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Xenopus: Experimental Access to Cardiovascular Development, Regeneration Discovery, and Cardiovascular Heart-Defect Modeling. , Hoppler S ., Cold Spring Harb Perspect Biol. June 1, 2020; 12 (6):
Effect of salinity acclimation on osmoregulation, oxidative stress, and metabolic enzymes in the invasive Xenopus laevis. , Hidalgo J., J Exp Zool A Ecol Integr Physiol. June 1, 2020; 333 (5): 333-340.
Swimming toward solutions: Using fish and frogs as models for understanding RASopathies. , Patterson VL., Birth Defects Res. June 1, 2020; 112 (10): 749-765.
A lower X-gate in TASK channels traps inhibitors within the vestibule. , Rödström KEJ., Nature. June 1, 2020; 582 (7812): 443-447.
Pharmacologic TWIK-Related Acid-Sensitive K+ Channel (TASK-1) Potassium Channel Inhibitor A293 Facilitates Acute Cardioversion of Paroxysmal Atrial Fibrillation in a Porcine Large Animal Model. , Wiedmann F., J Am Heart Assoc. May 18, 2020; 9 (10): e015751.
Smooth Muscle in Cardiac Chambers is Common in Turtles and Extensive in the Emydid Turtle, Trachemys scripta. , Joyce W., Anat Rec (Hoboken). May 1, 2020; 303 (5): 1327-1336.
Multidirectional Changes in Parameters related to Sulfur Metabolism in Frog Tissues exposed to Heavy Metal-related Stress. , Kaczor-Kamińska M., Biomolecules. April 9, 2020; 10 (4):
4,4'-Diisothiocyanato-2,2'-Stilbenedisulfonic Acid (DIDS) Modulates the Activity of KCNQ1/KCNE1 Channels by an Interaction with the Central Pore Region. , Bollmann E., Cell Physiol Biochem. April 8, 2020; 54 (2): 321-332.
A Collision Coupling Model Governs the Activation of Neuronal GIRK1/2 Channels by Muscarinic-2 Receptors. , Berlin S., Front Pharmacol. April 7, 2020; 11 1216.
Chloroform is a potent activator of cardiac and neuronal Kir3 channels. , Kollert S., Naunyn Schmiedebergs Arch Pharmacol. April 1, 2020; 393 (4): 573-580.
Polyunsaturated fatty acid analogues differentially affect cardiac NaV, CaV, and KV channels through unique mechanisms. , Bohannon BM., Elife. March 24, 2020; 9
Model systems for regeneration: Xenopus. , Phipps LS., Development. March 19, 2020; 147 (6):
The secreted BMP antagonist ERFE is required for the development of a functional circulatory system in Xenopus. , Melchert J., Dev Biol. March 15, 2020; 459 (2): 138-148.
Characterization of a novel thyrotropin-releasing hormone receptor, TRHR3, in chickens. , Li X., Poult Sci. March 1, 2020; 99 (3): 1643-1654.
Stabilization of Gaze during Early Xenopus Development by Swimming-Related Utricular Signals. , Lambert FM ., Curr Biol. February 24, 2020; 30 (4): 746-753.e4.
Dynamic clamp constructed phase diagram for the Hodgkin and Huxley model of excitability. , Ori H., Proc Natl Acad Sci U S A. February 18, 2020; 117 (7): 3575-3582.
Disrupted ER membrane protein complex-mediated topogenesis drives congenital neural crest defects. , Marquez J ., J Clin Invest. February 3, 2020; 130 (2): 813-826.
Cardiac telocytes exist in the adult Xenopus tropicalis heart. , Lv L., J Cell Mol Med. February 1, 2020; 24 (4): 2531-2541.
A scalable pipeline for designing reconfigurable organisms. , Kriegman S., Proc Natl Acad Sci U S A. January 28, 2020; 117 (4): 1853-1859.
Shear force sensing of epithelial Na+ channel (ENaC) relies on N-glycosylated asparagines in the palm and knuckle domains of αENaC. , Knoepp F., Proc Natl Acad Sci U S A. January 7, 2020; 117 (1): 717-726.
Differential expression of foxo genes during embryonic development and in adult tissues of Xenopus tropicalis. , Zheng L., Gene Expr Patterns. January 1, 2020; 35 119091.
The roles and controls of GATA factors in blood and cardiac development. , Dobrzycki T., IUBMB Life. January 1, 2020; 72 (1): 39-44.
Dehydration stress alters the mitogen-activated-protein kinase signaling and chaperone stress response in Xenopus laevis. , Wu CW ., Comp Biochem Physiol B Biochem Mol Biol. January 1, 2020; 246-247 110461.
HCN2 Channel-Induced Rescue of Brain Teratogenesis via Local and Long-Range Bioelectric Repair. , Pai VP ., Front Cell Neurosci. January 1, 2020; 14 136.
