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The nuclear envelope prevents reinitiation of replication by regulating the binding of MCM3 to chromatin in Xenopus egg extracts. , Madine MA., Curr Biol. November 1, 1995; 5 (11): 1270-9.
DNA replication licensing factor. , Chong JP., Prog Cell Cycle Res. January 1, 1996; 2 83-90.
Human replication proteins hCdc21, hCdc46 and P1Mcm3 bind chromatin uniformly before S-phase and are displaced locally during DNA replication. , Krude T., J Cell Sci. February 1, 1996; 109 ( Pt 2) 309-18.
XMCM7, a novel member of the Xenopus MCM family, interacts with XMCM3 and colocalizes with it throughout replication. , Romanowski P., Proc Natl Acad Sci U S A. September 17, 1996; 93 (19): 10189-94.
The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin. , Romanowski P., Curr Biol. November 1, 1996; 6 (11): 1416-25.
Cell cycle regulation of the replication licensing system: involvement of a Cdk-dependent inhibitor. , Mahbubani HM., J Cell Biol. January 13, 1997; 136 (1): 125-35.
A role for Cdk2 kinase in negatively regulating DNA replication during S phase of the cell cycle. , Hua XH., J Cell Biol. April 7, 1997; 137 (1): 183-92.
Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast. , Donovan S., Proc Natl Acad Sci U S A. May 27, 1997; 94 (11): 5611-6.
Licensing of DNA replication by a multi-protein complex of MCM/ P1 proteins in Xenopus eggs. , Kubota Y., EMBO J. June 2, 1997; 16 (11): 3320-31.
The replication licensing system. , Tada S., Biol Chem. January 1, 1998; 379 (8-9): 941-9.
Protein kinase inhibition in G2 causes mammalian Mcm proteins to reassociate with chromatin and restores ability to replicate. , Coverley D., Exp Cell Res. January 10, 1998; 238 (1): 63-9.
Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2. , Hua XH., J Cell Biol. January 26, 1998; 140 (2): 271-81.
Regulated chromosomal DNA replication in the absence of a nucleus. , Walter J ., Mol Cell. March 1, 1998; 1 (4): 519-29.
DNA replication in vertebrates requires a homolog of the Cdc7 protein kinase. , Roberts BT., Proc Natl Acad Sci U S A. March 16, 1999; 96 (6): 2800-4.
Mcm2, but not RPA, is a component of the mammalian early G1-phase prereplication complex. , Dimitrova DS., J Cell Biol. August 23, 1999; 146 (4): 709-22.
Cyclin A-dependent kinase activity affects chromatin binding of ORC, Cdc6, and MCM in egg extracts of Xenopus laevis. , Findeisen M., Eur J Biochem. September 1, 1999; 264 (2): 415-26.
The replication capacity of intact mammalian nuclei in Xenopus egg extracts declines with quiescence, but the residual DNA synthesis is independent of Xenopus MCM proteins. , Sun W., J Cell Sci. February 1, 2000; 113 ( Pt 4) 683-95.
The roles of the MCM, ORC, and Cdc6 proteins in determining the replication competence of chromatin in quiescent cells. , Madine MA., J Struct Biol. April 1, 2000; 129 (2-3): 198-210.
Central role for cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts. , Mimura S., Genes Cells. June 1, 2000; 5 (6): 439-52.
Evidence for sequential action of cdc7 and cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts. , Walter JC ., J Biol Chem. December 15, 2000; 275 (50): 39773-8.
Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins. , Gillespie PJ., BMC Biochem. January 1, 2001; 2 15.
Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle. , Okuno Y., EMBO J. August 1, 2001; 20 (15): 4263-77.
Mammalian nuclei become licensed for DNA replication during late telophase. , Dimitrova DS., J Cell Sci. January 1, 2002; 115 (Pt 1): 51-9.
Coordinated regulation of M phase exit and S phase entry by the Cdc2 activity level in the early embryonic cell cycle. , Iwabuchi M., Dev Biol. March 1, 2002; 243 (1): 34-43.
