zengjin huang - Publications

Publications (26)

XB-PERS-3401

Publications By zengjin huang

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Synthesis and Biological Evaluation of Novel Triazine Derivatives as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors., Wang X, Xiao H, Wang J, Huang Z, Peng G, Xie W, Bian X, Liu H, Shi C, Yang T, Li X, Gao J, Meng Y, Jiang Q, Chen W, Hu F, Wei N, Wang X, Zhang L, Wang K, Sun Q., J Med Chem. August 26, 2021; 64 (16): 12379-12396.
An In Vitro Study on Prestin Analog Gene in the Bullfrog Hearing Organs., Wang Z, Qian M, Wang Q, Liu H, Wu H, Huang Z., Neural Plast. July 2, 2020; 2020 3570732.
Identification of Shaker K+ channel family members in Rosaceae and a functional exploration of PbrKAT1., Chen G, Chen Q, Qi K, Xie Z, Yin H, Wang P, Wang R, Huang Z, Zhang S, Wang L, Wu J., Planta. December 1, 2019; 250 (6): 1911-1925.
Chemical conversion of nicotinamide into type I positive allosteric modulator of α7 nAChRs., Li X, Xie W, Wang X, Huang Z, Bian X, Wang K, Sun Q., Bioorg Med Chem Lett. August 1, 2019; 29 (15): 1928-1933.
Design and Synthesis of Novel Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors with the Ability To Rescue Auditory Gating Deficit in Mice., Li Y, Sun L, Yang T, Jiao W, Tang J, Huang X, Huang Z, Meng Y, Luo L, Wang X, Bian X, Zhang F, Wang K, Sun Q., J Med Chem. January 10, 2019; 62 (1): 159-173.
A Label-free Multicolor Optical Surface Tomography (ALMOST) imaging method for nontransparent 3D samples., Kerstens A, Corthout N, Pavie B, Huang Z, Vernaillen F, Vande Velde G, Munck S., BMC Biol. January 7, 2019; 17 (1): 1.
Characterization of a Single Genomic Locus Encoding the Clustered Protocadherin Receptor Diversity in Xenopus tropicalis., Etlioglu HE, Sun W, Huang Z, Chen W, Schmucker D., G3 (Bethesda). August 9, 2016; 6 (8): 2309-18.
The Male Abnormal Gene Family 21 (Mab21) Members Regulate Eye Development., Huang ZX, Xiang JW, Zhou L, Nie Q, Wang L, Chen ZG, Hu XH, Xiao Y, Qing WJ, Liu YF, Sun Q, Tang XC, Liu FY, Luo ZW, Liu WB, Li DW., Curr Mol Med. January 1, 2016; 16 (7): 660-667.
Complicated behavior of G-quadruplexes and evaluating G-quadruplexes' ligands in various systems mimicking cellular circumstance., Wang SK, Su HF, Gu YC, Lin SL, Tan JH, Huang ZS, Ou TM., Biochem Biophys Rep. October 3, 2015; 5 439-447.
Different KChIPs compete for heteromultimeric assembly with pore-forming Kv4 subunits., Zhou J, Tang Y, Zheng Q, Li M, Yuan T, Chen L, Huang Z, Wang K., Biophys J. June 2, 2015; 108 (11): 2658-69.
Tumor suppressor p16(INK4a) inhibits cancer cell growth by downregulating eEF1A2 through a direct interaction., Lee MH, Choi BY, Cho YY, Lee SY, Huang Z, Kundu JK, Kim MO, Kim DJ, Bode AM, Surh YJ, Dong Z., J Cell Sci. April 15, 2013; 126 (Pt 8): 1744-52.
[Establishment of a targeting protein for Xenopus kinesin-like protein 2 C' terminal SBP-3 x Flag tagged HCT 116 colorectal cancer cell model]., Huang ZB, Zhang ZY, Zhang XD, Miao SY, Wang LF, Du RL., Zhongguo Yi Xue Ke Xue Yuan Xue Bao. December 1, 2011; 33 (6): 624-8.
Light-induced tyrosine phosphorylation of rod outer segment membrane proteins regulate the translocation, membrane binding and activation of type II α phosphatidylinositol-5-phosphate 4-kinase., Huang Z, Anderson RE, Cao W, Wiechmann AF, Rajala RV., Neurochem Res. April 1, 2011; 36 (4): 627-35.
