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The connexin46 mutant, Cx46T19M, causes loss of gap junction function and alters hemi-channel gating. , Tong JJ., J Membr Biol. February 1, 2015; 248 (1): 145-55.
Connexin 46 ( cx46) gap junctions provide a pathway for the delivery of glutathione to the lens nucleus. , Slavi N., J Biol Chem. November 21, 2014; 289 (47): 32694-702.
Functional characterization of an AQP0 missense mutation, R33C, that causes dominant congenital lens cataract, reveals impaired cell-to-cell adhesion. , Kumari SS., Exp Eye Res. November 1, 2013; 116 371-85.
Properties of two cataract-associated mutations located in the NH2 terminus of connexin 46. , Tong JJ., Am J Physiol Cell Physiol. May 1, 2013; 304 (9): C823-32.
Cataract-associated D3Y mutation of human connexin46 (hCx46) increases the dye coupling of gap junction channels and suppresses the voltage sensitivity of hemichannels. , Schlingmann B., J Bioenerg Biomembr. October 1, 2012; 44 (5): 607-14.
Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2. , Xia CH., PLoS One. January 1, 2012; 7 (12): e52894.
Different consequences of cataract-associated mutations at adjacent positions in the first extracellular boundary of connexin50. , Tong JJ., Am J Physiol Cell Physiol. May 1, 2011; 300 (5): C1055-64.
Properties of connexin 46 hemichannels in dissociated lens fiber cells. , Ebihara L., Invest Ophthalmol Vis Sci. February 1, 2011; 52 (2): 882-9.
The GJA8 allele encoding CX50I247M is a rare polymorphism, not a cataract-causing mutation. , Graw J., Mol Vis. May 18, 2009; 15 1881-5.
Interaction between Connexin50 and mitogen-activated protein kinase signaling in lens homeostasis. , Shakespeare TI., Mol Biol Cell. May 1, 2009; 20 (10): 2582-92.
The cataract causing Cx50-S50P mutant inhibits Cx43 and intercellular communication in the lens epithelium. , DeRosa AM., Exp Cell Res. April 1, 2009; 315 (6): 1063-75.
Connexin mutation that causes dominant congenital cataracts inhibits gap junctions, but not hemichannels, in a dominant negative manner. , Banks EA., J Cell Sci. February 1, 2009; 122 (Pt 3): 378-88.
A novel connexin50 mutation associated with congenital nuclear pulverulent cataracts. , Arora A., J Med Genet. March 1, 2008; 45 (3): 155-60.
The cataract-inducing S50P mutation in Cx50 dominantly alters the channel gating of wild-type lens connexins. , DeRosa AM., J Cell Sci. December 1, 2007; 120 (Pt 23): 4107-16.
Transgenic overexpression of connexin50 induces cataracts. , Chung J., Exp Eye Res. March 1, 2007; 84 (3): 513-28.
Regulation of connexin hemichannels by monovalent cations. , Srinivas M., J Gen Physiol. January 1, 2006; 127 (1): 67-75.
Connexins are mechanosensitive. , Bao L., Am J Physiol Cell Physiol. November 1, 2004; 287 (5): C1389-95.
Exchange of gating properties between rat cx46 and chicken cx45.6. , Tong JJ., Biophys J. October 1, 2004; 87 (4): 2397-406.
Hemichannel and junctional properties of connexin 50. , Beahm DL., Biophys J. April 1, 2002; 82 (4): 2016-31.
Inhibition of gap junction hemichannels by chloride channel blockers. , Eskandari S., J Membr Biol. January 15, 2002; 185 (2): 93-102.
Co-expression of lens fiber connexins modifies hemi-gap-junctional channel behavior. , Ebihara L., Biophys J. January 1, 1999; 76 (1 Pt 1): 198-206.
Spatial differences in gap junction gating in the lens are a consequence of connexin cleavage. , Lin JS., Eur J Cell Biol. August 1, 1998; 76 (4): 246-50.
Changes in lens connexin expression lead to increased gap junctional voltage dependence and conductance. , Donaldson PJ., Am J Physiol. September 1, 1995; 269 (3 Pt 1): C590-600.
Bovine connexin44, a lens gap junction protein: molecular cloning, immunologic characterization, and functional expression. , Gupta VK., Invest Ophthalmol Vis Sci. September 1, 1994; 35 (10): 3747-58.
Selective interactions among the multiple connexin proteins expressed in the vertebrate lens: the second extracellular domain is a determinant of compatibility between connexins. , White TW., J Cell Biol. May 1, 1994; 125 (4): 879-92.
Mouse Cx50, a functional member of the connexin family of gap junction proteins, is the lens fiber protein MP70. , White TW., Mol Biol Cell. July 1, 1992; 3 (7): 711-20.
Connexin46, a novel lens gap junction protein, induces voltage-gated currents in nonjunctional plasma membrane of Xenopus oocytes. , Paul DL., J Cell Biol. November 1, 1991; 115 (4): 1077-89.