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Summary Expression Phenotypes Gene Literature (151) GO Terms (5) Nucleotides (57) Proteins (40) Interactants (234) Wiki
XB-GENEPAGE-949326

Papers associated with grin2b



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Single-channel conductances of NMDA receptors expressed from cloned cDNAs: comparison with native receptors., Stern P, Béhé P, Schoepfer R, Colquhoun D., Proc Biol Sci. December 22, 1992; 250 (1329): 271-7.

Subunit-specific block of cloned NMDA receptors by argiotoxin636., Raditsch M, Ruppersberg JP, Kuner T, Günther W, Schoepfer R, Seeburg PH, Jahn W, Witzemann V., FEBS Lett. June 7, 1993; 324 (1): 63-6.

Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors., Williams K., Mol Pharmacol. October 1, 1993; 44 (4): 851-9.

Ethanol inhibits glutamate-induced currents in heteromeric NMDA receptor subtypes., Kuner T, Schoepfer R, Korpi ER., Neuroreport. December 13, 1993; 5 (3): 297-300.

Glycine-glutamate interactions at the NMDA receptor: role of cysteine residues., Laube B, Kuryatov A, Kuhse J, Betz H., FEBS Lett. December 13, 1993; 335 (3): 331-4.

Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by NR2 subunits., Williams K, Zappia AM, Pritchett DB, Shen YM, Molinoff PB., Mol Pharmacol. May 1, 1994; 45 (5): 803-9.

Cloning, functional coexpression, and pharmacological characterisation of human cDNAs encoding NMDA receptor NR1 and NR2A subunits., Le Bourdellès B, Wafford KA, Kemp JA, Marshall G, Bain C, Wilcox AS, Sikela JM, Whiting PJ., J Neurochem. June 1, 1994; 62 (6): 2091-8.

Mechanisms influencing stimulatory effects of spermine at recombinant N-methyl-D-aspartate receptors., Williams K., Mol Pharmacol. July 1, 1994; 46 (1): 161-8.

Subunit-specific potentiation of recombinant N-methyl-D-aspartate receptors by histamine., Williams K., Mol Pharmacol. September 1, 1994; 46 (3): 531-41.

The molecular basis of NMDA receptor subtypes: native receptor diversity is predicted by subunit composition., Buller AL, Larson HC, Schneider BE, Beaton JA, Morrisett RA, Monaghan DT., J Neurosci. September 1, 1994; 14 (9): 5471-84.

Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptor., Sullivan JM, Traynelis SF, Chen HS, Escobar W, Heinemann SF, Lipton SA., Neuron. October 1, 1994; 13 (4): 929-36.

Spermine potentiation of recombinant N-methyl-D-aspartate receptors is affected by subunit composition., Zhang L, Zheng X, Paupard MC, Wang AP, Santchi L, Friedman LK, Zukin RS, Bennett MV., Proc Natl Acad Sci U S A. November 8, 1994; 91 (23): 10883-7.

Pharmacological properties of recombinant N-methyl-D-aspartate (NMDA) receptors containing the epsilon 4 (NR2D) subunit., Williams K., Neurosci Lett. January 30, 1995; 184 (3): 181-4.

Antagonist properties of polyamines and bis(ethyl)polyamines at N-methyl-D-aspartate receptors., Igarashi K, Williams K., J Pharmacol Exp Ther. March 1, 1995; 272 (3): 1101-9.

Block of the N-methyl-D-aspartate receptor by phencyclidine-like drugs is influenced by alternative splicing., Rodríguez-Paz JM, Anantharam V, Treistman SN., Neurosci Lett. May 12, 1995; 190 (3): 147-50.

Ethanol inhibition of recombinant heteromeric NMDA channels in the presence and absence of modulators., Chu B, Anantharam V, Treistman SN., J Neurochem. July 1, 1995; 65 (1): 140-8.

Glycine modulates ethanol inhibition of heteromeric N-methyl-D-aspartate receptors expressed in Xenopus oocytes., Buller AL, Larson HC, Morrisett RA, Monaghan DT., Mol Pharmacol. October 1, 1995; 48 (4): 717-23.

Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain., Sucher NJ, Akbarian S, Chi CL, Leclerc CL, Awobuluyi M, Deitcher DL, Wu MK, Yuan JP, Jones EG, Lipton SA., J Neurosci. October 1, 1995; 15 (10): 6509-20.

