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TPX2 level correlates with cholangiocarcinoma cell proliferation, apoptosis, and EMT. , Zou Z, Zheng B, Li J, Lv X, Zhang H , Yu F, Kong L, Li Y, Yu M, Fang L, Liang B., Biomed Pharmacother. November 1, 2018; 107 1286-1293.
AKT signaling displays multifaceted functions in neural crest development. , Sittewelle M, Monsoro-Burq AH ., Dev Biol. December 1, 2018; 444 Suppl 1 S144-S155.
Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer. , Chen M, Zhang H , Zhang G, Zhong A, Ma Q, Kai J, Tong Y, Xie S, Wang Y, Zheng H, Guo L, Lu R., Biochem Biophys Res Commun. December 9, 2018; 507 (1-4): 74-82.
DNp73-induced degradation of tyrosinase links depigmentation with EMT-driven melanoma progression. , Fürst K, Steder M, Logotheti S, Angerilli A, Spitschak A, Marquardt S, Schumacher T, Engelmann D, Herchenröder O, Rupp RAW , Pützer BM., Cancer Lett. February 1, 2019; 442 299-309.
Dissociation Process of a MDM2/p53 Complex Investigated by Parallel Cascade Selection Molecular Dynamics and the Markov State Model. , Tran DP, Kitao A., J Phys Chem B. March 21, 2019; 123 (11): 2469-2478.
X-linked α-thalassemia with mental retardation is downstream of protein kinase A in the meiotic cell cycle signaling cascade in Xenopus oocytes and is dynamically regulated in response to DNA damage†. , O'Shea LC, Fair T, Hensey C., Biol Reprod. May 1, 2019; 100 (5): 1238-1249.
Morpholinos Do Not Elicit an Innate Immune Response during Early Xenopus Embryogenesis. , Paraiso KD , Blitz IL , Zhou JJ , Cho KWY ., Dev Cell. May 20, 2019; 49 (4): 643-650.e3.
Characteristics of in Vivo Model Systems for Ovarian Cancer Studies. , Tudrej P, Kujawa KA, Cortez AJ, Lisowska KM., Diagnostics (Basel). September 14, 2019; 9 (3):
NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress. , Han D, Schomacher L, Schüle KM, Mallick M, Musheev MU, Karaulanov E, Krebs L, von Seggern A, Niehrs C ., Elife. September 30, 2019; 8
Repression of Inappropriate Gene Expression in the Vertebrate Embryonic Ectoderm. , Reich S, Weinstein DC ., Genes (Basel). November 6, 2019; 10 (11):
Dehydration stress alters the mitogen-activated-protein kinase signaling and chaperone stress response in Xenopus laevis. , Wu CW , Tessier SN, Storey KB ., Comp Biochem Physiol B Biochem Mol Biol. January 1, 2020; 246-247 110461.
RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis. , Naert T, Dimitrakopoulou D, Tulkens D, Demuynck S, Carron M, Noelanders R, Eeckhout L, Van Isterdael G, Deforce D, Vanhove C, Van Dorpe J, Creytens D, Vleminckx K , Vleminckx K ., Oncogene. March 1, 2020; 39 (13): 2692-2706.
Understanding MAPK Signaling Pathways in Apoptosis. , Yue J, López JM., Int J Mol Sci. March 28, 2020; 21 (7):
PACT/PRKRA and p53 regulate transcriptional activity of DMRT1. , Fujitani K, Otomo A, Nagayama Y, Tachibana T, Kato R, Kawashima Y, Kodera Y, Kato T , Takada S, Tamura K , Takamatsu N , Ito M., Genet Mol Biol. March 30, 2020; 43 (2): e20190017.
Sub-lethal effects of calcium dinonylnaphthalenesulfonate on Western clawed frog embryos. , Wallace SJ, Leclerc AJA, Prosser R, de Solla SR, Balakrishnan V, Langlois VS ., Comp Biochem Physiol Part D Genomics Proteomics. June 1, 2020; 34 100658.
Tumor-Suppressive MicroRNA-216b Binds to TPX2, Activating the p53 Signaling in Human Cutaneous Squamous Cell Carcinoma. , Feng C, Zhang HL , Zeng A, Bai M, Wang XJ ., Mol Ther Nucleic Acids. June 5, 2020; 20 186-195.
