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Summary Expression Phenotypes Gene Literature (226) GO Terms (6) Nucleotides (305) Proteins (73) Interactants (445) Wiki
XB-GENEPAGE-921634

Papers associated with gnao1



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Regulation of the voltage-insensitive step of HERG activation by extracellular pH., Zhou Q, Bett GC., Am J Physiol Heart Circ Physiol. June 1, 2010; 298 (6): H1710-8.

Modification of hERG1 channel gating by Cd2+., Abbruzzese J, Sachse FB, Tristani-Firouzi M, Sanguinetti MC., J Gen Physiol. August 1, 2010; 136 (2): 203-24.                                        

Current inhibition of human EAG1 potassium channels by the Ca2+ binding protein S100B., Sahoo N, Tröger J, Heinemann SH, Schönherr R., FEBS Lett. September 24, 2010; 584 (18): 3896-900.

Inner/Outer nuclear membrane fusion in nuclear pore assembly: biochemical demonstration and molecular analysis., Fichtman B, Ramos C, Rasala B, Harel A, Forbes DJ., Mol Biol Cell. December 1, 2010; 21 (23): 4197-211.                

Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643., Grunnet M, Abbruzzese J, Sachse FB, Sanguinetti MC., Mol Pharmacol. January 1, 2011; 79 (1): 1-9.

hERG potassium channel gating is mediated by N- and C-terminal region interactions., Gustina AS, Trudeau MC., J Gen Physiol. March 1, 2011; 137 (3): 315-25.              

Shh signalling restricts the expression of Gcm2 and controls the position of the developing parathyroids., Grevellec A, Graham A, Tucker AS., Dev Biol. May 15, 2011; 353 (2): 194-205.

hERGAPDbase: a database documenting hERG channel inhibitory potentials and APD-prolongation activities of chemical compounds., Hishigaki H, Kuhara S., Database (Oxford). May 17, 2011; 2011 bar017.            

Demonstration of physical proximity between the N terminus and the S4-S5 linker of the human ether-a-go-go-related gene (hERG) potassium channel., de la Peña P, Alonso-Ron C, Machín A, Fernández-Trillo J, Carretero L, Domínguez P, Barros F., J Biol Chem. May 27, 2011; 286 (21): 19065-75.

Differential effects of ginsenoside metabolites on HERG k channel currents., Choi SH, Shin TJ, Hwang SH, Lee BH, Kang J, Kim HJ, Oh JW, Bae CS, Lee SH, Nah SY., J Ginseng Res. June 1, 2011; 35 (2): 191-9.        

Ginsenoside Rg(3) decelerates hERG K(+) channel deactivation through Ser631 residue interaction., Choi SH, Shin TJ, Hwang SH, Lee BH, Kang J, Kim HJ, Jo SH, Choe H, Nah SY., Eur J Pharmacol. August 1, 2011; 663 (1-3): 59-67.

Blockade of permeation by potassium but normal gating of the G628S nonconducting hERG channel mutant., Es-Salah-Lamoureux Z, Xiong PY, Goodchild SJ, Ahern CA, Fedida D., Biophys J. August 3, 2011; 101 (3): 662-70.

Effects of the histamine H(1) receptor antagonist hydroxyzine on hERG K(+) channels and cardiac action potential duration., Lee BH, Lee SH, Chu D, Hyun JW, Choe H, Choi BH, Jo SH., Acta Pharmacol Sin. September 1, 2011; 32 (9): 1128-37.                  

Split-inteins for simultaneous, site-specific conjugation of quantum dots to multiple protein targets in vivo., Charalambous A, Antoniades I, Christodoulou N, Skourides PA., J Nanobiotechnology. September 15, 2011; 9 37.              

Molecular determinants for activation of human ether-à-go-go-related gene 1 potassium channels by 3-nitro-n-(4-phenoxyphenyl) benzamide., Garg V, Stary-Weinzinger A, Sachse F, Sanguinetti MC., Mol Pharmacol. October 1, 2011; 80 (4): 630-7.

Strong activation of ether-à-go-go-related gene 1 K+ channel isoforms by NS1643 in human embryonic kidney 293 and Chinese hamster ovary cells., Schuster AM, Glassmeier G, Bauer CK., Mol Pharmacol. November 1, 2011; 80 (5): 930-42.

Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway., Ferrer T, Cordero-Morales JF, Arias M, Ficker E, Medovoy D, Perozo E, Tristani-Firouzi M., J Biol Chem. November 11, 2011; 286 (45): 39091-9.

A unified anatomy ontology of the vertebrate skeletal system., Dahdul WM, Balhoff JP, Blackburn DC, Diehl AD, Haendel MA, Hall BK, Lapp H, Lundberg JG, Mungall CJ, Ringwald M, Segerdell E, Van Slyke CE, Vickaryous MK, Westerfield M, Mabee PM., PLoS One. January 1, 2012; 7 (12): e51070.            

Pharmacophore modeling for hERG channel facilitation., Yamakawa Y, Furutani K, Inanobe A, Ohno Y, Kurachi Y., Biochem Biophys Res Commun. February 3, 2012; 418 (1): 161-6.

Identification and functional characterization of the novel human ether-a-go-go-related gene (hERG) R744P mutant associated with hereditary long QT syndrome 2., Aidery P, Kisselbach J, Gaspar H, Baldea I, Schweizer PA, Becker R, Katus HA, Thomas D., Biochem Biophys Res Commun. February 24, 2012; 418 (4): 830-5.

The Xenopus retinal ganglion cell as a model neuron to study the establishment of neuronal connectivity., McFarlane S, Lom B., Dev Neurobiol. April 1, 2012; 72 (4): 520-36.

Melatonin receptors are anatomically organized to modulate transmission specifically to cone pathways in the retina of Xenopus laevis., Wiechmann AF, Sherry DM., J Comp Neurol. April 15, 2012; 520 (6): 1115-27.                  

Neural crest delamination and migration: from epithelium-to-mesenchyme transition to collective cell migration., Theveneau E, Mayor R., Dev Biol. June 1, 2012; 366 (1): 34-54.

Proton block of the pore underlies the inhibition of hERG cardiac K+ channels during acidosis., Van Slyke AC, Cheng YM, Mafi P, Allard CR, Hull CM, Shi YP, Claydon TW., Am J Physiol Cell Physiol. June 15, 2012; 302 (12): C1797-806.

Acute alteration of cardiac ECG, action potential, I(Kr) and the human ether-a-go-go-related gene (hERG) K+ channel by PCB 126 and PCB 77., Park MH, Park WS, Jo SH., Toxicol Appl Pharmacol. July 1, 2012; 262 (1): 60-9.

Tuning of EAG K(+) channel inactivation: molecular determinants of amplification by mutations and a small molecule., Garg V, Sachse FB, Sanguinetti MC., J Gen Physiol. September 1, 2012; 140 (3): 307-24.                            

Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels., Tan PS, Perry MD, Ng CA, Vandenberg JI, Hill AP., J Gen Physiol. September 1, 2012; 140 (3): 293-306.                

A natural point mutation changes both target selectivity and mechanism of action of sea anemone toxins., Peigneur S, Béress L, Möller C, Marí F, Forssmann WG, Tytgat J., FASEB J. December 1, 2012; 26 (12): 5141-51.

Serotonin has early, cilia-independent roles in Xenopus left-right patterning., Vandenberg LN, Lemire JM, Levin M., Dis Model Mech. January 1, 2013; 6 (1): 261-8.    

Blocking of the human ether-à-go-go-related gene channel by imatinib mesylate., Dong Q, Fu XX, Du LL, Zhao N, Xia CK, Yu KW, Cheng LX, Du YM., Biol Pharm Bull. January 1, 2013; 36 (2): 268-75.

[Follicular cells of the amphibian ovary: origin, structure, and functions]., Konduktorova VV, Luchinskaia NN., Ontogenez. January 1, 2013; 44 (5): 316-30.

The eag domain regulates hERG channel inactivation gating via a direct interaction., Gustina AS, Trudeau MC., J Gen Physiol. February 1, 2013; 141 (2): 229-41.                  

Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates., Long HK, Sims D, Heger A, Blackledge NP, Kutter C, Wright ML, Grützner F, Odom DT, Patient R, Ponting CP, Klose RJ., Elife. February 26, 2013; 2 e00348.                  

