Papers associated with heart (and kcnh2)

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	Inhibition of human ether-a-go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine., Choi SY., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.
	Class Ia anti-arrhythmic drug ajmaline blocks HERG potassium channels: mode of action., Kiesecker C., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 423-35.
	Block of wild-type and inactivation-deficient human ether-a-go-go-related gene K+ channels by halofantrine., Sánchez-Chapula JA., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 484-91.
	Direct block of hERG potassium channels by the protein kinase C inhibitor bisindolylmaleimide I (GF109203X)., Thomas D., Cardiovasc Res. December 1, 2004; 64 (3): 467-76.
	Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by alpha(1A)-adrenoceptors., Thomas D., J Mol Med (Berl). December 1, 2004; 82 (12): 826-37.
	Identification and characterisation of a novel KCNQ1 mutation in a family with Romano-Ward syndrome., Zehelein J., Biochim Biophys Acta. November 5, 2004; 1690 (3): 185-92.
	Activation properties of Kv4.3 channels: time, voltage and [K+]o dependence., Wang S., J Physiol. June 15, 2004; 557 (Pt 3): 705-17.
	Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin., Thomas D., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2004; 369 (5): 462-72.
	Block of HERG human K(+) channel and IKr of guinea pig cardiomyocytes by chlorpromazine., Lee SY., J Cardiovasc Pharmacol. May 1, 2004; 43 (5): 706-14.
	Physicochemical features of the HERG channel drug binding site., Fernandez D., J Biol Chem. March 12, 2004; 279 (11): 10120-7.
	Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine., Scholz EP., Naunyn Schmiedebergs Arch Pharmacol. November 1, 2003; 368 (5): 404-14.
	Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/minK potassium channels., Thomas D., Br J Pharmacol. November 1, 2003; 140 (5): 996-1002.
	The antipsychotic drug chlorpromazine inhibits HERG potassium channels., Thomas D., Br J Pharmacol. June 1, 2003; 139 (3): 567-74.
	Cloning and functional characterization of the smooth muscle ether-a-go-go-related gene K+ channel. Potential role of a conserved amino acid substitution in the S4 region., Shoeb F., J Biol Chem. January 24, 2003; 278 (4): 2503-14.
	Inhibitory effect of the class III antiarrhythmic drug nifekalant on HERG channels: mode of action., Kushida S., Eur J Pharmacol. December 13, 2002; 457 (1): 19-27.
	Interaction with GM130 during HERG ion channel trafficking. Disruption by type 2 congenital long QT syndrome mutations. Human Ether-à-go-go-Related Gene., Roti EC., J Biol Chem. December 6, 2002; 277 (49): 47779-85.
	Fenamate-induced enhancement of heterologously expressed HERG currents in Xenopus oocytes., Malykhina AP., Eur J Pharmacol. October 11, 2002; 452 (3): 269-77.
	KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current., Angelo K., Biophys J. October 1, 2002; 83 (4): 1997-2006.
	[Evaluation of pro-arrhythmic risk of drugs due to QT interval prolongation by the HERG expression system]., Chachin M., Nihon Yakurigaku Zasshi. June 1, 2002; 119 (6): 345-51.
	Histidines 578 and 587 in the S5-S6 linker of the human Ether-a-gogo Related Gene-1 K+ channels confer sensitivity to reactive oxygen species., Pannaccione A., J Biol Chem. March 15, 2002; 277 (11): 8912-9.
	[Cardiotoxicity of lindane, a gamma isomer of hexachlorocyclohexane]., Sauviat MP., J Soc Biol. January 1, 2002; 196 (4): 339-48.
	Inhibition of cardiac potassium currents by pentobarbital., Bachmann A., Naunyn Schmiedebergs Arch Pharmacol. January 1, 2002; 365 (1): 29-37.
	Characterization of a novel Kv1.5 channel blocker in Xenopus oocytes, CHO cells, human and rat cardiomyocytes., Bachmann A., Naunyn Schmiedebergs Arch Pharmacol. November 1, 2001; 364 (5): 472-8.
	Molecular cloning and expression of cERG, the ether à go-go-related gene from canine myocardium., Zehelein J., Pflugers Arch. May 1, 2001; 442 (2): 188-91.
	High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872., Thomas D., J Pharmacol Exp Ther. May 1, 2001; 297 (2): 753-61.
