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Summary Expression Phenotypes Gene Literature (315) GO Terms (11) Nucleotides (95) Proteins (63) Interactants (873) Wiki

Papers associated with cftr

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A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development., Lee J, Møller AF, Chae S, Bussek A, Park TJ, Kim Y, Lee HS, Pers TH, Kwon T, Sedzinski J, Natarajan KN., Sci Adv. April 7, 2023; 9 (14): eadd5745.                                                          

Oxalate secretion is stimulated by a cAMP-dependent pathway in the mouse cecum., Whittamore JM, Hatch M., Pflugers Arch. February 1, 2023; 475 (2): 249-266.

The Effect of Dynasore Upon the Negative Interaction Between ENaC and CFTR Channels in Xenopus laevis Oocytes., Palma AG, Kotsias BA., J Membr Biol. February 1, 2022; 255 (1): 61-69.

Molecular pathology of the R117H cystic fibrosis mutation is explained by loss of a hydrogen bond., Simon MA, Csanády L., Elife. December 6, 2021; 10                 

A nonolfactory shark adenosine receptor activates CFTR with unique pharmacology and structural features., Bhanot S, Hemminger G, Martin CL, Aller SG, Forrest JN., Am J Physiol Cell Physiol. May 1, 2021; 320 (5): C892-C901.

UXT chaperone prevents proteotoxicity by acting as an autophagy adaptor for p62-dependent aggrephagy., Yoon MJ, Choi B, Kim EJ, Ohk J, Yang C, Choi YG, Lee J, Kang C, Song HK, Kim YK, Woo JS, Cho Y, Choi EJ, Jung H, Kim C., Nat Commun. March 29, 2021; 12 (1): 1955.                

Clinical and molecular characterization of the R751L-CFTR mutation., Haq IJ, Althaus M, Gardner AI, Yeoh HY, Joshi U, Saint-Criq V, Verdon B, Townshend J, O'Brien C, Ben-Hamida M, Thomas M, Bourke S, van der Sluijs P, Braakman I, Ward C, Gray MA, Brodlie M., Am J Physiol Lung Cell Mol Physiol. February 1, 2021; 320 (2): L288-L300.

Electrophysiological Approaches for the Study of Ion Channel Function., Cui G, Cottrill KA, McCarty NA., Methods Mol Biol. January 1, 2021; 2302 49-67.

FXYD protein isoforms differentially modulate human Na/K pump function., Meyer DJ, Bijlani S, de Sautu M, Spontarelli K, Young VC, Gatto C, Artigas P., J Gen Physiol. December 7, 2020; 152 (12):                         

Simple binding of protein kinase A prior to phosphorylation allows CFTR anion channels to be opened by nucleotides., Mihályi C, Iordanov I, Töröcsik B, Csanády L., Proc Natl Acad Sci U S A. September 1, 2020; 117 (35): 21740-21746.

VX-770-mediated potentiation of numerous human CFTR disease mutants is influenced by phosphorylation level., Cui G, Stauffer BB, Imhoff BR, Rab A, Hong JS, Sorscher EJ, McCarty NA., Sci Rep. September 17, 2019; 9 (1): 13460.              

Cystic fibrosis drug ivacaftor stimulates CFTR channels at picomolar concentrations., Csanády L, Töröcsik B., Elife. June 17, 2019; 8           

Engineered transfer RNAs for suppression of premature termination codons., Lueck JD, Yoon JS, Perales-Puchalt A, Mackey AL, Infield DT, Behlke MA, Pope MR, Weiner DB, Skach WR, McCray PB, Ahern CA., Nat Commun. February 18, 2019; 10 (1): 822.          

Retinoic acid promotes stem cell differentiation and embryonic development by transcriptionally activating CFTR., Li X, Fok KL, Guo J, Wang Y, Liu Z, Chen Z, Wang C, Ruan YC, Yu SS, Zhao H, Wu J, Jiang X, Chan HC., Biochim Biophys Acta Mol Cell Res. April 1, 2018; 1865 (4): 605-615.

CFTR supports cell death through ROS-dependent activation of TMEM16F (anoctamin 6)., Simões F, Ousingsawat J, Wanitchakool P, Fonseca A, Cabrita I, Benedetto R, Schreiber R, Kunzelmann K., Pflugers Arch. February 1, 2018; 470 (2): 305-314.

The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations., Agrawal PB, Wang R, Li HL, Schmitz-Abe K, Simone-Roach C, Chen J, Shi J, Louie T, Sheng S, Towne MC, Brainson CF, Matthay MA, Kim CF, Bamshad M, Emond MJ, Gerard NP, Kleyman TR, Gerard C., Am J Respir Cell Mol Biol. December 1, 2017; 57 (6): 711-720.

