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Summary Expression Phenotypes Gene Literature (66) GO Terms (8) Nucleotides (163) Proteins (51) Interactants (708) Wiki
XB--487419

Papers associated with smo



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9 paper(s) referencing morpholinos

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Cell lineage-guided mass spectrometry reveals increased energy metabolism and reactive oxygen species in the vertebrate organizer., Baxi AB, Li J, Quach VM, Pade LR, Moody SA, Nemes P., Proc Natl Acad Sci U S A. February 6, 2024; 121 (6): e2311625121.                  


Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs., Bredeson JV, Mudd AB, Medina-Ruiz S, Mitros T, Smith OK, Miller KE, Lyons JB, Batra SS, Park J, Berkoff KC, Plott C, Grimwood J, Schmutz J, Aguirre-Figueroa G, Khokha MK, Lane M, Philipp I, Laslo M, Hanken J, Kerdivel G, Buisine N, Sachs LM, Buchholz DR, Kwon T, Smith-Parker H, Gridi-Papp M, Ryan MJ, Denton RD, Malone JH, Wallingford JB, Straight AF, Heald R, Hockemeyer D, Harland RM, Rokhsar DS., Nat Commun. January 17, 2024; 15 (1): 579.                                            


Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease., Mishra-Gorur K, Barak T, Kaulen LD, Henegariu O, Jin SC, Aguilera SM, Yalbir E, Goles G, Nishimura S, Miyagishima D, Djenoune L, Altinok S, Rai DK, Viviano S, Prendergast A, Zerillo C, Ozcan K, Baran B, Sencar L, Goc N, Yarman Y, Ercan-Sencicek AG, Bilguvar K, Lifton RP, Moliterno J, Louvi A, Yuan S, Deniz E, Brueckner M, Gunel M., Proc Natl Acad Sci U S A. April 18, 2023; 120 (16): e2214997120.                                            


Dodecaploid Xenopus longipes provides insight into the emergence of size scaling relationships during development., Miller KE, Cadart C, Heald R., Curr Biol. April 10, 2023; 33 (7): 1327-1336.e4.                


Cilia-localized GID/CTLH ubiquitin ligase complex regulates protein homeostasis of sonic hedgehog signaling components., Hantel F, Liu H, Fechtner L, Neuhaus H, Ding J, Arlt D, Walentek P, Villavicencio-Lorini P, Gerhardt C, Hollemann T, Pfirrmann T., J Cell Sci. May 1, 2022; 135 (9):                                     


Lysosomal degradation of the maternal dorsal determinant Hwa safeguards dorsal body axis formation., Zhu X, Wang P, Wei J, Li Y, Zhai J, Zheng T, Tao Q, Tao Q., EMBO Rep. December 6, 2021; 22 (12): e53185.


Identification of the centrosomal maturation factor SSX2IP as a Wtip-binding partner by targeted proximity biotinylation., Reis AH, Xiang B, Ossipova O, Itoh K, Sokol SY., PLoS One. October 28, 2021; 16 (10): e0259068.              


Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration in Xenopus laevis larvae., Hamilton AM, Balashova OA, Borodinsky LN., Elife. May 6, 2021; 10                               


A temporally resolved transcriptome for developing "Keller" explants of the Xenopus laevis dorsal marginal zone., Kakebeen AD, Huebner RJ, Shindo A, Kwon K, Kwon T, Wills AE, Wallingford JB., Dev Dyn. May 1, 2021; 250 (5): 717-731.              


TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis., Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X., Elife. September 14, 2020; 9                                                                                           


Smoothened stimulation by membrane sterols drives Hedgehog pathway activity., Deshpande I, Liang J, Hedeen D, Roberts KJ, Zhang Y, Ha B, Latorraca NR, Faust B, Dror RO, Beachy PA, Myers BR, Manglik A., Nature. July 1, 2019; 571 (7764): 284-288.


Non-centrosomal microtubule structures regulated by egg activation signaling contribute to cytoplasmic and cortical reorganization in the ascidian egg., Goto T, Kanda K, Nishikata T., Dev Biol. April 15, 2019; 448 (2): 161-172.                  


Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development., Steimle JD, Rankin SA, Rankin SA, Slagle CE, Bekeny J, Rydeen AB, Chan SS, Kweon J, Yang XH, Ikegami K, Nadadur RD, Rowton M, Hoffmann AD, Lazarevic S, Thomas W, Boyle Anderson EAT, Horb ME, Luna-Zurita L, Ho RK, Kyba M, Jensen B, Zorn AM, Conlon FL, Moskowitz IP., Proc Natl Acad Sci U S A. November 6, 2018; 115 (45): E10615-E10624.                                  