	Blocking effects of the antiarrhythmic drug propafenone on the HERG potassium channel., Mergenthaler J., Naunyn Schmiedebergs Arch Pharmacol. April 1, 2001; 363 (4): 472-80.
	Short- and long-term effects of amiodarone on the two components of cardiac delayed rectifier K(+) current., Kamiya K., Circulation. March 6, 2001; 103 (9): 1317-24.
	Inhibitory effects of berberine on IK1, IK, and HERG channels of cardiac myocytes., Li BX., Acta Pharmacol Sin. February 1, 2001; 22 (2): 125-31.
	Antiarrhythmic drug carvedilol inhibits HERG potassium channels., Karle CA., Cardiovasc Res. February 1, 2001; 49 (2): 361-70.
	Inhibition of IKs channels by HMR 1556., Gögelein H., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2000; 362 (6): 480-8.
	Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 2nd communication: lack of central nervous system and cardiovascular effects., Kreutner W., Arzneimittelforschung. May 1, 2000; 50 (5): 441-8.
	KChAP as a chaperone for specific K(+) channels., Kuryshev YA., Am J Physiol Cell Physiol. May 1, 2000; 278 (5): C931-41.
	The distinct HERG missense mutation L564P causes long QT syndrome in one French Canadian family., St-Pierre J., Can J Cardiol. March 1, 2000; 16 (3): 307-12.
	Norpropoxyphene-induced cardiotoxicity is associated with changes in ion-selectivity and gating of HERG currents., Ulens C., Cardiovasc Res. December 1, 1999; 44 (3): 568-78.
	Mechanism for the effects of extracellular acidification on HERG-channel function., Jiang M., Am J Physiol. October 1, 1999; 277 (4): H1283-92.
	Pathways of HERG inactivation., Kiehn J., Am J Physiol. July 1, 1999; 277 (1): H199-210.
	Functional analysis of a mouse brain Elk-type K+ channel., Trudeau MC., J Neurosci. April 15, 1999; 19 (8): 2906-18.
	HERG potassium channel activation is shifted by phorbol esters via protein kinase A-dependent pathways., Kiehn J., J Biol Chem. September 25, 1998; 273 (39): 25285-91.
	Differential effects of bupivacaine on cardiac K channels: role of channel inactivation and subunit composition in drug-channel interaction., Lipka LJ., J Cardiovasc Electrophysiol. July 1, 1998; 9 (7): 727-42.
	Effects of the chromanol 293B, a selective blocker of the slow, component of the delayed rectifier K+ current, on repolarization in human and guinea pig ventricular myocytes., Bosch RF., Cardiovasc Res. May 1, 1998; 38 (2): 441-50.
	Voltage-dependent blockade of HERG channels expressed in Xenopus oocytes by external Ca2+ and Mg2+., Ho WK., J Physiol. March 15, 1998; 507 ( Pt 3) (Pt 3): 631-8.
	herg encodes a K+ current highly conserved in tumors of different histogenesis: a selective advantage for cancer cells?, Bianchi L., Cancer Res. February 15, 1998; 58 (4): 815-22.
	Blockade of HERG channels by the class III antiarrhythmic azimilide: mode of action., Busch AE., Br J Pharmacol. January 1, 1998; 123 (1): 23-30.
	Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current., London B., Circ Res. November 1, 1997; 81 (5): 870-8.
	Electrophysiological characterization of an alternatively processed ERG K+ channel in mouse and human hearts., Lees-Miller JP., Circ Res. November 1, 1997; 81 (5): 719-26.
	Suppression of slow delayed rectifier current by a truncated isoform of KvLQT1 cloned from normal human heart., Jiang M., J Biol Chem. September 26, 1997; 272 (39): 24109-12.
	Interactions of the nonsedating antihistamine loratadine with a Kv1.5-type potassium channel cloned from human heart., Lacerda AE., Mol Pharmacol. August 1, 1997; 52 (2): 314-22.
	A minK-HERG complex regulates the cardiac potassium current I(Kr)., McDonald TV., Nature. July 17, 1997; 388 (6639): 289-92.
	A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes., Wang S., J Physiol. July 1, 1997; 502 ( Pt 1) 45-60.
	Suppression of mammalian K+ channel family by ebastine., Ko CM., J Pharmacol Exp Ther. April 1, 1997; 281 (1): 233-44.

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