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Summary Expression Phenotypes Gene Literature (209) GO Terms (7) Nucleotides (115) Proteins (41) Interactants (1134) Wiki
XB-GENEPAGE-492664

Papers associated with rax



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Developmental role of plk4 in Xenopus laevis and Danio rerio: implications for Seckel Syndrome., Rapchak CE, Patel N, Hudson J, Crawford M., Biochem Cell Biol. August 1, 2015; 93 (4): 396-404.  

The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway., Luehders K, Sasai N, Davaapil H, Kurosawa-Yoshida M, Hiura H, Brah T, Ohnuma S., Development. October 1, 2015; 142 (19): 3351-61.                              

NF2/Merlin is required for the axial pattern formation in the Xenopus laevis embryo., Zhu X, Min Z, Tan R, Tao Q, Tao Q., Mech Dev. November 1, 2015; 138 Pt 3 305-12.                

Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients., Nakayama T, Fisher M, Fisher M, Nakajima K, Odeleye AO, Zimmerman KB, Fish MB, Yaoita Y, Chojnowski JL, Lauderdale JD, Netland PA, Grainger RM., Dev Biol. December 15, 2015; 408 (2): 328-44.                              

Platelet derived growth factor B gene expression in the Xenopus laevis developing central nervous system., Giannetti K, Corsinovi D, Rossino C, Appolloni I, Malatesta P, Ori M., Int J Dev Biol. January 1, 2016; 60 (4-6): 175-9.      

Noggin4 is a long-range inhibitor of Wnt8 signalling that regulates head development in Xenopus laevis., Eroshkin FM, Nesterenko AM, Borodulin AV, Martynova NY, Ermakova GV, Gyoeva FK, Orlov EE, Belogurov AA, Lukyanov KA, Bayramov AV, Zaraisky AG., Sci Rep. January 22, 2016; 6 23049.                                                            

Tbx3 represses bmp4 expression and, with Pax6, is required and sufficient for retina formation., Motahari Z, Martinez-De Luna RI, Viczian AS, Zuber ME., Development. October 1, 2016; 143 (19): 3560-3572.                                      

Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling., Jin Z, Schwend T, Fu J, Bao Z, Liang J, Zhao H, Mei W, Yang J., Development. November 1, 2016; 143 (21): 3944-3955.                        

Autoregulation of retinal homeobox (rax) gene promoter activity through a highly conserved genomic element., Kelly LE, Martinez-De Luna RI, El-Hodiri HM., Genesis. November 1, 2016; 54 (11): 562-567.      

MarvelD3 regulates the c-Jun N-terminal kinase pathway during eye development in Xenopus., Vacca B, Sanchez-Heras E, Steed E, Balda MS, Ohnuma SI, Sasai N, Mayor R, Matter K., Biol Open. November 15, 2016; 5 (11): 1631-1641.                          

An Epha4/Sipa1l3/Wnt pathway regulates eye development and lens maturation., Rothe M, Kanwal N, Dietmann P, Seigfried FA, Hempel A, Schütz D, Reim D, Engels R, Linnemann A, Schmeisser MJ, Bockmann J, Kühl M, Boeckers TM, Kühl SJ., Development. January 15, 2017; 144 (2): 321-333.                              

De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development., Gordon CT, Xue S, Yigit G, Filali H, Chen K, Rosin N, Yoshiura KI, Oufadem M, Beck TJ, McGowan R, Magee AC, Altmüller J, Dion C, Thiele H, Gurzau AD, Nürnberg P, Meschede D, Mühlbauer W, Okamoto N, Varghese V, Irving R, Sigaudy S, Williams D, Ahmed SF, Bonnard C, Kong MK, Ratbi I, Fejjal N, Fikri M, Elalaoui SC, Reigstad H, Bole-Feysot C, Nitschké P, Ragge N, Lévy N, Tunçbilek G, Teo AS, Cunningham ML, Sefiani A, Kayserili H, Murphy JM, Chatdokmaiprai C, Hillmer AM, Wattanasirichaigoon D, Lyonnet S, Magdinier F, Javed A, Blewitt ME, Amiel J, Wollnik B, Reversade B., Nat Genet. February 1, 2017; 49 (2): 249-255.        

The Nedd4 binding protein 3 is required for anterior neural development in Xenopus laevis., Kiem LM, Dietmann P, Linnemann A, Schmeisser MJ, Kühl SJ., Dev Biol. March 1, 2017; 423 (1): 66-76.                            

Frizzled 3 acts upstream of Alcam during embryonic eye development., Seigfried FA, Cizelsky W, Pfister AS, Dietmann P, Walther P, Kühl M, Kühl SJ., Dev Biol. June 1, 2017; 426 (1): 69-83.                        

Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula., Ding Y, Colozza G, Zhang K, Moriyama Y, Ploper D, Sosa EA, Benitez MDJ, De Robertis EM., Dev Biol. June 15, 2017; 426 (2): 176-187.                                  

Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis., Watanabe M, Yasuoka Y, Mawaribuchi S, Kuretani A, Ito M, Kondo M, Ochi H, Ogino H, Fukui A, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 301-324.                          

Eukaryotic initiation factor eIF6 modulates the expression of Kermit 2/XGIPC in IGF- regulated eye development., De Marco N, Tussellino M, Carotenuto R, Ronca R, Rizzolio S, Biffo S, Campanella C., Dev Biol. July 1, 2017; 427 (1): 148-154.        

Upregulation of matrix metalloproteinase triggers transdifferentiation of retinal pigmented epithelial cells in Xenopus laevis: A Link between inflammatory response and regeneration., Naitoh H, Suganuma Y, Ueda Y, Sato T, Hiramuki Y, Fujisawa-Sehara A, Taketani S, Araki M., Dev Neurobiol. September 1, 2017; 77 (9): 1086-1100.                

KDM3A-mediated demethylation of histone H3 lysine 9 facilitates the chromatin binding of Neurog2 during neurogenesis., Lin H, Zhu X, Chen G, Song L, Gao L, Khand AA, Chen Y, Lin G, Tao Q, Tao Q., Development. October 15, 2017; 144 (20): 3674-3685.                          

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 19, 2017; 15 (10): e2004045.                                              

Phosphorylation states change Otx2 activity for cell proliferation and patterning in the Xenopus embryo., Satou Y, Minami K, Hosono E, Okada H, Yasuoka Y, Shibano T, Tanaka T, Taira M., Development. March 12, 2018; 145 (5):                             

Coordinated regulation of the dorsal-ventral and anterior-posterior patterning of Xenopus embryos by the BTB/POZ zinc finger protein Zbtb14., Takebayashi-Suzuki K, Konishi H, Miyamoto T, Nagata T, Uchida M, Suzuki A., Dev Growth Differ. April 1, 2018; 60 (3): 158-173.          

Xenopus ADAM19 regulates Wnt signaling and neural crest specification by stabilizing ADAM13., Li J, Perfetto M, Neuner R, Bahudhanapati H, Christian L, Mathavan K, Bridges LC, Alfandari D, Alfandari D, Wei S., Development. April 4, 2018; 145 (7):                         

The age-regulated zinc finger factor ZNF367 is a new modulator of neuroblast proliferation during embryonic neurogenesis., Naef V, Monticelli S, Corsinovi D, Mazzetto MT, Cellerino A, Ori M., Sci Rep. August 7, 2018; 8 (1): 11836.                      

Nosip functions during vertebrate eye and cranial cartilage development., Flach H, Krieg J, Hoffmeister M, Dietmann P, Reusch A, Wischmann L, Kernl B, Riegger R, Oess S, Kühl SJ., Dev Dyn. September 1, 2018; 247 (9): 1070-1082.                

Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis., Ding Y, Colozza G, Sosa EA, Moriyama Y, Rundle S, Salwinski L, De Robertis EM., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.                    

Identification of retinal homeobox (rax) gene-dependent genes by a microarray approach: The DNA endoglycosylase neil3 is a major downstream component of the rax genetic pathway., Pan Y, Kelly LE, El-Hodiri HM., Dev Dyn. November 1, 2018; 247 (11): 1199-1210.                            

Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development., Kim Y, Jeong Y, Kwon K, Ismail T, Lee HK, Kim C, Park JW, Kwon OS, Kang BS, Lee DS, Park TJ, Kwon T, Lee HS., Epigenetics Chromatin. December 6, 2018; 11 (1): 72.                

Nucleotide receptor P2RY4 is required for head formation via induction and maintenance of head organizer in Xenopus laevis., Harata A, Hirakawa M, Sakuma T, Yamamoto T, Hashimoto C., Dev Growth Differ. February 1, 2019; 61 (2): 186-197.                                

The C-terminus of the retinal homeobox (rax) gene product modulates transcription in a context-dependent manner., Buescher JL, El-Hodiri HM., Mol Vis. February 23, 2019; 25 165-173.      

Jmjd6a regulates GSK3β RNA splicing in Xenopus laevis eye development., Shin JY, Son J, Kim WS, Gwak J, Ju BG., PLoS One. July 30, 2019; 14 (7): e0219800.                      

BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers., Kuznetsov JN, Aguero TH, Owens DA, Kurtenbach S, Field MG, Durante MA, Rodriguez DA, King ML, Harbour JW., Sci Adv. September 18, 2019; 5 (9): eaax1738.        

