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Profile Publications (54)
XB-PERS-2881

Publications By Hermona Soreq

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Transcriptional regulation of erythropoiesis. Fine tuning of combinatorial multi-domain elements., Perry C, Soreq H., Eur J Biochem. August 1, 2002; 269 (15): 3607-18.


In vivo and in vitro resistance to multiple anticholinesterases in Xenopus laevis tadpoles., Shapira M, Seidman S, Livni N, Soreq H., Toxicol Lett. December 28, 1998; 102-103 205-9.


Acetylcholinesterase enhances neurite growth and synapse development through alternative contributions of its hydrolytic capacity, core protein, and variable C termini., Sternfeld M, Ming G, Song H, Sela K, Timberg R, Poo M, Soreq H., J Neurosci. February 15, 1998; 18 (4): 1240-9.


Position effect variegations and brain-specific silencing in transgenic mice overexpressing human acetylcholinesterase variants., Sternfeld M, Patrick JD, Soreq H., J Physiol Paris. January 1, 1998; 92 (3-4): 249-55.


Genetic manipulations of cholinergic communication reveal trans-acting control mechanisms over acetylcholine receptors., Broide RS, Grifman M, Shapira M, Ginzberg D, Soreq H., J Recept Signal Transduct Res. January 1, 1997; 17 (1-3): 279-91.


Overlapping drug interaction sites of human butyrylcholinesterase dissected by site-directed mutagenesis., Loewenstein-Lichtenstein Y, Glick D, Gluzman N, Sternfeld M, Zakut H, Soreq H., Mol Pharmacol. December 1, 1996; 50 (6): 1423-31.


Transgenic expression of human acetylcholinesterase induces progressive cognitive deterioration in mice., Beeri R, Andres C, Lev-Lehman E, Timberg R, Huberman T, Shani M, Soreq H., Curr Biol. September 1, 1995; 5 (9): 1063-71.


Successive organophosphate inhibition and oxime reactivation reveals distinct responses of recombinant human cholinesterase variants., Schwarz M, Loewenstein-Lichtenstein Y, Glick D, Liao J, Norgaard-Pedersen B, Soreq H., Brain Res Mol Brain Res. July 1, 1995; 31 (1-2): 101-10.


Synaptic and epidermal accumulations of human acetylcholinesterase are encoded by alternative 3'-terminal exons., Seidman S, Sternfeld M, Ben Aziz-Aloya R, Timberg R, Kaufer-Nachum D, Soreq H., Mol Cell Biol. June 1, 1995; 15 (6): 2993-3002.


Transgenic engineering of neuromuscular junctions in Xenopus laevis embryos transiently overexpressing key cholinergic proteins., Shapira M, Seidman S, Sternfeld M, Timberg R, Kaufer D, Patrick J, Soreq H., Proc Natl Acad Sci U S A. September 13, 1994; 91 (19): 9072-6.


Overexpressed monomeric human acetylcholinesterase induces subtle ultrastructural modifications in developing neuromuscular junctions of Xenopus laevis embryos., Seidman S, Aziz-Aloya RB, Timberg R, Loewenstein Y, Velan B, Shafferman A, Liao J, Norgaard-Pedersen B, Brodbeck U, Soreq H., J Neurochem. May 1, 1994; 62 (5): 1670-81.


Site-directed mutagenesis of active site residues reveals plasticity of human butyrylcholinesterase in substrate and inhibitor interactions., Gnatt A, Loewenstein Y, Yaron A, Schwarz M, Soreq H., J Neurochem. February 1, 1994; 62 (2): 749-55.


Mutations and impaired expression in the ACHE and BCHE genes: neurological implications., Soreq H, Ehrlich G, Schwarz M, Loewenstein Y, Glick D, Zakut H., Biomed Pharmacother. January 1, 1994; 48 (5-6): 253-9.


Chimeric human cholinesterase. Identification of interaction sites responsible for recognition of acetyl- or butyrylcholinesterase-specific ligands., Loewenstein Y, Gnatt A, Neville LF, Soreq H., J Mol Biol. November 20, 1993; 234 (2): 289-96.


Structure-function relationship studies in human cholinesterases reveal genomic origins for individual variations in cholinergic drug responses., Loewenstein Y, Gnatt A, Neville LF, Zakut H, Soreq H., Prog Neuropsychopharmacol Biol Psychiatry. November 1, 1993; 17 (6): 905-26.


Expression of a human acetylcholinesterase promoter-reporter construct in developing neuromuscular junctions of Xenopus embryos., Ben Aziz-Aloya R, Seidman S, Timberg R, Sternfeld M, Zakut H, Soreq H., Proc Natl Acad Sci U S A. March 15, 1993; 90 (6): 2471-5.        


