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Summary Anatomy Item Literature (6783) Expression Attributions Wiki
XB-ANAT-730

Papers associated with visual system (and kcnh2)

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Tissue and species distribution of mRNA for the IKr-like K+ channel, erg., Wymore RS., Circ Res. February 1, 1997; 80 (2): 261-8.


[Cardiotoxicity of lindane, a gamma isomer of hexachlorocyclohexane]., Sauviat MP., J Soc Biol. January 1, 2002; 196 (4): 339-48.


The antihistamine fexofenadine does not affect I(Kr) currents in a case report of drug-induced cardiac arrhythmia., Scherer CR., Br J Pharmacol. November 1, 2002; 137 (6): 892-900.


Structural and functional role of the extracellular s5-p linker in the HERG potassium channel., Liu J., J Gen Physiol. November 1, 2002; 120 (5): 723-37.                  


Inhibitory effect of the class III antiarrhythmic drug nifekalant on HERG channels: mode of action., Kushida S., Eur J Pharmacol. December 13, 2002; 457 (1): 19-27.


Functionally-distinct proton-binding in HERG suggests the presence of two binding sites., Bett GC., Cell Biochem Biophys. January 1, 2003; 39 (3): 183-93.


Inhibition of hEAG1 and hERG1 potassium channels by clofilium and its tertiary analogue LY97241., Gessner G., Br J Pharmacol. January 1, 2003; 138 (1): 161-71.


Relevance of the proximal domain in the amino-terminus of HERG channels for regulation by a phospholipase C-coupled hormone receptor., Gómez-Varela D., FEBS Lett. January 30, 2003; 535 (1-3): 125-30.


Interaction between tetraethylammonium and permeant cations at the inactivation gate of the HERG potassium channel., Shimizu H., Jpn J Physiol. February 1, 2003; 53 (1): 25-34.


C-terminal domains implicated in the functional surface expression of potassium channels., Jenke M., EMBO J. February 3, 2003; 22 (3): 395-403.


Identification, synthesis, and activity of novel blockers of the voltage-gated potassium channel Kv1.5., Peukert S., J Med Chem. February 13, 2003; 46 (4): 486-98.


Dissociation of E-4031 from the HERG channel caused by mutations of an amino acid results in greater block at high stimulation frequency., Ishii K., Cardiovasc Res. March 1, 2003; 57 (3): 651-9.


Drug- and mutagenesis-induced changes in the selectivity filter of a cardiac two-pore background K+ channel., Hajdú P., Cardiovasc Res. April 1, 2003; 58 (1): 46-54.


RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies., Anantharam A., J Biol Chem. April 4, 2003; 278 (14): 11739-45.


Voltage-dependent profile of human ether-a-go-go-related gene channel block is influenced by a single residue in the S6 transmembrane domain., Sănchez-Chapula JA., Mol Pharmacol. May 1, 2003; 63 (5): 1051-8.


[Electropharmacological assessment of the risk of drug-induced long-QT syndrome using native cardiac cells and cultured cells expressing HERG channels]., Nakaya H., Nihon Yakurigaku Zasshi. June 1, 2003; 121 (6): 384-92.


The antipsychotic drug chlorpromazine inhibits HERG potassium channels., Thomas D., Br J Pharmacol. June 1, 2003; 139 (3): 567-74.


Negative charges in the transmembrane domains of the HERG K channel are involved in the activation- and deactivation-gating processes., Liu J., J Gen Physiol. June 1, 2003; 121 (6): 599-614.                                  


Inhibition of cloned HERG potassium channels by the antiestrogen tamoxifen., Thomas D., Naunyn Schmiedebergs Arch Pharmacol. July 1, 2003; 368 (1): 41-8.


Differential recovery of action potential duration and HERG currents from the effects of two methanesulfonamide class III antiarrhythmic agents, KCB-328 and dofetilide., Lee K., J Cardiovasc Pharmacol. November 1, 2003; 42 (5): 648-55.


Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine., Scholz EP., Naunyn Schmiedebergs Arch Pharmacol. November 1, 2003; 368 (5): 404-14.


Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/minK potassium channels., Thomas D., Br J Pharmacol. November 1, 2003; 140 (5): 996-1002.


BmTx3, a scorpion toxin with two putative functional faces separately active on A-type K+ and HERG currents., Huys I., Biochem J. March 15, 2004; 378 (Pt 3): 745-52.