Asymmetry of movements in CFTR's two ATP sites during pore opening serves their distinct functions., Sorum B, Töröcsik B, Csanády L., Elife. September 25, 2017; 6                         

Mammalian odorant receptor tuning breadth persists across distinct odorant panels., Kepchia D, Sherman B, Haddad R, Luetje CW., PLoS One. September 8, 2017; 12 (9): e0185329.          

Hydrogen sulfide stimulates CFTR in Xenopus oocytes by activation of the cAMP/PKA signalling axis., Perniss A, Preiss K, Nier M, Althaus M., Sci Rep. June 14, 2017; 7 (1): 3517.        

Bacterial Sphingomyelinase is a State-Dependent Inhibitor of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR)., Stauffer BB, Cui G, Cottrill KA, Infield DT, McCarty NA., Sci Rep. June 7, 2017; 7 (1): 2931.                

Protein kinase A regulates C-terminally truncated CaV 1.2 in Xenopus oocytes: roles of N- and C-termini of the α1C subunit., Oz S, Pankonien I, Belkacemi A, Flockerzi V, Klussmann E, Haase H, Dascal N., J Physiol. May 15, 2017; 595 (10): 3181-3202.

Molecular Structure of the Human CFTR Ion Channel., Liu F, Zhang Z, Csanády L, Gadsby DC, Chen J., Cell. March 23, 2017; 169 (1): 85-95.e8.

δβγ-ENaC is inhibited by CFTR but stimulated by cAMP in Xenopus laevis oocytes., Rauh R, Hoerner C, Korbmacher C., Am J Physiol Lung Cell Mol Physiol. February 1, 2017; 312 (2): L277-L287.

Loss of Cystic Fibrosis Transmembrane Regulator Impairs Intestinal Oxalate Secretion., Knauf F, Thomson RB, Heneghan JF, Jiang Z, Adebamiro A, Thomson CL, Barone C, Asplin JR, Egan ME, Alper SL, Aronson PS., J Am Soc Nephrol. January 1, 2017; 28 (1): 242-249.

CFTR-β-catenin interaction regulates mouse embryonic stem cell differentiation and embryonic development., Liu Z, Guo J, Wang Y, Weng Z, Huang B, Yu MK, Zhang X, Yuan P, Zhao H, Chan WY, Jiang X, Chan HC., Cell Death Differ. January 1, 2017; 24 (1): 98-110.

Functional and molecular identification of a TASK-1 potassium channel regulating chloride secretion through CFTR channels in the shark rectal gland: implications for cystic fibrosis., Telles CJ, Decker SE, Motley WW, Peters AW, Mehr AP, Frizzell RA, Forrest JN., Am J Physiol Cell Physiol. December 1, 2016; 311 (6): C884-C894.

Potentiators exert distinct effects on human, murine, and Xenopus CFTR., Cui G, Khazanov N, Stauffer BB, Infield DT, Imhoff BR, Senderowitz H, McCarty NA., Am J Physiol Lung Cell Mol Physiol. August 1, 2016; 311 (2): L192-207.

Rattlesnake Phospholipase A2 Increases CFTR-Chloride Channel Current and Corrects ∆F508CFTR Dysfunction: Impact in Cystic Fibrosis., Faure G, Bakouh N, Lourdel S, Odolczyk N, Premchandar A, Servel N, Hatton A, Ostrowski MK, Xu H, Saul FA, Moquereau C, Bitam S, Pranke I, Planelles G, Teulon J, Herrmann H, Roldan A, Zielenkiewicz P, Dadlez M, Lukacs GL, Sermet-Gaudelus I, Ollero M, Corringer PJ, Edelman A., J Mol Biol. July 17, 2016; 428 (14): 2898-915.

Obligate coupling of CFTR pore opening to tight nucleotide-binding domain dimerization., Mihályi C, Töröcsik B, Csanády L., Elife. June 21, 2016; 5         

CFTR channel in oocytes from Xenopus laevis and its regulation by xShroom1 protein., Palma AG, Galizia L, Kotsias BA, Marino GI., Pflugers Arch. May 1, 2016; 468 (5): 871-80.

Mechanosensitive activation of CFTR by increased cell volume and hydrostatic pressure but not shear stress., Vitzthum C, Clauss WG, Fronius M., Biochim Biophys Acta. November 1, 2015; 1848 (11 Pt A): 2942-51.

Murine and human CFTR exhibit different sensitivities to CFTR potentiators., Cui G, McCarty NA., Am J Physiol Lung Cell Mol Physiol. October 1, 2015; 309 (7): L687-99.

