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Summary Anatomy Item Literature (6783) Expression Attributions Wiki
XB-ANAT-730

Papers associated with visual system (and kcnh2)

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Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action., Thomas D., Br J Pharmacol. June 1, 2004; 142 (3): 485-94.


Inactivation gating determines drug potency: a common mechanism for drug blockade of HERG channels., Yang BF., Acta Pharmacol Sin. May 1, 2004; 25 (5): 554-60.


Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels., Dong DL., Basic Clin Pharmacol Toxicol. May 1, 2004; 94 (5): 209-12.


Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin., Thomas D., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2004; 369 (5): 462-72.


Block of HERG human K(+) channel and IKr of guinea pig cardiomyocytes by chlorpromazine., Lee SY., J Cardiovasc Pharmacol. May 1, 2004; 43 (5): 706-14.


BmTx3, a scorpion toxin with two putative functional faces separately active on A-type K+ and HERG currents., Huys I., Biochem J. March 15, 2004; 378 (Pt 3): 745-52.


Differential recovery of action potential duration and HERG currents from the effects of two methanesulfonamide class III antiarrhythmic agents, KCB-328 and dofetilide., Lee K., J Cardiovasc Pharmacol. November 1, 2003; 42 (5): 648-55.


Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine., Scholz EP., Naunyn Schmiedebergs Arch Pharmacol. November 1, 2003; 368 (5): 404-14.


Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/minK potassium channels., Thomas D., Br J Pharmacol. November 1, 2003; 140 (5): 996-1002.


Inhibition of cloned HERG potassium channels by the antiestrogen tamoxifen., Thomas D., Naunyn Schmiedebergs Arch Pharmacol. July 1, 2003; 368 (1): 41-8.


[Electropharmacological assessment of the risk of drug-induced long-QT syndrome using native cardiac cells and cultured cells expressing HERG channels]., Nakaya H., Nihon Yakurigaku Zasshi. June 1, 2003; 121 (6): 384-92.


The antipsychotic drug chlorpromazine inhibits HERG potassium channels., Thomas D., Br J Pharmacol. June 1, 2003; 139 (3): 567-74.


Negative charges in the transmembrane domains of the HERG K channel are involved in the activation- and deactivation-gating processes., Liu J., J Gen Physiol. June 1, 2003; 121 (6): 599-614.                                  


Voltage-dependent profile of human ether-a-go-go-related gene channel block is influenced by a single residue in the S6 transmembrane domain., Sănchez-Chapula JA., Mol Pharmacol. May 1, 2003; 63 (5): 1051-8.


RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies., Anantharam A., J Biol Chem. April 4, 2003; 278 (14): 11739-45.


Drug- and mutagenesis-induced changes in the selectivity filter of a cardiac two-pore background K+ channel., Hajdú P., Cardiovasc Res. April 1, 2003; 58 (1): 46-54.


Dissociation of E-4031 from the HERG channel caused by mutations of an amino acid results in greater block at high stimulation frequency., Ishii K., Cardiovasc Res. March 1, 2003; 57 (3): 651-9.


Identification, synthesis, and activity of novel blockers of the voltage-gated potassium channel Kv1.5., Peukert S., J Med Chem. February 13, 2003; 46 (4): 486-98.


C-terminal domains implicated in the functional surface expression of potassium channels., Jenke M., EMBO J. February 3, 2003; 22 (3): 395-403.


Interaction between tetraethylammonium and permeant cations at the inactivation gate of the HERG potassium channel., Shimizu H., Jpn J Physiol. February 1, 2003; 53 (1): 25-34.


Relevance of the proximal domain in the amino-terminus of HERG channels for regulation by a phospholipase C-coupled hormone receptor., Gómez-Varela D., FEBS Lett. January 30, 2003; 535 (1-3): 125-30.


Functionally-distinct proton-binding in HERG suggests the presence of two binding sites., Bett GC., Cell Biochem Biophys. January 1, 2003; 39 (3): 183-93.


Inhibition of hEAG1 and hERG1 potassium channels by clofilium and its tertiary analogue LY97241., Gessner G., Br J Pharmacol. January 1, 2003; 138 (1): 161-71.


Inhibitory effect of the class III antiarrhythmic drug nifekalant on HERG channels: mode of action., Kushida S., Eur J Pharmacol. December 13, 2002; 457 (1): 19-27.


The antihistamine fexofenadine does not affect I(Kr) currents in a case report of drug-induced cardiac arrhythmia., Scherer CR., Br J Pharmacol. November 1, 2002; 137 (6): 892-900.


Structural and functional role of the extracellular s5-p linker in the HERG potassium channel., Liu J., J Gen Physiol. November 1, 2002; 120 (5): 723-37.                  


[Cardiotoxicity of lindane, a gamma isomer of hexachlorocyclohexane]., Sauviat MP., J Soc Biol. January 1, 2002; 196 (4): 339-48.


Tissue and species distribution of mRNA for the IKr-like K+ channel, erg., Wymore RS., Circ Res. February 1, 1997; 80 (2): 261-8.

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