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Summary Anatomy Item Literature (97) Expression Attributions Wiki

Anatomy Term: primordial germ cell
XAO ID: 0003149
Synonyms: PGC, primitive germ cell
Definition: "Cell that arises from the endodermal germ plasm and can be detected by NF stage 28 in the endodermal mass. At NF stages 42-47, PGCs migrate to the two genital ridges, which are the first rudiments of the gonads. By NF stage 50, the PGCs begin to loose their yolky material. In males, starting at NF stage 52, PGCs migrate from the genital ridge cortical region into the medullary tissue, where they will form primary spermatogonia at sexual maturity. In females, the medullary tissue remains free of PGCs; they instead embed in the cortical region and multiply to form primary oogonia, which will mature into ova at sexual maturity."
Stage Range: NF stage 28 to NF stage 58
Marker Genes: pgat grip2
Antibody: Nanos1 Ab1 Pgat Ab1
Develops From:
Anatomy Item Stage Range
endoderm NF stage 10 to NF stage 66
germ plasm oocyte stage I to NF stage 40
Develops Into:
Anatomy Item Stage Range
primary oogonium NF stage 54 to death
primary spermatogonium NF stage 59 to death
Parent(s): endoderm, germ plasm


Parent(s): germ cell (is_a) obsolete germ line cell (is_a)


References: Ontology Lookup Service , XB ANATOMY ONTOLOGY