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Summary Expression Phenotypes Gene Literature (229) GO Terms (4) Nucleotides (67) Proteins (40) Interactants (939) Wiki
XB-GENEPAGE-853107

Papers associated with en2



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Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction., Wang Y, Fu Y, Gao L, Zhu G, Liang J, Gao C, Huang B, Fenger U, Niehrs C, Chen YG, Chen YG, Wu W., J Biol Chem. April 2, 2010; 285 (14): 10890-901.                            


The Pax3 and Pax7 paralogs cooperate in neural and neural crest patterning using distinct molecular mechanisms, in Xenopus laevis embryos., Maczkowiak F, Matéos S, Wang E, Roche D, Harland R, Monsoro-Burq AH., Dev Biol. April 15, 2010; 340 (2): 381-96.                                                    


En2, Pax2/5 and Tcf-4 transcription factors cooperate in patterning the Xenopus brain., Koenig SF, Brentle S, Hamdi K, Fichtner D, Wedlich D, Gradl D., Dev Biol. April 15, 2010; 340 (2): 318-28.                  


FMR1/FXR1 and the miRNA pathway are required for eye and neural crest development., Gessert S, Bugner V, Tecza A, Pinker M, Kühl M., Dev Biol. May 1, 2010; 341 (1): 222-35.                                                              


Neural crest migration requires the activity of the extracellular sulphatases XtSulf1 and XtSulf2., Guiral EC, Faas L, Pownall ME., Dev Biol. May 15, 2010; 341 (2): 375-88.                              


Polypyrimidine tract-binding protein is required for the repression of gene expression by all-trans retinoic acid., Tamanoue Y, Yamagishi M, Hongo I, Okamoto H., Dev Growth Differ. June 1, 2010; 52 (5): 469-79.                    


Anterior neural development requires Del1, a matrix-associated protein that attenuates canonical Wnt signaling via the Ror2 pathway., Takai A, Inomata H, Arakawa A, Yakura R, Matsuo-Takasaki M, Sasai Y., Development. October 1, 2010; 137 (19): 3293-302.            


[Two peroxiredoxins 6 of Xenopus laevis]., Sharapov MG, Novoselov VI, Fesenko EE, Ravin VK., Mol Biol (Mosk). January 1, 2011; 45 (6): 1017-25.


EBF factors drive expression of multiple classes of target genes governing neuronal development., Green YS, Vetter ML., Neural Dev. April 30, 2011; 6 19.                                                          


Peter Pan functions independently of its role in ribosome biogenesis during early eye and craniofacial cartilage development in Xenopus laevis., Bugner V, Tecza A, Gessert S, Kühl M., Development. June 1, 2011; 138 (11): 2369-78.                        


Notch destabilises maternal beta-catenin and restricts dorsal-anterior development in Xenopus., Acosta H, López SL, Revinski DR, Carrasco AE., Development. June 1, 2011; 138 (12): 2567-79.                          


Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation., Liang J, Fu Y, Cruciat CM, Jia S, Wang Y, Tong Z, Tao Q, Tao Q, Ingelfinger D, Boutros M, Meng A, Niehrs C, Wu W., Mol Cell Biol. July 1, 2011; 31 (13): 2577-90.


Focal adhesion kinase protein regulates Wnt3a gene expression to control cell fate specification in the developing neural plate., Fonar Y, Gutkovich YE, Root H, Malyarova A, Aamar E, Golubovskaya VM, Elias S, Elkouby YM, Frank D., Mol Biol Cell. July 1, 2011; 22 (13): 2409-21.                  


Xenopus laevis insulin receptor substrate IRS-1 is important for eye development., Bugner V, Aurhammer T, Kühl M., Dev Dyn. July 1, 2011; 240 (7): 1705-15.            


Eukaryotic initiation factor 6 (eif6) overexpression affects eye development in Xenopus laevis., De Marco N, Tussellino M, Vitale A, Campanella C., Differentiation. September 1, 2011; 82 (2): 108-15.          


A novel mechanism for the transcriptional regulation of Wnt signaling in development., Vacik T, Stubbs JL, Lemke G., Genes Dev. September 1, 2011; 25 (17): 1783-95.      


The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo., Min TH, Kriebel M, Hou S, Pera EM., Dev Biol. October 1, 2011; 358 (1): 262-76.                            


