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Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint. , Byun TS., Genes Dev. May 1, 2005; 19 (9): 1040-52.
Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts. , Arias EE., Genes Dev. January 1, 2005; 19 (1): 114-26.
A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication. , Pacek M., EMBO J. September 15, 2004; 23 (18): 3667-76.
The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation. , Oehlmann M., J Cell Biol. April 26, 2004; 165 (2): 181-90.
DNA damage-induced replication arrest in Xenopus egg extracts. , Stokes MP., J Cell Biol. October 27, 2003; 163 (2): 245-55.
Xenopus Drf1, a regulator of Cdc7, displays checkpoint-dependent accumulation on chromatin during an S-phase arrest. , Yanow SK., J Biol Chem. October 17, 2003; 278 (42): 41083-92.
Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication. , Hashimoto Y., EMBO J. May 15, 2003; 22 (10): 2526-35.
A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication. , Kubota Y., Genes Dev. May 1, 2003; 17 (9): 1141-52.
Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17. , Lee J , Lee J ., Mol Cell. February 1, 2003; 11 (2): 329-40.
CDK- and Cdc45-dependent priming of the MCM complex on chromatin during S-phase in Xenopus egg extracts: possible activation of MCM helicase by association with Cdc45. , Masuda T., Genes Cells. February 1, 2003; 8 (2): 145-61.
An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication. , Costanzo V., Mol Cell. January 1, 2003; 11 (1): 203-13.
The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication. , Van Hatten RA., J Cell Biol. November 25, 2002; 159 (4): 541-7.
Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex. , Chou DM., J Biol Chem. October 25, 2002; 277 (43): 40520-7.
MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts. , Edwards MC., J Biol Chem. September 6, 2002; 277 (36): 33049-57.
Xic1 degradation in Xenopus egg extracts is coupled to initiation of DNA replication. , You Z., Genes Dev. May 15, 2002; 16 (10): 1182-94.
Essential role of Sna41/ Cdc45 in loading of DNA polymerase alpha onto minichromosome maintenance proteins in fission yeast. , Uchiyama M., J Biol Chem. July 13, 2001; 276 (28): 26189-96.
Evidence for sequential action of cdc7 and cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts. , Walter JC ., J Biol Chem. December 15, 2000; 275 (50): 39773-8.
Central role for cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts. , Mimura S., Genes Cells. June 1, 2000; 5 (6): 439-52.
Initiation of eukaryotic DNA replication: origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase alpha. , Walter J., Mol Cell. April 1, 2000; 5 (4): 617-27.
Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk. , Mimura S., EMBO J. October 1, 1998; 17 (19): 5699-707.