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Tissue and species distribution of mRNA for the IKr-like K+ channel, erg. , Wymore RS., Circ Res. February 1, 1997; 80 (2): 261-8.
[Cardiotoxicity of lindane, a gamma isomer of hexachlorocyclohexane]. , Sauviat MP., J Soc Biol. January 1, 2002; 196 (4): 339-48.
The antihistamine fexofenadine does not affect I(Kr) currents in a case report of drug-induced cardiac arrhythmia. , Scherer CR., Br J Pharmacol. November 1, 2002; 137 (6): 892-900.
Structural and functional role of the extracellular s5-p linker in the HERG potassium channel. , Liu J ., J Gen Physiol. November 1, 2002; 120 (5): 723-37.
Inhibitory effect of the class III antiarrhythmic drug nifekalant on HERG channels: mode of action. , Kushida S., Eur J Pharmacol. December 13, 2002; 457 (1): 19-27.
Functionally-distinct proton-binding in HERG suggests the presence of two binding sites. , Bett GC., Cell Biochem Biophys. January 1, 2003; 39 (3): 183-93.
Inhibition of hEAG1 and hERG1 potassium channels by clofilium and its tertiary analogue LY97241. , Gessner G., Br J Pharmacol. January 1, 2003; 138 (1): 161-71.
Relevance of the proximal domain in the amino-terminus of HERG channels for regulation by a phospholipase C-coupled hormone receptor. , Gómez-Varela D., FEBS Lett. January 30, 2003; 535 (1-3): 125-30.
Interaction between tetraethylammonium and permeant cations at the inactivation gate of the HERG potassium channel. , Shimizu H., Jpn J Physiol. February 1, 2003; 53 (1): 25-34.
C-terminal domains implicated in the functional surface expression of potassium channels. , Jenke M., EMBO J. February 3, 2003; 22 (3): 395-403.
Identification, synthesis, and activity of novel blockers of the voltage-gated potassium channel Kv1.5. , Peukert S., J Med Chem. February 13, 2003; 46 (4): 486-98.
Dissociation of E-4031 from the HERG channel caused by mutations of an amino acid results in greater block at high stimulation frequency. , Ishii K., Cardiovasc Res. March 1, 2003; 57 (3): 651-9.
Drug- and mutagenesis-induced changes in the selectivity filter of a cardiac two-pore background K+ channel. , Hajdú P., Cardiovasc Res. April 1, 2003; 58 (1): 46-54.
RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies. , Anantharam A., J Biol Chem. April 4, 2003; 278 (14): 11739-45.
Voltage-dependent profile of human ether-a- go-go-related gene channel block is influenced by a single residue in the S6 transmembrane domain. , Sănchez-Chapula JA., Mol Pharmacol. May 1, 2003; 63 (5): 1051-8.
[Electropharmacological assessment of the risk of drug-induced long-QT syndrome using native cardiac cells and cultured cells expressing HERG channels]. , Nakaya H., Nihon Yakurigaku Zasshi. June 1, 2003; 121 (6): 384-92.
The antipsychotic drug chlorpromazine inhibits HERG potassium channels. , Thomas D., Br J Pharmacol. June 1, 2003; 139 (3): 567-74.
Negative charges in the transmembrane domains of the HERG K channel are involved in the activation- and deactivation-gating processes. , Liu J ., J Gen Physiol. June 1, 2003; 121 (6): 599-614.
Inhibition of cloned HERG potassium channels by the antiestrogen tamoxifen. , Thomas D., Naunyn Schmiedebergs Arch Pharmacol. July 1, 2003; 368 (1): 41-8.
Differential recovery of action potential duration and HERG currents from the effects of two methanesulfonamide class III antiarrhythmic agents, KCB-328 and dofetilide. , Lee K., J Cardiovasc Pharmacol. November 1, 2003; 42 (5): 648-55.
Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine. , Scholz EP., Naunyn Schmiedebergs Arch Pharmacol. November 1, 2003; 368 (5): 404-14.
Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/ minK potassium channels. , Thomas D., Br J Pharmacol. November 1, 2003; 140 (5): 996-1002.
BmTx3, a scorpion toxin with two putative functional faces separately active on A-type K+ and HERG currents. , Huys I., Biochem J. March 15, 2004; 378 (Pt 3): 745-52.
Inactivation gating determines drug potency: a common mechanism for drug blockade of HERG channels. , Yang BF., Acta Pharmacol Sin. May 1, 2004; 25 (5): 554-60.