Phosphopeptide screen uncovers novel phosphorylation sites of Nedd4-2 that potentiate its inhibition of the epithelial Na+ channel., Hallows KR, Bhalla V, Oyster NM, Wijngaarden MA, Lee JK, Li H, Chandran S, Xia X, Huang Z, Chalkley RJ, Burlingame AL, Pearce D., J Biol Chem. July 9, 2010; 285 (28): 21671-8.
Functional expression of an arachnid sodium channel reveals residues responsible for tetrodotoxin resistance in invertebrate sodium channels., Du Y, Nomura Y, Liu Z, Huang ZY, Dong K., J Biol Chem. December 4, 2009; 284 (49): 33869-75.
Effect of a fluvalinate-resistance-associated sodium channel mutation from varroa mites on cockroach sodium channel sensitivity to fluvalinate, a pyrethroid insecticide., Liu Z, Tan J, Huang ZY, Dong K., Insect Biochem Mol Biol. November 1, 2006; 36 (11): 885-9.
Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding., Tan J, Liu Z, Wang R, Huang ZY, Chen AC, Gurevitz M, Dong K., Mol Pharmacol. February 1, 2005; 67 (2): 513-22.
Protein 14-3-3zeta binds to protein phosphatase PP1gamma2 in bovine epididymal spermatozoa., Huang Z, Myers K, Khatra B, Vijayaraghavan S., Biol Reprod. July 1, 2004; 71 (1): 177-84.
A role for cofactor-cofactor and cofactor-histone interactions in targeting p300, SWI/SNF and Mediator for transcription., Huang ZQ, Li J, Sachs LM, Cole PA, Wong J., EMBO J. May 1, 2003; 22 (9): 2146-55.
Involvement of histone methylation and phosphorylation in regulation of transcription by thyroid hormone receptor., Li J, Lin Q, Yoon HG, Huang ZQ, Strahl BD, Allis CD, Wong J., Mol Cell Biol. August 1, 2002; 22 (16): 5688-97.
AR possesses an intrinsic hormone-independent transcriptional activity., Huang ZQ, Li J, Wong J., Mol Endocrinol. May 1, 2002; 16 (5): 924-37.
Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor., Wang H, Huang ZQ, Xia L, Feng Q, Erdjument-Bromage H, Strahl BD, Briggs SD, Allis CD, Wong J, Tempst P, Zhang Y., Science. August 3, 2001; 293 (5531): 853-7.
Coupling of calcium receptors to inositol phosphate and cyclic AMP generation in mammalian cells and Xenopus laevis oocytes and immunodetection of receptor protein by region-specific antipeptide antisera., Chang W, Pratt S, Chen TH, Nemeth E, Huang Z, Shoback D., J Bone Miner Res. April 1, 1998; 13 (4): 570-80.
The N-terminal region of the third intracellular loop of the parathyroid hormone (PTH)/PTH-related peptide receptor is critical for coupling to cAMP and inositol phosphate/Ca2+ signal transduction pathways., Huang Z, Chen Y, Pratt S, Chen TH, Bambino T, Nissenson RA, Shoback DM., J Biol Chem. December 27, 1996; 271 (52): 33382-9.
Mutational analysis of the cytoplasmic tail of the G protein-coupled receptor for parathyroid hormone (PTH) and PTH-related protein: effects on receptor expression and signaling., Huang Z, Chen Y, Pratt S, Chen TH, Bambino T, Shoback DM, Nissenson RA., Mol Endocrinol. September 1, 1995; 9 (9): 1240-9.
Pharmacological profile of NPC 17742 [2R,4R,5S-(2-amino-4,5-(1, 2-cyclohexyl)-7-phosphonoheptanoic acid)], a potent, selective and competitive N-methyl-D-aspartate receptor antagonist., Ferkany JW, Hamilton GS, Patch RJ, Huang Z, Borosky SA, Bednar DL, Jones BE, Zubrowski R, Willetts J, Karbon EW., J Pharmacol Exp Ther. January 1, 1993; 264 (1): 256-64.

