Laura A. Lee - Publications

Publications (12)

XB-PERS-3174

Publications By Laura A. Lee

???pagination.result.count???

???pagination.result.page??? 1

INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex., Mascibroda LG, Shboul M, Elrod ND, Colleaux L, Hamamy H, Huang KL, Peart N, Singh MK, Lee H, Merriman B, Jodoin JN, Sitaram P, Lee LA, Fathalla R, Al-Rawashdeh B, Ababneh O, El-Khateeb M, Escande-Beillard N, Nelson SF, Wu Y, Tong L, Kenney LJ, Roy S, Russell WK, Amiel J, Reversade B, Wagner EJ., Nat Commun. October 13, 2022; 13 (1): 6054.
Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling., Ng VH, Hang BI, Sawyer LM, Neitzel LR, Crispi EE, Rose KL, Popay TM, Zhong A, Lee LA, Tansey WP, Huppert S, Lee E., J Cell Sci. May 22, 2018; 131 (10):
Identification of a Paralog-Specific Notch1 Intracellular Domain Degron., Broadus MR, Chen TW, Neitzel LR, Ng VH, Jodoin JN, Lee LA, Salic A, Robbins DJ, Capobianco AJ, Patton JG, Huppert SS, Lee E., Cell Rep. May 31, 2016; 15 (9): 1920-9.
The Drosophila MCPH1-B isoform is a substrate of the APCCdh1 E3 ubiquitin ligase complex., Hainline SG, Rickmyre JL, Neitzel LR, Lee LA, Lee E., Biol Open. June 27, 2014; 3 (7): 669-76.
Screening for small molecule inhibitors of embryonic pathways: sometimes you gotta crack a few eggs., Hang BI, Thorne CA, Robbins DJ, Huppert SS, Lee LA, Lee E., Bioorg Med Chem. March 15, 2012; 20 (6): 1869-77.
XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signaling., Hanson AJ, Wallace HA, Freeman TJ, Beauchamp RD, Lee LA, Lee E., Mol Cell. March 9, 2012; 45 (5): 619-28.
A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts., Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wichaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, Lee LA, Robbins DJ, Huppert SS, Lee E., J Biomol Screen. October 1, 2011; 16 (9): 995-1006.
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α., Thorne CA, Hanson AJ, Schneider J, Tahinci E, Orton D, Cselenyi CS, Jernigan KK, Meyers KC, Hang BI, Waterson AG, Kim K, Melancon B, Ghidu VP, Sulikowski GA, LaFleur B, Salic A, Lee LA, Miller DM, Lee E., Nat Chem Biol. November 1, 2010; 6 (11): 829-36.
Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity., Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E., Sci Signal. May 11, 2010; 3 (121): ra37.
LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin., Cselenyi CS, Jernigan KK, Tahinci E, Thorne CA, Lee LA, Lee E., Proc Natl Acad Sci U S A. June 10, 2008; 105 (23): 8032-7.
Lrp6 is required for convergent extension during Xenopus gastrulation., Tahinci E, Thorne CA, Franklin JL, Salic A, Christian KM, Lee LA, Coffey RJ, Lee E., Development. November 1, 2007; 134 (22): 4095-106.
Drosophila genome-scale screen for PAN GU kinase substrates identifies Mat89Bb as a cell cycle regulator., Lee LA, Lee E, Anderson MA, Vardy L, Tahinci E, Ali SM, Kashevsky H, Benasutti M, Kirschner MW, Orr-Weaver TL., Dev Cell. March 1, 2005; 8 (3): 435-42.

INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex., Mascibroda LG, Shboul M, Elrod ND, Colleaux L, Hamamy H, Huang KL, Peart N, Singh MK, Lee H, Merriman B, Jodoin JN, Sitaram P, Lee LA, Fathalla R, Al-Rawashdeh B, Ababneh O, El-Khateeb M, Escande-Beillard N, Nelson SF, Wu Y, Tong L, Kenney LJ, Roy S, Russell WK, Amiel J, Reversade B, Wagner EJ., Nat Commun. October 13, 2022; 13 (1): 6054.

Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling., Ng VH, Hang BI, Sawyer LM, Neitzel LR, Crispi EE, Rose KL, Popay TM, Zhong A, Lee LA, Tansey WP, Huppert S, Lee E., J Cell Sci. May 22, 2018; 131 (10):

Identification of a Paralog-Specific Notch1 Intracellular Domain Degron., Broadus MR, Chen TW, Neitzel LR, Ng VH, Jodoin JN, Lee LA, Salic A, Robbins DJ, Capobianco AJ, Patton JG, Huppert SS, Lee E., Cell Rep. May 31, 2016; 15 (9): 1920-9.

The Drosophila MCPH1-B isoform is a substrate of the APCCdh1 E3 ubiquitin ligase complex., Hainline SG, Rickmyre JL, Neitzel LR, Lee LA, Lee E., Biol Open. June 27, 2014; 3 (7): 669-76.

Screening for small molecule inhibitors of embryonic pathways: sometimes you gotta crack a few eggs., Hang BI, Thorne CA, Robbins DJ, Huppert SS, Lee LA, Lee E., Bioorg Med Chem. March 15, 2012; 20 (6): 1869-77.

XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signaling., Hanson AJ, Wallace HA, Freeman TJ, Beauchamp RD, Lee LA, Lee E., Mol Cell. March 9, 2012; 45 (5): 619-28.

A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts., Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wichaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, Lee LA, Robbins DJ, Huppert SS, Lee E., J Biomol Screen. October 1, 2011; 16 (9): 995-1006.

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α., Thorne CA, Hanson AJ, Schneider J, Tahinci E, Orton D, Cselenyi CS, Jernigan KK, Meyers KC, Hang BI, Waterson AG, Kim K, Melancon B, Ghidu VP, Sulikowski GA, LaFleur B, Salic A, Lee LA, Miller DM, Lee E., Nat Chem Biol. November 1, 2010; 6 (11): 829-36.

Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity., Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E., Sci Signal. May 11, 2010; 3 (121): ra37.

LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin., Cselenyi CS, Jernigan KK, Tahinci E, Thorne CA, Lee LA, Lee E., Proc Natl Acad Sci U S A. June 10, 2008; 105 (23): 8032-7.

Lrp6 is required for convergent extension during Xenopus gastrulation., Tahinci E, Thorne CA, Franklin JL, Salic A, Christian KM, Lee LA, Coffey RJ, Lee E., Development. November 1, 2007; 134 (22): 4095-106.

Drosophila genome-scale screen for PAN GU kinase substrates identifies Mat89Bb as a cell cycle regulator., Lee LA, Lee E, Anderson MA, Vardy L, Tahinci E, Ali SM, Kashevsky H, Benasutti M, Kirschner MW, Orr-Weaver TL., Dev Cell. March 1, 2005; 8 (3): 435-42.

???pagination.result.page??? 1