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Profile Publications (101)
XB-PERS-740

Publications By Christof Niehrs

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Transcriptional regulation of BMP4 synexpression in transgenic Xenopus., Karaulanov E, Knöchel W, Niehrs C., EMBO J. February 25, 2004; 23 (4): 844-56.


Reliability of gene expression ratios for cDNA microarrays in multiconditional experiments with a reference design., König R, Baldessari D, Pollet N, Niehrs C, Eils R., Nucleic Acids Res. February 13, 2004; 32 (3): e29.


The transmembrane protein XFLRT3 forms a complex with FGF receptors and promotes FGF signalling., Böttcher RT, Pollet N, Delius H, Niehrs C., Nat Cell Biol. January 1, 2004; 6 (1): 38-44.    


Dkk1 and noggin cooperate in mammalian head induction., del Barco Barrantes I, Davidson G, Gröne HJ, Westphal H, Niehrs C., Genes Dev. September 15, 2003; 17 (18): 2239-44.


Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling., Mao B, Niehrs C., Gene. January 2, 2003; 302 (1-2): 179-83.        


In situ analysis of gene expression in Xenopus embryos., Pollet N, Delius H, Niehrs C., C R Biol. January 1, 2003; 326 (10-11): 1011-7.


Cyclic expression of esr9 gene in Xenopus presomitic mesoderm., Li Y, Fenger U, Niehrs C, Pollet N., Differentiation. January 1, 2003; 71 (1): 83-9.          


Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning., Davidson G, Mao B, del Barco Barrantes I, Niehrs C., Development. December 1, 2002; 129 (24): 5587-96.        


A morphogen gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus., Kiecker C, Niehrs C., Development. November 1, 2001; 128 (21): 4189-201.              


Developmental biology. Solving a sticky problem., Niehrs C., Nature. October 25, 2001; 413 (6858): 787-8.


Cloning and characterization of Plx2 and Plx3, two additional Polo-like kinases from Xenopus laevis., Duncan PI, Pollet N, Niehrs C, Nigg EA., Exp Cell Res. October 15, 2001; 270 (1): 78-87.


Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse., Mukhopadhyay M, Shtrom S, Rodriguez-Esteban C, Chen L, Tsukui T, Gomer L, Dorward DW, Glinka A, Grinberg A, Huang SP, Niehrs C, Izpisúa Belmonte JC, Westphal H., Dev Cell. September 1, 2001; 1 (3): 423-34.


Nrarp is a novel intracellular component of the Notch signaling pathway., Lamar E, Deblandre G, Wettstein D, Gawantka V, Pollet N, Niehrs C, Kintner C., Genes Dev. August 1, 2001; 15 (15): 1885-99.                        


LDL-receptor-related protein 6 is a receptor for Dickkopf proteins., Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C., Nature. May 17, 2001; 411 (6835): 321-5.


Increased XRALDH2 activity has a posteriorizing effect on the central nervous system of Xenopus embryos., Chen Y, Pollet N, Niehrs C, Pieler T., Mech Dev. March 1, 2001; 101 (1-2): 91-103.        


Dickkopf1 and the Spemann-Mangold head organizer., Niehrs C, Kazanskaya O, Wu W, Glinka A., Int J Dev Biol. January 1, 2001; 45 (1): 237-40.    


Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling., Wu W, Glinka A, Delius H, Niehrs C., Curr Biol. December 1, 2000; 10 (24): 1611-4.        


The role of Xenopus dickkopf1 in prechordal plate specification and neural patterning., Kazanskaya O, Glinka A, Niehrs C., Development. November 1, 2000; 127 (22): 4981-92.              


Dissecting GHRH- and pituitary adenylate cyclase activating polypeptide-mediated signalling in Xenopus., Otto C, Schütz G, Niehrs C, Glinka A., Mech Dev. June 1, 2000; 94 (1-2): 111-6.        


Phenotypic effects in Xenopus and zebrafish suggest that one-eyed pinhead functions as antagonist of BMP signalling., Kiecker C, Müller F, Wu W, Glinka A, Strähle U, Niehrs C., Mech Dev. June 1, 2000; 94 (1-2): 37-46.          


Anterior endoderm and head induction in early vertebrate embryos., de Souza FS, Niehrs C., Cell Tissue Res. May 1, 2000; 300 (2): 207-17.


Requirement for anti-dorsalizing morphogenetic protein in organizer patterning., Dosch R, Niehrs C., Mech Dev. February 1, 2000; 90 (2): 195-203.


The genomic structure, chromosome location, and analysis of the human DKK1 head inducer gene as a candidate for holoprosencephaly., Roessler E, Du Y, Glinka A, Dutra A, Niehrs C, Muenke M., Cytogenet Cell Genet. January 1, 2000; 89 (3-4): 220-4.


Amphibian organizer activity., Niehrs C., Methods Mol Biol. January 1, 2000; 137 179-83.


Embryonic patterning of Xenopus mesoderm by Bmp-4., Niehrs C, Dosch R, Onichtchouk D., Ernst Schering Res Found Workshop. January 1, 2000; (29): 165-90.


In silico analysis of gene expression patterns during early development of Xenopus laevis., Pollet N, Schmidt HA, Gawantka V, Niehrs C, Vingron M., Pac Symp Biocomput. January 1, 2000; 443-54.


