Jürgen Rettinger - Publications

Publications (27)

XB-PERS-2314

Publications By Jürgen Rettinger

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Validation of Alexa-647-ATP as a powerful tool to study P2X receptor ligand binding and desensitization., Bhargava Y, Nicke A, Rettinger J., Biochem Biophys Res Commun. August 23, 2013; 438 (2): 295-300.
Allosteric nature of P2X receptor activation probed by photoaffinity labelling., Bhargava Y, Rettinger J, Mourot A., Br J Pharmacol. November 1, 2012; 167 (6): 1301-10.
Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor., Lörinczi É, Bhargava Y, Marino SF, Taly A, Kaczmarek-Hájek K, Barrantes-Freer A, Dutertre S, Grutter T, Rettinger J, Nicke A., Proc Natl Acad Sci U S A. July 10, 2012; 109 (28): 11396-401.
Discovery of potent competitive antagonists and positive modulators of the P2X2 receptor., Baqi Y, Hausmann R, Rosefort C, Rettinger J, Schmalzing G, Müller CE., J Med Chem. February 10, 2011; 54 (3): 817-30.
Aminoglycoside block of P2X2 receptors heterologously expressed in Xenopus laevis oocytes., Bongartz EV, Rettinger J, Hausmann R., Purinergic Signal. December 1, 2010; 6 (4): 393-403.
A functional P2X7 splice variant with an alternative transmembrane domain 1 escapes gene inactivation in P2X7 knock-out mice., Nicke A, Kuan YH, Masin M, Rettinger J, Marquez-Klaka B, Bender O, Górecki DC, Murrell-Lagnado RD, Soto F., J Biol Chem. September 18, 2009; 284 (38): 25813-22.
Inter-subunit disulfide cross-linking in homomeric and heteromeric P2X receptors., Marquez-Klaka B, Rettinger J, Nicke A., Eur Biophys J. March 1, 2009; 38 (3): 329-38.
Agonist- and competitive antagonist-induced movement of loop 5 on the alpha subunit of the neuronal alpha4beta4 nicotinic acetylcholine receptor., Mourot A, Bamberg E, Rettinger J., J Neurochem. April 1, 2008; 105 (2): 413-24.
Identification of an intersubunit cross-link between substituted cysteine residues located in the putative ATP binding site of the P2X1 receptor., Marquez-Klaka B, Rettinger J, Bhargava Y, Eisele T, Nicke A., J Neurosci. February 7, 2007; 27 (6): 1456-66.
The suramin analog 4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic acid (NF110) potently blocks P2X3 receptors: subtype selectivity is determined by location of sulfonic acid groups., Hausmann R, Rettinger J, Gerevich Z, Meis S, Kassack MU, Illes P, Lambrecht G, Schmalzing G., Mol Pharmacol. June 1, 2006; 69 (6): 2058-67.
Profiling at recombinant homomeric and heteromeric rat P2X receptors identifies the suramin analogue NF449 as a highly potent P2X1 receptor antagonist., Rettinger J, Braun K, Hochmann H, Kassack MU, Ullmann H, Nickel P, Schmalzing G, Lambrecht G., Neuropharmacology. March 1, 2005; 48 (3): 461-8.
Assembly of nicotinic alpha7 subunits in Xenopus oocytes is partially blocked at the tetramer level., Nicke A, Thurau H, Sadtler S, Rettinger J, Schmalzing G., FEBS Lett. September 24, 2004; 575 (1-3): 52-8.
Trimeric architecture of homomeric P2X2 and heteromeric P2X1+2 receptor subtypes., Aschrafi A, Sadtler S, Niculescu C, Rettinger J, Schmalzing G., J Mol Biol. September 3, 2004; 342 (1): 333-43.
Desensitization masks nanomolar potency of ATP for the P2X1 receptor., Rettinger J, Schmalzing G., J Biol Chem. February 20, 2004; 279 (8): 6426-33.
Activation and desensitization of the recombinant P2X1 receptor at nanomolar ATP concentrations., Rettinger J, Schmalzing G., J Gen Physiol. May 1, 2003; 121 (5): 451-61.
Monomeric and dimeric byproducts are the principal functional elements of higher order P2X1 concatamers., Nicke A, Rettinger J, Schmalzing G., Mol Pharmacol. January 1, 2003; 63 (1): 243-52.
NF449: a subnanomolar potency antagonist at recombinant rat P2X1 receptors., Braun K, Rettinger J, Ganso M, Kassack M, Hildebrandt C, Ullmann H, Nickel P, Schmalzing G, Lambrecht G., Naunyn Schmiedebergs Arch Pharmacol. September 1, 2001; 364 (3): 285-90.
Roles of individual N-glycans for ATP potency and expression of the rat P2X1 receptor., Rettinger J, Aschrafi A, Schmalzing G., J Biol Chem. October 27, 2000; 275 (43): 33542-7.
The suramin analogue NF279 is a novel and potent antagonist selective for the P2X(1) receptor., Rettinger J, Schmalzing G, Damer S, Müller G, Nickel P, Lambrecht G., Neuropharmacology. August 23, 2000; 39 (11): 2044-53.
The novel pyridoxal-5'-phosphate derivative PPNDS potently antagonizes activation of P2X(1) receptors., Lambrecht G, Rettinger J, Bäumert HG, Czeche S, Damer S, Ganso M, Hildebrandt C, Niebel B, Spatz-Kümbel G, Schmalzing G, Mutschler E., Eur J Pharmacol. January 17, 2000; 387 (3): R19-21.
Novel properties of the depolarization-induced endogenous sodium conductance in the Xenopus laevis oocyte., Rettinger J., Pflugers Arch. May 1, 1999; 437 (6): 917-24.
Blue native PAGE as a useful method for the analysis of the assembly of distinct combinations of nicotinic acetylcholine receptor subunits., Nicke A, Rettinger J, Mutschler E, Schmalzing G., J Recept Signal Transduct Res. January 1, 1999; 19 (1-4): 493-507.
Voltage-dependent inhibition of the Na+,K+ pump by tetraethylammonium., Eckstein-Ludwig U, Rettinger J, Vasilets LA, Schwarz W., Biochim Biophys Acta. July 17, 1998; 1372 (2): 289-300.
P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels., Nicke A, Bäumert HG, Rettinger J, Eichele A, Lambrecht G, Mutschler E, Schmalzing G., EMBO J. June 1, 1998; 17 (11): 3016-28.
NF279: a novel potent and selective antagonist of P2X receptor-mediated responses., Damer S, Niebel B, Czeche S, Nickel P, Ardanuy U, Schmalzing G, Rettinger J, Mutschler E, Lambrecht G., Eur J Pharmacol. May 29, 1998; 350 (1): R5-6.
Characteristics of Na+/K(+)-ATPase mediated proton current in Na(+)- and K(+)-free extracellular solutions. Indications for kinetic similarities between H+/K(+)-ATPase and Na+/K(+)-ATPase., Rettinger J., Biochim Biophys Acta. July 25, 1996; 1282 (2): 207-15.
Inward-directed current generated by the Na+,K+ pump in Na(+)- and K(+)-free medium., Efthymiadis A, Rettinger J, Schwarz W., Cell Biol Int. December 1, 1993; 17 (12): 1107-16.

