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Summary Expression Phenotypes Gene Literature (111) GO Terms (8) Nucleotides (76) Proteins (47) Interactants (1148) Wiki
XB-GENEPAGE-478760

Papers associated with six3



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Ectopic lens induction in fish in response to the murine homeobox gene Six3., Oliver G, Loosli F, Köster R, Wittbrodt J, Gruss P., Mech Dev. December 1, 1996; 60 (2): 233-9.

Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly., Wallis DE, Roessler E, Hehr U, Nanni L, Wiltshire T, Richieri-Costa A, Gillessen-Kaesbach G, Zackai EH, Rommens J, Muenke M., Nat Genet. June 1, 1999; 22 (2): 196-8.

Role of Xrx1 in Xenopus eye and anterior brain development., Andreazzoli M, Gestri G, Angeloni D, Menna E, Barsacchi G., Development. June 1, 1999; 126 (11): 2451-60.            

Giant eyes in Xenopus laevis by overexpression of XOptx2., Zuber ME, Perron M, Philpott A, Bang A, Harris WA., Cell. August 6, 1999; 98 (3): 341-52.              

Pax6 induces ectopic eyes in a vertebrate., Chow RL, Altmann CR, Lang RA, Hemmati-Brivanlou A., Development. October 1, 1999; 126 (19): 4213-22.              

A novel fork head gene mediates early steps during Xenopus lens formation., Kenyon KL, Moody SA, Jamrich M., Development. November 1, 1999; 126 (22): 5107-16.            

Cloning and expression of xSix3, the Xenopus homologue of murine Six3., Zhou X, Hollemann T, Pieler T, Gruss P., Mech Dev. March 1, 2000; 91 (1-2): 327-30.  

Expanded retina territory by midbrain transformation upon overexpression of Six6 (Optx2) in Xenopus embryos., Bernier G, Panitz F, Zhou X, Zhou X, Hollemann T, Gruss P, Pieler T., Mech Dev. May 1, 2000; 93 (1-2): 59-69.            

Molecular cloning and embryonic expression of Xenopus Six homeobox genes., Ghanbari H, Seo HC, Fjose A, Brändli AW., Mech Dev. March 1, 2001; 101 (1-2): 271-7.                                                                        

Neural and head induction by insulin-like growth factor signals., Pera EM, Wessely O, Li SY, De Robertis EM., Dev Cell. November 1, 2001; 1 (5): 655-65.    

Characterizing gene expression during lens formation in Xenopus laevis: evaluating the model for embryonic lens induction., Henry JJ, Carinato ME, Schaefer JJ, Wolfe AD, Walter BE, Perry KJ, Elbl TN., Dev Dyn. June 1, 2002; 224 (2): 168-85.        

L-Maf, a downstream target of Pax6, is essential for chick lens development., Reza HM, Ogino H, Yasuda K., Mech Dev. August 1, 2002; 116 (1-2): 61-73.

A screen for co-factors of Six3., Tessmar K, Loosli F, Wittbrodt J., Mech Dev. September 1, 2002; 117 (1-2): 103-13.                  

Six3 and Six6 activity is modulated by members of the groucho family., López-Ríos J, Tessmar K, Loosli F, Wittbrodt J, Bovolenta P., Development. January 1, 2003; 130 (1): 185-95.

Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins., Postigo AA, Depp JL, Taylor JJ, Kroll KL., EMBO J. May 15, 2003; 22 (10): 2453-62.

Specification of the vertebrate eye by a network of eye field transcription factors., Zuber ME, Gestri G, Viczian AS, Barsacchi G, Harris WA., Development. November 1, 2003; 130 (21): 5155-67.        

Regulation of vertebrate eye development by Rx genes., Bailey TJ, El-Hodiri H, Zhang L, Shah R, Mathers PH, Jamrich M., Int J Dev Biol. January 1, 2004; 48 (8-9): 761-70.    

Direct interaction of geminin and Six3 in eye development., Del Bene F, Tessmar-Raible K, Wittbrodt J., Nature. February 19, 2004; 427 (6976): 745-9.

Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus., Kuroda H, Wessely O, De Robertis EM., PLoS Biol. May 1, 2004; 2 (5): E92.                

Xenopus XsalF: anterior neuroectodermal specification by attenuating cellular responsiveness to Wnt signaling., Onai T, Sasai N, Matsui M, Sasai Y., Dev Cell. July 1, 2004; 7 (1): 95-106.            

Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm., Kurokawa D, Takasaki N, Kiyonari H, Nakayama R, Kimura-Yoshida C, Matsuo I, Aizawa S., Development. July 1, 2004; 131 (14): 3307-17.      

Systematic screening for genes specifically expressed in the anterior neuroectoderm during early Xenopus development., Takahashi N, Tochimoto N, Ohmori SY, Mamada H, Itoh M, Inamori M, Shinga J, Osada S, Taira M., Int J Dev Biol. January 1, 2005; 49 (8): 939-51.                                    

Olfactory and lens placode formation is controlled by the hedgehog-interacting protein (Xhip) in Xenopus., Cornesse Y, Pieler T, Hollemann T., Dev Biol. January 15, 2005; 277 (2): 296-315.                          

Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF., Yamamoto A, Nagano T, Takehara S, Hibi M, Aizawa S., Cell. January 28, 2005; 120 (2): 223-35.                      

Frizzled 5 signaling governs the neural potential of progenitors in the developing Xenopus retina., Van Raay TJ, Moore KB, Iordanova I, Steele M, Jamrich M, Harris WA, Vetter ML., Neuron. April 7, 2005; 46 (1): 23-36.                        