Function and molecular mechanisms of APE2 in genome and epigenome integrity. , Lin Y, McMahon A, Driscoll G, Bullock S, Zhao J, Yan S ., Mutat Res Rev Mutat Res. January 1, 2021; 787 108347.
Rab11fip5 regulates telencephalon development via ephrinB1 recycling. , Yoon J, Garo J, Lee M, Sun J, Hwang YS, Daar IO ., Development. February 2, 2021; 148 (3):
High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability. , Matson DR, Denu RA, Zasadil LM, Burkard ME, Weaver BA, Flynn C, Stukenberg PT ., BMC Cancer. February 23, 2021; 21 (1): 186.
Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant. , Magnussen HM, Huang DT., J Mol Biol. March 5, 2021; 433 (5): 166807.
Identification of a unique endoplasmic retention motif in the Xenopus GIRK5 channel and its contribution to oocyte maturation. , Rangel-Garcia CI, Salvador C, Chavez-Garcia K, Diaz-Bello B, Lopez-Gonzalez Z, Vazquez-Cruz L, Angel Vazquez-Martinez J, Ortiz-Navarrete V, Riveros-Rosas H, Escobar LI., FEBS Open Bio. April 1, 2021; 11 (4): 1093-1108.
The Multifaceted Roles of USP15 in Signal Transduction. , Das T, Song EJ, Kim EE ., Int J Mol Sci. April 29, 2021; 22 (9):
Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness. , Cheng J, Tsuda M, Okolotowicz K, Dwyer M, Bushway PJ, Colas AR, Lancman JJ, Schade D, Perea-Gil I, Bruyneel AAN, Lee J , Vadgama N, Quach J, McKeithan WL, Biechele TL, Wu JC , Moon RT , Si Dong PD, Karakikes I, Cashman JR, Mercola M ., Cell Chem Biol. May 20, 2021; 28 (5): 625-635.e5.
Temporal transcriptomic profiling reveals dynamic changes in gene expression of Xenopus animal cap upon activin treatment. , Satou-Kobayashi Y, Kim JD , Fukamizu A, Asashima M ., Sci Rep. July 15, 2021; 11 (1): 14537.
The Ribosomal Protein L5 Functions During Xenopus Anterior Development Through Apoptotic Pathways. , Schreiner C, Kernl B, Dietmann P, Riegger RJ, Kühl M , Kühl SJ ., Front Cell Dev Biol. January 1, 2022; 10 777121.
Developmental and Injury-induced Changes in DNA Methylation in Regenerative versus Non-regenerative Regions of the Vertebrate Central Nervous System. , Reverdatto S, Prasad A, Belrose JL, Zhang X, Sammons MA, Gibbs KM , Szaro BG ., BMC Genomics. January 4, 2022; 23 (1): 2.
Systematic mapping of rRNA 2'-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis. , Delhermite J , Tafforeau L, Sharma S, Marchand V, Wacheul L, Lattuca R, Desiderio S, Motorin Y, Bellefroid E , Lafontaine DLJ ., PLoS Genet. January 18, 2022; 18 (1): e1010012.
Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development. , Sun J, Yoon J, Lee M, Lee HK , Hwang YS, Daar IO ., Cell Rep. February 1, 2022; 38 (5): 110312.
Functions of block of proliferation 1 during anterior development in Xenopus laevis. , Gärtner C, Meßmer A, Dietmann P, Kühl M , Kühl SJ ., PLoS One. August 2, 2022; 17 (8): e0273507.
Engraftment of Allotransplanted Tumor Cells in Adult rag2 Mutant Xenopus tropicalis. , Tulkens D, Dimitrakopoulou D, Boelens M, Van Nieuwenhuysen T, Demuynck S, Toussaint W, Creytens D, Van Vlierberghe P, Vleminckx K , Vleminckx K ., Cancers (Basel). September 20, 2022; 14 (19):
Disruption of tp53 leads to cutaneous nevus and melanoma formation in Xenopus tropicalis. , Ran R, Li L, Shi Z, Liu G , Jiang H, Fang L, Xu T, Huang J, Chen W, Chen Y ., Mol Oncol. October 1, 2022; 16 (19): 3554-3567.
Activation of P53 pathway contributes to Xenopus hybrid inviability. , Shi Z, Liu G , Jiang H, Shi S, Zhang X, Deng Y, Chen Y ., Proc Natl Acad Sci U S A. May 23, 2023; 120 (21): e2303698120.