Research InterestsEpigentic Memory, Reprogramming and Cell Fate
Research AreaWe combine somatic cell nuclear transfer to Xenopus eggs with innovative multi-omics to study how a cell can remember its identity in order to erase its memory. In mammals, epigenetic reprogramming, the acquisition and loss of totipotency, and the first cell fate decision all occur within a three-day window after fertilization of the oocyte by the sperm. Molecularly, these processes are poorly understood, yet this knowledge is an essential prerequisite to uncover principles of stem cells, chromatin biology, and thus regenerative medicine.
Current MembersHörmanseder, Eva B (Principal Investigator/Director)
Additional InformationOur Research Topics: - Epigenetic Memory - Reprogramming to Totipotency - Barriers to Cell Fate Changes Visit our website for more information!
ContactInstitution: Helmholtz Munich Address:
IEB:Institute of Epigenetics and Stem Cells