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Summary Anatomy Item Literature (1239) Expression Attributions Wiki

Anatomy Term: neural crest
XAO ID: 0000048
Synonyms: neural crest material, NC
Definition: "A group of ectoderm cells that delaminate from the area between the neuroectoderm/non-neural ectoderm domains. They undergo epithelial-to-mesenchymal tranformation (EMT) and migrate to give several different lineages of adult cells. Originating from different positions along the anterior-posterior axis, they develop into various tissues. These regions of neural crest can be divided into five main functional domains, which include the cranial, trunk, vagal and sacral neural crest, and cardiac neural crest. Neural crest cells are considered multipotent, and as they have the limited capacity for self renewal, they are regarded as stem cell-like."
Stage Range: NF stage 13 to NF stage 44
Marker Genes: sox9 dlx2
Develops From:
Anatomy Item Stage Range
chordal neural plate border NF stage 13 to NF stage 22
ectoderm NF stage 10 to NF stage 66
neural plate border NF stage 11.5 to NF stage 22
sensorial layer of neurectoderm NF stage 11.5 to NF stage 66
Develops Into:
Anatomy Item Stage Range
afferent neuron NF stage 15 to death
branchial crest NF stage 15 to NF stage 44
efferent neuron NF stage 15 to death
enteric nervous system NF stage 15 to death
enteric neuron NF stage 20 to death
glial cell NF stage 22 to death
melanoblast NF stage 26 to NF stage 32
migratory neural crest cell NF stage 13 to NF stage 32
peripheral ganglion NF stage 28 to death
Parent(s): chordal neural plate border, ectoderm, neural plate border, sensorial layer of neurectoderm


Parent(s): tissue (is_a) neuroectoderm (part_of)


References: Ontology Lookup Service , XB ANATOMY ONTOLOGY