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Summary Anatomy Item Literature (4753) Expression Attributions Wiki
XB-ANAT-140

Papers associated with genital system (and nbn)

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Resection of DNA double-strand breaks activates Mre11-Rad50-Nbs1- and Rad9-Hus1-Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts., Tatsukawa K., Nucleic Acids Res. April 12, 2024; 52 (6): 3146-3163.                  

POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps., Mann A., Mol Cell. November 17, 2022; 82 (22): 4218-4231.e8.                              

MRN-dependent and independent pathways for recruitment of TOPBP1 to DNA double-strand breaks., Montales K., PLoS One. August 2, 2022; 17 (8): e0271905.                

ZC3HC1 Is a Novel Inherent Component of the Nuclear Basket, Resident in a State of Reciprocal Dependence with TPR., Gunkel P., Cells. July 30, 2021; 10 (8):               

Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining., Zhu S., Nucleic Acids Res. October 13, 2017; 45 (18): 10583-10594.            

Mdc1 modulates the interaction between TopBP1 and the MRN complex during DNA damage checkpoint responses., Choi SH., Biochem Biophys Res Commun. October 7, 2016; 479 (1): 5-11.

Xenopus Mcm10 is a CDK-substrate required for replication fork stability., Chadha GS., Cell Cycle. August 17, 2016; 15 (16): 2183-2195.            

The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks., Lee J., Mol Biol Cell. May 1, 2013; 24 (9): 1343-53.          

A role for the MRN complex in ATR activation via TOPBP1 recruitment., Duursma AM., Mol Cell. April 11, 2013; 50 (1): 116-22.

The MRN-CtIP pathway is required for metaphase chromosome alignment., Rozier L., Mol Cell. March 28, 2013; 49 (6): 1097-107.

Dgp71WD is required for the assembly of the acentrosomal Meiosis I spindle, and is not a general targeting factor for the γ-TuRC., Reschen RF., Biol Open. May 15, 2012; 1 (5): 422-9.          

Analysis of MRE11's function in the 5'-->3' processing of DNA double-strand breaks., Liao S., Nucleic Acids Res. May 1, 2012; 40 (10): 4496-506.                

Time-dependent predominance of nonhomologous DNA end-joining pathways during embryonic development in mice., Chiruvella KK., J Mol Biol. March 30, 2012; 417 (3): 197-211.

Role for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extracts., Kumar S., Cell Cycle. March 15, 2012; 11 (6): 1183-94.

Essential roles of Xenopus TRF2 in telomere end protection and replication., Muraki K., Genes Cells. June 1, 2011; 16 (6): 728-39.

CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts., Ramírez-Lugo JS., Cell Cycle. February 1, 2011; 10 (3): 469-80.

Xenopus DNA2 is a helicase/nuclease that is found in complexes with replication proteins And-1/Ctf4 and Mcm10 and DSB response proteins Nbs1 and ATM., Wawrousek KE., Cell Cycle. March 15, 2010; 9 (6): 1156-66.

The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis., Taylor EM., Nucleic Acids Res. January 1, 2010; 38 (2): 441-54.        

CtIP links DNA double-strand break sensing to resection., You Z., Mol Cell. December 25, 2009; 36 (6): 954-69.

The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM., Yoo HY., Mol Biol Cell. May 1, 2009; 20 (9): 2351-60.

Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity., Jazayeri A., EMBO J. July 23, 2008; 27 (14): 1953-62.              

Rapid activation of ATM on DNA flanking double-strand breaks., You Z., Nat Cell Biol. November 1, 2007; 9 (11): 1311-8.

ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks., Trenz K., EMBO J. April 19, 2006; 25 (8): 1764-74.

Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11., Di Virgilio M., J Cell Biol. December 5, 2005; 171 (5): 765-71.        

ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1., You Z., Mol Cell Biol. July 1, 2005; 25 (13): 5363-79.

Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5., Kapoor TM., J Cell Biol. September 4, 2000; 150 (5): 975-88.                    

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