Lampreys, the jawless vertebrates, contain three Pax6 genes with distinct expression in eye, brain and pancreas. , Ravi V., Sci Rep. December 20, 2019; 9 (1): 19559.
S-nitrosylation of connexin43 hemichannels elicits cardiac stress-induced arrhythmias in Duchenne muscular dystrophy mice. , Lillo MA., JCI Insight. December 19, 2019; 4 (24):
Expression of the guanine nucleotide exchange factor, RAPGEF5, during mouse and human embryogenesis. , Alharatani R., Gene Expr Patterns. December 1, 2019; 34 119057.
DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract. , Blackburn ATM., Genet Med. December 1, 2019; 21 (12): 2755-2764.
Allocation trade-offs impact organ size and muscle architecture in an invasive population of Xenopus laevis in Western France. , Padilla P., J Anat. December 1, 2019; 235 (6): 1057-1064.
Alkylglycerol monooxygenase, a heterotaxy candidate gene, regulates left- right patterning via Wnt signaling. , Duncan AR., Dev Biol. December 1, 2019; 456 (1): 1-7.
Comparative Analysis of the Developmental Toxicity in Xenopus laevis and Danio rerio Induced by Al2 O3 Nanoparticle Exposure. , Ismail T., Environ Toxicol Chem. December 1, 2019; 38 (12): 2672-2681.
Investigating the utility of adult zebrafish ex vivo whole hearts to pharmacologically screen hERG channel activator compounds. , Hull CM., Am J Physiol Regul Integr Comp Physiol. December 1, 2019; 317 (6): R921-R931.
Effects of antidepressants with different modes of action on early life stages of fish and amphibians. , Sehonova P., Environ Pollut. November 1, 2019; 254 (Pt A): 112999.
Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish. , Burczyk MS., JCI Insight. October 17, 2019; 4 (20):
Conservation and divergence of protein pathways in the vertebrate heart. , Federspiel JD., PLoS Biol. September 6, 2019; 17 (9): e3000437.
Non-sedating antihistamines block G-protein-gated inwardly rectifying K+ channels. , Chen IS., Br J Pharmacol. September 1, 2019; 176 (17): 3161-3179.
The acute effects of hydrocortisone on cardiac electrocardiography, action potentials, intracellular calcium, and contraction: The role of protein kinase C. , Park MH., Mol Cell Endocrinol. August 20, 2019; 494 110488.
Noncanonical mechanism of voltage sensor coupling to pore revealed by tandem dimers of Shaker. , Carvalho-de-Souza JL., Nat Commun. August 8, 2019; 10 (1): 3584.
Cardiotoxicity in African clawed frog (Xenopus laevis) sub-chronically exposed to environmentally relevant atrazine concentrations: Implications for species survival. , Asouzu Johnson J., Aquat Toxicol. August 1, 2019; 213 105218.
ML277 specifically enhances the fully activated open state of KCNQ1 by modulating VSD-pore coupling. , Hou P., Elife. July 22, 2019; 8
Histone H2B monoubiquitination regulates heart development via epigenetic control of cilia motility. , Robson A., Proc Natl Acad Sci U S A. July 9, 2019; 116 (28): 14049-14054.
Antiarrhythmic Properties of Ranolazine: Inhibition of Atrial Fibrillation Associated TASK-1 Potassium Channels. , Ratte A., Front Pharmacol. July 3, 2019; 10 1367.
Cardiac K2P13.1 (THIK-1) two-pore-domain K+ channels: Pharmacological regulation and remodeling in atrial fibrillation. , Staudacher I., Prog Biophys Mol Biol. July 1, 2019; 144 128-138.
Importance of the Choice of a Recombinant System to Produce Large Amounts of Functional Membrane Protein hERG. , Vasseur L., Int J Mol Sci. June 28, 2019; 20 (13):
Desmoplakin is required for epidermal integrity and morphogenesis in the Xenopus laevis embryo. , Bharathan NK., Dev Biol. June 15, 2019; 450 (2): 115-131.
N-glycosylation-dependent regulation of hK2P17.1 currents. , Wiedmann F., Mol Biol Cell. June 1, 2019; 30 (12): 1425-1436.
Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis. , Schwenty-Lara J., Dev Dyn. June 1, 2019; 248 (6): 465-476.
Genes and mechanisms of heterotaxy: patients drive the search. , Sempou E., Curr Opin Genet Dev. June 1, 2019; 56 34-40.
A deficiency in SUMOylation activity disrupts multiple pathways leading to neural tube and heart defects in Xenopus embryos. , Bertke MM., BMC Genomics. May 17, 2019; 20 (1): 386.
Optical Control of Cardiac Function with a Photoswitchable Muscarinic Agonist. , Riefolo F., J Am Chem Soc. May 8, 2019; 141 (18): 7628-7636.