Chenghao Tang - Publications

Publications (19)

XB-PERS-1532

Publications By Chenghao Tang

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Design of Xenopus GLP-1-Based Long-Acting Dual GLP-1/Y2 Receptor Agonists., Yang Q, Tang W, Sun L, Yan Z, Tang C, Yuan Y, Zhou H, Zhou F, Zhou S, Wu Q, Song P, Fang T, Xu R, Han J, Jiang N., J Med Chem. October 27, 2022; 65 (20): 14201-14220.
A GLP-1/glucagon (GCG)/CCK2 receptors tri-agonist provides new therapy for obesity and diabetes., Zhao S, Yan Z, Du Y, Li Z, Tang C, Jing L, Sun L, Yang Q, Tang X, Yuan Y, Han J, Jiang N., Br J Pharmacol. September 1, 2022; 179 (17): 4360-4377.
Novel KCND3 Variant Underlying Nonprogressive Congenital Ataxia or SCA19/22 Disrupt KV4.3 Protein Expression and K+ Currents with Variable Effects on Channel Properties., Zanni G, Hsiao CT, Fu SJ, Tang CY, Capuano A, Bosco L, Graziola F, Bellacchio E, Servidei S, Primiano G, Soong BW, Jeng CJ., Int J Mol Sci. May 7, 2021; 22 (9):
PbrSLAH3 is a nitrate-selective anion channel which is modulated by calcium-dependent protein kinase 32 in pear., Chen G, Wang L, Chen Q, Qi K, Yin H, Cao P, Tang C, Wu X, Zhang S, Wang P, Wu J., BMC Plant Biol. May 8, 2019; 19 (1): 190.
Ubiquitin Ligase RNF138 Promotes Episodic Ataxia Type 2-Associated Aberrant Degradation of Human Cav2.1 (P/Q-Type) Calcium Channels., Fu SJ, Jeng CJ, Ma CH, Peng YJ, Lee CM, Fang YC, Lee YC, Tang SC, Hu MC, Tang CY., J Neurosci. March 1, 2017; 37 (9): 2485-2503.
Concentration-response relationship of the α7 nicotinic acetylcholine receptor agonist FRM-17874 across multiple in vitro and in vivo assays., Stoiljkovic M, Leventhal L, Chen A, Chen T, Driscoll R, Flood D, Hodgdon H, Hurst R, Nagy D, Piser T, Tang C, Townsend M, Tu Z, Bertrand D, Koenig G, Hajós M., Biochem Pharmacol. October 15, 2015; 97 (4): 576-89.
PKC and AMPK regulation of Kv1.5 potassium channels., Andersen MN, Skibsbye L, Tang C, Petersen F, MacAulay N, Rasmussen HB, Jespersen T., Channels (Austin). January 1, 2015; 9 (3): 121-8.
Dominantly inherited myotonia congenita resulting from a mutation that increases open probability of the muscle chloride channel CLC-1., Richman DP, Yu Y, Lee TT, Tseng PY, Yu WP, Maselli RA, Tang CY, Chen TY., Neuromolecular Med. December 1, 2012; 14 (4): 328-37.
PIP5K2A-dependent regulation of excitatory amino acid transporter EAAT3., Fedorenko O, Tang C, Sopjani M, Föller M, Gehring EM, Strutz-Seebohm N, Ureche ON, Ivanova S, Semke A, Lang F, Seebohm G, Lang UE., Psychopharmacology (Berl). October 1, 2009; 206 (3): 429-35.
Effects of sodium azide, barium ion, d-amphetamine and procaine on inward rectifying potassium channel 6.2 expressed in Xenopus oocytes., Kung FL, Tsai JL, Lee CH, Lou KL, Tang CY, Liou HH, Lu KL, Chen YH, Wang WJ, Tsai MC., J Formos Med Assoc. August 1, 2008; 107 (8): 600-8.
Robust, tunable biological oscillations from interlinked positive and negative feedback loops., Tsai TY, Choi YS, Ma W, Pomerening JR, Tang C, Ferrell JE., Science. July 4, 2008; 321 (5885): 126-9.
Dominant-negative effects of episodic ataxia type 2 mutations involve disruption of membrane trafficking of human P/Q-type Ca2+ channels., Jeng CJ, Sun MC, Chen YW, Tang CY., J Cell Physiol. February 1, 2008; 214 (2): 422-33.
Dominant-negative effects of human P/Q-type Ca2+ channel mutations associated with episodic ataxia type 2., Jeng CJ, Chen YT, Chen YW, Tang CY., Am J Physiol Cell Physiol. April 1, 2006; 290 (4): C1209-20.
Beauvericin activates Ca2+-activated Cl- currents and induces cell deaths in Xenopus oocytes via influx of extracellular Ca2+., Tang CY, Chen YW, Jow GM, Chou CJ, Jeng CJ., Chem Res Toxicol. May 1, 2005; 18 (5): 825-33.
Mg(2+) modulates voltage-dependent activation in ether-à-go-go potassium channels by binding between transmembrane segments S2 and S3., Silverman WR, Tang CY, Mock AF, Huh KB, Papazian DM., J Gen Physiol. November 1, 2000; 116 (5): 663-78.
Extracellular Mg(2+) modulates slow gating transitions and the opening of Drosophila ether-à-Go-Go potassium channels., Tang CY, Bezanilla F, Papazian DM., J Gen Physiol. March 1, 2000; 115 (3): 319-38.
GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2., Jones KA, Borowsky B, Tamm JA, Craig DA, Durkin MM, Dai M, Yao WJ, Johnson M, Gunwaldsen C, Huang LY, Tang C, Shen Q, Salon JA, Morse K, Laz T, Smith KE, Nagarathnam D, Noble SA, Branchek TA, Gerald C., Nature. December 17, 1998; 396 (6712): 674-9.
Shaker and ether-à-go-go K+ channel subunits fail to coassemble in Xenopus oocytes., Tang CY, Schulteis CT, Jiménez RM, Papazian DM., Biophys J. September 1, 1998; 75 (3): 1263-70.
Conserved cysteine residues in the shaker K+ channel are not linked by a disulfide bond., Schulteis CT, John SA, Huang Y, Tang CY, Papazian DM., Biochemistry. February 7, 1995; 34 (5): 1725-33.

