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Summary Anatomy Item Literature (67) Expression Attributions Wiki
XB-ANAT-3805

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Expression of K channels in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting beta-cell line, HIT T15., Ashcroft FM., FEBS Lett. November 7, 1988; 239 (2): 185-9.


Two nonallelic insulin genes in Xenopus laevis are expressed differentially during neurulation in prepancreatic embryos., Shuldiner AR., Proc Natl Acad Sci U S A. September 1, 1991; 88 (17): 7679-83.


Coupling of glucose transport and phosphorylation in Xenopus oocytes and cultured cells: determination of the rate-limiting step., Whitesell RR., J Cell Physiol. December 1, 1993; 157 (3): 509-18.


A mutation in the Glut2 glucose transporter gene of a diabetic patient abolishes transport activity., Mueckler M., J Biol Chem. July 8, 1994; 269 (27): 17765-7.


Coexpression of glucose transporters and glucokinase in Xenopus oocytes indicates that both glucose transport and phosphorylation determine glucose utilization., Morita H., J Clin Invest. October 1, 1994; 94 (4): 1373-82.


Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny., Guz Y., Development. January 1, 1995; 121 (1): 11-8.


Cloning and functional expression of the cDNA encoding an inwardly-rectifying potassium channel expressed in pancreatic beta-cells and in the brain., Bond CT., FEBS Lett. June 19, 1995; 367 (1): 61-6.


Two regions of GLUT 2 glucose transporter protein are responsible for its distinctive affinity for glucose., Buchs A., Endocrinology. October 1, 1995; 136 (10): 4224-30.


Pancreatic islet cells express a family of inwardly rectifying K+ channel subunits which interact to form G-protein-activated channels., Ferrer J., J Biol Chem. November 3, 1995; 270 (44): 26086-91.


Sequence variations in the human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: no association with NIDDM in while Caucasian subjects or evidence of abnormal function when expressed in vitro., Sakura H., Diabetologia. October 1, 1996; 39 (10): 1233-6.


PACAP/VIP receptors in pancreatic beta-cells: their roles in insulin secretion., Inagaki N., Ann N Y Acad Sci. December 26, 1996; 805 44-51; discussion 52-3.


Properties of cloned ATP-sensitive K+ currents expressed in Xenopus oocytes., Gribble FM., J Physiol. January 1, 1997; 498 ( Pt 1) 87-98.


Functional characterization of the transactivation properties of the PDX-1 homeodomain protein., Peshavaria M., Mol Cell Biol. July 1, 1997; 17 (7): 3987-96.


Activation and inhibition of K-ATP currents by guanine nucleotides is mediated by different channel subunits., Trapp S., Proc Natl Acad Sci U S A. August 5, 1997; 94 (16): 8872-7.


The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive K+ channel currents expressed in Xenopus oocytes: a reinterpretation., Gribble FM., J Physiol. October 1, 1997; 504 ( Pt 1) 35-45.


Phentolamine block of KATP channels is mediated by Kir6.2., Proks P., Proc Natl Acad Sci U S A. October 14, 1997; 94 (21): 11716-20.


Primary structure and functional expression of a novel non-selective cation channel., Suzuki M., Biochem Biophys Res Commun. January 6, 1998; 242 (1): 191-6.


herg encodes a K+ current highly conserved in tumors of different histogenesis: a selective advantage for cancer cells?, Bianchi L., Cancer Res. February 15, 1998; 58 (4): 815-22.


Inhibition of the ATP-sensitive potassium channel from mouse pancreatic beta-cells by surfactants., Smith PA., Br J Pharmacol. June 1, 1998; 124 (3): 529-39.


MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit., Gribble FM., Proc Natl Acad Sci U S A. June 9, 1998; 95 (12): 7185-90.


Tissue specificity of sulfonylureas: studies on cloned cardiac and beta-cell K(ATP) channels., Gribble FM., Diabetes. September 1, 1998; 47 (9): 1412-8.


Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP., Trapp S., J Gen Physiol. September 1, 1998; 112 (3): 333-49.                


Mechanism of ATP-sensitive K channel inhibition by sulfhydryl modification., Trapp S., J Gen Physiol. September 1, 1998; 112 (3): 325-32.          


An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2)., Swift GH., Mol Cell Biol. September 1, 1998; 18 (9): 5109-20.


Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA., Gribble FM., J Biol Chem. October 9, 1998; 273 (41): 26383-7.