Notch1 is asymmetrically distributed from the beginning of embryogenesis and controls the ventral center., Castro Colabianchi AM, Revinski DR, Encinas PI, Baez MV, Monti RJ, Rodríguez Abinal M, Kodjabachian L, Franchini LF, López SL., Development. July 17, 2018; 145 (14):                           


Structural Basis of Smoothened Activation in Hedgehog Signaling., Huang P, Zheng S, Wierbowski BM, Kim Y, Nedelcu D, Aravena L, Liu J, Kruse AC, Salic A., Cell. July 12, 2018; 174 (2): 312-324.e16.


Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney., Zhang B, Tran U, Wessely O., Development. March 22, 2018; 145 (6):                         


Hyperinnervation improves Xenopus laevis limb regeneration., Mitogawa K, Makanae A, Satoh A., Dev Biol. January 15, 2018; 433 (2): 276-286.                    


Sonic hedgehog antagonists reduce size and alter patterning of the frog inner ear., Zarei S, Zarei K, Fritzsch B, Elliott KL., Dev Neurobiol. December 1, 2017; 77 (12): 1385-1400.                


KDM3A-mediated demethylation of histone H3 lysine 9 facilitates the chromatin binding of Neurog2 during neurogenesis., Lin H, Zhu X, Chen G, Song L, Gao L, Khand AA, Chen Y, Lin G, Tao Q, Tao Q., Development. October 15, 2017; 144 (20): 3674-3685.                          


High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Michiue T, Yamamoto T, Yasuoka Y, Goto T, Ikeda T, Nagura K, Nakayama T, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 270-290.                  


Genome evolution in the allotetraploid frog Xenopus laevis., Session AM, Uno Y, Kwon T, Chapman JA, Toyoda A, Takahashi S, Fukui A, Hikosaka A, Suzuki A, Kondo M, van Heeringen SJ, Quigley I, Heinz S, Ogino H, Ochi H, Hellsten U, Lyons JB, Simakov O, Putnam N, Stites J, Kuroki Y, Tanaka T, Michiue T, Watanabe M, Bogdanovic O, Lister R, Georgiou G, Paranjpe SS, van Kruijsbergen I, Shu S, Carlson J, Kinoshita T, Ohta Y, Mawaribuchi S, Jenkins J, Grimwood J, Schmutz J, Mitros T, Mozaffari SV, Suzuki Y, Haramoto Y, Yamamoto TS, Takagi C, Heald R, Miller K, Haudenschild C, Kitzman J, Nakayama T, Izutsu Y, Robert J, Fortriede J, Burns K, Lotay V, Karimi K, Yasuoka Y, Dichmann DS, Flajnik MF, Houston DW, Shendure J, DuPasquier L, Vize PD, Zorn AM, Ito M, Marcotte EM, Wallingford JB, Ito Y, Asashima M, Ueno N, Matsuda Y, Veenstra GJ, Fujiyama A, Harland RM, Taira M, Rokhsar DS., Nature. October 20, 2016; 538 (7625): 336-343.                              


Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling., Huang P, Nedelcu D, Watanabe M, Jao C, Kim Y, Liu J, Salic A., Cell. August 25, 2016; 166 (5): 1176-1187.e14.


A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification., Rankin SA, Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM., Cell Rep. June 28, 2016; 16 (1): 66-78.                                              


Cell-fate determination by ubiquitin-dependent regulation of translation., Werner A, Iwasaki S, McGourty CA, Medina-Ruiz S, Teerikorpi N, Fedrigo I, Ingolia NT, Rape M., Nature. September 24, 2015; 525 (7570): 523-7.                            


Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan., Chang TH, Hsieh FL, Zebisch M, Harlos K, Elegheert J, Jones EY., Elife. July 9, 2015; 4                               


Spatiotemporal integration of developmental cues in neural development., Borodinsky LN, Belgacem YH, Swapna I, Visina O, Balashova OA, Sequerra EB, Tu MK, Levin JB, Spencer KA, Castro PA, Hamilton AM, Shim S., Dev Neurobiol. April 1, 2015; 75 (4): 349-59.    


Early development of the neural plate: new roles for apoptosis and for one of its main effectors caspase-3., Juraver-Geslin HA, Durand BC., Genesis. February 1, 2015; 53 (2): 203-24.          


Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression., Shi J, Zhao Y, Galati D, Winey M, Klymkowsky MW., Dev Biol. November 15, 2014; 395 (2): 287-98.                    


Neural transcription factors: from embryos to neural stem cells., Lee HK, Lee HS, Moody SA., Mol Cells. October 31, 2014; 37 (10): 705-12.    


Sulf1 influences the Shh morphogen gradient during the dorsal ventral patterning of the neural tube in Xenopus tropicalis., Ramsbottom SA, Maguire RJ, Fellgett SW, Pownall ME., Dev Biol. July 15, 2014; 391 (2): 207-18.                  


