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Summary Expression Phenotypes Gene Literature (164) GO Terms (15) Nucleotides (248) Proteins (86) Interactants (937) Wiki
XB-GENEPAGE-1217555

Papers associated with mapk8



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Activation of mitogen-activated protein kinase cascades by p21-activated protein kinases in cell-free extracts of Xenopus oocytes., Polverino A, Frost J, Yang P, Hutchison M, Neiman AM, Cobb MH, Marcus S., J Biol Chem. November 3, 1995; 270 (44): 26067-70.

Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase., Groom LA, Sneddon AA, Alessi DR, Dowd S, Keyse SM., EMBO J. July 15, 1996; 15 (14): 3621-32.

Selective inhibition of oncogenic ras-p21 in vivo by agents that block its interaction with jun-N-kinase (JNK) and jun proteins. Implications for the design of selective chemotherapeutic agents., Amar S, Glozman A, Chung D, Adler V, Ronai Z, Friedman FK, Robinson R, Brandt-Rauf P, Yamaizumi Z, Pincus MR., Cancer Chemother Pharmacol. January 1, 1997; 41 (1): 79-85.

Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38)., Cuenda A, Cohen P, Buée-Scherrer V, Goedert M., EMBO J. January 15, 1997; 16 (2): 295-305.

Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases., Goedert M, Cuenda A, Craxton M, Jakes R, Cohen P., EMBO J. June 16, 1997; 16 (12): 3563-71.

Activation of the protein kinase p38 in the spindle assembly checkpoint and mitotic arrest., Takenaka K, Moriguchi T, Nishida E., Science. April 24, 1998; 280 (5363): 599-602.

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase., Jacobs D, Glossip D, Xing H, Muslin AJ, Kornfeld K., Genes Dev. January 15, 1999; 13 (2): 163-75.

Distinct domains of mouse dishevelled are responsible for the c-Jun N-terminal kinase/stress-activated protein kinase activation and the axis formation in vertebrates., Moriguchi T, Kawachi K, Kamakura S, Masuyama N, Yamanaka H, Matsumoto K, Kikuchi A, Nishida E., J Biol Chem. October 22, 1999; 274 (43): 30957-62.        

Concentration-dependent positive and negative regulation of a MAP kinase by a MAP kinase kinase., Kieran MW, Katz S, Vail B, Zon LI, Mayer BJ., Oncogene. November 18, 1999; 18 (48): 6647-57.

Cell swelling activates stress-activated protein kinases, p38 MAP kinase and JNK, in renal epithelial A6 cells., Niisato N, Post M, Van Driessche W, Marunaka Y., Biochem Biophys Res Commun. December 20, 1999; 266 (2): 547-50.

Induction of oocyte maturation by jun-N-terminal kinase (JNK) on the oncogenic ras-p21 pathway is dependent on the raf-MEK signal transduction pathway., Chie L, Amar S, Kung HF, Lin MC, Chen H, Chung DL, Adler V, Ronai Z, Friedman FK, Robinson RC, Kovac C, Brandt-Rauf PW, Yamaizumi Z, Michl J, Pincus MR., Cancer Chemother Pharmacol. January 1, 2000; 45 (6): 441-9.

Glutathione-S-Transferase as a selective inhibitor of oncogenic ras-p21-induced mitogenic signaling through blockade of activation of jun by jun-N-terminal kinase., Villafania A, Anwar K, Amar S, Chie L, Way D, Chung DL, Adler V, Ronai Z, Brandt-Rauf PW, Yamaizumii Z, Kung HF, Pincus MR., Ann Clin Lab Sci. January 1, 2000; 30 (1): 57-64.

The cytoskeletal effector xPAK1 is expressed during both ear and lateral line development in Xenopus., Islam N, Poitras L, Moss T., Int J Dev Biol. February 1, 2000; 44 (2): 245-8.          

Making mesoderm--upstream and downstream of Xbra., Smith JC., Int J Dev Biol. January 1, 2001; 45 (1): 219-24.    

c-Jun N-terminal kinase activation in Xenopus laevis eggs and embryos. A possible non-genomic role for the JNK signaling pathway., Bagowski CP, Xiong W, Ferrell JE., J Biol Chem. January 12, 2001; 276 (2): 1459-65.

PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling., Sun TQ, Lu B, Feng JJ, Reinhard C, Jan YN, Fantl WJ, Williams LT., Nat Cell Biol. July 1, 2001; 3 (7): 628-36.

Bistability in the JNK cascade., Bagowski CP, Ferrell JE., Curr Biol. August 7, 2001; 11 (15): 1176-82.

Differences in patterns of activation of MAP kinases induced by oncogenic ras-p21 and insulin in oocytes., Ranginwale M, Smith S, Flom J, Chie L, Kanovsky M, Chung D, Friedman FK, Robinson RC, Brandt-Rauf PW, Yamaizumi Z, Michl J, Pincus MR., Exp Cell Res. September 10, 2001; 269 (1): 162-9.

Role of JNK in hypertonic activation of Cl(-)-dependent Na(+)/H(+) exchange in Xenopus oocytes., Goss GG, Jiang L, Vandorpe DH, Kieller D, Chernova MN, Robertson M, Alper SL., Am J Physiol Cell Physiol. December 1, 2001; 281 (6): C1978-90.

JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates., Yamanaka H, Moriguchi T, Masuyama N, Kusakabe M, Hanafusa H, Takada R, Takada S, Nishida E., EMBO Rep. January 1, 2002; 3 (1): 69-75.

Frizzled receptors activate a novel JNK-dependent pathway that may lead to apoptosis., Lisovsky M, Itoh K, Sokol SY., Curr Biol. January 8, 2002; 12 (1): 53-8.

Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation., Cheyette BN, Waxman JS, Miller JR, Takemaru K, Sheldahl LC, Khlebtsova N, Fox EP, Earnest T, Moon RT., Dev Cell. April 1, 2002; 2 (4): 449-61.  

Molecular cloning and characterization of Strabismus 2 (STB2)., Katoh M., Int J Oncol. May 1, 2002; 20 (5): 993-8.

Non-canonical Wnt signaling in Xenopus: regulation of axis formation and gastrulation., Kühl M., Semin Cell Dev Biol. June 1, 2002; 13 (3): 243-9.        

The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling., Schwarz-Romond T, Asbrand C, Bakkers J, Kühl M, Schaeffer HJ, Huelsken J, Behrens J, Hammerschmidt M, Birchmeier W., Genes Dev. August 15, 2002; 16 (16): 2073-84.

I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways., Kusano S, Raab-Traub N., Mol Cell Biol. September 1, 2002; 22 (18): 6393-405.

A tissue restricted role for the Xenopus Jun N-terminal kinase kinase kinase MLK2 in cement gland and pronephric tubule differentiation., Poitras L, Bisson N, Islam N, Moss T., Dev Biol. February 15, 2003; 254 (2): 200-14.      

The JNK cascade as a biochemical switch in mammalian cells: ultrasensitive and all-or-none responses., Bagowski CP, Besser J, Frey CR, Ferrell JE., Curr Biol. February 18, 2003; 13 (4): 315-20.

The prickle-related gene in vertebrates is essential for gastrulation cell movements., Takeuchi M, Nakabayashi J, Sakaguchi T, Yamamoto TS, Takahashi H, Takeda H, Ueno N., Curr Biol. April 15, 2003; 13 (8): 674-9.        

AKRL1 and AKRL2 activate the JNK pathway., Harada T, Matsuzaki O, Hayashi H, Sugano S, Matsuda A, Nishida E., Genes Cells. May 1, 2003; 8 (5): 493-500.

PAK interacts with NCK and MLK2 to regulate the activation of jun N-terminal kinase., Poitras L, Jean S, Islam N, Moss T., FEBS Lett. May 22, 2003; 543 (1-3): 129-35.

A requirement for MAP kinase in the assembly and maintenance of the mitotic spindle., Horne MM, Guadagno TM., J Cell Biol. June 23, 2003; 161 (6): 1021-8.          

PKC delta is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements., Kinoshita N, Iioka H, Miyakoshi A, Ueno N., Genes Dev. July 1, 2003; 17 (13): 1663-76.                    

