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Cytological and biochemical analyses of the maternal-effect mutant embryos with abnormal cleavage furrow formation in Xenopus laevis. , Kubota HY., Dev Biol. March 1, 1991; 144 (1): 145-51.
Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression. , Kornbluth S ., J Cell Biol. May 1, 1994; 125 (4): 705-19.
Purification of a Ran-interacting protein that is required for protein import into the nucleus. , Moore MS ., Proc Natl Acad Sci U S A. October 11, 1994; 91 (21): 10212-6.
A mutant form of the Ran/ TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation. , Dasso M., EMBO J. December 1, 1994; 13 (23): 5732-44.
Regulation of Cdc2/ cyclin B activation by Ran, a Ras-related GTPase. , Clarke PR., J Cell Sci. March 1, 1995; 108 ( Pt 3) 1217-25.
Direct and indirect association of the small GTPase ran with nuclear pore proteins and soluble transport factors: studies in Xenopus laevis egg extracts. , Saitoh H., Mol Biol Cell. September 1, 1996; 7 (9): 1319-34.
RanBP2 associates with Ubc9p and a modified form of RanGAP1. , Saitoh H., Proc Natl Acad Sci U S A. April 15, 1997; 94 (8): 3736-41.
A novel class of RanGTP binding proteins. , Görlich D., J Cell Biol. July 14, 1997; 138 (1): 65-80.
The balance of RanBP1 and RCC1 is critical for nuclear assembly and nuclear transport. , Pu RT., Mol Biol Cell. October 1, 1997; 8 (10): 1955-70.
Xenopus Ran-binding protein 1: molecular interactions and effects on nuclear assembly in Xenopus egg extracts. , Nicolás FJ., J Cell Sci. December 1, 1997; 110 ( Pt 24) 3019-30.
Ubc9p and the conjugation of SUMO-1 to RanGAP1 and RanBP2. , Saitoh H., Curr Biol. January 15, 1998; 8 (2): 121-4.
Modification of Ran GTPase-activating protein by the small ubiquitin-related modifier SUMO-1 requires Ubc9, an E2-type ubiquitin-conjugating enzyme homologue. , Lee GW., J Biol Chem. March 13, 1998; 273 (11): 6503-7.
Xgrip109: a gamma tubulin-associated protein with an essential role in gamma tubulin ring complex (gammaTuRC) assembly and centrosome function. , Martin OC., J Cell Biol. May 4, 1998; 141 (3): 675-87.
The role of the ran GTPase in nuclear assembly and DNA replication: characterisation of the effects of Ran mutants. , Hughes M., J Cell Sci. October 1, 1998; 111 ( Pt 20) 3017-26.
The ran GTPase regulates mitotic spindle assembly. , Kalab P., Curr Biol. May 6, 1999; 9 (9): 481-4.
Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran. , Wilde A., Science. May 21, 1999; 284 (5418): 1359-62.
Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran. , Ohba T., Science. May 21, 1999; 284 (5418): 1356-8.
Ran-GTP stabilises microtubule asters and inhibits nuclear assembly in Xenopus egg extracts. , Zhang C., J Cell Sci. July 1, 1999; 112 ( Pt 14) 2453-61.
Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. , Carazo-Salas RE., Nature. July 8, 1999; 400 (6740): 178-81.
A new role of ran GTPase. , Nishimoto T., Biochem Biophys Res Commun. September 7, 1999; 262 (3): 571-4.
Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts. , Zhang C., Science. May 26, 2000; 288 (5470): 1429-32.
GTP hydrolysis by Ran is required for nuclear envelope assembly. , Hetzer M ., Mol Cell. June 1, 2000; 5 (6): 1013-24.
Role of importin-beta in coupling Ran to downstream targets in microtubule assembly. , Wiese C., Science. January 26, 2001; 291 (5504): 653-6.
Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic- spindle assembly. , Carazo-Salas RE., Nat Cell Biol. March 1, 2001; 3 (3): 228-34.
Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B. , Nemergut ME., Science. May 25, 2001; 292 (5521): 1540-3.
Induction of maturation-promoting factor during Xenopus oocyte maturation uncouples Ca(2+) store depletion from store-operated Ca(2+) entry. , Machaca K ., J Cell Biol. January 7, 2002; 156 (1): 75-85.
Role of importin-beta in the control of nuclear envelope assembly by Ran. , Zhang C., Curr Biol. March 19, 2002; 12 (6): 498-502.
Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts. , Kalab P., Science. March 29, 2002; 295 (5564): 2452-6.
The C-terminal extension of the small GTPase Ran is essential for defining the GDP-bound form. , Nilsson J., J Mol Biol. April 26, 2002; 318 (2): 583-93.
Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells. , Moore W., Curr Biol. August 20, 2002; 12 (16): 1442-7.
Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells. , Gruss OJ ., Nat Cell Biol. November 1, 2002; 4 (11): 871-9.
Chromosomal association of Ran during meiotic and mitotic divisions. , Hinkle B., J Cell Sci. December 1, 2002; 115 (Pt 23): 4685-93.
A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly. , Tsai MY., Nat Cell Biol. March 1, 2003; 5 (3): 242-8.
A mechanism of coupling RCC1 mobility to RanGTP production on the chromatin in vivo. , Li HY., J Cell Biol. March 3, 2003; 160 (5): 635-44.
A role for Ran-GTP and Crm1 in blocking re-replication. , Yamaguchi R., Cell. April 4, 2003; 113 (1): 115-25.
The condensin complex is required for proper spindle assembly and chromosome segregation in Xenopus egg extracts. , Wignall SM., J Cell Biol. June 23, 2003; 161 (6): 1041-51.
The Ran GTPase regulates kinetochore function. , Arnaoutov A., Dev Cell. July 1, 2003; 5 (1): 99-111.
Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity. , Keryer G., Mol Biol Cell. October 1, 2003; 14 (10): 4260-71.
Spatial and temporal control of nuclear envelope assembly by Ran GTPase. , Clarke PR., Symp Soc Exp Biol. January 1, 2004; (56): 193-204.
XRHAMM functions in ran-dependent microtubule nucleation and pole formation during anastral spindle assembly. , Groen AC., Curr Biol. October 26, 2004; 14 (20): 1801-11.
Bipolarization and poleward flux correlate during Xenopus extract spindle assembly. , Mitchison TJ ., Mol Biol Cell. December 1, 2004; 15 (12): 5603-15.
Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts. , Brunet S., Mol Biol Cell. December 1, 2004; 15 (12): 5318-28.
Ran-GTP regulates kinetochore attachment in somatic cells. , Arnaoutov A., Cell Cycle. September 1, 2005; 4 (9): 1161-5.
Active Nercc1 protein kinase concentrates at centrosomes early in mitosis and is necessary for proper spindle assembly. , Roig J., Mol Biol Cell. October 1, 2005; 16 (10): 4827-40.
RanBP3 enhances nuclear export of active (beta)-catenin independently of CRM1. , Hendriksen J., J Cell Biol. December 5, 2005; 171 (5): 785-97.
Aurora A kinase-coated beads function as microtubule-organizing centers and enhance RanGTP-induced spindle assembly. , Tsai MY., Curr Biol. December 6, 2005; 15 (23): 2156-63.
HURP is part of a Ran-dependent complex involved in spindle formation. , Koffa MD., Curr Biol. April 18, 2006; 16 (8): 743-54.
Mechanistic studies of the mitotic activation of Mos. , Yue J., Mol Cell Biol. July 1, 2006; 26 (14): 5300-9.
A picornavirus protein interacts with Ran-GTPase and disrupts nucleocytoplasmic transport. , Porter FW., Proc Natl Acad Sci U S A. August 15, 2006; 103 (33): 12417-22.
The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly. , Orjalo AV., Mol Biol Cell. September 1, 2006; 17 (9): 3806-18.