MicroRNAs are critical regulators of tuberous sclerosis complex and mTORC1 activity in the size control of the Xenopus kidney., Romaker D, Kumar V, Cerqueira DM, Cox RM, Wessely O., Proc Natl Acad Sci U S A. April 29, 2014; 111 (17): 6335-40.                                                          


Reagents for developmental regulation of Hedgehog signaling., Lewis C, Krieg PA., Methods. April 1, 2014; 66 (3): 390-7.


Stabilization of speckle-type POZ protein (Spop) by Daz interacting protein 1 (Dzip1) is essential for Gli turnover and the proper output of Hedgehog signaling., Schwend T, Jin Z, Jiang K, Mitchell BJ, Jia J, Yang J., J Biol Chem. November 8, 2013; 288 (45): 32809-32820.                


Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling., Nedelcu D, Liu J, Xu Y, Xu Y, Jao C, Salic A., Nat Chem Biol. September 1, 2013; 9 (9): 557-64.          


Regulation of G-protein signaling via Gnas is required to regulate proximal tubular growth in the Xenopus pronephros., Zhang B, Romaker D, Ferrell N, Wessely O., Dev Biol. April 1, 2013; 376 (1): 31-42.                        


Indian hedgehog signaling is required for proper formation, maintenance and migration of Xenopus neural crest., Agüero TH, Fernández JP, López GA, Tríbulo C, Aybar MJ., Dev Biol. April 15, 2012; 364 (2): 99-113.                    


Thyroid hormone-induced sonic hedgehog signal up-regulates its own pathway in a paracrine manner in the Xenopus laevis intestine during metamorphosis., Hasebe T, Kajita M, Fu L, Shi YB, Ishizuya-Oka A., Dev Dyn. February 1, 2012; 241 (2): 403-14.        


MIM regulates vertebrate neural tube closure., Liu W, Komiya Y, Mezzacappa C, Khadka DK, Runnels L, Habas R., Development. May 1, 2011; 138 (10): 2035-47.                            


Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord., Belgacem YH, Borodinsky LN., Proc Natl Acad Sci U S A. March 15, 2011; 108 (11): 4482-7.        


Knockdown of SPARC leads to decreased cell-cell adhesion and lens cataracts during post-gastrula development in Xenopus laevis., Huynh MH, Zhu SJ, Kollara A, Brown T, Winklbauer R, Ringuette M., Dev Genes Evol. March 1, 2011; 220 (11-12): 315-27.


A conserved function of the chromatin ATPase Kismet in the regulation of hedgehog expression., Terriente-Félix A, Molnar C, Gómez-Skarmeta JL, de Celis JF., Dev Biol. February 15, 2011; 350 (2): 382-92.                  


[Passive and active reactions of embryonic tissues to the action of dosed mechanical forces]., Mansurov AN, Belousov LV., Ontogenez. January 1, 2011; 42 (2): 126-32.


Xenopus sonic hedgehog guides retinal axons along the optic tract., Gordon L, Mansh M, Kinsman H, Morris AR., Dev Dyn. November 1, 2010; 239 (11): 2921-32.      


Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain., Zhao L, Saitsu H, Sun X, Shiota K, Ishibashi M., Mech Dev. January 1, 2010; 127 (1-2): 62-72.                


Effects of activation of hedgehog signaling on patterning, growth, and differentiation in Xenopus froglet limb regeneration., Yakushiji N, Suzuki M, Satoh A, Ide H, Tamura K, Tamura K., Dev Dyn. August 1, 2009; 238 (8): 1887-96.          


Enabled (Xena) regulates neural plate morphogenesis, apical constriction, and cellular adhesion required for neural tube closure in Xenopus., Roffers-Agarwal J, Xanthos JB, Kragtorp KA, Miller JR., Dev Biol. February 15, 2008; 314 (2): 393-403.            


Retinoic acid-inducible G protein-coupled receptors bind to frizzled receptors and may activate non-canonical Wnt signaling., Harada Y, Yokota C, Habas R, Slusarski DC, He X., Biochem Biophys Res Commun. July 13, 2007; 358 (4): 968-75.        


Two oppositely localised frizzled RNAs as axis determinants in a cnidarian embryo., Momose T, Houliston E., PLoS Biol. April 1, 2007; 5 (4): e70.                


PP2A:B56epsilon is required for eye induction and eye field separation., Rorick AM, Mei W, Liette NL, Phiel C, El-Hodiri HM, Yang J., Dev Biol. February 15, 2007; 302 (2): 477-93.                  


Suppressing Wnt signaling by the hedgehog pathway through sFRP-1., He J, Sheng T, Stelter AA, Li C, Zhang X, Sinha M, Luxon BA, Xie J., J Biol Chem. November 24, 2006; 281 (47): 35598-602.

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