Inactivation gating determines drug potency: a common mechanism for drug blockade of HERG channels., Yang BF., Acta Pharmacol Sin. May 1, 2004; 25 (5): 554-60.


Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels., Dong DL., Basic Clin Pharmacol Toxicol. May 1, 2004; 94 (5): 209-12.


Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin., Thomas D., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2004; 369 (5): 462-72.


Block of HERG human K(+) channel and IKr of guinea pig cardiomyocytes by chlorpromazine., Lee SY., J Cardiovasc Pharmacol. May 1, 2004; 43 (5): 706-14.


Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action., Thomas D., Br J Pharmacol. June 1, 2004; 142 (3): 485-94.


Activation properties of Kv4.3 channels: time, voltage and [K+]o dependence., Wang S., J Physiol. June 15, 2004; 557 (Pt 3): 705-17.


Molecular basis of slow activation of the human ether-a-go-go related gene potassium channel., Subbiah RN., J Physiol. July 15, 2004; 558 (Pt 2): 417-31.


Inhibition of cardiac HERG potassium channels by the atypical antidepressant trazodone., Zitron E., Naunyn Schmiedebergs Arch Pharmacol. August 1, 2004; 370 (2): 146-56.


Ranolazine: ion-channel-blocking actions and in vivo electrophysiological effects., Schram G., Br J Pharmacol. August 1, 2004; 142 (8): 1300-8.


Structural determinants of HERG channel block by clofilium and ibutilide., Perry M., Mol Pharmacol. August 1, 2004; 66 (2): 240-9.


Probucol aggravates long QT syndrome associated with a novel missense mutation M124T in the N-terminus of HERG., Hayashi K., Clin Sci (Lond). August 1, 2004; 107 (2): 175-82.


Effects of the atrial antiarrhythmic drug AVE0118 on cardiac ion channels., Gögelein H., Naunyn Schmiedebergs Arch Pharmacol. September 1, 2004; 370 (3): 183-92.


The low-potency, voltage-dependent HERG blocker propafenone--molecular determinants and drug trapping., Witchel HJ., Mol Pharmacol. November 1, 2004; 66 (5): 1201-12.


Identification and characterisation of a novel KCNQ1 mutation in a family with Romano-Ward syndrome., Zehelein J., Biochim Biophys Acta. November 5, 2004; 1690 (3): 185-92.


Class Ia anti-arrhythmic drug ajmaline blocks HERG potassium channels: mode of action., Kiesecker C., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 423-35.


Block of wild-type and inactivation-deficient human ether-a-go-go-related gene K+ channels by halofantrine., Sánchez-Chapula JA., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 484-91.


Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by alpha(1A)-adrenoceptors., Thomas D., J Mol Med (Berl). December 1, 2004; 82 (12): 826-37.


A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a-go-go-related gene (HERG) channels., Lin C., Am J Ther. January 1, 2005; 12 (4): 328-36.


The influence of extracellular acidosis on the effect of IKr blockers., Lin C., J Cardiovasc Pharmacol Ther. March 1, 2005; 10 (1): 67-76.


Inhibition of human ether-a-go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine., Choi SY., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.


Molecular mapping of a site for Cd2+-induced modification of human ether-à-go-go-related gene (hERG) channel activation., Fernandez D., J Physiol. September 15, 2005; 567 (Pt 3): 737-55.


Interactions between charged residues in the transmembrane segments of the voltage-sensing domain in the hERG channel., Zhang M., J Membr Biol. October 1, 2005; 207 (3): 169-81.


Inhibitory effect of rhynchophylline on human ether-a-go-go related gene channel., Gui L., Sheng Li Xue Bao. October 25, 2005; 57 (5): 648-52.


Block of HERG channels by berberine: mechanisms of voltage- and state-dependence probed with site-directed mutant channels., Rodriguez-Menchaca A., J Cardiovasc Pharmacol. January 1, 2006; 47 (1): 21-9.


The effects of sevoflurane and propofol on QT interval and heterologously expressed human ether-a-go-go related gene currents in Xenopus oocytes., Yamada M., Anesth Analg. January 1, 2006; 102 (1): 98-103.


Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs., Perry M., Mol Pharmacol. February 1, 2006; 69 (2): 509-19.


Mechanism of action of a novel human ether-a-go-go-related gene channel activator., Casis O., Mol Pharmacol. February 1, 2006; 69 (2): 658-65.

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