Glycine-independent and subunit-specific potentiation of NMDA responses by extracellular Mg2+., Paoletti P, Neyton J, Ascher P., Neuron. November 1, 1995; 15 (5): 1109-20.

An acidic amino acid in the N-methyl-D-aspartate receptor that is important for spermine stimulation., Williams K, Kashiwagi K, Fukuchi J, Igarashi K., Mol Pharmacol. December 1, 1995; 48 (6): 1087-98.

Antagonist properties of the stereoisomers of ifenprodil at NR1A/NR2A and NR1A/NR2B subtypes of the NMDA receptor expressed in Xenopus oocytes., Avenet P, Léonardon J, Besnard F, Graham D, Frost J, Depoortere H, Langer SZ, Scatton B., Eur J Pharmacol. January 25, 1996; 296 (2): 209-13.

The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits., de Carvalho LP, Bochet P, Rossier J., Neurochem Int. April 1, 1996; 28 (4): 445-52.

An aspartate residue in the extracellular loop of the N-methyl-D-aspartate receptor controls sensitivity to spermine and protons., Kashiwagi K, Fukuchi J, Chao J, Igarashi K, Williams K., Mol Pharmacol. June 1, 1996; 49 (6): 1131-41.

Multiple structural elements determine subunit specificity of Mg2+ block in NMDA receptor channels., Kuner T, Schoepfer R., J Neurosci. June 1, 1996; 16 (11): 3549-58.

Alternative splicing of the NMDAR1 subunit affects modulation by calcium., Koltchine VV, Anantharam V, Bayley H, Treistman SN., Brain Res Mol Brain Res. July 1, 1996; 39 (1-2): 99-108.

Cloning and functional characterization of human heteromeric N-methyl-D-aspartate receptors., Hess SD, Daggett LP, Crona J, Deal C, Lu CC, Urrutia A, Chavez-Noriega L, Ellis SB, Johnson EC, Veliçelebi G., J Pharmacol Exp Ther. August 1, 1996; 278 (2): 808-16.

Use of subunit-specific antisense oligodeoxynucleotides to define developmental changes in the properties of N-methyl-D-aspartate receptors., Zhong J, Gribkoff VK, Molinoff PB., Mol Pharmacol. September 1, 1996; 50 (3): 631-8.

Subtype-selective inhibition of N-methyl-D-aspartate receptors by haloperidol., Ilyin VI, Whittemore ER, Guastella J, Weber E, Woodward RM., Mol Pharmacol. December 1, 1996; 50 (6): 1541-50.

Subconductance states of a mutant NMDA receptor channel kinetics, calcium, and voltage dependence., Premkumar LS, Qin F, Auerbach A., J Gen Physiol. February 1, 1997; 109 (2): 181-9.      

NR1 and NR2 subunit contributions to N-methyl-D-aspartate receptor channel blocker pharmacology., Monaghan DT, Larsen H., J Pharmacol Exp Ther. February 1, 1997; 280 (2): 614-20.

Pharmacological heterogeneity of NMDA receptors: characterization of NR1a/NR2D heteromers expressed in Xenopus oocytes., Buller AL, Monaghan DT., Eur J Pharmacol. February 5, 1997; 320 (1): 87-94.

Antagonist properties of eliprodil and other NMDA receptor antagonists at rat NR1A/NR2A and NR1A/NR2B receptors expressed in Xenopus oocytes., Avenet P, Léonardon J, Besnard F, Graham D, Depoortere H, Scatton B., Neurosci Lett. February 21, 1997; 223 (2): 133-6.

Influence of extracellular pH on inhibition by ifenprodil at N-methyl-D-aspartate receptors in Xenopus oocytes., Pahk AJ, Williams K., Neurosci Lett. March 28, 1997; 225 (1): 29-32.

Antagonism of N-methyl-D-aspartate receptors by sigma site ligands: potency, subtype-selectivity and mechanisms of inhibition., Whittemore ER, Ilyin VI, Woodward RM., J Pharmacol Exp Ther. July 1, 1997; 282 (1): 326-38.

High-affinity zinc inhibition of NMDA NR1-NR2A receptors., Paoletti P, Ascher P, Neyton J., J Neurosci. August 1, 1997; 17 (15): 5711-25.