Synthesis and Biological Evaluation of Novel Triazine Derivatives as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors., Wang X, Xiao H, Wang J, Huang Z, Peng G, Xie W, Bian X, Liu H, Shi C, Yang T, Li X, Gao J, Meng Y, Jiang Q, Chen W, Hu F, Wei N, Wang X, Zhang L, Wang K, Sun Q., J Med Chem. August 26, 2021; 64 (16): 12379-12396.

An In Vitro Study on Prestin Analog Gene in the Bullfrog Hearing Organs., Wang Z, Qian M, Wang Q, Liu H, Wu H, Huang Z., Neural Plast. July 2, 2020; 2020 3570732.

Identification of Shaker K+ channel family members in Rosaceae and a functional exploration of PbrKAT1., Chen G, Chen Q, Qi K, Xie Z, Yin H, Wang P, Wang R, Huang Z, Zhang S, Wang L, Wu J., Planta. December 1, 2019; 250 (6): 1911-1925.

Chemical conversion of nicotinamide into type I positive allosteric modulator of α7 nAChRs., Li X, Xie W, Wang X, Huang Z, Bian X, Wang K, Sun Q., Bioorg Med Chem Lett. August 1, 2019; 29 (15): 1928-1933.

Design and Synthesis of Novel Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors with the Ability To Rescue Auditory Gating Deficit in Mice., Li Y, Sun L, Yang T, Jiao W, Tang J, Huang X, Huang Z, Meng Y, Luo L, Wang X, Bian X, Zhang F, Wang K, Sun Q., J Med Chem. January 10, 2019; 62 (1): 159-173.

A Label-free Multicolor Optical Surface Tomography (ALMOST) imaging method for nontransparent 3D samples., Kerstens A, Corthout N, Pavie B, Huang Z, Vernaillen F, Vande Velde G, Munck S., BMC Biol. January 7, 2019; 17 (1): 1.

Characterization of a Single Genomic Locus Encoding the Clustered Protocadherin Receptor Diversity in Xenopus tropicalis., Etlioglu HE, Sun W, Huang Z, Chen W, Schmucker D., G3 (Bethesda). August 9, 2016; 6 (8): 2309-18.

The Male Abnormal Gene Family 21 (Mab21) Members Regulate Eye Development., Huang ZX, Xiang JW, Zhou L, Nie Q, Wang L, Chen ZG, Hu XH, Xiao Y, Qing WJ, Liu YF, Sun Q, Tang XC, Liu FY, Luo ZW, Liu WB, Li DW., Curr Mol Med. January 1, 2016; 16 (7): 660-667.

Complicated behavior of G-quadruplexes and evaluating G-quadruplexes' ligands in various systems mimicking cellular circumstance., Wang SK, Su HF, Gu YC, Lin SL, Tan JH, Huang ZS, Ou TM., Biochem Biophys Rep. October 3, 2015; 5 439-447.

Different KChIPs compete for heteromultimeric assembly with pore-forming Kv4 subunits., Zhou J, Tang Y, Zheng Q, Li M, Yuan T, Chen L, Huang Z, Wang K., Biophys J. June 2, 2015; 108 (11): 2658-69.

Tumor suppressor p16(INK4a) inhibits cancer cell growth by downregulating eEF1A2 through a direct interaction., Lee MH, Choi BY, Cho YY, Lee SY, Huang Z, Kundu JK, Kim MO, Kim DJ, Bode AM, Surh YJ, Dong Z., J Cell Sci. April 15, 2013; 126 (Pt 8): 1744-52.

[Establishment of a targeting protein for Xenopus kinesin-like protein 2 C' terminal SBP-3 x Flag tagged HCT 116 colorectal cancer cell model]., Huang ZB, Zhang ZY, Zhang XD, Miao SY, Wang LF, Du RL., Zhongguo Yi Xue Ke Xue Yuan Xue Bao. December 1, 2011; 33 (6): 624-8.

Light-induced tyrosine phosphorylation of rod outer segment membrane proteins regulate the translocation, membrane binding and activation of type II α phosphatidylinositol-5-phosphate 4-kinase., Huang Z, Anderson RE, Cao W, Wiechmann AF, Rajala RV., Neurochem Res. April 1, 2011; 36 (4): 627-35.

