as an effector of noncanonical Wnt-mediated cell polarization during neural crest cell migration., Ulmer B, Hagenlocher C, Schmalholz S, Kurz S, Schweickert A, Kohl A, Roth L, Sela-Donenfeld D, Blum M., Cell Rep. March 28, 2013; 3 (3): 615-21.
	Regulation of G-protein signaling via Gnas is required to regulate proximal tubular growth in the Xenopus pronephros., Zhang B, Romaker D, Ferrell N, Wessely O., Dev Biol. April 1, 2013; 376 (1): 31-42.
	Efficient high-throughput sequencing of a laser microdissected chromosome arm., Seifertova E, Zimmerman LB, Gilchrist MJ, Macha J, Kubickova S, Cernohorska H, Zarsky V, Owens ND, Sesay AK, Tlapakova T, Krylov V., BMC Genomics. May 28, 2013; 14 357.
	Disease-causing mutations in KLHL3 impair its effect on WNK4 degradation., Wu G, Peng JB., FEBS Lett. June 19, 2013; 587 (12): 1717-22.
	The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling., Wang F, Hu W, Xian J, Ohnuma S, Brenton JD., Dev Biol. July 1, 2013; 379 (1): 16-27.
	Expression and functional characterization of Xhmg-at-hook genes in Xenopus laevis., Macrì S, Sgarra R, Ros G, Maurizio E, Zammitti S, Milani O, Onorati M, Vignali R, Manfioletti G., PLoS One. July 1, 2013; 8 (7): e69866.
	Loss of Xenopus cadherin-11 leads to increased Wnt/β-catenin signaling and up-regulation of target genes c-myc and cyclin D1 in neural crest., Koehler A, Schlupf J, Schneider M, Kraft B, Winter C, Kashef J., Dev Biol. November 1, 2013; 383 (1): 132-45.

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