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Cysteine-scanning mutagenesis and substituted cysteine accessibility analysis of transmembrane segment 4 of the Glut1 glucose transporter. , Mueckler M, Makepeace C., J Biol Chem. November 25, 2005; 280 (47): 39562-8.
Microarray-based identification of VegT targets in Xenopus. , Taverner NV, Kofron M , Kofron M , Shin Y , Kabitschke C, Gilchrist MJ , Wylie C , Cho KW , Heasman J , Smith JC ., Mech Dev. March 1, 2005; 122 (3): 333-54.
6-Bromo-6-deoxy-L-ascorbic acid: an ascorbate analog specific for Na+-dependent vitamin C transporter but not glucose transporter pathways. , Corpe CP, Lee JH , Lee JH , Kwon O, Eck P, Narayanan J, Kirk KL, Levine M., J Biol Chem. February 18, 2005; 280 (7): 5211-20.
A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity. , Hertel J, Struthers H, Horj CB, Hruz PW., J Biol Chem. December 31, 2004; 279 (53): 55147-52.
Transmembrane segment 3 of the Glut1 glucose transporter is an outer helix. , Mueckler M, Roach W, Makepeace C., J Biol Chem. November 5, 2004; 279 (45): 46876-81.
Relative proximity and orientation of helices 4 and 8 of the GLUT1 glucose transporter. , Alisio A, Mueckler M., J Biol Chem. June 18, 2004; 279 (25): 26540-5.
Analysis of transmembrane segment 8 of the GLUT1 glucose transporter by cysteine-scanning mutagenesis and substituted cysteine accessibility. , Mueckler M, Makepeace C., J Biol Chem. March 12, 2004; 279 (11): 10494-9.
Cysteine-scanning mutagenesis of transmembrane segment 1 of glucose transporter GLUT1: extracellular accessibility of helix positions. , Heinze M, Monden I, Keller K., Biochemistry. February 3, 2004; 43 (4): 931-6.
Functional studies of threonine 310 mutations in Glut1: T310I is pathogenic, causing Glut1 deficiency. , Wang D, Pascual JM, Iserovich P, Yang H, Ma L, Kuang K, Zuniga FA, Sun RP, Swaroop KM, Fischbarg J, De Vivo DC., J Biol Chem. December 5, 2003; 278 (49): 49015-21.
Functional consequences of an in vivo mutation in exon 10 of the human GLUT1 gene. , Lange P, Gertsen E, Monden I, Klepper J, Keller K., FEBS Lett. December 4, 2003; 555 (2): 274-8.
Downregulation of the Na(+)- D-glucose cotransporter SGLT1 by protein RS1 ( RSC1A1) is dependent on dynamin and protein kinase C. , Veyhl M, Wagner CA, Gorboulev V, Schmitt BM, Lang F , Koepsell H., J Membr Biol. November 1, 2003; 196 (1): 71-81.
Synthesis and biologic evaluation of (11)c-methyl-d-glucoside, a tracer of the sodium-dependent glucose transporters. , Bormans GM, Van Oosterwyck G, De Groot TJ, Veyhl M, Mortelmans L, Verbruggen AM, Koepsell H., J Nucl Med. July 1, 2003; 44 (7): 1075-81.
Validation of the hexose transporter of Plasmodium falciparum as a novel drug target. , Joet T, Eckstein-Ludwig U, Morin C, Krishna S., Proc Natl Acad Sci U S A. June 24, 2003; 100 (13): 7476-9.
Mutational analysis of the hexose transporter of Plasmodium falciparum and development of a three-dimensional model. , Manning SK, Woodrow C, Zuniga FA, Iserovich P, Fischbarg J, Louw AI, Krishna S., J Biol Chem. August 23, 2002; 277 (34): 30942-9.
Changes in glucose transport and water permeability resulting from the T310I pathogenic mutation in Glut1 are consistent with two transport channels per monomer. , Iserovich P, Wang D, Ma L, Yang H, Zuniga FA, Pascual JM, Kuang K, De Vivo DC, Fischbarg J., J Biol Chem. August 23, 2002; 277 (34): 30991-7.
GLUT2 is a high affinity glucosamine transporter. , Uldry M, Ibberson M, Hosokawa M, Thorens B., FEBS Lett. July 31, 2002; 524 (1-3): 199-203.
Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations. , Murata H, Hruz PW, Mueckler M., AIDS. April 12, 2002; 16 (6): 859-63.
Analysis of transmembrane segment 10 of the Glut1 glucose transporter by cysteine-scanning mutagenesis and substituted cysteine accessibility. , Mueckler M, Makepeace C., J Biol Chem. February 1, 2002; 277 (5): 3498-503.
The large cytoplasmic loop of the glucose transporter GLUT1 is an essential structural element for function. , Monden I, Olsowski A, Krause G, Keller K., Biol Chem. November 1, 2001; 382 (11): 1551-8.
Rainbow trout glucose transporter (OnmyGLUT1): functional assessment in Xenopus laevis oocytes and expression in fish embryos. , Teerijoki H, Krasnov A, Gorodilov Y, Krishna S, Mölsä H., J Exp Biol. August 1, 2001; 204 (Pt 15): 2667-73.
The predicted ATP-binding domains in the hexose transporter GLUT1 critically affect transporter activity. , Liu Q, Vera JC, Peng H , Golde DW., Biochemistry. July 3, 2001; 40 (26): 7874-81.
Functional consequences of the autosomal dominant G272A mutation in the human GLUT1 gene. , Klepper J, Monden I, Guertsen E, Voit T, Willemsen M, Keller K., FEBS Lett. June 1, 2001; 498 (1): 104-9.
Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1. , Dawson PA, Mychaleckyj JC, Fossey SC, Mihic SJ, Craddock AL, Bowden DW., Mol Genet Metab. January 1, 2001; 74 (1-2): 186-99.
Dehydroascorbic acid transport by GLUT4 in Xenopus oocytes and isolated rat adipocytes. , Rumsey SC, Daruwala R, Al-Hasani H, Zarnowski MJ, Simpson IA, Levine M., J Biol Chem. September 8, 2000; 275 (36): 28246-53.
Cysteine-scanning mutagenesis of transmembrane segment 11 of the GLUT1 facilitative glucose transporter. , Hruz PW, Mueckler MM., Biochemistry. August 8, 2000; 39 (31): 9367-72.
The mechanism of insulin resistance caused by HIV protease inhibitor therapy. , Murata H, Hruz PW, Mueckler M., J Biol Chem. July 7, 2000; 275 (27): 20251-4.
Cysteine scanning mutagenesis of helices 2 and 7 in GLUT1 identifies an exofacial cleft in both transmembrane segments. , Olsowski A, Monden I, Krause G, Keller K., Biochemistry. March 14, 2000; 39 (10): 2469-74.
Constitutively active mitogen-activated protein kinase kinase increases GLUT1 expression and recruits both GLUT1 and GLUT4 at the cell surface in 3T3-L1 adipocytes. , Yamamoto Y, Yoshimasa Y, Koh M, Suga J, Masuzaki H, Ogawa Y, Hosoda K, Nishimura H, Watanabe Y, Inoue G, Nakao K., Diabetes. March 1, 2000; 49 (3): 332-9.
GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues. , Ibberson M, Uldry M, Thorens B., J Biol Chem. February 18, 2000; 275 (7): 4607-12.
Cysteine-scanning mutagenesis of transmembrane segment 7 of the GLUT1 glucose transporter. , Hruz PW, Mueckler MM., J Biol Chem. December 17, 1999; 274 (51): 36176-80.
Selective expression of the large neutral amino acid transporter at the blood- brain barrier. , Boado RJ, Li JY, Nagaya M, Zhang C, Pardridge WM., Proc Natl Acad Sci U S A. October 12, 1999; 96 (21): 12079-84.
A conserved amino acid motif (R-X-G-R-R) in the Glut1 glucose transporter is an important determinant of membrane topology. , Sato M, Mueckler M., J Biol Chem. August 27, 1999; 274 (35): 24721-5.
Specificity of ascorbate analogs for ascorbate transport. Synthesis and detection of [(125)I]6-deoxy-6-iodo-L-ascorbic acid and characterization of its ascorbate-specific transport properties. , Rumsey SC, Welch RW, Garraffo HM, Ge P, Lu SF, Crossman AT, Kirk KL, Levine M., J Biol Chem. August 13, 1999; 274 (33): 23215-22.
