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Summary Expression Phenotypes Gene Literature (144) GO Terms (9) Nucleotides (27) Proteins (16) Interactants (960) Wiki
XB-GENEPAGE-6458521

Papers associated with nodal3.2



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Bone morphogenetic protein 15 (BMP15) acts as a BMP and Wnt inhibitor during early embryogenesis., Di Pasquale E, Brivanlou AH., J Biol Chem. September 18, 2009; 284 (38): 26127-36.                        

Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1., Louie SH, Yang XY, Conrad WH, Muster J, Angers S, Moon RT, Cheyette BN., PLoS One. January 1, 2009; 4 (2): e4310.                    

Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6., Wu G, Huang H, Garcia Abreu J, He X., PLoS One. January 1, 2009; 4 (3): e4926.              

Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation., Cha SW, Tadjuidje E, Tao Q, Tao Q, Wylie C, Heasman J., Development. November 1, 2008; 135 (22): 3719-29.        

Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL., Chitalia VC, Foy RL, Bachschmid MM, Zeng L, Panchenko MV, Zhou MI, Bharti A, Seldin DC, Lecker SH, Dominguez I, Cohen HT., Nat Cell Biol. October 1, 2008; 10 (10): 1208-16.        

Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements., Kim GH, Her JH, Han JK., J Cell Biol. September 22, 2008; 182 (6): 1073-82.          

Extracellular regulation of developmental cell signaling by XtSulf1., Freeman SD, Moore WM, Guiral EC, Holme AD, Turnbull JE, Pownall ME., Dev Biol. August 15, 2008; 320 (2): 436-45.            

Wise retained in the endoplasmic reticulum inhibits Wnt signaling by reducing cell surface LRP6., Guidato S, Itasaki N., Dev Biol. October 15, 2007; 310 (2): 250-63.                

Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings., Furushima K, Yamamoto A, Nagano T, Shibata M, Miyachi H, Abe T, Ohshima N, Kiyonari H, Aizawa S., Dev Biol. June 15, 2007; 306 (2): 480-92.  

Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo., Bryja V, Gradl D, Schambony A, Arenas E, Schulte G., Proc Natl Acad Sci U S A. April 17, 2007; 104 (16): 6690-5.  

Wnt11/beta-catenin signaling in both oocytes and early embryos acts through LRP6-mediated regulation of axin., Kofron M, Birsoy B, Houston D, Tao Q, Tao Q, Wylie C, Heasman J., Development. February 1, 2007; 134 (3): 503-13.      

Monomeric mature protein of Nodal-related 3 activates Xbra expression., Haramoto Y, Takahashi S, Asashima M., Dev Genes Evol. January 1, 2007; 217 (1): 29-37.

Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides., Rana AA, Collart C, Gilchrist MJ, Smith JC., PLoS Genet. November 17, 2006; 2 (11): e193.                                    

Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity., Ellies DL, Viviano B, McCarthy J, Rey JP, Itasaki N, Saunders S, Krumlauf R., J Bone Miner Res. November 1, 2006; 21 (11): 1738-49.              

Jun NH2-terminal kinase (JNK) prevents nuclear beta-catenin accumulation and regulates axis formation in Xenopus embryos., Liao G, Tao Q, Tao Q, Kofron M, Chen JS, Schloemer A, Davis RJ, Hsieh JC, Wylie C, Heasman J, Kuan CY., Proc Natl Acad Sci U S A. October 31, 2006; 103 (44): 16313-8.                    

Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal., Zamparini AL, Watts T, Gardner CE, Tomlinson SR, Johnston GI, Brickman JM., Development. September 1, 2006; 133 (18): 3709-22.                                    

NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)., Yamada M, Ohnishi J, Ohkawara B, Iemura S, Satoh K, Hyodo-Miura J, Kawachi K, Natsume T, Shibuya H., J Biol Chem. July 28, 2006; 281 (30): 20749-20760.                    

Maternal XTcf1 and XTcf4 have distinct roles in regulating Wnt target genes., Standley HJ, Destrée O, Kofron M, Wylie C, Heasman J., Dev Biol. January 15, 2006; 289 (2): 318-28.  

The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo., Chen C, Ware SM, Sato A, Houston-Hawkins DE, Habas R, Matzuk MM, Shen MM, Brown CW., Development. January 1, 2006; 133 (2): 319-29.              

Vg 1 is an essential signaling molecule in Xenopus development., Birsoy B, Kofron M, Schaible K, Wylie C, Heasman J., Development. January 1, 2006; 133 (1): 15-20.    

Xnr2 and Xnr5 unprocessed proteins inhibit Wnt signaling upstream of dishevelled., Onuma Y, Takahashi S, Haramoto Y, Tanegashima K, Yokota C, Whitman M, Asashima M., Dev Dyn. December 1, 2005; 234 (4): 900-10.          

Maternal Xenopus Zic2 negatively regulates Nodal-related gene expression during anteroposterior patterning., Houston DW, Wylie C., Development. November 1, 2005; 132 (21): 4845-55.              

Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/beta-catenin signaling., Swain RK, Katoh M, Medina A, Steinbeisser H., Cell Commun Signal. October 19, 2005; 3 12.          

The novel Smad-interacting protein Smicl regulates Chordin expression in the Xenopus embryo., Collart C, Verschueren K, Rana A, Smith JC, Huylebroeck D., Development. October 1, 2005; 132 (20): 4575-86.        

Subcellular localization and signaling properties of dishevelled in developing vertebrate embryos., Park TJ, Gray RS, Sato A, Habas R, Wallingford JB., Curr Biol. June 7, 2005; 15 (11): 1039-44.                

Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets., Park JI, Kim SW, Lyons JP, Ji H, Nguyen TT, Cho K, Barton MC, Deroo T, Vleminckx K, Vleminckx K, Moon RT, McCrea PD., Dev Cell. June 1, 2005; 8 (6): 843-54.            

Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development., Ossipova O, Dhawan S, Sokol S, Green JB., Dev Cell. June 1, 2005; 8 (6): 829-41.    

XIC is required for Siamois activity and dorsoanterior development., Snider L, Tapscott SJ., Mol Cell Biol. June 1, 2005; 25 (12): 5061-72.

Depletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structures., Khokha MK, Yeh J, Grammer TC, Harland RM., Dev Cell. March 1, 2005; 8 (3): 401-11.                          

XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGFbeta proteins in Xenopus development., Birsoy B, Berg L, Williams PH, Smith JC, Wylie CC, Christian JL, Heasman J., Development. February 1, 2005; 132 (3): 591-602.                      

Olfactory and lens placode formation is controlled by the hedgehog-interacting protein (Xhip) in Xenopus., Cornesse Y, Pieler T, Hollemann T., Dev Biol. January 15, 2005; 277 (2): 296-315.                          

Negative regulation of Smad2 by PIASy is required for proper Xenopus mesoderm formation., Daniels M, Shimizu K, Zorn AM, Ohnuma S., Development. November 1, 2004; 131 (22): 5613-26.                                

New roles for FoxH1 in patterning the early embryo., Kofron M, Puck H, Standley H, Wylie C, Old R, Whitman M, Heasman J., Development. October 1, 2004; 131 (20): 5065-78.              

The involvement of Frodo in TCF-dependent signaling and neural tissue development., Hikasa H, Sokol SY., Development. October 1, 2004; 131 (19): 4725-34.      

Patterning and tissue movements in a novel explant preparation of the marginal zone of Xenopus laevis., Davidson LA, Keller R, DeSimone D., Gene Expr Patterns. July 1, 2004; 4 (4): 457-66.        

Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus., Kuroda H, Wessely O, De Robertis EM., PLoS Biol. May 1, 2004; 2 (5): E92.                

Connective-tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex., Mercurio S, Latinkic B, Itasaki N, Krumlauf R, Smith JC., Development. May 1, 2004; 131 (9): 2137-47.                    

Xenopus tropicalis nodal-related gene 3 regulates BMP signaling: an essential role for the pro-region., Haramoto Y, Tanegashima K, Onuma Y, Takahashi S, Sekizaki H, Asashima M., Dev Biol. January 1, 2004; 265 (1): 155-68.              

PP2A:B56epsilon is required for Wnt/beta-catenin signaling during embryonic development., Yang J, Wu J, Tan C, Klein PS., Development. December 1, 2003; 130 (23): 5569-78.            

Wise, a context-dependent activator and inhibitor of Wnt signalling., Itasaki N, Jones CM, Mercurio S, Rowe A, Domingos PM, Smith JC, Krumlauf R., Development. September 1, 2003; 130 (18): 4295-305.                

PKC delta is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements., Kinoshita N, Iioka H, Miyakoshi A, Ueno N., Genes Dev. July 1, 2003; 17 (13): 1663-76.                    

Flamingo, a cadherin-type receptor involved in the Drosophila planar polarity pathway, can block signaling via the canonical wnt pathway in Xenopus laevis., Morgan R, El-Kadi AM, Theokli C., Int J Dev Biol. May 1, 2003; 47 (4): 245-52.              

A novel role for a nodal-related protein; Xnr3 regulates convergent extension movements via the FGF receptor., Yokota C, Kofron M, Zuck M, Houston DW, Isaacs H, Asashima M, Wylie CC, Heasman J., Development. May 1, 2003; 130 (10): 2199-212.    

Nodal signaling in Xenopus gastrulae is cell-autonomous and patterned by beta-catenin., Hashimoto-Partyka MK, Yuge M, Cho KW., Dev Biol. January 1, 2003; 253 (1): 125-38.                    

Lefty-dependent inhibition of Nodal- and Wnt-responsive organizer gene expression is essential for normal gastrulation., Branford WW, Yost HJ., Curr Biol. December 23, 2002; 12 (24): 2136-41.              

The roles of three signaling pathways in the formation and function of the Spemann Organizer., Xanthos JB, Kofron M, Tao Q, Tao Q, Schaible K, Wylie C, Heasman J., Development. September 1, 2002; 129 (17): 4027-43.                  

Repression of organizer genes in dorsal and ventral Xenopus cells mediated by maternal XTcf3., Houston DW, Kofron M, Resnik E, Langland R, Destree O, Wylie C, Heasman J., Development. September 1, 2002; 129 (17): 4015-25.          

Multiple interactions between maternally-activated signalling pathways control Xenopus nodal-related genes., Rex M, Hilton E, Old R., Int J Dev Biol. March 1, 2002; 46 (2): 217-26.

Multiple nodal-related genes act coordinately in Xenopus embryogenesis., Onuma Y, Takahashi S, Yokota C, Asashima M., Dev Biol. January 1, 2002; 241 (1): 94-105.

The Wnt/beta-catenin pathway posteriorizes neural tissue in Xenopus by an indirect mechanism requiring FGF signalling., Domingos PM, Itasaki N, Jones CM, Mercurio S, Sargent MG, Smith JC, Krumlauf R., Dev Biol. November 1, 2001; 239 (1): 148-60.              

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