Phosphopeptide screen uncovers novel phosphorylation sites of Nedd4-2 that potentiate its inhibition of the epithelial Na+ channel., Hallows KR, Bhalla V, Oyster NM, Wijngaarden MA, Lee JK, Li H, Chandran S, Xia X, Huang Z, Chalkley RJ, Burlingame AL, Pearce D., J Biol Chem. July 9, 2010; 285 (28): 21671-8.

Functional expression of an arachnid sodium channel reveals residues responsible for tetrodotoxin resistance in invertebrate sodium channels., Du Y, Nomura Y, Liu Z, Huang ZY, Dong K., J Biol Chem. December 4, 2009; 284 (49): 33869-75.

Effect of a fluvalinate-resistance-associated sodium channel mutation from varroa mites on cockroach sodium channel sensitivity to fluvalinate, a pyrethroid insecticide., Liu Z, Tan J, Huang ZY, Dong K., Insect Biochem Mol Biol. November 1, 2006; 36 (11): 885-9.

Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding., Tan J, Liu Z, Wang R, Huang ZY, Chen AC, Gurevitz M, Dong K., Mol Pharmacol. February 1, 2005; 67 (2): 513-22.

Protein 14-3-3zeta binds to protein phosphatase PP1gamma2 in bovine epididymal spermatozoa., Huang Z, Myers K, Khatra B, Vijayaraghavan S., Biol Reprod. July 1, 2004; 71 (1): 177-84.

A role for cofactor-cofactor and cofactor-histone interactions in targeting p300, SWI/SNF and Mediator for transcription., Huang ZQ, Li J, Sachs LM, Cole PA, Wong J., EMBO J. May 1, 2003; 22 (9): 2146-55.

Involvement of histone methylation and phosphorylation in regulation of transcription by thyroid hormone receptor., Li J, Lin Q, Yoon HG, Huang ZQ, Strahl BD, Allis CD, Wong J., Mol Cell Biol. August 1, 2002; 22 (16): 5688-97.

AR possesses an intrinsic hormone-independent transcriptional activity., Huang ZQ, Li J, Wong J., Mol Endocrinol. May 1, 2002; 16 (5): 924-37.

Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor., Wang H, Huang ZQ, Xia L, Feng Q, Erdjument-Bromage H, Strahl BD, Briggs SD, Allis CD, Wong J, Tempst P, Zhang Y., Science. August 3, 2001; 293 (5531): 853-7.

Coupling of calcium receptors to inositol phosphate and cyclic AMP generation in mammalian cells and Xenopus laevis oocytes and immunodetection of receptor protein by region-specific antipeptide antisera., Chang W, Pratt S, Chen TH, Nemeth E, Huang Z, Shoback D., J Bone Miner Res. April 1, 1998; 13 (4): 570-80.

The N-terminal region of the third intracellular loop of the parathyroid hormone (PTH)/PTH-related peptide receptor is critical for coupling to cAMP and inositol phosphate/Ca2+ signal transduction pathways., Huang Z, Chen Y, Pratt S, Chen TH, Bambino T, Nissenson RA, Shoback DM., J Biol Chem. December 27, 1996; 271 (52): 33382-9.

Mutational analysis of the cytoplasmic tail of the G protein-coupled receptor for parathyroid hormone (PTH) and PTH-related protein: effects on receptor expression and signaling., Huang Z, Chen Y, Pratt S, Chen TH, Bambino T, Shoback DM, Nissenson RA., Mol Endocrinol. September 1, 1995; 9 (9): 1240-9.

Pharmacological profile of NPC 17742 [2R,4R,5S-(2-amino-4,5-(1, 2-cyclohexyl)-7-phosphonoheptanoic acid)], a potent, selective and competitive N-methyl-D-aspartate receptor antagonist., Ferkany JW, Hamilton GS, Patch RJ, Huang Z, Borosky SA, Bednar DL, Jones BE, Zubrowski R, Willetts J, Karbon EW., J Pharmacol Exp Ther. January 1, 1993; 264 (1): 256-64.

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