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Summary Anatomy Item Literature (3729) Expression Attributions Wiki
XB-ANAT-99

Papers associated with cardiovascular system (and nkx2-5)

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The mitochondrial respiratory chain controls intracellular calcium signaling and NFAT activity essential for heart formation in Xenopus laevis., Chen Y., Mol Cell Biol. September 1, 2007; 27 (18): 6420-32.


Transient early embryonic expression of Nkx2-5 mutations linked to congenital heart defects in human causes heart defects in Xenopus laevis., Bartlett HL., Dev Dyn. September 1, 2007; 236 (9): 2475-84.    


Left-sided embryonic expression of the BCL-6 corepressor, BCOR, is required for vertebrate laterality determination., Hilton EN., Hum Mol Genet. July 15, 2007; 16 (14): 1773-82.              


Xenopus as a model system for vertebrate heart development., Warkman AS., Semin Cell Dev Biol. February 1, 2007; 18 (1): 46-53.      


Myoskeletin, a factor related to Myocardin, is expressed in somites and required for hypaxial muscle formation in Xenopus., Zhao H., Int J Dev Biol. January 1, 2007; 51 (4): 315-20.              


Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart., Wu SM., Cell. December 15, 2006; 127 (6): 1137-50.


Characterization of myeloid cells derived from the anterior ventral mesoderm in the Xenopus laevis embryo., Tashiro S., Dev Growth Differ. October 1, 2006; 48 (8): 499-512.                    


Reduction of XNkx2-10 expression leads to anterior defects and malformation of the embryonic heart., Allen BG., Mech Dev. October 1, 2006; 123 (10): 719-29.          


Retinoic acid signaling is essential for formation of the heart tube in Xenopus., Collop AH., Dev Biol. March 1, 2006; 291 (1): 96-109.                  


A gynogenetic screen to isolate naturally occurring recessive mutations in Xenopus tropicalis., Noramly S., Mech Dev. March 1, 2005; 122 (3): 273-87.              


Myocardin is sufficient and necessary for cardiac gene expression in Xenopus., Small EM., Development. March 1, 2005; 132 (5): 987-97.            


Wnt11 facilitates embryonic stem cell differentiation to Nkx2.5-positive cardiomyocytes., Terami H., Biochem Biophys Res Commun. December 17, 2004; 325 (3): 968-75.


Spatial and temporal expression patterns of Xenopus Nkx-2.3 gene in skin epidermis during metamorphosis., Ma CM., Gene Expr Patterns. November 1, 2004; 5 (1): 129-34.  


Characterization of Xenopus Phox2a and Phox2b defines expression domains within the embryonic nervous system and early heart field., Talikka M., Gene Expr Patterns. September 1, 2004; 4 (5): 601-7.      


Myocardin expression is regulated by Nkx2.5, and its function is required for cardiomyogenesis., Ueyama T., Mol Cell Biol. December 1, 2003; 23 (24): 9222-32.


NKX2.5 mutations in patients with congenital heart disease., McElhinney DB., J Am Coll Cardiol. November 5, 2003; 42 (9): 1650-5.


Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart., Stennard FA., Dev Biol. October 15, 2003; 262 (2): 206-24.  


Amphibian in vitro heart induction: a simple and reliable model for the study of vertebrate cardiac development., Ariizumi T., Int J Dev Biol. September 1, 2003; 47 (6): 405-10.      


Transgenic analysis of the atrialnatriuretic factor (ANF) promoter: Nkx2-5 and GATA-4 binding sites are required for atrial specific expression of ANF., Small EM., Dev Biol. September 1, 2003; 261 (1): 116-31.          


Endothelin-converting enzyme-1 (ECE-1) is a downstream target of the homeobox transcription factor Nkx2-5., Funke-Kaiser H., FASEB J. August 1, 2003; 17 (11): 1487-9.


Csm, a cardiac-specific isoform of the RNA helicase Mov10l1, is regulated by Nkx2.5 in embryonic heart., Ueyama T., J Biol Chem. August 1, 2003; 278 (31): 28750-7.


GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5., Garg V., Nature. July 24, 2003; 424 (6947): 443-7.


PITX2 isoform-specific regulation of atrial natriuretic factor expression: synergism and repression with Nkx2.5., Ganga M., J Biol Chem. June 20, 2003; 278 (25): 22437-45.