Functional characteristics of L1156F-CFTR associated with alcoholic chronic pancreatitis in Japanese., Kondo S, Fujiki K, Ko SB, Yamamoto A, Nakakuki M, Ito Y, Shcheynikov N, Kitagawa M, Naruse S, Ishiguro H., Am J Physiol Gastrointest Liver Physiol. August 15, 2015; 309 (4): G260-9.

Cysteine accessibility probes timing and extent of NBD separation along the dimer interface in gating CFTR channels., Chaves LA, Gadsby DC., J Gen Physiol. April 1, 2015; 145 (4): 261-83.                      

ANP and CNP activate CFTR expressed in Xenopus laevis oocytes by direct activation of PKA., Stahl K, Stahl M, de Jonge HR, Forrest JN., J Recept Signal Transduct Res. January 1, 2015; 35 (5): 493-504.

Insulin is involved in transcriptional regulation of NKCC and the CFTR Cl(-) channel through PI3K activation and ERK inactivation in renal epithelial cells., Sun H, Niisato N, Inui T, Marunaka Y., J Physiol Sci. November 1, 2014; 64 (6): 433-43.

ERp29 regulates epithelial sodium channel functional expression by promoting channel cleavage., Grumbach Y, Bikard Y, Suaud L, Chanoux RA, Rubenstein RC., Am J Physiol Cell Physiol. October 15, 2014; 307 (8): C701-9.

Counteracting suppression of CFTR and voltage-gated K+ channels by a bacterial pathogenic factor with the natural product tannic acid., Ramu Y, Xu Y, Xu Y, Shin HG, Lu Z., Elife. October 14, 2014; 3 e03683.        

Structure-activity analysis of a CFTR channel potentiator: Distinct molecular parts underlie dual gating effects., Csanády L, Töröcsik B., J Gen Physiol. October 1, 2014; 144 (4): 321-36.                    

Cystic fibrosis transmembrane conductance regulator (CFTR) potentiators protect G551D but not ΔF508 CFTR from thermal instability., Liu X, Dawson DC., Biochemistry. September 9, 2014; 53 (35): 5613-8.        

Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR., Cui G, Rahman KS, Infield DT, Kuang C, Prince CZ, McCarty NA., J Gen Physiol. August 1, 2014; 144 (2): 159-79.                          

Discovery of novel ligands for mouse olfactory receptor MOR42-3 using an in silico screening approach and in vitro validation., Bavan S, Sherman B, Luetje CW, Abaffy T., PLoS One. March 17, 2014; 9 (3): e92064.            

Serum and glucocorticoid-inducible kinase1 increases plasma membrane wt-CFTR in human airway epithelial cells by inhibiting its endocytic retrieval., Bomberger JM, Coutermarsh BA, Barnaby RL, Sato JD, Chapline MC, Stanton BA., PLoS One. February 19, 2014; 9 (2): e89599.                  

Aqueous cigarette smoke extract induces a voltage-dependent inhibition of CFTR expressed in Xenopus oocytes., Moran AR, Norimatsu Y, Dawson DC, MacDonald KD., Am J Physiol Lung Cell Mol Physiol. February 1, 2014; 306 (3): L284-91.

Catalyst-like modulation of transition states for CFTR channel opening and closing: new stimulation strategy exploits nonequilibrium gating., Csanády L, Töröcsik B., J Gen Physiol. February 1, 2014; 143 (2): 269-87.                        

Comparative expression analysis of cysteine-rich intestinal protein family members crip1, 2 and 3 during Xenopus laevis embryogenesis., Hempel A, Kühl SJ., Int J Dev Biol. January 1, 2014; 58 (10-12): 841-9.                                              

Characterization of SLC26A9 in patients with CF-like lung disease., Bakouh N, Bienvenu T, Thomas A, Ehrenfeld J, Liote H, Roussel D, Duquesnoy P, Farman N, Viel M, Cherif-Zahar B, Amselem S, Taam RA, Edelman A, Planelles G, Sermet-Gaudelus I., Hum Mutat. October 1, 2013; 34 (10): 1404-14.

A characterization of the Manduca sexta serotonin receptors in the context of olfactory neuromodulation., Dacks AM, Reale V, Pi Y, Zhang W, Dacks JB, Nighorn AJ, Evans PD., PLoS One. July 18, 2013; 8 (7): e69422.          

Two salt bridges differentially contribute to the maintenance of cystic fibrosis transmembrane conductance regulator (CFTR) channel function., Cui G, Freeman CS, Knotts T, Prince CZ, Kuang C, McCarty NA., J Biol Chem. July 12, 2013; 288 (28): 20758-67.

Conformational changes in the catalytically inactive nucleotide-binding site of CFTR., Csanády L, Mihályi C, Szollosi A, Töröcsik B, Vergani P., J Gen Physiol. July 1, 2013; 142 (1): 61-73.                  

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