Axeldb: a Xenopus laevis database focusing on gene expression., Pollet N, Schmidt HA, Gawantka V, Vingron M, Niehrs C., Nucleic Acids Res. January 1, 2000; 28 (1): 139-40.


Synexpression groups in eukaryotes., Niehrs C, Pollet N., Nature. December 2, 1999; 402 (6761): 483-7.


The zinc finger gene Xblimp1 controls anterior endomesodermal cell fate in Spemann's organizer., de Souza FS, Gawantka V, Gómez AP, Delius H, Ang SL, Niehrs C., EMBO J. November 1, 1999; 18 (21): 6062-72.


Essential role of CREB family proteins during Xenopus embryogenesis., Lutz B, Schmid W, Niehrs C, Schütz G., Mech Dev. October 1, 1999; 88 (1): 55-66.          


Silencing of TGF-beta signalling by the pseudoreceptor BAMBI., Onichtchouk D, Chen YG, Dosch R, Gawantka V, Delius H, Massagué J, Niehrs C., Nature. September 30, 1999; 401 (6752): 480-5.


Dickkopf genes are co-ordinately expressed in mesodermal lineages., Monaghan AP, Kioschis P, Wu W, Zuniga A, Bock D, Poustka A, Delius H, Niehrs C., Mech Dev. September 1, 1999; 87 (1-2): 45-56.      


RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase., Askjaer P, Bachi A, Wilm M, Bischoff FR, Weeks DL, Ogniewski V, Ohno M, Niehrs C, Kjems J, Mattaj IW, Fornerod M., Mol Cell Biol. September 1, 1999; 19 (9): 6276-85.


Periodic repression of Notch pathway genes governs the segmentation of Xenopus embryos., Jen WC, Gawantka V, Pollet N, Niehrs C, Kintner C., Genes Dev. June 1, 1999; 13 (11): 1486-99.                  


Gene expression screening in Xenopus identifies molecular pathways, predicts gene function and provides a global view of embryonic patterning., Gawantka V, Pollet N, Delius H, Vingron M, Pfister R, Nitsch R, Blumenstock C, Niehrs C., Mech Dev. October 1, 1998; 77 (2): 95-141.                                                            


Patterns and control of cell motility in the Xenopus gastrula., Wacker S, Brodbeck A, Lemaire P, Niehrs C, Winklbauer R., Development. May 1, 1998; 125 (10): 1931-42.


Requirement for Xvent-1 and Xvent-2 gene function in dorsoventral patterning of Xenopus mesoderm., Onichtchouk D, Glinka A, Niehrs C., Development. April 1, 1998; 125 (8): 1447-56.                  


Antimorphic goosecoids., Ferreiro B, Artinger M, Cho K, Niehrs C., Development. April 1, 1998; 125 (8): 1347-59.


Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction., Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C., Nature. January 22, 1998; 391 (6665): 357-62.


Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads., Candia AF, Watabe T, Hawley SH, Onichtchouk D, Zhang Y, Derynck R, Niehrs C, Cho KW., Development. November 1, 1997; 124 (22): 4467-80.


Head induction by simultaneous repression of Bmp and Wnt signalling in Xenopus., Glinka A, Wu W, Onichtchouk D, Blumenstock C, Niehrs C., Nature. October 2, 1997; 389 (6650): 517-9.


Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus., Dosch R, Gawantka V, Delius H, Blumenstock C, Niehrs C., Development. June 1, 1997; 124 (12): 2325-34.          


The C-terminal domain of Mad-like signal transducers is sufficient for biological activity in the Xenopus embryo and transcriptional activation., Meersseman G, Verschueren K, Nelles L, Blumenstock C, Kraft H, Wuytens G, Remacle J, Kozak CA, Tylzanowski P, Niehrs C, Huylebroeck D., Mech Dev. January 1, 1997; 61 (1-2): 127-40.    


Combinatorial signalling by Xwnt-11 and Xnr3 in the organizer epithelium., Glinka A, Delius H, Blumenstock C, Niehrs C., Mech Dev. December 1, 1996; 60 (2): 221-31.          


The Xvent-2 homeobox gene is part of the BMP-4 signalling pathway controlling [correction of controling] dorsoventral patterning of Xenopus mesoderm., Onichtchouk D, Gawantka V, Dosch R, Delius H, Hirschfeld K, Blumenstock C, Niehrs C., Development. October 1, 1996; 122 (10): 3045-53.                  


Antagonizing the Spemann organizer: role of the homeobox gene Xvent-1., Gawantka V, Delius H, Hirschfeld K, Blumenstock C, Niehrs C., EMBO J. December 15, 1995; 14 (24): 6268-79.


The role of gsc and BMP-4 in dorsal-ventral patterning of the marginal zone in Xenopus: a loss-of-function study using antisense RNA., Steinbeisser H, Fainsod A, Niehrs C, Sasai Y, De Robertis EM., EMBO J. November 1, 1995; 14 (21): 5230-43.


Mesodermal patterning by a gradient of the vertebrate homeobox gene goosecoid., Niehrs C, Steinbeisser H, De Robertis EM., Science. February 11, 1994; 263 (5148): 817-20.


The homeobox gene goosecoid controls cell migration in Xenopus embryos., Niehrs C, Keller R, Cho KW, De Robertis EM., Cell. February 26, 1993; 72 (4): 491-503.              


Goosecoid and the organizer., De Roberts EM, Blum M, Niehrs C, Steinbeisser H., Dev Suppl. January 1, 1992; 167-71.

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