Bioinformatics Screening of Genes Specific for Well-Regenerating Vertebrates Reveals c-answer, a Regulator of Brain Development and Regeneration., Korotkova DD, Lyubetsky VA, Ivanova AS, Rubanov LI, Seliverstov AV, Zverkov OA, Martynova NY, Nesterenko AM, Tereshina MB, Peshkin L, Zaraisky AG., Cell Rep. October 22, 2019; 29 (4): 1027-1040.e6.                              

miR-199 plays both positive and negative regulatory roles in Xenopus eye development., Ritter RA, Ulrich CH, Brzezinska BN, Shah VV, Zamora MJ, Kelly LE, El-Hodiri HM, Sater AK., Genesis. March 1, 2020; 58 (3-4): e23354.                        

Sprouty2 regulates positioning of retinal progenitors through suppressing the Ras/Raf/MAPK pathway., Sun J, Yoon J, Lee M, Hwang YS, Daar IO., Sci Rep. August 13, 2020; 10 (1): 13752.                      

Hes5.9 Coordinate FGF and Notch Signaling to Modulate Gastrulation via Regulating Cell Fate Specification and Cell Migration in Xenopus tropicalis., Huang X, Zhang L, Yang S, Zhang Y, Wu M, Chen P., Genes (Basel). November 18, 2020; 11 (11):                   

Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos., Umair Z, Kumar S, Rafiq K, Kumar V, Reman ZU, Lee SH, Kim S, Lee JY, Lee U, Kim J., Anim Cells Syst (Seoul). November 27, 2020; 24 (6): 359-370.            

Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway., Colozza G, Jami-Alahmadi Y, Dsouza A, Tejeda-Muñoz N, Albrecht LV, Sosa EA, Wohlschlegel JA, De Robertis EM., Sci Rep. December 9, 2020; 10 (1): 21555.            

Elucidating the framework for specification and determination of the embryonic retina., Louie SH, Fisher M, Grainger RM., Exp Cell Res. December 15, 2020; 397 (2): 112316.

The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus., Zhang F, Zhu X, Wang P, He Q, Huang H, Zheng T, Li Y, Jia H, Xu L, Zhao H, Colozza G, Tao Q, De Robertis EM, Ding Y., Proc Natl Acad Sci U S A. May 18, 2021; 118 (20):           

Retinol binding protein 1 affects Xenopus anterior neural development via all-trans retinoic acid signaling., Flach H, Basten T, Schreiner C, Dietmann P, Greco S, Nies L, Roßmanith N, Walter S, Kühl M, Kühl SJ., Dev Dyn. August 1, 2021; 250 (8): 1096-1112.                

A systemic cell cycle block impacts stage-specific histone modification profiles during Xenopus embryogenesis., Pokrovsky D, Forné I, Straub T, Imhof A, Rupp RAW., PLoS Biol. September 1, 2021; 19 (9): e3001377.                        

The Ribosomal Protein L5 Functions During Xenopus Anterior Development Through Apoptotic Pathways., Schreiner C, Kernl B, Dietmann P, Riegger RJ, Kühl M, Kühl SJ., Front Cell Dev Biol. January 1, 2022; 10 777121.                        

Toxic effects of SiO2NPs in early embryogenesis of Xenopuslaevis., Carotenuto R, Tussellino M, Ronca R, Benvenuto G, Fogliano C, Fusco S, Netti PA., Chemosphere. February 1, 2022; 289 133233.

Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development., Sun J, Yoon J, Lee M, Lee HK, Hwang YS, Daar IO., Cell Rep. February 1, 2022; 38 (5): 110312.                                          

Impact of glyphosate-based herbicide on early embryonic development of the amphibian Xenopus laevis., Flach H, Lenz A, Pfeffer S, Kühl M, Kühl SJ., Aquat Toxicol. March 1, 2022; 244 106081.

Lysosomes are required for early dorsal signaling in the Xenopus embryo., Tejeda-Muñoz N, De Robertis EM., Proc Natl Acad Sci U S A. April 26, 2022; 119 (17): e2201008119.                          

Functions of block of proliferation 1 during anterior development in Xenopus laevis., Gärtner C, Meßmer A, Dietmann P, Kühl M, Kühl SJ., PLoS One. August 2, 2022; 17 (8): e0273507.                        

Regulation of gene expression downstream of a novel Fgf/Erk pathway during Xenopus development., Cowell LM, King M, West H, Broadsmith M, Genever P, Pownall ME, Isaacs HV., PLoS One. January 1, 2023; 18 (10): e0286040.                                  

Production and characterization of monoclonal antibodies to xenopus proteins., Horr B, Kurtz R, Pandey A, Hoffstrom BG, Schock E, LaBonne C, Alfandari D, Alfandari D., Development. February 14, 2023;                 

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