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Summary Expression Phenotypes Gene Literature (34) GO Terms (5) Nucleotides (152) Proteins (59) Interactants (211) Wiki
XB-GENEPAGE-484247

Papers associated with acvr2b



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Cloning of a second type of activin receptor and functional characterization in Xenopus embryos., Mathews LS, Vale WW, Kintner CR., Science. March 27, 1992; 255 (5052): 1702-5.

Embryonic expression and functional analysis of a Xenopus activin receptor., Hemmati-Brivanlou A, Wright DA, Melton DA., Dev Dyn. May 1, 1992; 194 (1): 1-11.        

A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos., Hemmati-Brivanlou A, Melton DA., Nature. October 15, 1992; 359 (6396): 609-14.

Activin receptors: cellular signalling by receptor serine kinases., Zimmerman CM, Mathews LS., Biochem Soc Symp. January 1, 1996; 62 25-38.

A truncated FGF receptor blocks neural induction by endogenous Xenopus inducers., Launay C, Fromentoux V, Shi DL, Boucaut JC., Development. March 1, 1996; 122 (3): 869-80.                

Differential effects on Xenopus development of interference with type IIA and type IIB activin receptors., New HV, Kavka AI, Smith JC, Green JB., Mech Dev. January 1, 1997; 61 (1-2): 175-86.          

Inhibitory control of neural differentiation in mammalian cells., Hoodless PA, Hemmati-Brivanlou A., Dev Genes Evol. May 1, 1997; 207 (1): 19-28.

Bovine activin receptor type IIB messenger ribonucleic acid displays alternative splicing involving a sequence homologous to Src-homology 3 domain binding sites., Ethier JF, Lussier JG, Silversides DW., Endocrinology. June 1, 1997; 138 (6): 2425-34.

The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse., Oh SP, Li E., Genes Dev. July 15, 1997; 11 (14): 1812-26.

Cloning and characterization of goldfish activin type IIB receptor., Ge W, Tanaka M, Yoshikuni M, Eto Y, Nagahama Y., J Mol Endocrinol. August 1, 1997; 19 (1): 47-57.

Activin has direct long-range signalling activity and can form a concentration gradient by diffusion., McDowell N, Zorn AM, Crease DJ, Gurdon JB., Curr Biol. September 1, 1997; 7 (9): 671-81.          

XBMPRII, a novel Xenopus type II receptor mediating BMP signaling in embryonic tissues., Frisch A, Wright CV., Development. February 1, 1998; 125 (3): 431-42.                  

Left-right axis malformations associated with mutations in ACVR2B, the gene for human activin receptor type IIB., Kosaki R, Gebbia M, Kosaki K, Lewin M, Bowers P, Towbin JA, Casey B., Am J Med Genet. January 1, 1999; 82 (1): 70-6.

Anterior endomesoderm specification in Xenopus by Wnt/beta-catenin and TGF-beta signalling pathways., Zorn AM, Butler K, Gurdon JB., Dev Biol. May 15, 1999; 209 (2): 282-97.                    

Cloning of zebrafish activin type IIB receptor (ActRIIB) cDNA and mRNA expression of ActRIIB in embryos and adult tissues., Garg RR, Bally-Cuif L, Lee SE, Gong Z, Ni X, Hew CL, Peng C., Mol Cell Endocrinol. July 20, 1999; 153 (1-2): 169-81.

The type II activin receptors are essential for egg cylinder growth, gastrulation, and rostral head development in mice., Song J, Oh SP, Schrewe H, Nomura M, Lei H, Okano M, Gridley T, Li E., Dev Biol. September 1, 1999; 213 (1): 157-69.

The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development., Reissmann E, Jörnvall H, Blokzijl A, Andersson O, Chang C, Minchiotti G, Persico MG, Ibáñez CF, Brivanlou AH., Genes Dev. August 1, 2001; 15 (15): 2010-22.                

Expression cloning of Xenopus Os4, an evolutionarily conserved gene, which induces mesoderm and dorsal axis., Zohn IE, Brivanlou AH., Dev Biol. November 1, 2001; 239 (1): 118-31.                    

Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion., Sakuma R, Ohnishi Yi Y, Meno C, Fujii H, Juan H, Takeuchi J, Ogura T, Li E, Miyazono K, Hamada H., Genes Cells. April 1, 2002; 7 (4): 401-12.

A novel function for Hedgehog signalling in retinal pigment epithelium differentiation., Perron M, Boy S, Amato MA, Viczian A, Koebernick K, Pieler T, Harris WA., Development. April 1, 2003; 130 (8): 1565-77.                                  

Arrestin migrates in photoreceptors in response to light: a study of arrestin localization using an arrestin-GFP fusion protein in transgenic frogs., Peterson JJ, Tam BM, Moritz OL, Shelamer CL, Dugger DR, McDowell JH, Hargrave PA, Papermaster DS, Smith WC., Exp Eye Res. May 1, 2003; 76 (5): 553-63.          

Nodal-dependent Cripto signaling promotes cardiomyogenesis and redirects the neural fate of embryonic stem cells., Parisi S, D'Andrea D, Lago CT, Adamson ED, Persico MG, Minchiotti G., J Cell Biol. October 27, 2003; 163 (2): 303-14.                    

Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors., Cheng SK, Olale F, Brivanlou AH, Schier AF., PLoS Biol. February 1, 2004; 2 (2): E30.                  

DRAGON, a bone morphogenetic protein co-receptor., Samad TA, Rebbapragada A, Bell E, Zhang Y, Zhang Y, Sidis Y, Jeong SJ, Campagna JA, Perusini S, Fabrizio DA, Schneyer AL, Lin HY, Brivanlou AH, Attisano L, Woolf CJ., J Biol Chem. April 8, 2005; 280 (14): 14122-9.                  

BMP-3 is a novel inhibitor of both activin and BMP-4 signaling in Xenopus embryos., Gamer LW, Nove J, Levin M, Rosen V., Dev Biol. September 1, 2005; 285 (1): 156-68.              

The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo., Chen C, Ware SM, Sato A, Houston-Hawkins DE, Habas R, Matzuk MM, Shen MM, Brown CW., Development. January 1, 2006; 133 (2): 319-29.              

Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development., Andersson O, Bertolino P, Ibáñez CF., Dev Biol. November 15, 2007; 311 (2): 500-11.

Rab5-mediated endocytosis of activin is not required for gene activation or long-range signalling in Xenopus., Hagemann AI, Xu X, Nentwich O, Hyvonen M, Smith JC., Development. August 1, 2009; 136 (16): 2803-13.                

The human PDZome: a gateway to PSD95-Disc large-zonula occludens (PDZ)-mediated functions., Belotti E, Polanowska J, Daulat AM, Audebert S, Thomé V, Lissitzky JC, Lembo F, Blibek K, Omi S, Lenfant N, Gangar A, Montcouquiol M, Santoni MJ, Sebbagh M, Aurrand-Lions M, Angers S, Kodjabachian L, Reboul J, Borg JP., Mol Cell Proteomics. September 1, 2013; 12 (9): 2587-603.                  

Biological and biochemical properties of two Xenopus laevis N-acetylgalactosaminyltransferases with contrasting roles in embryogenesis., Voglmeir J, Laurent N, Flitsch SL, Oelgeschläger M, Wilson IB., Comp Biochem Physiol B Biochem Mol Biol. February 1, 2015; 180 40-7.          

TGF-β Signaling Regulates the Differentiation of Motile Cilia., Tözser J, Earwood R, Kato A, Brown J, Tanaka K, Didier R, Megraw TL, Blum M, Kato Y., Cell Rep. May 19, 2015; 11 (7): 1000-7.                

Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage., Kirmizitas A, Meiklejohn S, Ciau-Uitz A, Stephenson R, Patient R., Proc Natl Acad Sci U S A. June 6, 2017; 114 (23): 5814-5821.                    

Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects., Galgoczi S, Ruzo A, Markopoulos C, Yoney A, Phan-Everson T, Li S, Haremaki T, Metzger JJ, Etoc F, Brivanlou AH., Development. October 1, 2021; 148 (19):               

Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd., Lee H, Lee H, Sun R, Niehrs C., J Biol Chem. February 1, 2022; 298 (2): 101586.                

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