Block of hERG K+ channel and prolongation of action potential duration by fluphenazine at submicromolar concentration., Hong HK, Lee BH, Park MH, Lee SH, Chu D, Kim WJ, Choe H, Hee Choi B, Jo SH., Eur J Pharmacol. February 28, 2013; 702 (1-3): 165-73.

Flavonoid regulation of EAG1 channels., Carlson AE, Brelidze TI, Zagotta WN., J Gen Physiol. March 1, 2013; 141 (3): 347-58.                  

ICA-105574 interacts with a common binding site to elicit opposite effects on inactivation gating of EAG and ERG potassium channels., Garg V, Stary-Weinzinger A, Sanguinetti MC., Mol Pharmacol. April 1, 2013; 83 (4): 805-13.

Mapping of interactions between the N- and C-termini and the channel core in HERG K+ channels., de la Peña P, Machín A, Fernández-Trillo J, Domínguez P, Barros F., Biochem J. May 1, 2013; 451 (3): 463-74.

External pH modulates EAG superfamily K+ channels through EAG-specific acidic residues in the voltage sensor., Kazmierczak M, Zhang X, Chen B, Mulkey DK, Shi Y, Wagner PG, Pivaroff-Ward K, Sassic JK, Bayliss DA, Jegla T., J Gen Physiol. June 1, 2013; 141 (6): 721-35.                        

The neutral, hydrophobic isoleucine at position I521 in the extracellular S4 domain of hERG contributes to channel gating equilibrium., Dou Y, Goodchild SJ, Velde RV, Wu Y, Fedida D., Am J Physiol Cell Physiol. August 15, 2013; 305 (4): C468-78.

Blockade of the human ether-a-go-go-related gene potassium channel by ketamine., Zhang P, Xing J, Luo A, Feng J, Liu Z, Gao C, Ma J., J Pharm Pharmacol. September 1, 2013; 65 (9): 1321-8.

Exotic models may offer unique opportunities to decipher specific scientific question: the case of Xenopus olfactory system., Gascuel J, Amano T., Anat Rec (Hoboken). September 1, 2013; 296 (9): 1453-61.    

Functional interactions of voltage sensor charges with an S2 hydrophobic plug in hERG channels., Cheng YM, Hull CM, Niven CM, Qi J, Allard CR, Claydon TW., J Gen Physiol. September 1, 2013; 142 (3): 289-303.                

Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels., Perry MD, Wong S, Ng CA, Vandenberg JI., J Gen Physiol. September 1, 2013; 142 (3): 275-88.                    

Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel., Park MH, Lee SH, Chu DH, Won KH, Choi BH, Choe H, Jo SH., J Pharmacol Sci. September 20, 2013; 123 (1): 67-77.

AMP-activated protein kinase regulates hERG potassium channel., Almilaji A, Munoz C, Elvira B, Fajol A, Pakladok T, Honisch S, Shumilina E, Lang F, Föller M., Pflugers Arch. November 1, 2013; 465 (11): 1573-82.

Up-regulation of hERG K⁺ channels by B-RAF., Pakladok T, Hosseinzadeh Z, Almilaji A, Lebedeva A, Shumilina E, Alesutan I, Lang F., PLoS One. January 1, 2014; 9 (1): e87457.          

Proline scan of the HERG channel S6 helix reveals the location of the intracellular pore gate., Thouta S, Sokolov S, Abe Y, Clark SJ, Cheng YM, Claydon TW., Biophys J. March 4, 2014; 106 (5): 1057-69.

Functional evolution of Erg potassium channel gating reveals an ancient origin for IKr., Martinson AS, van Rossum DB, Diatta FH, Layden MJ, Rhodes SA, Martindale MQ, Jegla T., Proc Natl Acad Sci U S A. April 15, 2014; 111 (15): 5712-7.

Sema6a and Plxna2 mediate spatially regulated repulsion within the developing eye to promote eye vesicle cohesion., Ebert AM, Childs SJ, Hehr CL, Cechmanek PB, McFarlane S., Development. June 1, 2014; 141 (12): 2473-82.

Natural products as potential human ether-a-go-go-related gene channel inhibitors - screening of plant-derived alkaloids., Schramm A, Saxena P, Chlebek J, Cahlíková L, Baburin I, Hering S, Hamburger M., Planta Med. June 1, 2014; 80 (8-9): 740-6.

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