Six3 functions in anterior neural plate specification by promoting cell proliferation and inhibiting Bmp4 expression., Gestri G, Carl M, Appolloni I, Wilson SW, Barsacchi G, Andreazzoli M., Development. May 1, 2005; 132 (10): 2401-13.              

Genetic analysis of metamorphic and premetamorphic Xenopus ciliary marginal zone., Casarosa S, Leone P, Cannata S, Santini F, Pinchera A, Barsacchi G, Andreazzoli M., Dev Dyn. June 1, 2005; 233 (2): 646-51.    

AP-2alpha selectively regulates fragile X mental retardation-1 gene transcription during embryonic development., Lim JH, Booker AB, Luo T, Williams T, Furuta Y, Lagutin O, Oliver G, Sargent TD, Fallon JR., Hum Mol Genet. July 15, 2005; 14 (14): 2027-34.    

A small gem with great powers: geminin keeps neural progenitors thriving., Aigner S, Gage FH., Dev Cell. August 1, 2005; 9 (2): 171-2.

Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos., Reversade B, Kuroda H, Lee H, Mays A, De Robertis EM., Development. August 1, 2005; 132 (15): 3381-92.            

Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic field., Reversade B, De Robertis EM., Cell. December 16, 2005; 123 (6): 1147-60.                      

Nucleosome regulator Xhmgb3 is required for cell proliferation of the eye and brain as a downstream target of Xenopus rax/Rx1., Terada K, Kitayama A, Kanamoto T, Ueno N, Furukawa T., Dev Biol. March 15, 2006; 291 (2): 398-412.          

Expression of Xenopus laevis Lhx2 during eye development and evidence for divergent expression among vertebrates., Viczian AS, Bang AG, Harris WA, Zuber ME., Dev Dyn. April 1, 2006; 235 (4): 1133-41.                  

Isolation and characterization of a novel gene, xMADML, involved in Xenopus laevis eye development., Elkins MB, Henry JJ., Dev Dyn. July 1, 2006; 235 (7): 1845-57.                  

Cholesterol homeostasis in development: the role of Xenopus 7-dehydrocholesterol reductase (Xdhcr7) in neural development., Tadjuidje E, Hollemann T., Dev Dyn. August 1, 2006; 235 (8): 2095-110.                          

Cloning and developmental expression of the Xenopus homeobox gene Xvsx1., D'Autilia S, Decembrini S, Casarosa S, He RQ, Barsacchi G, Cremisi F, Andreazzoli M., Dev Genes Evol. December 1, 2006; 216 (12): 829-34.

PP2A:B56epsilon is required for eye induction and eye field separation., Rorick AM, Mei W, Liette NL, Phiel C, El-Hodiri HM, Yang J., Dev Biol. February 15, 2007; 302 (2): 477-93.                  

Alterations of rx1 and pax6 expression levels at neural plate stages differentially affect the production of retinal cell types and maintenance of retinal stem cell qualities., Zaghloul NA, Moody SA., Dev Biol. June 1, 2007; 306 (1): 222-40.                      

The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning., Sander V, Reversade B, De Robertis EM., EMBO J. June 20, 2007; 26 (12): 2955-65.              

The homeodomain factor Xanf represses expression of genes in the presumptive rostral forebrain that specify more caudal brain regions., Ermakova GV, Solovieva EA, Martynova NY, Zaraisky AG., Dev Biol. July 15, 2007; 307 (2): 483-97.        

Geminin is cleaved by caspase-3 during apoptosis in Xenopus egg extracts., Auziol C, Méchali M, Maiorano D., Biochem Biophys Res Commun. September 21, 2007; 361 (2): 276-80.

Purine-mediated signalling triggers eye development., Massé K, Bhamra S, Eason R, Dale N, Jones EA., Nature. October 25, 2007; 449 (7165): 1058-62.

Unexpected activities of Smad7 in Xenopus mesodermal and neural induction., de Almeida I, Rolo A, Batut J, Hill C, Stern CD, Linker C., Mech Dev. January 1, 2008; 125 (5-6): 421-31.              

Regulation of TGF-(beta) signalling by N-acetylgalactosaminyltransferase-like 1., Herr P, Korniychuk G, Yamamoto Y, Grubisic K, Oelgeschläger M., Development. May 1, 2008; 135 (10): 1813-22.                    

Investigation of Frizzled-5 during embryonic neural development in mouse., Burns CJ, Zhang J, Brown EC, Van Bibber AM, Van Es J, Clevers H, Ishikawa TO, Taketo MM, Vetter ML, Fuhrmann S., Dev Dyn. June 1, 2008; 237 (6): 1614-26.

Expression study of cadherin7 and cadherin20 in the embryonic and adult rat central nervous system., Takahashi M, Osumi N., BMC Dev Biol. June 23, 2008; 8 87.                

Zebrafish olfactomedin 1 regulates retinal axon elongation in vivo and is a modulator of Wnt signaling pathway., Nakaya N, Lee HS, Takada Y, Tzchori I, Tomarev SI., J Neurosci. July 30, 2008; 28 (31): 7900-10.

Crossveinless-2 Is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning., Ambrosio AL, Taelman VF, Lee HX, Lee HX, Metzinger CA, Coffinier C, De Robertis EM., Dev Cell. August 1, 2008; 15 (2): 248-60.                            

Hairy2-Id3 interactions play an essential role in Xenopus neural crest progenitor specification., Nichane M, de Crozé N, Ren X, Souopgui J, Monsoro-Burq AH, Bellefroid EJ., Dev Biol. October 15, 2008; 322 (2): 355-67.                          

Involvement of an inner nuclear membrane protein, Nemp1, in Xenopus neural development through an interaction with the chromatin protein BAF., Mamada H, Takahashi N, Taira M., Dev Biol. March 15, 2009; 327 (2): 497-507.            

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