Intramolecular relationships in cholinesterases revealed by oocyte expression of site-directed and natural variants of human BCHE., Neville LF, Gnatt A, Loewenstein Y, Seidman S, Ehrlich G, Soreq H., EMBO J. April 1, 1992; 11 (4): 1641-9.


Xenopus oocyte microinjection: from gene to protein., Soreq H, Seidman S., Methods Enzymol. January 1, 1992; 207 225-65.


Anionic site interactions in human butyrylcholinesterase disrupted by two single point mutations., Neville LF, Gnatt A, Padan R, Seidman S, Soreq H., J Biol Chem. December 5, 1990; 265 (34): 20735-8.


Aspartate-70 to glycine substitution confers resistance to naturally occurring and synthetic anionic-site ligands on in-ovo produced human butyrylcholinesterase., Neville LF, Gnatt A, Loewenstein Y, Soreq H., J Neurosci Res. December 1, 1990; 27 (4): 452-60.


Manipulations of cholinesterase gene expression modulate murine megakaryocytopoiesis in vitro., Patinkin D, Seidman S, Eckstein F, Benseler F, Zakut H, Soreq H., Mol Cell Biol. November 1, 1990; 10 (11): 6046-50.


Acetylcholinesterase and butyrylcholinesterase genes coamplify in primary ovarian carcinomas., Zakut H, Ehrlich G, Ayalon A, Prody CA, Malinger G, Seidman S, Ginzberg D, Kehlenbach R, Soreq H., J Clin Invest. September 1, 1990; 86 (3): 900-8.


Coinjection of Xenopus oocytes with cDNA-produced and native mRNAs: a molecular biological approach to the tissue-specific processing of human cholinesterases., Seidman S, Soreq H., Int Rev Neurobiol. January 1, 1990; 32 107-39.


trans activation of rat phosphoenolpyruvate carboxykinase (GTP) gene expression by micro-coinjection of rat liver mRNA in Xenopus laevis oocytes., Benvenisty N, Shoshani T, Farkash Y, Soreq H, Reshef L., Mol Cell Biol. November 1, 1989; 9 (11): 5244-7.


Efficient functioning of plant promoters and poly(A) sites in Xenopus oocytes., Ballas N, Broido S, Soreq H, Loyter A., Nucleic Acids Res. October 11, 1989; 17 (19): 7891-903.


Tissue-specific processing and polarized compartmentalization of clone-produced cholinesterase in microinjected Xenopus oocytes., Dreyfus PA, Seidman S, Pincon-Raymond M, Murawsky M, Rieger F, Schejter E, Zakut H, Soreq H., Cell Mol Neurobiol. September 1, 1989; 9 (3): 323-41.


Expression and tissue-specific assembly of human butyrylcholine esterase in microinjected Xenopus laevis oocytes., Soreq H, Seidman S, Dreyfus PA, Zevin-Sonkin D, Zakut H., J Biol Chem. June 25, 1989; 264 (18): 10608-13.


Cholinoceptive properties of human primordial, preantral, and antral oocytes: in situ hybridization and biochemical evidence for expression of cholinesterase genes., Malinger G, Zakut H, Soreq H., J Mol Neurosci. January 1, 1989; 1 (2): 77-84.


Biosynthesis of catalytically active rat testosterone 5 alpha-reductase in microinjected Xenopus oocytes: evidence for tissue-specific differences in translatable mRNA., Farkash Y, Soreq H, Orly J., Proc Natl Acad Sci U S A. August 1, 1988; 85 (16): 5824-8.


Synthesis and localization of plasma proteins in the developing human brain. Integrity of the fetal blood-brain barrier to endogenous proteins of hepatic origin., Møllgård K, Dziegielewska KM, Saunders NR, Zakut H, Soreq H., Dev Biol. July 1, 1988; 128 (1): 207-21.


The use of mRNA translation in vitro and in ovo followed by crossed immunoelectrophoretic autoradiography to study the biosynthesis of human cholinesterases., Soreq H, Dziegielewska KM, Zevin-Sonkin D, Zakut H., Cell Mol Neurobiol. September 1, 1986; 6 (3): 227-37.


Synthesis of plasma proteins in fetal, adult, and neoplastic human brain tissue., Dziegielewska KM, Saunders NR, Schejter EJ, Zakut H, Zevin-Sonkin D, Zisling R, Soreq H., Dev Biol. May 1, 1986; 115 (1): 93-104.


