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In vitro inhibition of human nucleoside transporters and uptake of azacitidine by an isocitrate dehydrogenase-2 inhibitor enasidenib and its metabolite AGI-16903. , Tong Z., Xenobiotica. October 1, 2019; 49 (10): 1229-1236.
Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex. , Qu Y., Elife. November 13, 2019; 8
The histone methyltransferase KMT2D, mutated in Kabuki syndrome patients, is required for neural crest cell formation and migration. , Schwenty-Lara J., Hum Mol Genet. January 15, 2020; 29 (2): 305-319.
Six1 proteins with human branchio-oto-renal mutations differentially affect cranial gene expression and otic development. , Shah AM., Dis Model Mech. March 3, 2020; 13 (3):
Characterization of AN6001, a positive allosteric modulator of α6β2-containing nicotinic acetylcholine receptors. , van Hout M., Biochem Pharmacol. April 1, 2020; 174 113788.
Dynamic expression of MMP28 during cranial morphogenesis. , Gouignard N ., Philos Trans R Soc Lond B Biol Sci. October 12, 2020; 375 (1809): 20190559.
Mapping single-cell atlases throughout Metazoa unravels cell type evolution. , Tarashansky AJ., Elife. May 4, 2021; 10
Kindlin2 regulates neural crest specification via integrin-independent regulation of the FGF signaling pathway. , Wang H., Development. May 15, 2021; 148 (10):
BMP signaling is enhanced intracellularly by FHL3 controlling WNT-dependent spatiotemporal emergence of the neural crest. , Alkobtawi M., Cell Rep. June 22, 2021; 35 (12): 109289.
Rspo2 inhibits TCF3 phosphorylation to antagonize Wnt signaling during vertebrate anteroposterior axis specification. , Reis AH., Sci Rep. June 28, 2021; 11 (1): 13433.
Ptk7 Is Dynamically Localized at Neural Crest Cell-Cell Contact Sites and Functions in Contact Inhibition of Locomotion. , Grund A., Int J Mol Sci. August 28, 2021; 22 (17):
Xenopus laevis tadpoles exposed to metamifop: Changes in growth, behavioral endpoints, neurotransmitters, antioxidant system and thyroid development. , Liu R., Ecotoxicol Environ Saf. September 1, 2021; 220 112417.
Sobp modulates the transcriptional activation of Six1 target genes and is required during craniofacial development. , Tavares ALP., Development. September 1, 2021; 148 (17):
Deep learning is widely applicable to phenotyping embryonic development and disease. , Naert T., Development. November 1, 2021; 148 (21):
Collective durotaxis along a self-generated stiffness gradient in vivo. , Shellard A., Nature. December 1, 2021; 600 (7890): 690-694.
16p12.1 Deletion Orthologs are Expressed in Motile Neural Crest Cells and are Important for Regulating Craniofacial Development in Xenopus laevis. , Lasser M., Front Genet. January 1, 2022; 13 833083.
The Ribosomal Protein L5 Functions During Xenopus Anterior Development Through Apoptotic Pathways. , Schreiner C., Front Cell Dev Biol. January 1, 2022; 10 777121.
inka1b expression in the head mesoderm is dispensable for facial cartilage development. , Jeon H., Gene Expr Patterns. January 1, 2022; 45 119262.
Systematic mapping of rRNA 2'-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis. , Delhermite J ., PLoS Genet. January 18, 2022; 18 (1): e1010012.
Multi-omics approach dissects cis-regulatory mechanisms underlying North Carolina macular dystrophy, a retinal enhanceropathy. , Van de Sompele S., Am J Hum Genet. November 3, 2022; 109 (11): 2029-2048.
ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer. , Pandey A., Front Cell Dev Biol. January 1, 2023; 11 1271178.
Zmym4 is required for early cranial gene expression and craniofacial cartilage formation. , Jourdeuil K., Front Cell Dev Biol. January 1, 2023; 11 1274788.
The H2A.Z and NuRD associated protein HMG20A controls early head and heart developmental transcription programs. , Herchenröther A., Nat Commun. January 28, 2023; 14 (1): 472.
Ndst1, a heparan sulfate modification enzyme, regulates neuroectodermal patterning by enhancing Wnt signaling in Xenopus. , Yamamoto T ., Dev Growth Differ. April 1, 2023; 65 (3): 153-160.
The complete dorsal structure is formed from only the blastocoel roof of Xenopus blastula: insight into the gastrulation movement evolutionarily conserved among chordates. , Sato Y., Dev Genes Evol. June 1, 2023; 233 (1): 1-12.
Nitric Oxide Function and Nitric Oxide Synthase Evolution in Aquatic Chordates. , Locascio A., Int J Mol Sci. July 6, 2023; 24 (13):
Paracrine regulation of neural crest EMT by placodal MMP28. , Gouignard N ., PLoS Biol. August 1, 2023; 21 (8): e3002261.
Time-resolved quantitative proteomic analysis of the developing Xenopus otic vesicle reveals putative congenital hearing loss candidates. , Baxi AB., iScience. September 15, 2023; 26 (9): 107665.
Phenotype-genotype relationships in Xenopus sox9 crispants provide insights into campomelic dysplasia and vertebrate jaw evolution. , Hossain N., Dev Growth Differ. October 1, 2023; 65 (8): 481-497.
Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein. , Simon MA., Elife. October 2, 2023; 12
Using Xenopus to discover new candidate genes involved in BOR and other congenital hearing loss syndromes. , Neal SJ., J Exp Zool B Mol Dev Evol. October 13, 2023;
The sulfotransferase XB5850668.L is required to apportion embryonic ectodermal domains. , Marchak A., Dev Dyn. December 1, 2023; 252 (12): 1407-1427.
The early dorsal signal in vertebrate embryos requires endolysosomal membrane trafficking. , Azbazdar Y., Bioessays. January 1, 2024; 46 (1): e2300179.
Prdm15 acts upstream of Wnt4 signaling in anterior neural development of Xenopus laevis. , Saumweber E., Front Cell Dev Biol. January 1, 2024; 12 1316048.
Mechanical Tensions Regulate Gene Expression in the Xenopus laevis Axial Tissues. , Eroshkin FM., Int J Mol Sci. January 10, 2024; 25 (2):
In vitro modeling of cranial placode differentiation: Recent advances, challenges, and perspectives. , Griffin C., Dev Biol. February 1, 2024; 506 20-30.
The RhoGEF Trio is transported by microtubules and affects microtubule stability in migrating neural crest cells. , Gossen S., Cells Dev. March 1, 2024; 177 203899.
Competence for neural crest induction is controlled by hydrostatic pressure through Yap. , Alasaadi DN., Nat Cell Biol. March 18, 2024;
Inhibition of the serine protease HtrA1 by SerpinE2 suggests an extracellular proteolytic pathway in the control of neural crest migration. , Pera EM ., Elife. April 18, 2024; 12