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Summary Expression Phenotypes Gene Literature (40) GO Terms (15) Nucleotides (180) Proteins (50) Interactants (184) Wiki
XB-GENEPAGE-973432

Papers associated with gnaq



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G alpha 11 and G alpha q guanine nucleotide regulatory proteins differentially modulate the response to thyrotropin-releasing hormone in Xenopus oocytes., Lipinsky D, Gershengorn MC, Oron Y., FEBS Lett. July 28, 1992; 307 (2): 237-40.

Neuromedin B receptor, expressed in Xenopus laevis oocytes, selectively couples to G alpha q and not G alpha 11., Shapira H, Way J, Lipinsky D, Oron Y, Battey JF., FEBS Lett. July 4, 1994; 348 (1): 89-92.

The G protein beta gamma subunit transduces the muscarinic receptor signal for Ca2+ release in Xenopus oocytes., Stehno-Bittel L, Krapivinsky G, Krapivinsky L, Perez-Terzic C, Clapham DE., J Biol Chem. December 15, 1995; 270 (50): 30068-74.

Increased expression of alphaq family G-proteins during oocyte maturation and early development of Xenopus laevis., Gallo CJ, Jones TL, Aragay AM, Jaffe LA., Dev Biol. July 10, 1996; 177 (1): 300-8.

Identification of melanin concentrating hormone (MCH) as the natural ligand for the orphan somatostatin-like receptor 1 (SLC-1)., Bächner D, Kreienkamp H, Weise C, Buck F, Richter D., FEBS Lett. September 3, 1999; 457 (3): 522-4.

Calcium release at fertilization of Xenopus eggs requires type I IP(3) receptors, but not SH2 domain-mediated activation of PLCgamma or G(q)-mediated activation of PLCbeta., Runft LL, Watras J, Jaffe LA., Dev Biol. October 15, 1999; 214 (2): 399-411.

RGS proteins inhibit Xwnt-8 signaling in Xenopus embryonic development., Wu C, Zeng Q, Blumer KJ, Muslin AJ., Development. July 1, 2000; 127 (13): 2773-84.   


Regulation of GIRK channel deactivation by Galpha(q) and Galpha(i/o) pathways., Mark MD, Ruppersberg JP, Herlitze S., Neuropharmacology. September 1, 2000; 39 (12): 2360-73.

Galphas family G proteins activate IP(3)-Ca(2+) signaling via gbetagamma and transduce ventralizing signals in Xenopus., Kume S, Inoue T, Mikoshiba K., Dev Biol. October 1, 2000; 226 (1): 88-103.   


Inhibition of a Gi-activated potassium channel (GIRK1/4) by the Gq-coupled m1 muscarinic acetylcholine receptor., Hill JJ, Peralta EG., J Biol Chem. February 23, 2001; 276 (8): 5505-10.

Genomic and functional characteristics of novel human pancreatic 2P domain K(+) channels., Girard C, Duprat F, Terrenoire C, Tinel N, Fosset M, Romey G, Lazdunski M, Lesage F., Biochem Biophys Res Commun. March 23, 2001; 282 (1): 249-56.

Galpha(14) links a variety of G(i)- and G(s)-coupled receptors to the stimulation of phospholipase C., Ho MK, Yung LY, Chan JS, Chan JH, Wong CS, Wong YH., Br J Pharmacol. April 1, 2001; 132 (7): 1431-40.

Inhibition of m3 muscarinic acetylcholine receptors by local anaesthetics., Hollmann MW, Ritter CH, Henle P, de Klaver M, Kamatchi GL, Durieux ME., Br J Pharmacol. May 1, 2001; 133 (1): 207-16.

Inhibition of TASK-1 potassium channel by phospholipase C., Czirják G, Petheo GL, Spät A, Enyedi P., Am J Physiol Cell Physiol. August 1, 2001; 281 (2): C700-8.

Identification of a nonmammalian Golf subtype: functional role in olfactory signaling of airborne odorants in Xenopus laevis., Mezler M, Fleischer J, Conzelmann S, Korchi A, Widmayer P, Breer H, Boekhoff I., J Comp Neurol. October 29, 2001; 439 (4): 400-10.   


Activation of inositol 1,4,5-trisphosphate receptor is essential for the opening of mouse TRP5 channels., Kanki H, Kinoshita M, Akaike A, Satoh M, Mori Y, Kaneko S., Mol Pharmacol. November 1, 2001; 60 (5): 989-98.

Possible coupling of prostaglandin E receptor EP(1) to TRP5 expressed in Xenopus laevis oocytes., Tabata H, Tanaka S, Sugimoto Y, Kanki H, Kaneko S, Ichikawa A., Biochem Biophys Res Commun. November 1, 2002; 298 (3): 398-402.

A receptor linked to a Gi-family G-protein functions in initiating oocyte maturation in starfish but not frogs., Kalinowski RR, Jaffe LA, Foltz KR, Giusti AF., Dev Biol. January 1, 2003; 253 (1): 139-49.

P2Y receptors modulate ion channel function through interactions involving the C-terminal domain., Lee SY, Wolff SC, Nicholas RA, O'Grady SM., Mol Pharmacol. April 1, 2003; 63 (4): 878-85.

Salvinorin A, an active component of the hallucinogenic sage salvia divinorum is a highly efficacious kappa-opioid receptor agonist: structural and functional considerations., Chavkin C, Sud S, Jin W, Stewart J, Zjawiony JK, Siebert DJ, Toth BA, Hufeisen SJ, Roth BL., J Pharmacol Exp Ther. March 1, 2004; 308 (3): 1197-203.