Cardiac homeobox gene NKX2-5 mutations and congenital heart disease: associations with atrial septal defect and hypoplastic left heart syndrome., Elliott DA., J Am Coll Cardiol. June 4, 2003; 41 (11): 2072-6.


Expression of Nkx2-5-GFP bacterial artificial chromosome transgenic mice closely resembles endogenous Nkx2-5 gene activity., Chi X., Genesis. April 1, 2003; 35 (4): 220-6.


Nkx2.5 homeoprotein regulates expression of gap junction protein connexin 43 and sarcomere organization in postnatal cardiomyocytes., Kasahara H., J Mol Cell Cardiol. March 1, 2003; 35 (3): 243-56.


Two novel frameshift mutations in NKX2.5 result in novel features including visceral inversus and sinus venosus type ASD., Watanabe Y., J Med Genet. November 1, 2002; 39 (11): 807-11.


The basic-helix-loop-helix transcription factor HAND2 directly regulates transcription of the atrial naturetic peptide gene., Thattaliyath BD., J Mol Cell Cardiol. October 1, 2002; 34 (10): 1335-44.


Csx/Nkx2-5 is required for homeostasis and survival of cardiac myocytes in the adult heart., Toko H., J Biol Chem. July 5, 2002; 277 (27): 24735-43.


Developmentally modulated cardiac conduction failure in transgenic mice with fetal or postnatal overexpression of DNA nonbinding mutant Nkx2.5., Wakimoto H., J Cardiovasc Electrophysiol. July 1, 2002; 13 (7): 682-8.


The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis., Shirai M., J Clin Invest. July 1, 2002; 110 (2): 177-84.


A role for the RNA-binding protein, hermes, in the regulation of heart development., Gerber WV., Dev Biol. July 1, 2002; 247 (1): 116-26.    


Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease., Ikeda Y., Circ J. June 1, 2002; 66 (6): 561-3.


Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation., Habets PE., Genes Dev. May 15, 2002; 16 (10): 1234-46.


Cardiac-specific activity of an Nkx2-5 enhancer requires an evolutionarily conserved Smad binding site., Lien CL., Dev Biol. April 15, 2002; 244 (2): 257-66.


Nkx-2.5 gene induction in mice is mediated by a Smad consensus regulatory region., Liberatore CM., Dev Biol. April 15, 2002; 244 (2): 243-56.


A mouse model of congenital heart disease: cardiac arrhythmias and atrial septal defect caused by haploinsufficiency of the cardiac transcription factor Csx/Nkx2.5., Tanaka M., Cold Spring Harb Symp Quant Biol. January 1, 2002; 67 317-25.


Homeodomain factor Nkx2-5 in heart development and disease., Harvey RP., Cold Spring Harb Symp Quant Biol. January 1, 2002; 67 107-14.


Developmental paradigms in heart disease: insights from tinman., Prall OW., Ann Med. January 1, 2002; 34 (3): 148-56.


Embryonic expression of an Nkx2-5/Cre gene using ROSA26 reporter mice., Moses KA., Genesis. December 1, 2001; 31 (4): 176-80.


The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation., Yamagishi H., Dev Biol. November 15, 2001; 239 (2): 190-203.


Nkx2-5 activity is essential for cardiomyogenesis., Jamali M., J Biol Chem. November 9, 2001; 276 (45): 42252-8.


Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein., Kasahara H., J Clin Invest. July 1, 2001; 108 (2): 189-201.


Elevated expression of Nkx-2.5 in developing myocardial conduction cells., Thomas PS., Anat Rec. July 1, 2001; 263 (3): 307-13.


Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation., Hiroi Y., Nat Genet. July 1, 2001; 28 (3): 276-80.


Inhibition of Wnt activity induces heart formation from posterior mesoderm., Marvin MJ., Genes Dev. February 1, 2001; 15 (3): 316-27.  


COUP-TF1 antagonizes Nkx2.5-mediated activation of the calreticulin gene during cardiac development., Guo L., J Biol Chem. January 26, 2001; 276 (4): 2797-801.


Functional analyses of three Csx/Nkx-2.5 mutations that cause human congenital heart disease., Zhu W., J Biol Chem. November 10, 2000; 275 (45): 35291-6.


Regulation of the tinman homologues in Xenopus embryos., Sparrow DB., Dev Biol. November 1, 2000; 227 (1): 65-79.      


Designation of the anterior/posterior axis in pregastrula Xenopus laevis., Lane MC., Dev Biol. September 1, 2000; 225 (1): 37-58.                        

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