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Volume sensing in the transient receptor potential vanilloid 4 ion channel is cell type-specific and mediated by an N-terminal volume-sensing domain. , Toft-Bertelsen TL., J Biol Chem. November 29, 2019; 294 (48): 18421-18434.
Modulation of RECK levels in Xenopus A6 cells: effects on MT1-MMP, MMP-2 and pERK levels. , Willson JA., J Biol Res (Thessalon). November 27, 2019; 26 16.
Real time dynamics of Gating-Related conformational changes in CorA. , Rangl M., Elife. November 27, 2019; 8
N6-modified cAMP derivatives that activate protein kinase A also act as full agonists of murine HCN2 channels. , Leypold T., J Biol Chem. November 22, 2019; 294 (47): 17978-17987.
Unique features of the grapevine VvK5.1 channel support novel functions for outward K+ channels in plants. , Villette J., J Exp Bot. November 18, 2019; 70 (21): 6181-6193.
Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex. , Qu Y., Elife. November 13, 2019; 8
Exploring structural dynamics of a membrane protein by combining bioorthogonal chemistry and cysteine mutagenesis. , Gupta K., Elife. November 12, 2019; 8
Analyses of epithelial Na+ channel variants reveal that an extracellular β-ball domain critically regulates ENaC gating. , Wang X ., J Biol Chem. November 8, 2019; 294 (45): 16765-16775.
Structural determinants underlying permeant discrimination of the Cx43 hemichannel. , Nielsen BS., J Biol Chem. November 8, 2019; 294 (45): 16789-16803.
The role of nitric oxide during embryonic wound healing. , Abaffy P., BMC Genomics. November 6, 2019; 20 (1): 815.
Trpc1 as the Missing Link Between the Bmp and Ca2+ Signalling Pathways During Neural Specification in Amphibians. , Néant I ., Sci Rep. November 5, 2019; 9 (1): 16049.
The ion channel function of polycystin-1 in the polycystin-1/polycystin-2 complex. , Wang Z., EMBO Rep. November 5, 2019; 20 (11): e48336.
An intrinsic compartmentalization code for peripheral membrane proteins in photoreceptor neurons. , Maza NA., J Cell Biol. November 4, 2019; 218 (11): 3753-3772.
Kif2a Scales Meiotic Spindle Size in Hymenochirus boettgeri. , Miller KE., Curr Biol. November 4, 2019; 29 (21): 3720-3727.e5.
The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier. , Brohawn SG., Elife. November 1, 2019; 8
Lef1 regulates caveolin expression and caveolin dependent endocytosis, a process necessary for Wnt5a/Ror2 signaling during Xenopus gastrulation. , Puzik K., Sci Rep. October 30, 2019; 9 (1): 15645.
Bioinformatics Screening of Genes Specific for Well-Regenerating Vertebrates Reveals c-answer, a Regulator of Brain Development and Regeneration. , Korotkova DD., Cell Rep. October 22, 2019; 29 (4): 1027-1040.e6.
Extraocular, rod-like photoreceptors in a flatworm express xenopsin photopigment. , Rawlinson KA., Elife. October 22, 2019; 8
N-Glycosylation of TREK-1/hK2P2.1 Two-Pore-Domain Potassium (K2P) Channels. , Wiedmann F., Int J Mol Sci. October 20, 2019; 20 (20):
Proliferative regulation of alveolar epithelial type 2 progenitor cells by human Scnn1d gene. , Zhao R., Theranostics. October 18, 2019; 9 (26): 8155-8170.
Full-Length P2X7 Structures Reveal How Palmitoylation Prevents Channel Desensitization. , McCarthy AE., Cell. October 17, 2019; 179 (3): 659-670.e13.
Incorporation of one N-glycosylation-deficient subunit within a tetramer of HCN2 channel is tolerated. , Kaku R., Neuroreport. October 16, 2019; 30 (15): 998-1003.
Update on the Role of the Non-Canonical Wnt/Planar Cell Polarity Pathway in Neural Tube Defects. , Wang M., Cells. October 4, 2019; 8 (10):
Bayesian Confidence Intervals for Multiplexed Proteomics Integrate Ion-statistics with Peptide Quantification Concordance. , Peshkin L ., Mol Cell Proteomics. October 1, 2019; 18 (10): 2108-2120.