Modulation of cardiac Ca2+ channel by Gq-activating neurotransmitters reconstituted in Xenopus oocytes., Weiss S, Doan T, Bernstein KE, Dascal N., J Biol Chem. March 26, 2004; 279 (13): 12503-10.

Characteristic interactions with phosphatidylinositol 4,5-bisphosphate determine regulation of kir channels by diverse modulators., Du X, Zhang H, Lopes C, Mirshahi T, Rohacs T, Logothetis DE., J Biol Chem. September 3, 2004; 279 (36): 37271-81.

An inwardly rectifying whole cell current induced by Gq-coupled receptors., Buchholz B, Tauber R, Steffl D, Walz G, Köttgen M., Biochem Biophys Res Commun. September 10, 2004; 322 (1): 177-85.

Analysis of the effects of halothane on Gi-coupled muscarinic M2 receptor signaling in Xenopus oocytes using a chimeric G alpha protein., Minami K, Uezono Y, Shiraishi M, Okamoto T, Ogata J, Horishita T, Taniyama K, Shigematsu A., Pharmacology. November 1, 2004; 72 (3): 205-12.

Use of Caenorhabditis elegans G{alpha}q chimeras to detect G-protein-coupled receptor signals., Walker MW, Jones KA, Tamm J, Zhong H, Smith KE, Gerald C, Vaysse P, Branchek TA., J Biomol Screen. March 1, 2005; 10 (2): 127-36.

Identification of novel genes affecting mesoderm formation and morphogenesis through an enhanced large scale functional screen in Xenopus., Chen JA, Voigt J, Gilchrist M, Papalopulu N, Amaya E., Mech Dev. March 1, 2005; 122 (3): 307-31.   


Protein kinase C shifts the voltage dependence of KCNQ/M channels expressed in Xenopus oocytes., Nakajo K, Kubo Y., J Physiol. November 15, 2005; 569 (Pt 1): 59-74.

RGS3 and RGS4 differentially associate with G protein-coupled receptor-Kir3 channel signaling complexes revealing two modes of RGS modulation. Precoupling and collision coupling., Jaén C, Doupnik CA., J Biol Chem. November 10, 2006; 281 (45): 34549-60.

Pharmacological characterization of mouse GPRC6A, an L-alpha-amino-acid receptor modulated by divalent cations., Christiansen B, Hansen KB, Wellendorph P, Bräuner-Osborne H., Br J Pharmacol. March 1, 2007; 150 (6): 798-807.

Intracellular signal transduction by the extracellular calcium-sensing receptor of Xenopus melanotrope cells., van den Hurk MJ, Cruijsen PM, Schoeber JP, Scheenen WJ, Roubos EW, Jenks BG., Gen Comp Endocrinol. June 1, 2008; 157 (2): 156-64.

Modulation of group III metabotropic glutamate receptors by hydrogen ions., Levinthal C, Barkdull L, Jacobson P, Storjohann L, Van Wagenen BC, Stormann TM, Hammerland LG., Pharmacology. January 1, 2009; 83 (2): 88-94.

Xenopus oocyte electrophysiology in GPCR drug discovery., Hansen KB, Bräuner-Osborne H., Methods Mol Biol. January 1, 2009; 552 343-57.

Pain-associated signals, acidosis and lysophosphatidic acid, modulate the neuronal K(2P)2.1 channel., Cohen A, Sagron R, Somech E, Segal-Hayoun Y, Zilberberg N., Mol Cell Neurosci. March 1, 2009; 40 (3): 382-9.

An in vivo biosensor for neurotransmitter release and in situ receptor activity., Nguyen QT, Schroeder LF, Mank M, Muller A, Taylor P, Griesbeck O, Kleinfeld D., Nat Neurosci. January 1, 2010; 13 (1): 127-132.   


Analysis of the effects of anesthetics and ethanol on mu-opioid receptor., Minami K, Sudo Y, Shiraishi S, Seo M, Uezono Y., J Pharmacol Sci. January 1, 2010; 112 (4): 424-31.

Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs., Fribourg M, Moreno JL, Holloway T, Provasi D, Baki L, Mahajan R, Park G, Adney SK, Hatcher C, Eltit JM, Ruta JD, Albizu L, Li Z, Umali A, Shim J, Fabiato A, MacKerell AD, Brezina V, Sealfon SC, Filizola M, González-Maeso J, Logothetis DE., Cell. November 23, 2011; 147 (5): 1011-23.

PIP2 hydrolysis stimulates the electrogenic Na+-bicarbonate cotransporter NBCe1-B and -C variants expressed in Xenopus laevis oocytes., Thornell IM, Wu J, Liu X, Bevensee MO., J Physiol. December 1, 2012; 590 (23): 5993-6011.

Mas-related G protein-coupled receptor D is coupled to endogenous calcium-activated chloride channel in Xenopus oocytes., Zhuo RG, Ma XY, Zhou PL, Liu XY, Zhang K, Wei XL, Yan HT, Xu JP, Zheng JQ., J Physiol Biochem. March 1, 2014; 70 (1): 185-91.

Expression profiles of the Gα subunits during Xenopus tropicalis embryonic development., Fuentealba J, Toro-Tapia G, Rodriguez M, Arriagada C, Maureira A, Beyer A, Villaseca S, Leal JI, Hinrichs MV, Olate J, Caprile T, Torrejón M., Gene Expr Patterns. September 1, 2016; 22 (1): 15-25.   


Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney., Zhang B, Tran U, Wessely O., Development. March 22, 2018; 145 (6):   

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