Papers associated with egg (and cdc45)

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	Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk., Mimura S., EMBO J. October 1, 1998; 17 (19): 5699-707.
	Initiation of eukaryotic DNA replication: origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase alpha., Walter J., Mol Cell. April 1, 2000; 5 (4): 617-27.
	Central role for cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts., Mimura S., Genes Cells. June 1, 2000; 5 (6): 439-52.
	Evidence for sequential action of cdc7 and cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts., Walter JC., J Biol Chem. December 15, 2000; 275 (50): 39773-8.
	Essential role of Sna41/Cdc45 in loading of DNA polymerase alpha onto minichromosome maintenance proteins in fission yeast., Uchiyama M., J Biol Chem. July 13, 2001; 276 (28): 26189-96.
	Xic1 degradation in Xenopus egg extracts is coupled to initiation of DNA replication., You Z., Genes Dev. May 15, 2002; 16 (10): 1182-94.
	MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts., Edwards MC., J Biol Chem. September 6, 2002; 277 (36): 33049-57.
	Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex., Chou DM., J Biol Chem. October 25, 2002; 277 (43): 40520-7.
	The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication., Van Hatten RA., J Cell Biol. November 25, 2002; 159 (4): 541-7.
	An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication., Costanzo V., Mol Cell. January 1, 2003; 11 (1): 203-13.
	Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17., Lee J, Lee J., Mol Cell. February 1, 2003; 11 (2): 329-40.
	CDK- and Cdc45-dependent priming of the MCM complex on chromatin during S-phase in Xenopus egg extracts: possible activation of MCM helicase by association with Cdc45., Masuda T., Genes Cells. February 1, 2003; 8 (2): 145-61.
	A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication., Kubota Y., Genes Dev. May 1, 2003; 17 (9): 1141-52.
	Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication., Hashimoto Y., EMBO J. May 15, 2003; 22 (10): 2526-35.
	Xenopus Drf1, a regulator of Cdc7, displays checkpoint-dependent accumulation on chromatin during an S-phase arrest., Yanow SK., J Biol Chem. October 17, 2003; 278 (42): 41083-92.
	DNA damage-induced replication arrest in Xenopus egg extracts., Stokes MP., J Cell Biol. October 27, 2003; 163 (2): 245-55.
	The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation., Oehlmann M., J Cell Biol. April 26, 2004; 165 (2): 181-90.
	A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication., Pacek M., EMBO J. September 15, 2004; 23 (18): 3667-76.
	Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts., Arias EE., Genes Dev. January 1, 2005; 19 (1): 114-26.
	Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint., Byun TS., Genes Dev. May 1, 2005; 19 (9): 1040-52.
	Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome., Sangrithi MN., Cell. June 17, 2005; 121 (6): 887-98.
	Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response., Lee J., Mol Biol Cell. November 1, 2005; 16 (11): 5269-82.
	Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication., Pacek M., Mol Cell. February 17, 2006; 21 (4): 581-7.
	Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint., Petersen P., Mol Cell Biol. March 1, 2006; 26 (5): 1997-2011.
	The DNA polymerase activity of Pol epsilon holoenzyme is required for rapid and efficient chromosomal DNA replication in Xenopus egg extracts., Shikata K., BMC Biochem. May 1, 2006; 7 21.
	Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress., Woodward AM., J Cell Biol. June 5, 2006; 173 (5): 673-83.
	The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication., Matsuno K., Mol Cell Biol. July 1, 2006; 26 (13): 4843-52.
	De novo assembly of genuine replication forks on an immobilized circular plasmid in Xenopus egg extracts., Zembutsu A., Nucleic Acids Res. July 26, 2006; 34 (13): e91.
	Plx1 is required for chromosomal DNA replication under stressful conditions., Trenz K., EMBO J. March 19, 2008; 27 (6): 876-85.
	Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion., Errico A., EMBO J. December 2, 2009; 28 (23): 3681-92.
	Treslin collaborates with TopBP1 in triggering the initiation of DNA replication., Kumagai A., Cell. February 5, 2010; 140 (3): 349-59.
	The DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation., Chowdhury A., Mol Cell Biol. March 1, 2010; 30 (6): 1495-507.
	GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication., Balestrini A., Nat Cell Biol. May 1, 2010; 12 (5): 484-91.
	Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex., Kundu LR., Nucleic Acids Res. September 1, 2010; 38 (16): 5409-18.
	MCM2-7 form double hexamers at licensed origins in Xenopus egg extract., Gambus A., J Biol Chem. April 1, 2011; 286 (13): 11855-64.
	Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication., Kumagai A., J Cell Biol. June 13, 2011; 193 (6): 995-1007.
	RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks., Hashimoto Y., Nat Struct Mol Biol. December 4, 2011; 19 (1): 17-24.
	The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks., Lee J., Mol Biol Cell. May 1, 2013; 24 (9): 1343-53.
	DNA topoisomerase IIα controls replication origin cluster licensing and firing time in Xenopus egg extracts., Gaggioli V., Nucleic Acids Res. August 1, 2013; 41 (15): 7313-31.
	Depletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts., Taylor EM., Nucleic Acids Res. September 1, 2013; 41 (16): 7725-37.
	Mta2 promotes Tipin-dependent maintenance of replication fork integrity., Errico A., Cell Cycle. January 1, 2014; 13 (13): 2120-8.
	Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1., Poh WT., Open Biol. January 8, 2014; 4 (1): 130138.
	NCOA4 transcriptional coactivator inhibits activation of DNA replication origins., Bellelli R., Mol Cell. July 3, 2014; 55 (1): 123-37.
	Protein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiation., Gao Y., J Biol Chem. December 26, 2014; 289 (52): 35987-6000.
	RecQ4 promotes the conversion of the pre-initiation complex at a site-specific origin for DNA unwinding in Xenopus egg extracts., Sanuki Y., Cell Cycle. January 1, 2015; 14 (7): 1010-23.
	DNA interstrand cross-link repair requires replication-fork convergence., Zhang J., Nat Struct Mol Biol. March 1, 2015; 22 (3): 242-7.
	The mechanism of DNA replication termination in vertebrates., Dewar JM., Nature. September 17, 2015; 525 (7569): 345-50.
	Studying essential DNA metabolism proteins in Xenopus egg extract., Sannino V., Int J Dev Biol. January 1, 2016; 60 (7-8-9): 221-227.
	Structure of human Cdc45 and implications for CMG helicase function., Simon AC., Nat Commun. May 18, 2016; 7 11638.
	Xenopus Mcm10 is a CDK-substrate required for replication fork stability., Chadha GS., Cell Cycle. August 17, 2016; 15 (16): 2183-2195.

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