The forkhead transcription factor FoxB1 regulates the dorsal-ventral and anterior-posterior patterning of the ectoderm during early Xenopus embryogenesis., Takebayashi-Suzuki K, Kitayama A, Terasaka-Iioka C, Ueno N, Suzuki A., Dev Biol. December 1, 2011; 360 (1): 11-29.              


xCOUP-TF-B regulates xCyp26 transcription and modulates retinoic acid signaling for anterior neural patterning in Xenopus., Tanibe M, Ishiura S, Asashima M, Michiue T., Int J Dev Biol. January 1, 2012; 56 (4): 239-44.            


Short chain dehydrogenase/reductase rdhe2 is a novel retinol dehydrogenase essential for frog embryonic development., Belyaeva OV, Lee SA, Adams MK, Chang C, Kedishvili NY., J Biol Chem. March 16, 2012; 287 (12): 9061-71.              


A hindbrain-repressive Wnt3a/Meis3/Tsh1 circuit promotes neuronal differentiation and coordinates tissue maturation., Elkouby YM, Polevoy H, Gutkovich YE, Michaelov A, Frank D., Development. April 1, 2012; 139 (8): 1487-97.                    


Plasma membrane cholesterol depletion disrupts prechordal plate and affects early forebrain patterning., Reis AH, Almeida-Coburn KL, Louza MP, Cerqueira DM, Aguiar DP, Silva-Cardoso L, Mendes FA, Andrade LR, Einicker-Lamas M, Atella GC, Brito JM, Abreu JG., Dev Biol. May 15, 2012; 365 (2): 350-62.                    


ATP4a is required for Wnt-dependent Foxj1 expression and leftward flow in Xenopus left-right development., Walentek P, Beyer T, Thumberger T, Schweickert A, Blum M., Cell Rep. May 31, 2012; 1 (5): 516-27.                              


Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation., Zhang X, Abreu JG, Yokota C, MacDonald BT, Singh S, Coburn KL, Cheong SM, Zhang MM, Ye QZ, Hang HC, Steen H, He X., Cell. June 22, 2012; 149 (7): 1565-77.                      


Subfunctionalization and neofunctionalization of vertebrate Lef/Tcf transcription factors., Klingel S, Morath I, Strietz J, Menzel K, Holstein TW, Gradl D., Dev Biol. August 1, 2012; 368 (1): 44-53.              


Involvement of XZFP36L1, an RNA-binding protein, in Xenopus neural development., Xia YJ, Zhao SH, Mao BY., Dongwuxue Yanjiu. December 1, 2012; 33 (E5-6): E82-8.                


An intact brachyury function is necessary to prevent spurious axial development in Xenopus laevis., Aguirre CE, Murgan S, Carrasco AE, López SL., PLoS One. January 1, 2013; 8 (1): e54777.                                      


Xnr3 affects brain patterning via cell migration in the neural-epidermal tissue boundary during early Xenopus embryogenesis., Morita M, Yamashita S, Matsukawa S, Haramoto Y, Takahashi S, Asashima M, Michiue T., Int J Dev Biol. January 1, 2013; 57 (9-10): 779-86.          


Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling., Huang X, McGann JC, Liu BY, Hannoush RN, Lill JR, Pham V, Newton K, Kakunda M, Liu J, Yu C, Hymowitz SG, Hongo JA, Wynshaw-Boris A, Polakis P, Harland RM, Dixit VM., Science. March 22, 2013; 339 (6126): 1441-5.


β-Adrenergic signaling promotes posteriorization in Xenopus early development., Mori S, Moriyama Y, Yoshikawa K, Furukawa T, Kuroda H., Dev Growth Differ. April 1, 2013; 55 (3): 350-8.            


BMP signal attenuates FGF pathway in anteroposterior neural patterning., Cho GS, Choi SC, Han JK., Biochem Biophys Res Commun. May 10, 2013; 434 (3): 509-15.        


The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling., Wang F, Hu W, Xian J, Ohnuma S, Brenton JD., Dev Biol. July 1, 2013; 379 (1): 16-27.                            


Xenopus Nkx6.1 and Nkx6.2 are required for mid-hindbrain boundary development., Ma P, Xia Y, Ma L, Zhao S, Mao B., Dev Genes Evol. July 1, 2013; 223 (4): 253-9.


sox4 and sox11 function during Xenopus laevis eye development., Cizelsky W, Hempel A, Metzig M, Tao S, Hollemann T, Kühl M, Kühl SJ., PLoS One. July 1, 2013; 8 (7): e69372.              