The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway., Oishi I, Suzuki H, Onishi N, Takada R, Kani S, Ohkawara B, Koshida I, Suzuki K, Yamada G, Schwabe GC, Mundlos S, Shibuya H, Takada S, Minami Y., Genes Cells. July 1, 2003; 8 (7): 645-54.

A hybrid peptide derived from cecropin-A and magainin-2 inhibits osteoclast differentiation., Kwak HB, Lee SW, Lee DG, Hahm KS, Kim KK, Kim HH, Lee ZH., Life Sci. July 11, 2003; 73 (8): 993-1005.

Roles of PDGF in animal development., Hoch RV, Soriano P., Development. October 1, 2003; 130 (20): 4769-84.            

Intersectin activates Ras but stimulates transcription through an independent pathway involving JNK., Mohney RP, Das M, Bivona TG, Hanes R, Adams AG, Philips MR, O'Bryan JP., J Biol Chem. November 21, 2003; 278 (47): 47038-45.

Xenopus death receptor-M1 and -M2, new members of the tumor necrosis factor receptor superfamily, trigger apoptotic signaling by differential mechanisms., Tamura K, Noyama T, Ishizawa YH, Takamatsu N, Shiba T, Ito M., J Biol Chem. February 27, 2004; 279 (9): 7629-35.              

An effector peptide from glutathione-S-transferase-pi strongly and selectively blocks mitotic signaling by oncogenic ras-p21., Chie L, Adler V, Friedman FK, Chung D, Pincus MR., Protein J. April 1, 2004; 23 (3): 235-8.

Contribution of JNK, Mek, Mos and PI-3K signaling to GVBD in Xenopus oocytes., Mood K, Bong YS, Lee HS, Lee HS, Ishimura A, Daar IO., Cell Signal. May 1, 2004; 16 (5): 631-42.

The neurotrophin-receptor-related protein NRH1 is essential for convergent extension movements., Sasai N, Nakazawa Y, Haraguchi T, Sasai Y., Nat Cell Biol. August 1, 2004; 6 (8): 741-8.

Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK., Unterseher F, Hefele JA, Giehl K, De Robertis EM, Wedlich D, Schambony A., EMBO J. August 18, 2004; 23 (16): 3259-69.

Cross-regulation of Wnt signaling and cell adhesion., Schambony A, Kunz M, Gradl D., Differentiation. September 1, 2004; 72 (7): 307-18.

Sef interacts with TAK1 and mediates JNK activation and apoptosis., Yang X, Kovalenko D, Nadeau RJ, Harkins LK, Mitchell J, Zubanova O, Chen PY, Friesel R., J Biol Chem. September 10, 2004; 279 (37): 38099-102.

Role of TGF-beta1 and JNK signaling in capillary tube patterning., Bein K, Odell-Fiddler ET, Drinane M., Am J Physiol Cell Physiol. October 1, 2004; 287 (4): C1012-22.

FGF receptor phosphotyrosine 766 is a target for Grb14 to inhibit MDA-MB-231 human breast cancer cell signaling., Cailliau K, Perdereau D, Lescuyer A, Chen H, Garbay C, Vilain JP, Burnol AF, Browaeys-Poly E., Anticancer Res. January 1, 2005; 25 (6B): 3877-82.

Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling., Itoh K, Brott BK, Bae GU, Ratcliffe MJ, Sokol SY., J Biol. January 1, 2005; 4 (1): 3.                  

Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex., Foley AC, Mercola M., Genes Dev. February 1, 2005; 19 (3): 387-96.            

Wnt11-R, a protein closely related to mammalian Wnt11, is required for heart morphogenesis in Xenopus., Garriock RJ, D'Agostino SL, Pilcher KC, Krieg PA., Dev Biol. March 1, 2005; 279 (1): 179-92.          

ERK2 is required for FGF1-induced JNK1 phosphorylation in Xenopus oocyte expressing FGF receptor 1., Browaeys-Poly E, Fafeur V, Vilain JP, Cailliau K., Biochim Biophys Acta. March 22, 2005; 1743 (1-2): 1-4.

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