Results 1 - 21 of 21 results
Two isoforms of the mouse ether-a- go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current. , London B., Circ Res. November 1, 1997; 81 (5): 870-8.
herg encodes a K+ current highly conserved in tumors of different histogenesis: a selective advantage for cancer cells? , Bianchi L., Cancer Res. February 15, 1998; 58 (4): 815-22.
Voltage-dependent blockade of HERG channels expressed in Xenopus oocytes by external Ca2+ and Mg2+. , Ho WK., J Physiol. March 15, 1998; 507 ( Pt 3) (Pt 3): 631-8.
Functional analysis of a mouse brain Elk-type K+ channel. , Trudeau MC., J Neurosci. April 15, 1999; 19 (8): 2906-18.
Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 2nd communication: lack of central nervous system and cardiovascular effects. , Kreutner W., Arzneimittelforschung. May 1, 2000; 50 (5): 441-8.
Inhibitory effects of berberine on IK1, IK, and HERG channels of cardiac myocytes. , Li BX., Acta Pharmacol Sin. February 1, 2001; 22 (2): 125-31.
Antiarrhythmic drug carvedilol inhibits HERG potassium channels. , Karle CA., Cardiovasc Res. February 1, 2001; 49 (2): 361-70.
High-affinity blockade of human ether-a- go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872. , Thomas D., J Pharmacol Exp Ther. May 1, 2001; 297 (2): 753-61.
Cloning and functional characterization of the smooth muscle ether-a- go-go-related gene K+ channel. Potential role of a conserved amino acid substitution in the S4 region. , Shoeb F., J Biol Chem. January 24, 2003; 278 (4): 2503-14.
Inhibition of human ether-a- go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin. , Thomas D., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2004; 369 (5): 462-72.
Block of wild-type and inactivation-deficient human ether-a- go-go-related gene K+ channels by halofantrine. , Sánchez-Chapula JA., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 484-91.
Activation of cardiac human ether-a- go-go related gene potassium currents is regulated by alpha(1A)-adrenoceptors. , Thomas D., J Mol Med (Berl). December 1, 2004; 82 (12): 826-37.
Inhibition of human ether-a- go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine. , Choi SY., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.
Activation of human ether-a- go-go-related gene potassium channels by the diphenylurea 1,3- bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643). , Hansen RS., Mol Pharmacol. January 1, 2006; 69 (1): 266-77.
Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine. , Lee SY., Br J Pharmacol. June 1, 2006; 148 (4): 499-509.
Molecular interaction of droperidol with human ether-a- go-go-related gene channels: prolongation of action potential duration without inducing early afterdepolarization. , Schwoerer AP., Anesthesiology. May 1, 2007; 106 (5): 967-76.
Molecular coupling in the human ether-a- go-go-related gene-1 ( hERG1) K+ channel inactivation pathway. , Ferrer T., J Biol Chem. November 11, 2011; 286 (45): 39091-9.
Kcnh1 voltage-gated potassium channels are essential for early zebrafish development. , Stengel R., J Biol Chem. October 12, 2012; 287 (42): 35565-35575.
Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel. , Park MH., J Pharmacol Sci. September 20, 2013; 123 (1): 67-77.
Concatenated hERG1 tetramers reveal stoichiometry of altered channel gating by RPR-260243. , Wu W., Mol Pharmacol. January 1, 2015; 87 (3): 401-9.
Eag Domains Regulate LQT Mutant hERG Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. , Liu QN., PLoS One. April 22, 2015; 10 (4): e0123951.