Design of Xenopus GLP-1-Based Long-Acting Dual GLP-1/Y2 Receptor Agonists., Yang Q, Tang W, Sun L, Yan Z, Tang C, Yuan Y, Zhou H, Zhou F, Zhou S, Wu Q, Song P, Fang T, Xu R, Han J, Jiang N., J Med Chem. October 27, 2022; 65 (20): 14201-14220.

A GLP-1/glucagon (GCG)/CCK2 receptors tri-agonist provides new therapy for obesity and diabetes., Zhao S, Yan Z, Du Y, Li Z, Tang C, Jing L, Sun L, Yang Q, Tang X, Yuan Y, Han J, Jiang N., Br J Pharmacol. September 1, 2022; 179 (17): 4360-4377.

Novel KCND3 Variant Underlying Nonprogressive Congenital Ataxia or SCA19/22 Disrupt KV4.3 Protein Expression and K+ Currents with Variable Effects on Channel Properties., Zanni G, Hsiao CT, Fu SJ, Tang CY, Capuano A, Bosco L, Graziola F, Bellacchio E, Servidei S, Primiano G, Soong BW, Jeng CJ., Int J Mol Sci. May 7, 2021; 22 (9):

PbrSLAH3 is a nitrate-selective anion channel which is modulated by calcium-dependent protein kinase 32 in pear., Chen G, Wang L, Chen Q, Qi K, Yin H, Cao P, Tang C, Wu X, Zhang S, Wang P, Wu J., BMC Plant Biol. May 8, 2019; 19 (1): 190.

Ubiquitin Ligase RNF138 Promotes Episodic Ataxia Type 2-Associated Aberrant Degradation of Human Cav2.1 (P/Q-Type) Calcium Channels., Fu SJ, Jeng CJ, Ma CH, Peng YJ, Lee CM, Fang YC, Lee YC, Tang SC, Hu MC, Tang CY., J Neurosci. March 1, 2017; 37 (9): 2485-2503.