Novel vectors for functional interrogation of Xenopus ORFeome coding sequences. , Sterner ZR., Genesis. October 1, 2019; 57 (10): e23329.
Understanding cornea homeostasis and wound healing using a novel model of stem cell deficiency in Xenopus. , Adil MT., Exp Eye Res. October 1, 2019; 187 107767.
Skeletal muscle differentiation drives a dramatic downregulation of RNA polymerase III activity and differential expression of Polr3g isoforms. , McQueen C., Dev Biol. October 1, 2019; 454 (1): 74-84.
NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress. , Han D., Elife. September 30, 2019; 8
Novel information on the morphology, phylogeny and distribution of camallanid nematodes from marine and freshwater hosts in South Africa, including the description of Camallanus sodwanaensis n. sp. , Svitin R., Int J Parasitol Parasites Wildl. September 30, 2019; 10 263-273.
ΔN- Tp63 Mediates Wnt/ β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia. , Haas M., Cell Rep. September 24, 2019; 28 (13): 3338-3352.e6.
Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals. , Gentsch GE ., Nat Commun. September 19, 2019; 10 (1): 4269.
Identification of Aethina tumida Kir Channels as Putative Targets of the Bee Venom Peptide Tertiapin Using Structure-Based Virtual Screening Methods. , Doupnik CA., Toxins (Basel). September 19, 2019; 11 (9):
BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers. , Kuznetsov JN ., Sci Adv. September 18, 2019; 5 (9): eaax1738.
VX-770-mediated potentiation of numerous human CFTR disease mutants is influenced by phosphorylation level. , Cui G., Sci Rep. September 17, 2019; 9 (1): 13460.
Overcoming chromatin barriers. , de Jong BE., Elife. September 13, 2019; 8
Calcium-driven regulation of voltage-sensing domains in BK channels. , Lorenzo-Ceballos Y., Elife. September 11, 2019; 8
Conservation and divergence of protein pathways in the vertebrate heart. , Federspiel JD., PLoS Biol. September 6, 2019; 17 (9): e3000437.
Regulation of Eag1 gating by its intracellular domains. , Whicher JR., Elife. September 6, 2019; 8
Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome. , Greenberg RS., Cell. September 5, 2019; 178 (6): 1421-1436.e24.
The molecular determinants of R-roscovitine block of hERG channels. , Cernuda B., PLoS One. September 3, 2019; 14 (9): e0217733.
Xenopus fraseri: Mr. Fraser, where did your frog come from? , Evans BJ ., PLoS One. September 3, 2019; 14 (9): e0220892.
Polyamine biosynthesis in Xenopus laevis: the xlAZIN2/xlODC2 gene encodes a lysine/ornithine decarboxylase. , Lambertos A., PLoS One. September 3, 2019; 14 (9): e0218500.
Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2. , Khetchoumian K., Nat Commun. September 3, 2019; 10 (1): 3960.
The SNPs in myoD gene from normal muscle developing individuals have no effect on muscle mass. , Ding S., BMC Genet. September 2, 2019; 20 (1): 72.
PTK7 proteolytic fragment proteins function during early Xenopus development. , Lichtig H., Dev Biol. September 1, 2019; 453 (1): 48-55.
Catalyst-free Click PEGylation reveals substantial mitochondrial ATP synthase sub-unit alpha oxidation before and after fertilisation. , Cobley JN ., Redox Biol. September 1, 2019; 26 101258.
Lineage tracing of sclerotome cells in amphibian reveals that multipotent somitic cells originate from lateral somitic frontier. , Della Gaspera B ., Dev Biol. September 1, 2019; 453 (1): 11-18.
SLC12A ion transporter mutations in sporadic and familial human congenital hydrocephalus. , Jin SC., Mol Genet Genomic Med. September 1, 2019; 7 (9): e892.
The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10. , Paulson CN., Open Biol. August 30, 2019; 9 (8): 190117.
Microsyntenic Clusters Reveal Conservation of lncRNAs in Chordates Despite Absence of Sequence Conservation. , Herrera-Úbeda C., Biology (Basel). August 24, 2019; 8 (3):