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Summary Anatomy Item Literature (2432) Expression Attributions Wiki
XB-ANAT-63

Papers associated with heart (and pitx2)

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Cilia-driven leftward flow determines laterality in Xenopus., Schweickert A., Curr Biol. January 9, 2007; 17 (1): 60-6.        

Subtilisin-like proprotein convertase activity is necessary for left-right axis determination in Xenopus neurula embryos., Toyoizumi R., Dev Genes Evol. October 1, 2006; 216 (10): 607-22.

Left-right lineage analysis of the embryonic Xenopus heart reveals a novel framework linking congenital cardiac defects and laterality disease., Ramsdell AF., Development. April 1, 2006; 133 (7): 1399-410.                    

Xenopus nodal related-1 is indispensable only for left-right axis determination., Toyoizumi R., Int J Dev Biol. January 1, 2005; 49 (8): 923-38.                

ALK4 functions as a receptor for multiple TGF beta-related ligands to regulate left-right axis determination and mesoderm induction in Xenopus., Chen Y., Dev Biol. April 15, 2004; 268 (2): 280-94.      

Pitx2c attenuation results in cardiac defects and abnormalities of intestinal orientation in developing Xenopus laevis., Dagle JM., Dev Biol. October 15, 2003; 262 (2): 268-81.

Left and right contributions to the Xenopus heart: implications for asymmetric morphogenesis., Gormley JP., Dev Genes Evol. August 1, 2003; 213 (8): 390-8.

PITX2 isoform-specific regulation of atrial natriuretic factor expression: synergism and repression with Nkx2.5., Ganga M., J Biol Chem. June 20, 2003; 278 (25): 22437-45.

Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein., Mogi K., Int J Dev Biol. February 1, 2003; 47 (1): 15-29.                  

PKCgamma regulates syndecan-2 inside-out signaling during xenopus left-right development., Kramer KL., Cell. December 27, 2002; 111 (7): 981-90.                

Pitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushions., Liu C., Development. November 1, 2002; 129 (21): 5081-91.

Asymmetries in H+/K+-ATPase and cell membrane potentials comprise a very early step in left-right patterning., Levin M., Cell. October 4, 2002; 111 (1): 77-89.              

Directionality of heart looping: effects of Pitx2c misexpression on flectin asymmetry and midline structures., Linask KK., Dev Biol. June 15, 2002; 246 (2): 407-17.

Xenopus Brachyury regulates mesodermal expression of Zic3, a gene controlling left-right asymmetry., Kitaguchi T., Dev Growth Differ. February 1, 2002; 44 (1): 55-61.        

Ectodermal syndecan-2 mediates left-right axis formation in migrating mesoderm as a cell-nonautonomous Vg1 cofactor., Kramer KL., Dev Cell. January 1, 2002; 2 (1): 115-24.  

Calmodulin binds to inv protein: implication for the regulation of inv function., Yasuhiko Y., Dev Growth Differ. December 1, 2001; 43 (6): 671-81.                

Differential gene expression of Xenopus Pitx1, Pitx2b and Pitx2c during cement gland, stomodeum and pituitary development., Schweickert A., Mech Dev. September 1, 2001; 107 (1-2): 191-4.    

A role for BMP signalling in heart looping morphogenesis in Xenopus., Breckenridge RA., Dev Biol. April 1, 2001; 232 (1): 191-203.          

Zic3 is involved in the left-right specification of the Xenopus embryo., Kitaguchi T., Development. November 1, 2000; 127 (22): 4787-95.              

Regulation of gut and heart left-right asymmetry by context-dependent interactions between xenopus lefty and BMP4 signaling., Branford WW., Dev Biol. July 15, 2000; 223 (2): 291-306.              

More than 95% reversal of left-right axis induced by right-sided hypodermic microinjection of activin into Xenopus neurula embryos., Toyoizumi R., Dev Biol. May 15, 2000; 221 (2): 321-36.                

Mesendoderm and left-right brain, heart and gut development are differentially regulated by pitx2 isoforms., Essner JJ., Development. March 1, 2000; 127 (5): 1081-93.      

The lefty-related factor Xatv acts as a feedback inhibitor of nodal signaling in mesoderm induction and L-R axis development in xenopus., Cheng AM., Development. March 1, 2000; 127 (5): 1049-61.                

Embryonic origins of spleen asymmetry., Patterson KD., Development. January 1, 2000; 127 (1): 167-75.            

Pitx2 isoforms: involvement of Pitx2c but not Pitx2a or Pitx2b in vertebrate left-right asymmetry., Schweickert A., Mech Dev. January 1, 2000; 90 (1): 41-51.  

Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis., Lin CR., Nature. September 16, 1999; 401 (6750): 279-82.

Cerberus regulates left-right asymmetry of the embryonic head and heart., Zhu L., Curr Biol. September 9, 1999; 9 (17): 931-8.

Retinoic acid is required in the mouse embryo for left-right asymmetry determination and heart morphogenesis., Chazaud C., Development. June 1, 1999; 126 (12): 2589-96.

The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping., Campione M., Development. March 1, 1999; 126 (6): 1225-34.            

Pitx2 determines left-right asymmetry of internal organs in vertebrates., Ryan AK., Nature. August 6, 1998; 394 (6693): 545-51.

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