Concentration-response relationship of the α7 nicotinic acetylcholine receptor agonist FRM-17874 across multiple in vitro and in vivo assays., Stoiljkovic M, Leventhal L, Chen A, Chen T, Driscoll R, Flood D, Hodgdon H, Hurst R, Nagy D, Piser T, Tang C, Townsend M, Tu Z, Bertrand D, Koenig G, Hajós M., Biochem Pharmacol. October 15, 2015; 97 (4): 576-89.

PKC and AMPK regulation of Kv1.5 potassium channels., Andersen MN, Skibsbye L, Tang C, Petersen F, MacAulay N, Rasmussen HB, Jespersen T., Channels (Austin). January 1, 2015; 9 (3): 121-8.

Dominantly inherited myotonia congenita resulting from a mutation that increases open probability of the muscle chloride channel CLC-1., Richman DP, Yu Y, Lee TT, Tseng PY, Yu WP, Maselli RA, Tang CY, Chen TY., Neuromolecular Med. December 1, 2012; 14 (4): 328-37.

PIP5K2A-dependent regulation of excitatory amino acid transporter EAAT3., Fedorenko O, Tang C, Sopjani M, Föller M, Gehring EM, Strutz-Seebohm N, Ureche ON, Ivanova S, Semke A, Lang F, Seebohm G, Lang UE., Psychopharmacology (Berl). October 1, 2009; 206 (3): 429-35.

Effects of sodium azide, barium ion, d-amphetamine and procaine on inward rectifying potassium channel 6.2 expressed in Xenopus oocytes., Kung FL, Tsai JL, Lee CH, Lou KL, Tang CY, Liou HH, Lu KL, Chen YH, Wang WJ, Tsai MC., J Formos Med Assoc. August 1, 2008; 107 (8): 600-8.

Robust, tunable biological oscillations from interlinked positive and negative feedback loops., Tsai TY, Choi YS, Ma W, Pomerening JR, Tang C, Ferrell JE., Science. July 4, 2008; 321 (5885): 126-9.

Dominant-negative effects of episodic ataxia type 2 mutations involve disruption of membrane trafficking of human P/Q-type Ca2+ channels., Jeng CJ, Sun MC, Chen YW, Tang CY., J Cell Physiol. February 1, 2008; 214 (2): 422-33.

Dominant-negative effects of human P/Q-type Ca2+ channel mutations associated with episodic ataxia type 2., Jeng CJ, Chen YT, Chen YW, Tang CY., Am J Physiol Cell Physiol. April 1, 2006; 290 (4): C1209-20.

Beauvericin activates Ca2+-activated Cl- currents and induces cell deaths in Xenopus oocytes via influx of extracellular Ca2+., Tang CY, Chen YW, Jow GM, Chou CJ, Jeng CJ., Chem Res Toxicol. May 1, 2005; 18 (5): 825-33.

Mg(2+) modulates voltage-dependent activation in ether-à-go-go potassium channels by binding between transmembrane segments S2 and S3., Silverman WR, Tang CY, Mock AF, Huh KB, Papazian DM., J Gen Physiol. November 1, 2000; 116 (5): 663-78.

Extracellular Mg(2+) modulates slow gating transitions and the opening of Drosophila ether-à-Go-Go potassium channels., Tang CY, Bezanilla F, Papazian DM., J Gen Physiol. March 1, 2000; 115 (3): 319-38.

GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2., Jones KA, Borowsky B, Tamm JA, Craig DA, Durkin MM, Dai M, Yao WJ, Johnson M, Gunwaldsen C, Huang LY, Tang C, Shen Q, Salon JA, Morse K, Laz T, Smith KE, Nagarathnam D, Noble SA, Branchek TA, Gerald C., Nature. December 17, 1998; 396 (6712): 674-9.

Shaker and ether-à-go-go K+ channel subunits fail to coassemble in Xenopus oocytes., Tang CY, Schulteis CT, Jiménez RM, Papazian DM., Biophys J. September 1, 1998; 75 (3): 1263-70.

Conserved cysteine residues in the shaker K+ channel are not linked by a disulfide bond., Schulteis CT, John SA, Huang Y, Tang CY, Papazian DM., Biochemistry. February 7, 1995; 34 (5): 1725-33.

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