KATP channel inhibition by ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit., Drain P., Proc Natl Acad Sci U S A. November 10, 1998; 95 (23): 13953-8.


Differential sensitivity of beta-cell and extrapancreatic K(ATP) channels to gliclazide., Gribble FM., Diabetologia. July 1, 1999; 42 (7): 845-8.


Interaction of vanadate with the cloned beta cell K(ATP) channel., Proks P., J Biol Chem. September 3, 1999; 274 (36): 25393-7.


In vitro mechanism of action on insulin release of S-22068, a new putative antidiabetic compound., Le Brigand L., Br J Pharmacol. November 1, 1999; 128 (5): 1021-6.


Altered functional properties of KATP channel conferred by a novel splice variant of SUR1., Sakura H., J Physiol. December 1, 1999; 521 Pt 2 337-50.


Nucleotide modulation of pinacidil stimulation of the cloned K(ATP) channel Kir6.2/SUR2A., Gribble FM., Mol Pharmacol. June 1, 2000; 57 (6): 1256-61.


Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes., Silva JP., Nat Genet. November 1, 2000; 26 (3): 336-40.


Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel., Reimann F., Br J Pharmacol. April 1, 2001; 132 (7): 1542-8.


Glimepiride block of cloned beta-cell, cardiac and smooth muscle K(ATP) channels., Song DK., Br J Pharmacol. May 1, 2001; 133 (1): 193-9.


Effect of repaglinide on cloned beta cell, cardiac and smooth muscle types of ATP-sensitive potassium channels., Dabrowski M., Diabetologia. June 1, 2001; 44 (6): 747-56.


The imidazoline RX871024 stimulates insulin secretion in pancreatic beta-cells from mice deficient in K(ATP) channel function., Efanov AM., Biochem Biophys Res Commun. June 22, 2001; 284 (4): 918-22.


Functional expression and characterization of a voltage-gated CaV1.3 (alpha1D) calcium channel subunit from an insulin-secreting cell line., Scholze A., Mol Endocrinol. July 1, 2001; 15 (7): 1211-21.


Identification and functional analysis of mutations in FAD-binding domain of mitochondrial glycerophosphate dehydrogenase in caucasian patients with type 2 diabetes mellitus., Gudayol M., Endocrine. October 1, 2001; 16 (1): 39-42.


Structural basis for the interference between nicorandil and sulfonylurea action., Reimann F., Diabetes. October 1, 2001; 50 (10): 2253-9.


The novel diazoxide analog 3-isopropylamino-7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide is a selective Kir6.2/SUR1 channel opener., Dabrowski M., Diabetes. June 1, 2002; 51 (6): 1896-906.


The 25-kDa synaptosome-associated protein (SNAP-25) binds and inhibits delayed rectifier potassium channels in secretory cells., Ji J., J Biol Chem. June 7, 2002; 277 (23): 20195-204.


Conserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6., Samaras SE., Mol Cell Biol. July 1, 2002; 22 (13): 4702-13.


Phosphocreatine as a determinant of K(ATP) channel activity in pancreatic beta-cells., Krippeit-Drews P., Pflugers Arch. February 1, 2003; 445 (5): 556-62.


Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides., Reimann F., J Physiol. February 15, 2003; 547 (Pt 1): 159-68.


Direct interaction of target SNAREs with the Kv2.1 channel. Modal regulation of channel activation and inactivation gating., Michaelevski I., J Biol Chem. September 5, 2003; 278 (36): 34320-30.


Potent and selective activation of the pancreatic beta-cell type K(ATP) channel by two novel diazoxide analogues., Dabrowski M., Diabetologia. October 1, 2003; 46 (10): 1375-82.


Wolframin expression induces novel ion channel activity in endoplasmic reticulum membranes and increases intracellular calcium., Osman AA., J Biol Chem. December 26, 2003; 278 (52): 52755-62.


Stichodactyla helianthus peptide, a pharmacological tool for studying Kv3.2 channels., Yan L., Mol Pharmacol. May 1, 2005; 67 (5): 1513-21.


NeuroD1 in the endocrine pancreas: localization and dual function as an activator and repressor., Itkin-Ansari P., Dev Dyn. July 1, 2005; 233 (3): 946-53.


Functional effects of naturally occurring KCNJ11 mutations causing neonatal diabetes on cloned cardiac KATP channels., Tammaro P., J Physiol. February 15, 2006; 571 (Pt 1): 3-14.

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