Dhrs3 protein attenuates retinoic acid signaling and is required for early embryonic patterning., Kam RK, Shi W, Chan SO, Chen Y, Xu G, Lau CB, Fung KP, Chan WY, Zhao H., J Biol Chem. November 1, 2013; 288 (44): 31477-87.                    


Loss of Xenopus cadherin-11 leads to increased Wnt/β-catenin signaling and up-regulation of target genes c-myc and cyclin D1 in neural crest., Koehler A, Schlupf J, Schneider M, Kraft B, Winter C, Kashef J., Dev Biol. November 1, 2013; 383 (1): 132-45.                        


Role of Sp5 as an essential early regulator of neural crest specification in xenopus., Park DS, Seo JH, Hong M, Bang W, Han JK, Choi SC., Dev Dyn. December 1, 2013; 242 (12): 1382-94.                


FoxA4 favours notochord formation by inhibiting contiguous mesodermal fates and restricts anterior neural development in Xenopus embryos., Murgan S, Castro Colabianchi AM, Monti RJ, Boyadjián López LE, Aguirre CE, Stivala EG, Carrasco AE, López SL., PLoS One. January 1, 2014; 9 (10): e110559.                              


An essential role for LPA signalling in telencephalon development., Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L., Development. February 1, 2014; 141 (4): 940-9.                            


The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube., Hanotel J, Bessodes N, Thélie A, Hedderich M, Parain K, Van Driessche B, Brandão Kde O, Kricha S, Jorgensen MC, Grapin-Botton A, Serup P, Van Lint C, Perron M, Pieler T, Henningfeld KA, Bellefroid EJ., Dev Biol. February 15, 2014; 386 (2): 340-57.                                                                    


Spalt-like 4 promotes posterior neural fates via repression of pou5f3 family members in Xenopus., Young JJ, Kjolby RA, Kong NR, Monica SD, Harland RM., Development. April 1, 2014; 141 (8): 1683-93.                                                                


Cholesterol selectively activates canonical Wnt signalling over non-canonical Wnt signalling., Sheng R, Kim H, Lee H, Lee H, Xin Y, Chen Y, Tian W, Cui Y, Choi JC, Doh J, Han JK, Cho W., Nat Commun. July 15, 2014; 5 4393.              


Custos controls β-catenin to regulate head development during vertebrate embryogenesis., Komiya Y, Mandrekar N, Sato A, Dawid IB, Habas R., Proc Natl Acad Sci U S A. September 9, 2014; 111 (36): 13099-104.                                


Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression., Shi J, Zhao Y, Galati D, Winey M, Klymkowsky MW., Dev Biol. November 15, 2014; 395 (2): 287-98.                    


Xenopus laevis FGF receptor substrate 3 (XFrs3) is important for eye development and mediates Pax6 expression in lens placode through its Shp2-binding sites., Kim YJ, Bahn M, Kim YH, Shin JY, Cheong SW, Ju BG, Kim WS, Yeo CY., Dev Biol. January 1, 2015; 397 (1): 129-39.                                          


Methylmercury exposure during early Xenopus laevis development affects cell proliferation and death but not neural progenitor specification., Huyck RW, Nagarkar M, Olsen N, Clamons SE, Saha MS., Neurotoxicol Teratol. January 1, 2015; 47 102-13.                


A novel function for Egr4 in posterior hindbrain development., Bae CJ, Jeong J, Saint-Jeannet JP., Sci Rep. January 12, 2015; 5 7750.                              


The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation., Acosta H, Iliev D, Grahn TH, Gouignard N, Maccarana M, Griesbach J, Herzmann S, Sagha M, Climent M, Pera EM., Development. March 15, 2015; 142 (6): 1146-58.                                    


RMND5 from Xenopus laevis is an E3 ubiquitin-ligase and functions in early embryonic forebrain development., Pfirrmann T, Villavicencio-Lorini P, Subudhi AK, Menssen R, Wolf DH, Hollemann T., PLoS One. March 16, 2015; 10 (3): e0120342.                      


The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway., Luehders K, Sasai N, Davaapil H, Kurosawa-Yoshida M, Hiura H, Brah T, Ohnuma S., Development. October 1, 2015; 142 (19): 3351-61.                              

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