Xenopus Cdc6 performs separate functions in initiating DNA replication. , Frolova NS., Mol Biol Cell. April 1, 2002; 13 (4): 1298-312.
MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts. , Edwards MC., J Biol Chem. September 6, 2002; 277 (36): 33049-57.
Human Mcm proteins at a replication origin during the G1 to S phase transition. , Schaarschmidt D., Nucleic Acids Res. October 1, 2002; 30 (19): 4176-85.
Competence to replicate in the unfertilized egg is conferred by Cdc6 during meiotic maturation. , Lemaître JM., Nature. October 17, 2002; 419 (6908): 718-22.
The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication. , Van Hatten RA., J Cell Biol. November 25, 2002; 159 (4): 541-7.
CDK- and Cdc45-dependent priming of the MCM complex on chromatin during S-phase in Xenopus egg extracts: possible activation of MCM helicase by association with Cdc45. , Masuda T., Genes Cells. February 1, 2003; 8 (2): 145-61.
A role for Ran-GTP and Crm1 in blocking re-replication. , Yamaguchi R., Cell. April 4, 2003; 113 (1): 115-25.
A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication. , Kubota Y., Genes Dev. May 1, 2003; 17 (9): 1141-52.
CpG methylation of DNA restricts prereplication complex assembly in Xenopus egg extracts. , Harvey KJ., Mol Cell Biol. October 1, 2003; 23 (19): 6769-79.
DNA damage-induced replication arrest in Xenopus egg extracts. , Stokes MP., J Cell Biol. October 27, 2003; 163 (2): 245-55.
The regulation of competence to replicate in meiosis by Cdc6 is conserved during evolution. , Lemaître JM., Mol Reprod Dev. September 1, 2004; 69 (1): 94-100.
Functional domains of the Xenopus replication licensing factor Cdt1. , Ferenbach A., Nucleic Acids Res. January 12, 2005; 33 (1): 316-24.
Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extracts. , Tsuyama T., Nucleic Acids Res. February 1, 2005; 33 (2): 765-75.
ATM and ATR check in on origins: a dynamic model for origin selection and activation. , Shechter D ., Cell Cycle. February 1, 2005; 4 (2): 235-8.
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint. , Byun TS., Genes Dev. May 1, 2005; 19 (9): 1040-52.
ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks. , Trenz K., EMBO J. April 19, 2006; 25 (8): 1764-74.
Dynamics of DNA binding of replication initiation proteins during de novo formation of pre-replicative complexes in Xenopus egg extracts. , Waga S., J Biol Chem. April 21, 2006; 281 (16): 10926-34.
Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities. , Chang DJ., J Biol Chem. October 27, 2006; 281 (43): 32081-8.
Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts. , Errico A., Proc Natl Acad Sci U S A. September 18, 2007; 104 (38): 14929-34.
Plx1 is required for chromosomal DNA replication under stressful conditions. , Trenz K., EMBO J. March 19, 2008; 27 (6): 876-85.
Tipin/ Tim1/ And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion. , Errico A., EMBO J. December 2, 2009; 28 (23): 3681-92.
The DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation. , Chowdhury A., Mol Cell Biol. March 1, 2010; 30 (6): 1495-507.
Interaction of human MCM2-7 proteins with TIM, TIPIN and Rb. , Numata Y., J Biochem. June 1, 2010; 147 (6): 917-27.
G2 phase chromatin lacks determinants of replication timing. , Lu J., J Cell Biol. June 14, 2010; 189 (6): 967-80.
MCM-BP regulates unloading of the MCM2-7 helicase in late S phase. , Nishiyama A., Genes Dev. January 15, 2011; 25 (2): 165-75.
MCM2-7 form double hexamers at licensed origins in Xenopus egg extract. , Gambus A., J Biol Chem. April 1, 2011; 286 (13): 11855-64.