Benzyl-polyamines: novel, potent N-methyl-D-aspartate receptor antagonists., Igarashi K, Shirahata A, Pahk AJ, Kashiwagi K, Williams K., J Pharmacol Exp Ther. November 1, 1997; 283 (2): 533-40.

Stoichiometry of recombinant N-methyl-D-aspartate receptor channels inferred from single-channel current patterns., Premkumar LS, Auerbach A., J Gen Physiol. November 1, 1997; 110 (5): 485-502.                        

Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro., Fischer G, Mutel V, Trube G, Malherbe P, Kew JN, Mohacsi E, Heitz MP, Kemp JA., J Pharmacol Exp Ther. December 1, 1997; 283 (3): 1285-92.

State-dependent NMDA receptor antagonism by Ro 8-4304, a novel NR2B selective, non-competitive, voltage-independent antagonist., Kew JN, Trube G, Kemp JA., Br J Pharmacol. February 1, 1998; 123 (3): 463-72.

Antagonist properties of a phosphono isoxazole amino acid at glutamate R1-4 (R,S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid receptor subtypes., Wahl P, Anker C, Traynelis SF, Egebjerg J, Rasmussen JS, Krogsgaard-Larsen P, Madsen U., Mol Pharmacol. March 1, 1998; 53 (3): 590-6.

Evidence for a tetrameric structure of recombinant NMDA receptors., Laube B, Kuhse J, Betz H., J Neurosci. April 15, 1998; 18 (8): 2954-61.

Differentiation of glycine antagonist sites of N-methyl-D-aspartate receptor subtypes. Preferential interaction of CGP 61594 with NR1/2B receptors., Honer M, Benke D, Laube B, Kuhse J, Heckendorn R, Allgeier H, Angst C, Monyer H, Seeburg PH, Betz H, Mohler H., J Biol Chem. May 1, 1998; 273 (18): 11158-63.

Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit., Traynelis SF, Burgess MF, Zheng F, Lyuboslavsky P, Powers JL., J Neurosci. August 15, 1998; 18 (16): 6163-75.

Structure-activity relationships for a series of bis(phenylalkyl)amines: potent subtype-selective inhibitors of N-methyl-D-aspartate receptors., Tamiz AP, Whittemore ER, Zhou ZL, Huang JC, Drewe JA, Chen JC, Cai SX, Weber E, Woodward RM, Keana JF., J Med Chem. August 27, 1998; 41 (18): 3499-506.

Protein kinase C modulation of recombinant NMDA receptor currents: roles for the C-terminal C1 exon and calcium ions., Logan SM, Rivera FE, Leonard JP., J Neurosci. February 1, 1999; 19 (3): 974-86.

Subtype-selective antagonism of N-methyl-D-aspartate receptors by felbamate: insights into the mechanism of action., Kleckner NW, Glazewski JC, Chen CC, Moscrip TD., J Pharmacol Exp Ther. May 1, 1999; 289 (2): 886-94.

A regulatory domain (R1-R2) in the amino terminus of the N-methyl-D-aspartate receptor: effects of spermine, protons, and ifenprodil, and structural similarity to bacterial leucine/isoleucine/valine binding protein., Masuko T, Kashiwagi K, Kuno T, Nguyen ND, Pahk AJ, Fukuchi J, Igarashi K, Williams K., Mol Pharmacol. June 1, 1999; 55 (6): 957-69.

NMDA receptor subunit gene expression in the rat brain: a quantitative analysis of endogenous mRNA levels of NR1Com, NR2A, NR2B, NR2C, NR2D and NR3A., Goebel DJ, Poosch MS., Brain Res Mol Brain Res. June 8, 1999; 69 (2): 164-70.

Structure-activity relationship of N-(phenylalkyl)cinnamides as novel NR2B subtype-selective NMDA receptor antagonists., Tamiz AP, Cai SX, Zhou ZL, Yuen PW, Schelkun RM, Whittemore ER, Weber E, Woodward RM, Keana JF., J Med Chem. August 26, 1999; 42 (17): 3412-20.

Differing effects of N-methyl-D-aspartate receptor subtype selective antagonists on dyskinesias in levodopa-treated 1-methyl-4-phenyl-tetrahydropyridine monkeys., Blanchet PJ, Konitsiotis S, Whittemore ER, Zhou ZL, Woodward RM, Chase TN., J Pharmacol Exp Ther. September 1, 1999; 290 (3): 1034-40.

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