Polymorphism of acetylcholinesterase in discrete regions of the developing human fetal brain., Zakut H, Matzkel A, Schejter E, Avni A, Soreq H., J Neurochem. August 1, 1985; 45 (2): 382-9.


A human acetylcholinesterase gene identified by homology to the Ace region of Drosophila., Soreq H, Zevin-Sonkin D, Avni A, Hall LM, Spierer P., Proc Natl Acad Sci U S A. March 1, 1985; 82 (6): 1827-31.


Expression of acetylcholinesterase gene(s) in the human brain: molecular cloning evidence for cross-homologous sequences., Zevin-Sonkin D, Avni A, Zisling R, Koch R, Soreq H., J Physiol (Paris). January 1, 1985; 80 (4): 221-8.


The biosynthesis of biologically active proteins in mRNA-microinjected Xenopus oocytes., Soreq H., CRC Crit Rev Biochem. January 1, 1985; 18 (3): 199-238.


Production of EGF-containing polypeptides in Xenopus oocytes microinjected with submaxillary gland mRNA., Burmeister M, Avivi A, Schlessinger J, Soreq H., EMBO J. July 1, 1984; 3 (7): 1499-505.


Expression of cholinesterase gene(s) in human brain tissues: translational evidence for multiple mRNA species., Soreq H, Zevin-Sonkin D, Razon N., EMBO J. June 1, 1984; 3 (6): 1371-5.


Plasminogen activator in the developing rat cerebellum: biosynthesis and localization in granular neurons., Soreq H, Miskin R., Dev Biol. December 1, 1983; 313 (2): 149-58.


Synthetic leader peptide modulates secretion of proteins from microinjected Xenopus oocytes., Koren R, Burstein Y, Soreq H., Proc Natl Acad Sci U S A. December 1, 1983; 80 (23): 7205-9.


Biosynthesis and secretion of catalytically active acetylcholinesterase in Xenopus oocytes microinjected with mRNA from rat brain and from Torpedo electric organ., Soreq H, Parvari R, Silman I., Proc Natl Acad Sci U S A. February 1, 1982; 79 (3): 830-4.


Microinjected Xenopus oocytes synthesize active human plasminogen activator., Miskin R, Soreq H., Nucleic Acids Res. July 24, 1981; 9 (14): 3355-63.


Secreted proteins in the medium of microinjected Xenopus oocytes are degraded by oocyte proteases., Soreq H, Miskin R., FEBS Lett. June 15, 1981; 128 (2): 305-10.


Translational activity and functional stability of human fibroblast beta 1 and beta 2 interferon mRNAs lacking 3'-terminal RNA sequences., Soreq H, Sagar AD, Sehgal PB., Proc Natl Acad Sci U S A. March 1, 1981; 78 (3): 1741-5.


Does 3'-terminal poly(A) stabilize human fibroblast interferon mRNA in oocytes of Xenopus laevis?, Sehgal PB, Soreq H, Tamm I., Proc Natl Acad Sci U S A. October 1, 1978; 75 (10): 5030-3.


Degradation of deadenylated rabbit alpha-globin mRNA in Xenopus oocytes is associated with its translation., Huez G, Marbaix G, Burny A, Hubert E, Leclercq M, Cleuter Y, Chantrenne H, Soreq H, Littauer UZ., Nature. March 31, 1977; 266 (5601): 473-4.


Role of the polyadenylate sequence in the stability of globin messenger RNA injected into Xenopus oocytes., Marbaix G, Huez G, Burny A, Hubert E, Leclercq M, Cleuter Y, Chantrenne H, Soreq H, Nudel U, Littauer U., Acta Biol Med Ger. January 1, 1977; 36 (3-4): 319-21.


Globin mRNA species containing poly(A) segments of different lengths. Their functional stability in Xenopus oocytes., Nudel U, Soreq H, Littauer UZ., Eur J Biochem. April 15, 1976; 64 (1): 115-21.


Readenylation of polyadenylate-free globin messenger RNA restores its stability in vivo., Huez G, Marbaix G, Hubert E, Cleuter Y, Leclercq M, Chantrenne H, Devos R, Soreq H, Nudel U, Littauer UZ., Eur J Biochem. November 15, 1975; 59 (2): 589-92.


Absence of polyadenylate segment in globin messenger RNA accelerates its degradation in Xenopus oocytes., Marbaix G, Huez G, Burny A, Cleuter Y, Hubert E, Leclercq M, Chantrenne H, Soreq H, Nudel U, Littauer UZ., Proc Natl Acad Sci U S A. August 1, 1975; 72 (8): 3065-7.

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