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Recurrent seizure-related GRIN1 variant: Molecular mechanism and targeted therapy. , Xu Y ., Ann Clin Transl Neurol. July 1, 2021; 8 (7): 1480-1494.
Independent pseudogenizations and losses of sox15 during amniote diversification following asymmetric ohnolog evolution. , Ogita Y., BMC Ecol Evol. June 30, 2021; 21 (1): 134.
Fosl1 is vital to heart regeneration upon apex resection in adult Xenopus tropicalis. , Wu HY., NPJ Regen Med. June 29, 2021; 6 (1): 36.
The gastrin-releasing peptide/bombesin system revisited by a reverse-evolutionary study considering Xenopus. , Hirooka A., Sci Rep. June 25, 2021; 11 (1): 13315.
The highly conserved FOXJ1 target CFAP161 is dispensable for motile ciliary function in mouse and Xenopus. , Beckers A., Sci Rep. June 25, 2021; 11 (1): 13333.
Application of Recombinant Rabies Virus to Xenopus Tadpole Brain. , Faulkner RL., eNeuro. June 7, 2021; 8 (4):
Insights from a vertebrate model organism on the molecular mechanisms of whole-body dehydration tolerance. , Luu BE., Mol Cell Biochem. June 1, 2021; 476 (6): 2381-2392.
The Use of Xenopus for Cell Biology Applications. , Philpott A ., Cold Spring Harb Protoc. June 1, 2021; 2021 (6):
Anaplastic lymphoma kinase (alk), a neuroblastoma associated gene, is expressed in neural crest domains during embryonic development of Xenopus. , Moreno MM., Gene Expr Patterns. June 1, 2021; 40 119183.
Altering metabolite distribution at Xenopus cleavage stages affects left- right gene expression asymmetries. , Onjiko RM., Genesis. June 1, 2021; 59 (5-6): e23418.
Thyroid Disrupting Chemicals in Mixture Perturb Thymocyte Differentiation in Xenopus laevis Tadpoles. , McGuire CC., Toxicol Sci. May 27, 2021; 181 (2): 262-272.
The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus. , Zhang F., Proc Natl Acad Sci U S A. May 18, 2021; 118 (20):
Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects. , Lin Y., Proc Natl Acad Sci U S A. May 18, 2021; 118 (20):
Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration in Xenopus laevis larvae. , Hamilton AM ., Elife. May 6, 2021; 10
Mapping single-cell atlases throughout Metazoa unravels cell type evolution. , Tarashansky AJ., Elife. May 4, 2021; 10
Chronic Exposure to Two Gestagens Differentially Alters Morphology and Gene Expression in Silurana tropicalis. , Thomson P., Arch Environ Contam Toxicol. May 1, 2021; 80 (4): 745-759.
The Negative Allosteric Modulator EU1794-4 Reduces Single-Channel Conductance and Ca2+ Permeability of GluN1/GluN2A N-Methyl-d-Aspartate Receptors. , Perszyk RE., Mol Pharmacol. May 1, 2021; 99 (5): 399-411.
Molecular Regulation of Betulinic Acid on α3β4 Nicotinic Acetylcholine Receptors. , Lee S., Molecules. May 1, 2021; 26 (9):
Neurotoxic and convulsant effects induced by jack bean ureases on the mammalian nervous system. , Almeida CGM., Toxicology. April 30, 2021; 454 152737.
WIN55,212-2, a Dual Modulator of Cannabinoid Receptors and G Protein-Coupled Inward Rectifier Potassium Channels. , An D., Biomedicines. April 28, 2021; 9 (5):
Image motion with color contrast suffices to elicit an optokinetic reflex in Xenopus laevis tadpoles. , Knorr AG., Sci Rep. April 19, 2021; 11 (1): 8445.
Bioelectric signaling: Reprogrammable circuits underlying embryogenesis, regeneration, and cancer. , Levin M ., Cell. April 15, 2021;
Basmisanil, a highly selective GABAA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man. , Hipp JF., Sci Rep. April 8, 2021; 11 (1): 7700.
The GARP Domain of the Rod CNG Channel's β1-Subunit Contains Distinct Sites for Outer Segment Targeting and Connecting to the Photoreceptor Disk Rim. , Pearring JN., J Neurosci. April 7, 2021; 41 (14): 3094-3104.
The Xenopus spindle is as dense as the surrounding cytoplasm. , Biswas A ., Dev Cell. April 5, 2021; 56 (7): 967-975.e5.
Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis. , Pizzo L., PLoS Genet. April 5, 2021; 17 (4): e1009112.
Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation. , Dobramysl U., J Cell Biol. April 5, 2021; 220 (4):
Analysis of Visual Collision Avoidance in Xenopus Tadpoles. , Khakhalin AS ., Cold Spring Harb Protoc. April 1, 2021; 2021 (4):
Expansion of NEUROD2 phenotypes to include developmental delay without seizures. , Mis EK., Am J Med Genet A. April 1, 2021; 185 (4): 1076-1080.
Imaging Mitochondrial Dynamics in the Xenopus Central Nervous System (CNS). , Feng MS., Cold Spring Harb Protoc. April 1, 2021; 2021 (4):
Dissecting the Molecular Determinants of GABAA Receptors Current Rundown, a Hallmark of Refractory Human Epilepsy. , Cifelli P., Brain Sci. March 30, 2021; 11 (4):
Microglial trogocytosis and the complement system regulate axonal pruning in vivo. , Lim TK., Elife. March 16, 2021; 10
Intracellular Protein-Lipid Interactions Studied by Rapid-Scan Electron Paramagnetic Resonance Spectroscopy. , Braun TS., J Phys Chem Lett. March 11, 2021; 12 (9): 2471-2475.
Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience. , Willsey HR ., Neuron. March 3, 2021; 109 (5): 788-804.e8.
Light-regulated voltage-gated potassium channels for acute interrogation of channel function in neurons and behavior. , Jerng HH., PLoS One. March 3, 2021; 16 (3): e0248688.
A simple method defines 3D morphology and axon projections of filled neurons in a small CNS volume: Steps toward understanding functional network circuitry. , Conte D., J Neurosci Methods. March 1, 2021; 351 109062.
Mutations in PRDM15 Are a Novel Cause of Galloway-Mowat Syndrome. , Mann N., J Am Soc Nephrol. March 1, 2021; 32 (3): 580-596.
Glutamate transporters have a chloride channel with two hydrophobic gates. , Chen I., Nature. March 1, 2021; 591 (7849): 327-331.
Segregation of brain and organizer precursors is differentially regulated by Nodal signaling at blastula stage. , Castro Colabianchi AM., Biol Open. February 25, 2021; 10 (2):
Synthesis and Pharmacological Evaluation of Novel Non-nucleotide Purine Derivatives as P2X7 Antagonists for the Treatment of Neuroinflammation. , Calzaferri F., J Med Chem. February 25, 2021; 64 (4): 2272-2290.
Biallelic variants in COPB1 cause a novel, severe intellectual disability syndrome with cataracts and variable microcephaly. , Macken WL., Genome Med. February 25, 2021; 13 (1): 34.
Differential Regulation of Human Serotonin Receptor Type 3A by Chanoclavine and Ergonovine. , Eom S., Molecules. February 24, 2021; 26 (5):
Ultrasound activates mechanosensitive TRAAK K+ channels through the lipid membrane. , Sorum B., Proc Natl Acad Sci U S A. February 9, 2021; 118 (6):
Rab11fip5 regulates telencephalon development via ephrinB1 recycling. , Yoon J., Development. February 2, 2021; 148 (3):
Cellular response to spinal cord injury in regenerative and non-regenerative stages in Xenopus laevis. , Edwards-Faret G., Neural Dev. February 2, 2021; 16 (1): 2.
Using an aquatic model, Xenopus laevis, to uncover the role of chromodomain 1 in craniofacial disorders. , Wyatt BH., Genesis. February 1, 2021; 59 (1-2): e23394.
GABAA Receptors Expressed in Oligodendrocytes Cultured from the Neonatal Rat Contain α3 and γ1 Subunits and Present Differential Functional and Pharmacological Properties. , Ordaz RP., Mol Pharmacol. February 1, 2021; 99 (2): 133-146.
Xenopus leads the way: Frogs as a pioneering model to understand the human brain. , Exner CRT., Genesis. February 1, 2021; 59 (1-2): e23405.
Xenopus to the rescue: A model to validate and characterize candidate ciliopathy genes. , Rao VG ., Genesis. February 1, 2021; 59 (1-2): e23414.
Understanding cornea epithelial stem cells and stem cell deficiency: Lessons learned using vertebrate model systems. , Adil MT., Genesis. February 1, 2021; 59 (1-2): e23411.