Validation of Alexa-647-ATP as a powerful tool to study P2X receptor ligand binding and desensitization., Bhargava Y, Nicke A, Rettinger J., Biochem Biophys Res Commun. August 23, 2013; 438 (2): 295-300.

Allosteric nature of P2X receptor activation probed by photoaffinity labelling., Bhargava Y, Rettinger J, Mourot A., Br J Pharmacol. November 1, 2012; 167 (6): 1301-10.

Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor., Lörinczi É, Bhargava Y, Marino SF, Taly A, Kaczmarek-Hájek K, Barrantes-Freer A, Dutertre S, Grutter T, Rettinger J, Nicke A., Proc Natl Acad Sci U S A. July 10, 2012; 109 (28): 11396-401.

Discovery of potent competitive antagonists and positive modulators of the P2X2 receptor., Baqi Y, Hausmann R, Rosefort C, Rettinger J, Schmalzing G, Müller CE., J Med Chem. February 10, 2011; 54 (3): 817-30.

Aminoglycoside block of P2X2 receptors heterologously expressed in Xenopus laevis oocytes., Bongartz EV, Rettinger J, Hausmann R., Purinergic Signal. December 1, 2010; 6 (4): 393-403.

A functional P2X7 splice variant with an alternative transmembrane domain 1 escapes gene inactivation in P2X7 knock-out mice., Nicke A, Kuan YH, Masin M, Rettinger J, Marquez-Klaka B, Bender O, Górecki DC, Murrell-Lagnado RD, Soto F., J Biol Chem. September 18, 2009; 284 (38): 25813-22.

Inter-subunit disulfide cross-linking in homomeric and heteromeric P2X receptors., Marquez-Klaka B, Rettinger J, Nicke A., Eur Biophys J. March 1, 2009; 38 (3): 329-38.

Agonist- and competitive antagonist-induced movement of loop 5 on the alpha subunit of the neuronal alpha4beta4 nicotinic acetylcholine receptor., Mourot A, Bamberg E, Rettinger J., J Neurochem. April 1, 2008; 105 (2): 413-24.

Identification of an intersubunit cross-link between substituted cysteine residues located in the putative ATP binding site of the P2X1 receptor., Marquez-Klaka B, Rettinger J, Bhargava Y, Eisele T, Nicke A., J Neurosci. February 7, 2007; 27 (6): 1456-66.

