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Summary Anatomy Item Literature (4906) Expression Attributions Wiki
XB-ANAT-3713

Papers associated with left (and gabarap)

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Differences in affinity and efficacy of benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes., Wafford KA., Mol Pharmacol. February 1, 1993; 43 (2): 240-4.

Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors., Labarca C., Nature. August 10, 1995; 376 (6540): 514-6.

Anion permeation in Ca(2+)-activated Cl(-) channels., Qu Z., J Gen Physiol. December 1, 2000; 116 (6): 825-44.                          

Neuronal representation of odourants in the olfactory bulb of Xenopus laevis tadpoles., Czesnik D., Eur J Neurosci. January 1, 2003; 17 (1): 113-8.                    

Receptor subtype-dependent positive and negative modulation of GABA(A) receptor function by niflumic acid, a nonsteroidal anti-inflammatory drug., Sinkkonen ST., Mol Pharmacol. September 1, 2003; 64 (3): 753-63.

A single M1 residue in the beta2 subunit alters channel gating of GABAA receptor in anesthetic modulation and direct activation., Chang CS., J Biol Chem. October 31, 2003; 278 (44): 42821-8.

The location of a closed channel gate in the GABAA receptor channel., Bali M., J Gen Physiol. February 1, 2007; 129 (2): 145-59.          

About a snail, a toad, and rodents: animal models for adaptation research., Roubos EW., Front Endocrinol (Lausanne). January 1, 2010; 1 4.      

m-Azipropofol (AziPm) a photoactive analogue of the intravenous general anesthetic propofol., Hall MA., J Med Chem. August 12, 2010; 53 (15): 5667-75.              

GABAergic circuits control stimulus-instructed receptive field development in the optic tectum., Richards BA., Nat Neurosci. September 1, 2010; 13 (9): 1098-106.              

Cloning and characterization of GABAA α subunits and GABAB subunits in Xenopus laevis during development., Kaeser GE., Dev Dyn. April 1, 2011; 240 (4): 862-73.                                          

The biochemical anatomy of cortical inhibitory synapses., Heller EA., PLoS One. January 1, 2012; 7 (6): e39572.            

A single amino acid determines the toxicity of Ginkgo biloba extracts., Thompson AJ., FASEB J. May 1, 2012; 26 (5): 1884-91.                    

Partial agonism of taurine at gamma-containing native and recombinant GABAA receptors., Kletke O., PLoS One. January 1, 2013; 8 (4): e61733.            

Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC)., Spurny R., J Biol Chem. March 22, 2013; 288 (12): 8355-8364.                

Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation., Brosnan RJ., BMC Pharmacol Toxicol. November 19, 2014; 15 62.          

The desensitization gate of inhibitory Cys-loop receptors., Gielen M., Nat Commun. April 20, 2015; 6 6829.              

Interactions of L-3,5,3'-Triiodothyronine [corrected], Allopregnanolone, and Ivermectin with the GABAA Receptor: Evidence for Overlapping Intersubunit Binding Modes., Westergard T., PLoS One. September 4, 2015; 10 (9): e0139072.            

The Direct Actions of GABA, 2'-Methoxy-6-Methylflavone and General Anaesthetics at β3γ2L GABAA Receptors: Evidence for Receptors with Different Subunit Stoichiometries., Chua HC., PLoS One. October 20, 2015; 10 (10): e0141359.            

Contrasting actions of a convulsant barbiturate and its anticonvulsant enantiomer on the α1 β3 γ2L GABAA receptor account for their in vivo effects., Desai R., J Physiol. November 15, 2015; 593 (22): 4943-61.

Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels., Bertozzi C., PLoS Biol. March 4, 2016; 14 (3): e1002393.            

Correction for Inhibition Leads to an Allosteric Co-Agonist Model for Pentobarbital Modulation and Activation of α1β3γ2L GABAA Receptors., Ziemba AM., PLoS One. April 21, 2016; 11 (4): e0154031.          

Zolpidem is a potent stoichiometry-selective modulator of α1β3 GABAA receptors: evidence of a novel benzodiazepine site in the α1-α1 interface., Che Has AT., Sci Rep. June 27, 2016; 6 28674.          

Cannabis in epilepsy: From clinical practice to basic research focusing on the possible role of cannabidivarin., Morano A., Epilepsia Open. September 19, 2016; 1 (3-4): 145-151.    

Low Expression in Xenopus Oocytes and Unusual Functional Properties of α1β2γ2 GABAA Receptors with Non-Conventional Subunit Arrangement., Baur R., PLoS One. January 3, 2017; 12 (1): e0170572.        

Molecular tools for GABAA receptors: High affinity ligands for β1-containing subtypes., Simeone X., Sci Rep. July 18, 2017; 7 (1): 5674.            

Synthesis and pharmacological evaluation of neurosteroid photoaffinity ligands., Savechenkov PY., Eur J Med Chem. August 18, 2017; 136 334-347.

The novel isoxazoline ectoparasiticide lotilaner (Credelio™): a non-competitive antagonist specific to invertebrates γ-aminobutyric acid-gated chloride channels (GABACls)., Rufener L., Parasit Vectors. November 1, 2017; 10 (1): 530.              

Azemiopsin, a Selective Peptide Antagonist of Muscle Nicotinic Acetylcholine Receptor: Preclinical Evaluation as a Local Muscle Relaxant., Shelukhina IV., Toxins (Basel). January 7, 2018; 10 (1):                 

Towards functional selectivity for α6β3γ2 GABAA receptors: a series of novel pyrazoloquinolinones., Treven M., Br J Pharmacol. February 1, 2018; 175 (3): 419-428.          

Diversity of Nicotinic Acetylcholine Receptor Positive Allosteric Modulators Revealed by Mutagenesis and a Revised Structural Model., Newcombe J., Mol Pharmacol. February 1, 2018; 93 (2): 128-140.                    

Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels., Fourati Z., Cell Rep. April 24, 2018; 23 (4): 993-1004.                          

Direct neurotransmitter activation of voltage-gated potassium channels., Manville RW., Nat Commun. May 10, 2018; 9 (1): 1847.            

In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders., Grupe M., Eur J Pharmacol. November 15, 2020; 887 173440.

GABAA Receptor Subunit Composition Drives Its Sensitivity to the Insecticide Fipronil., Soualah Z., Front Neurosci. January 1, 2021; 15 768466.                

A critical residue in the α1M2-M3 linker regulating mammalian GABAA receptor pore gating by diazepam., Nors JW., Elife. February 16, 2021; 10                       

Sea anemone Bartholomea annulata venom inhibits voltage-gated Na+ channels and activates GABAA receptors from mammals., Colom-Casasnovas A., Sci Rep. March 30, 2022; 12 (1): 5352.  

Advancements in the use of xenopus oocytes for modelling neurological disease for novel drug discovery., O'Connor EC., Expert Opin Drug Discov. February 1, 2024; 19 (2): 173-187.      

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