Transmembrane segment 5 of the Glut1 glucose transporter is an amphipathic helix that forms part of the sugar permeation pathway. , Mueckler M, Makepeace C., J Biol Chem. April 16, 1999; 274 (16): 10923-6.
Cysteine-scanning mutagenesis of flanking regions at the boundary between external loop I or IV and transmembrane segment II or VII in the GLUT1 glucose transporter. , Olsowski A, Monden I, Keller K., Biochemistry. July 28, 1998; 37 (30): 10738-45.
Identification of an amino acid residue that lies between the exofacial vestibule and exofacial substrate-binding site of the Glut1 sugar permeation pathway. , Mueckler M, Makepeace C., J Biol Chem. November 28, 1997; 272 (48): 30141-6.
Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid. , Rumsey SC, Kwon O, Xu GW, Burant CF, Simpson I, Levine M., J Biol Chem. July 25, 1997; 272 (30): 18982-9.
Heterologous expression of rab4 reduces glucose transport and GLUT4 abundance at the cell surface in oocytes. , Mora S, Monden I, Zorzano A, Keller K., Biochem J. June 1, 1997; 324 ( Pt 2) 455-9.
C-terminal mutations that alter the turnover number for 3-O-methylglucose transport by GLUT1 and GLUT4. , Dauterive R, Laroux S, Bunn RC, Chaisson A, Sanson T, Reed BC., J Biol Chem. May 10, 1996; 271 (19): 11414-21.
Insulin and insulin-like growth factor I ( IGF-I) stimulate GLUT4 glucose transporter translocation in Xenopus oocytes. , Mora S, Kaliman P, Chillarón J, Testar X, Palacín M, Zorzano A., Biochem J. October 1, 1995; 311 ( Pt 1) 59-65.
From triple cysteine mutants to the cysteine-less glucose transporter GLUT1: a functional analysis. , Wellner M, Monden I, Keller K., FEBS Lett. August 14, 1995; 370 (1-2): 19-22.
Role of the C-terminal tail of the GLUT1 glucose transporter in its expression and function in Xenopus laevis oocytes. , Due AD, Qu ZC, Thomas JM, Buchs A, Powers AC, May JM., Biochemistry. April 25, 1995; 34 (16): 5462-71.
A "cysteineless" GLUT1 glucose transporter has normal function when expressed in Xenopus oocytes. , Due AD, Cook JA, Fletcher SJ, Qu ZC, Powers AC, May JM., Biochem Biophys Res Commun. March 17, 1995; 208 (2): 590-6.
Functional consequences of proline mutations in the putative transmembrane segments 6 and 10 of the glucose transporter GLUT1. , Wellner M, Monden I, Mueckler MM, Keller K., Eur J Biochem. January 15, 1995; 227 (1-2): 454-8.
Discrete structural domains determine differential endoplasmic reticulum to Golgi transit times for glucose transporter isoforms. , Hresko RC, Murata H, Marshall BA, Mueckler M., J Biol Chem. December 23, 1994; 269 (51): 32110-9.
Characterization of glucose transport and cloning of a hexose transporter gene in Trypanosoma cruzi. , Tetaud E, Bringaud F, Chabas S, Barrett MP, Baltz T., Proc Natl Acad Sci U S A. August 16, 1994; 91 (17): 8278-82.
Glutamine 161 of Glut1 glucose transporter is critical for transport activity and exofacial ligand binding. , Mueckler M, Weng W, Kruse M., J Biol Chem. August 12, 1994; 269 (32): 20533-8.
Production of functional GLUT1 by co-expression of N- and C-terminal half molecules in Xenopus oocytes. , Preston RA, Sami AJ, Charalambous BM, Baldwin SA., Biochem Soc Trans. August 1, 1994; 22 (3): 276S.
The role of cysteine residues in glucose-transporter- GLUT1-mediated transport and transport inhibition. , Wellner M, Monden I, Keller K., Biochem J. May 1, 1994; 299 ( Pt 3) 813-7.
Evidence that facilitative glucose transporters may fold as beta-barrels. , Fischbarg J, Cheung M, Czegledy F, Li J, Iserovich P, Kuang K, Hubbard J, Garner M, Rosen OM, Golde DW., Proc Natl Acad Sci U S A. December 15, 1993; 90 (24): 11658-62.