Acidification alters antiarrhythmic drug blockade of the ether-a- go-go-related Gene ( HERG) Channels. , Dong DL., Basic Clin Pharmacol Toxicol. May 1, 2004; 94 (5): 209-12.
Inhibition of human ether-a- go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin. , Thomas D., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2004; 369 (5): 462-72.
Block of HERG human K(+) channel and IKr of guinea pig cardiomyocytes by chlorpromazine. , Lee SY., J Cardiovasc Pharmacol. May 1, 2004; 43 (5): 706-14.
Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action. , Thomas D., Br J Pharmacol. June 1, 2004; 142 (3): 485-94.
Activation properties of Kv4.3 channels: time, voltage and [K+]o dependence. , Wang S., J Physiol. June 15, 2004; 557 (Pt 3): 705-17.
Molecular basis of slow activation of the human ether-a- go-go related gene potassium channel. , Subbiah RN., J Physiol. July 15, 2004; 558 (Pt 2): 417-31.
Inhibition of cardiac HERG potassium channels by the atypical antidepressant trazodone. , Zitron E., Naunyn Schmiedebergs Arch Pharmacol. August 1, 2004; 370 (2): 146-56.
Ranolazine: ion-channel-blocking actions and in vivo electrophysiological effects. , Schram G., Br J Pharmacol. August 1, 2004; 142 (8): 1300-8.
Structural determinants of HERG channel block by clofilium and ibutilide. , Perry M ., Mol Pharmacol. August 1, 2004; 66 (2): 240-9.
Probucol aggravates long QT syndrome associated with a novel missense mutation M124T in the N-terminus of HERG. , Hayashi K., Clin Sci (Lond). August 1, 2004; 107 (2): 175-82.
Effects of the atrial antiarrhythmic drug AVE0118 on cardiac ion channels. , Gögelein H., Naunyn Schmiedebergs Arch Pharmacol. September 1, 2004; 370 (3): 183-92.
The low-potency, voltage-dependent HERG blocker propafenone--molecular determinants and drug trapping. , Witchel HJ., Mol Pharmacol. November 1, 2004; 66 (5): 1201-12.
Identification and characterisation of a novel KCNQ1 mutation in a family with Romano-Ward syndrome. , Zehelein J., Biochim Biophys Acta. November 5, 2004; 1690 (3): 185-92.
Class Ia anti-arrhythmic drug ajmaline blocks HERG potassium channels: mode of action. , Kiesecker C., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 423-35.
Block of wild-type and inactivation-deficient human ether-a- go-go-related gene K+ channels by halofantrine. , Sánchez-Chapula JA., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 484-91.
Activation of cardiac human ether-a- go-go related gene potassium currents is regulated by alpha(1A)-adrenoceptors. , Thomas D., J Mol Med (Berl). December 1, 2004; 82 (12): 826-37.
A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a- go-go-related gene ( HERG) channels. , Lin C., Am J Ther. January 1, 2005; 12 (4): 328-36.
The influence of extracellular acidosis on the effect of IKr blockers. , Lin C., J Cardiovasc Pharmacol Ther. March 1, 2005; 10 (1): 67-76.
Inhibition of human ether-a- go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine. , Choi SY., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.
Molecular mapping of a site for Cd2+-induced modification of human ether-à- go-go-related gene ( hERG) channel activation. , Fernandez D., J Physiol. September 15, 2005; 567 (Pt 3): 737-55.
Interactions between charged residues in the transmembrane segments of the voltage-sensing domain in the hERG channel. , Zhang M., J Membr Biol. October 1, 2005; 207 (3): 169-81.
Inhibitory effect of rhynchophylline on human ether-a- go-go related gene channel. , Gui L., Sheng Li Xue Bao. October 25, 2005; 57 (5): 648-52.
Block of HERG channels by berberine: mechanisms of voltage- and state-dependence probed with site-directed mutant channels. , Rodriguez-Menchaca A., J Cardiovasc Pharmacol. January 1, 2006; 47 (1): 21-9.
The effects of sevoflurane and propofol on QT interval and heterologously expressed human ether-a- go-go related gene currents in Xenopus oocytes. , Yamada M., Anesth Analg. January 1, 2006; 102 (1): 98-103.
Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs. , Perry M ., Mol Pharmacol. February 1, 2006; 69 (2): 509-19.
Mechanism of action of a novel human ether-a- go-go-related gene channel activator. , Casis O., Mol Pharmacol. February 1, 2006; 69 (2): 658-65.