The suramin analog 4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic acid (NF110) potently blocks P2X3 receptors: subtype selectivity is determined by location of sulfonic acid groups., Hausmann R, Rettinger J, Gerevich Z, Meis S, Kassack MU, Illes P, Lambrecht G, Schmalzing G., Mol Pharmacol. June 1, 2006; 69 (6): 2058-67.

Profiling at recombinant homomeric and heteromeric rat P2X receptors identifies the suramin analogue NF449 as a highly potent P2X1 receptor antagonist., Rettinger J, Braun K, Hochmann H, Kassack MU, Ullmann H, Nickel P, Schmalzing G, Lambrecht G., Neuropharmacology. March 1, 2005; 48 (3): 461-8.

Assembly of nicotinic alpha7 subunits in Xenopus oocytes is partially blocked at the tetramer level., Nicke A, Thurau H, Sadtler S, Rettinger J, Schmalzing G., FEBS Lett. September 24, 2004; 575 (1-3): 52-8.

Trimeric architecture of homomeric P2X2 and heteromeric P2X1+2 receptor subtypes., Aschrafi A, Sadtler S, Niculescu C, Rettinger J, Schmalzing G., J Mol Biol. September 3, 2004; 342 (1): 333-43.

Desensitization masks nanomolar potency of ATP for the P2X1 receptor., Rettinger J, Schmalzing G., J Biol Chem. February 20, 2004; 279 (8): 6426-33.

Activation and desensitization of the recombinant P2X1 receptor at nanomolar ATP concentrations., Rettinger J, Schmalzing G., J Gen Physiol. May 1, 2003; 121 (5): 451-61.

Monomeric and dimeric byproducts are the principal functional elements of higher order P2X1 concatamers., Nicke A, Rettinger J, Schmalzing G., Mol Pharmacol. January 1, 2003; 63 (1): 243-52.

NF449: a subnanomolar potency antagonist at recombinant rat P2X1 receptors., Braun K, Rettinger J, Ganso M, Kassack M, Hildebrandt C, Ullmann H, Nickel P, Schmalzing G, Lambrecht G., Naunyn Schmiedebergs Arch Pharmacol. September 1, 2001; 364 (3): 285-90.

Roles of individual N-glycans for ATP potency and expression of the rat P2X1 receptor., Rettinger J, Aschrafi A, Schmalzing G., J Biol Chem. October 27, 2000; 275 (43): 33542-7.

The suramin analogue NF279 is a novel and potent antagonist selective for the P2X(1) receptor., Rettinger J, Schmalzing G, Damer S, Müller G, Nickel P, Lambrecht G., Neuropharmacology. August 23, 2000; 39 (11): 2044-53.

The novel pyridoxal-5'-phosphate derivative PPNDS potently antagonizes activation of P2X(1) receptors., Lambrecht G, Rettinger J, Bäumert HG, Czeche S, Damer S, Ganso M, Hildebrandt C, Niebel B, Spatz-Kümbel G, Schmalzing G, Mutschler E., Eur J Pharmacol. January 17, 2000; 387 (3): R19-21.

Novel properties of the depolarization-induced endogenous sodium conductance in the Xenopus laevis oocyte., Rettinger J., Pflugers Arch. May 1, 1999; 437 (6): 917-24.

Blue native PAGE as a useful method for the analysis of the assembly of distinct combinations of nicotinic acetylcholine receptor subunits., Nicke A, Rettinger J, Mutschler E, Schmalzing G., J Recept Signal Transduct Res. January 1, 1999; 19 (1-4): 493-507.

Voltage-dependent inhibition of the Na+,K+ pump by tetraethylammonium., Eckstein-Ludwig U, Rettinger J, Vasilets LA, Schwarz W., Biochim Biophys Acta. July 17, 1998; 1372 (2): 289-300.

P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels., Nicke A, Bäumert HG, Rettinger J, Eichele A, Lambrecht G, Mutschler E, Schmalzing G., EMBO J. June 1, 1998; 17 (11): 3016-28.

NF279: a novel potent and selective antagonist of P2X receptor-mediated responses., Damer S, Niebel B, Czeche S, Nickel P, Ardanuy U, Schmalzing G, Rettinger J, Mutschler E, Lambrecht G., Eur J Pharmacol. May 29, 1998; 350 (1): R5-6.

Characteristics of Na+/K(+)-ATPase mediated proton current in Na(+)- and K(+)-free extracellular solutions. Indications for kinetic similarities between H+/K(+)-ATPase and Na+/K(+)-ATPase., Rettinger J., Biochim Biophys Acta. July 25, 1996; 1282 (2): 207-15.

Inward-directed current generated by the Na+,K+ pump in Na(+)- and K(+)-free medium., Efthymiadis A, Rettinger J, Schwarz W., Cell Biol Int. December 1, 1993; 17 (12): 1107-16.

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